Search clinical trials for: drug interactions

Total 260159 results

National Cancer Institute, Naples

Recruiting

Nivolumab in mRCC Patients: Treg Function, T-cell Access and NK Interactions to Predict and Improve Efficacy (REVOLUTION)

Metastatic Renal Cell Carcinoma | RCC

Italy
Massachusetts General Hospital

Recruiting

Memantine for the Treatment of Social Deficits in Youth With Disorders of Impaired Social Interactions

Autism Spectrum Disorder | Autism | Nonverbal Learning Disability

United States
Hospices Civils de Lyon

Recruiting

Study of Olfaction / Vision Interactions in Expert and Novice Populations

Healthy

France
Johns Hopkins University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

INIA Stress and Chronic Alcohol Interactions: Glucocorticoid Antagonists in Heavy Drinkers

Alcohol Use Disorder

United States
National Institute on Drug Abuse (NIDA)
The Peter G. Dodge Foundation (PGDF)

Completed

Exploring Gut-Brain and Brain-Gut Interactions in Alcohol Use Disorder Via Microbiota Investigations: A Pilot Study

Alcoholism

United States
Biogen

Active, not recruiting

A Study to Assess the Potential for Gastric-pH Dependent Drug-Drug Interactions of BIIB122 With a Proton Pump Inhibitor in Healthy Participants

Healthy Volunteer

United States
Alexion Pharmaceuticals, Inc.

Completed

A Study to Investigate the Potential Drug Interactions Between ALXN2080 and Rosuvastatin and Metformin in Healthy Adult Participants

Healthy

United Kingdom
University of Utah
Agency for Healthcare Research and Quality (AHRQ)

Active, not recruiting

Shared Decision for Drug Interactions in Oral Anticoagulation (DDInteract)

Anticoagulants | Drug Interactions

United States
Radboud University Medical Center
Amgen

Completed

Rivaroxaban Sotorasib Interaction Study (ROSIE)

Drug Drug Interaction Study

Netherlands
Seattle Institute for Biomedical and Clinical Research
Genomind, LLC

Completed

Medication Optimization Using Pharmacogenetic Testing and the G-DIG to Reduce Polypharmacy in a Mental Health Population (MedOPT)

Pharmacogenetic Testing

United States
Pfizer

Completed

A Study to Learn About the Drug-drug Interactions of Sisunatovir in Healthy Adult Participants

Respiratory Syncytial Virus Infections

United Kingdom
University of Alabama at Birmingham
Merck Sharp & Dohme LLC; University of Washington; Wits Reproductive Health and...

Active, not recruiting

Evaluation of Pharmacokinetic Drug-drug Interactions Between Hormonal Contraceptives and Doravirine-containing ART Among Women Living With HIV in South Africa (EPIC)

HIV Infections | Contraception | Drug-drug Interaction

South Africa
AstraZeneca
Parexel

Completed

Study to Assess the Effect of Sodium Zirconium Cyclosilicate on the Pharmacokinetics of Tacrolimus and Cyclosporin in Healthy Subjects

Hyperkalaemia

Germany
Bristol-Myers Squibb

Completed

A Study Investigating Interactions Between BMS-986322 and Rosuvastatin, Metformin and Methotrexate in Healthy Participants

Healthy Participants

United States
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Pharmacokinetic Drug-drug Interactions Between VX-548, Midazolam, and Digoxin

Pain

United States
CTI BioPharma
PPD

Completed

Drug-Drug Interaction Study of Pacritinib and CYP450,Transporter Substrates, and CYP450 3A4 in Healthy Male Subjects

Drug Interactions

United States
Shanna Babalonis, PhD
National Institute on Drug Abuse (NIDA)

Completed

Opioid and Cannabinoid Interactions

Opioid Use | Marijuana Usage

United States
Celgene

Completed

A Study of Perpetrator Drug Interactions of Enasidenib in AML Patients

Leukemia, Myeloid, Acute

Korea, Republic of, Australia
Bellus Health Inc. - a GSK company

Completed

Evaluation of the Potential Drug-drug Interactions Between Gemfibrozil or Dabigatran Etexilate and Camlipixant

Healthy

Canada
Eli Lilly and Company

Completed

A Study of Lasmiditan in Healthy Volunteers

Healthy

Singapore
Sharon Walsh
National Institute on Drug Abuse (NIDA)

Completed

Prescription Medication Interactions

Opioid Use | Sedative Use

United States
Dong-A ST Co., Ltd.

Completed

Drug Interactions When DA-8010 is Co-administered With Paroxetine or Mirabegron in Healthy Adults

Healthy

Korea, Republic of
University of Pittsburgh

Active, not recruiting

Immune Interactions in Severe Asthma

Asthma

United States
The University of Hong Kong
Lok Sin Tong Benevolent Society, Kowloon

Active, not recruiting

Smoking Cessation Programme in Workplaces in Hong Kong (Phase Ⅴ)

Smoking Cessation

Hong Kong
Pop Test Oncology LLC
Baylor College of Medicine; Michael E. DeBakey VA Medical Center; Congressionally... and other collaborators

Completed

Effects of Ethanol on the Pharmacokinetics of PT-150 (Formerly ORG34517) (PT150 PK Study)

Potential Treatment for Alcohol Dependence-Alcohol Interaction

United States
National Institutes of Health Clinical Center (CC)

Completed

Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamics of Oral Anticoagulants (Rivaroxaban, Apixaban) in Health Volunteers

Healthy Volunteers

United States
Insel Gruppe AG, University Hospital Bern

Completed

Interaction of Sevoflurane Propofol and Remifentanil in Anesthesia for Laparoscopic Surgery (SPRV)

Drug Interactions | Anesthesia, Conduction

Switzerland
Redx Pharma Plc
Simbec Research

Completed

A 3-part Study to Evaluate Safety, Tolerability, Food Effect and Drug-drug Interactions of RXC007 in Healthy Volunteers

Liver Diseases | Fibrosis | Kidney Diseases | Inflammation | Idiopathic Pulmonary Fibrosis | Non-alcoholic Steatohepatitis

United Kingdom
Sumitomo Pharma America, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Drug Interaction Potential of Napabucasin in Healthy Volunteers

Drug-drug Interactions

United States
Innovent Biologics (Suzhou) Co. Ltd.

Completed

A Study to Evaluate the Drug-drug Interactions (DDIs) of IBI362 With Metformin, Warfarin, Atorvastatin, Digoxin in Overweight or Obese Subjects

Overweight Subjects | Obese Subjects

China
Jiangxi Qingfeng Pharmaceutical Co. Ltd.

Completed

A Study to Evaluate the Drug-drug Interactions (DDIs) of GP681 With Rosuvastatin, Digoxin, Itraconazole, Oseltamivir in Chinese Healthy Volunteers

Healthy Volunteers

China
Helen Reynolds
Desmond Tutu HIV Centre; Infectious Disease Institute, Kampala, Uganda

Active, not recruiting

Drug Interactions Between Dolutegravir and Escalating Doses of Rifampicin (DoRIS)

Tuberculosis | Hiv

Uganda, South Africa
Oregon Health and Science University

Enrolling by invitation

Assessing Patient-provider Interactions During the Preoperative Anesthesia Consult (IMPLICIT)

Healthcare Disparities | Minority Health | Racism

United States
Seoul National University Bundang Hospital

Enrolling by invitation

A Drug-drug Interaction Study to Evaluate the Effect of Rifampicin on the Pharmacokinetics of Methotrexate in Elderly Subjects

Drug Interactions

Korea, Republic of
Boryung Pharmaceutical Co., Ltd

Completed

A Study to Evaluate Drug-drug Interactions and Safety Between "BR3006-1", "BR3006-2", and "BR3006-3" in Healthy Volunteers

Diabetes Mellitus

Korea, Republic of
National Institutes of Health Clinical Center (CC)

Completed

Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy Volunteers (YODA)

Healthy Volunteers

United States
Dr. Noah Biotech Inc.

Completed

Multiple Dose Study to Evaluate Drug-drug Interactions, Safety and Tolerability of NDC-002 in Healthy Volunteers

Stroke | Stroke Sequelae

Korea, Republic of
MDI Health
Hadassah Medical Organization

Completed

Assessment of a Novel Algorithm System for Polypharmacy Patient Medication Safety and Consultation

Polypharmacy Patients

Israel
LI YAN

Completed

Effect of Azole/Echinocandin Use on Tacrolimus Pharmacokinetics

Kidney Transplant Patients

China
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Withdrawn

Pharmacokinetic Interactions of ENG Subdermal Implants With Long-Acting Cabotegravir (CAB-LA) and LA Rilpivirine (RPV-LA) (CARLA)

HIV-1-infection
National Institute of Allergy and Infectious Diseases...
ViiV Healthcare

Suspended

Drug-Drug Interactions Between Rifapentine and Dolutegravir in HIV/LTBI Co-Infected Individuals

HIV Infection | LTBI

United States, Haiti, Botswana, Brazil, Thailand, Zimbabwe, Malawi, Peru, South Africa
Botswana Harvard AIDS Institute Partnership
University of Liverpool

Active, not recruiting

Investigating the Interaction Between Two Long-acting Reversible Methods of Contraception and Dolutegravir, a Treatment for HIV (CODA)

Contraception | Human Immunodeficiency Virus | ART

Botswana
Johns Hopkins University
Washington State University; National Center for Complementary and Integrative...

Completed

Interactions Between Cannabinoids and Cytochrome P450-Metabolized Drugs

Drug-Interactions

United States
Thomas Jefferson University

Completed

Evaluating Drug Interactions Between Doravirine With Estradiol and Spironolactone in Healthy Transgender Women (IDENTIFY)

Gender Dysphoria | Transgender Women | Transgender Health | Human Immunodeficiency Virus

United States
Il-Yang Pharm. Co., Ltd.

Completed

Study to Evaluate Pharmacokinetic Drug Interactions and Safety of Ilaprazole and Aceclofenac

Drug Interaction Potentiation

Korea, Republic of
Il-Yang Pharm. Co., Ltd.

Completed

Study to Evaluate Pharmacokinetic Drug Interactions and Safety of Naproxen, Aceclofenac, Celecoxib and Ilaprazole

Drug Interaction Potentiation

Korea, Republic of
Dizal Pharmaceuticals

Completed

Drug-drug Interactions Between DZD9008 and Itraconazole/Carbamazepine

Healthy Subjects

United States
Columbia University

Active, not recruiting

Video Consultation to Reduce Drug Interactions Among Patients Initiating Oral Anti-Cancer Drugs

Cancer

United States
Damanhour University
Alexandria University

Completed

Potential Drug Interactions With Bisoprolol in Egyptian Patients With ACS

Acute Coronary Syndrome

Egypt
Purdue University
National Institutes of Health (NIH)

Terminated

Salivary Interactions With Chemosensations

Diet, Food Choice, Taste

United States

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