Search clinical trials for: varenicline

Total 350 results

Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Active, not recruiting

Metabolism Informed Smoking Treatment: The MIST RCT

Smoking

United States
Mayo Clinic

Completed

Varenicline For Smokers In Recovery From Alcohol Dependence

Tobacco Abstinence

United States
University of California, Los Angeles
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

A Novel Human Lab Model for Screening AUD Medications

Alcohol Use Disorder

United States
Centre for Addiction and Mental Health
Yale University; Oregon State University

Withdrawn

Combining rTMS With Varenicline to Prevent Smoking Lapse in Schizophrenia

Schizophrenia | Tobacco Use Disorder | Craving | Cognitive Functioning
University of Pennsylvania
Oyster Point Pharma, Inc.

Completed

Nasal Spray Study in Sjogren's Dry Eye Disease

Dry Eye | Sjogren's Syndrome

United States
University of Maryland, Baltimore
University of Kentucky; University of Maryland, College Park; University of Maryland...

Enrolling by invitation

Botswana Smoking and Abstinence Reinforcement Trial (BSMART)

Smoking Cessation | Hiv

Botswana
VA Office of Research and Development

Completed

Mobile Evidence-Based Smoking Cessation for Veterans Living With HIV (MESH) (MESH)

Smoking | Human Immunodeficiency Virus

United States
Pfizer
Karolinska Institutet; University of Aarhus

Completed

Varenicline Pregnancy Cohort Study

Malformations
University of Maryland, Baltimore
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Optimizing Smoking Cessation for People With HIV/AIDS Who Smoke

Smoking | HIV

United States
State University of New York at Buffalo
National Cancer Institute (NCI); Pfizer

Completed

EVarQuit: Extended Pre-quit Varenicline to Assist in Quitting Smoking (EVarQuit)

Tobacco Smoking

United States
University of California, San Diego
University of California; Veterans Medical Research Foundation

Completed

Novel Pharmacotherapy Approaches in Smokers With Serious Mental Illness

Schizophrenia | Schizoaffective Disorder | Bipolar Disorder | Nicotine Dependence

United States
Vance Thompson Vision ND

Completed

Investigator Initiated Study to Assess the Efficacy of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease Following Laser-assisted in Situ Keratomileusis (LASIK)

Dry Eye Disease

United States
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.
Oyster Point Pharma, Inc.

Completed

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of OC-01 in Adult Chinese With Dry Eye Disease

Dry Eye Disease

China
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.
Oyster Point Pharma, Inc.

Completed

Clinical Trial to Evaluate the Efficacy and Safety of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease

Dry Eye Disease

China
Centre for Addiction and Mental Health
Pfizer; Brainsway

Completed

Deep rTMS and Varenicline for Smoking Cessation

Smoking Cessation | Tobacco Use Disorder

Canada
University of Kansas Medical Center
National Institute on Drug Abuse (NIDA)

Completed

Individualizing Pharmacotherapy for African American Smokers

Smoking Cessation

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Bupropion Hydrochloride or Patient's Choice for Smoking Cessation in Patients With Squamous Cell Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy

Nasopharyngeal Carcinoma | Current Smoker | Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Hypopharyngeal Squamous Cell Carcinoma | Laryngeal Squamous Cell Carcinoma | Oral Cavity Squamous Cell Carcinoma

United States
Rose Research Center, LLC
Foundation for a Smoke-Free World

Completed

Efficacy and Tolerability of Combination Varenicline With Hydroxyzine as a Potential Smoking Cessation Treatment (HAVE)

Smoking Cessation | Nausea | Stress | Sleep Disturbance

United States
Pradeesh Sivapalan

Withdrawn

TOBacco STOP in Chronic Obstructive Pulmonary Disease-Trial - Study Protocol (TOB-STOP-COP)

Smoking Cessation | Lung Diseases, Obstructive | Chronic Obstructive Pulmonary Disease | Pulmonary Disease, Chronic Obstructive

Denmark
Mayo Clinic

Withdrawn

Feasibility of Treatment for Vaping Cessation (VAPEscape)

Vaping

United States
University of Wisconsin, Madison
Washington University School of Medicine; National Heart, Lung, and Blood Institute...

Completed

UW Quitting Using Intensive Treatment Study (QUITS) (QUITS)

Tobacco Dependence

United States
Rush University Medical Center

Completed

Varenicline for Gait and Balance Impairment in Parkinson Disease (Chantix-PD)

Parkinson Disease

United States
University of Sao Paulo General Hospital
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Efficacy of the Use of Genetic Markers in the Choice of the Pharmacological Treatment of Smoking (GENTSMOKING) (GENTSMOKING)

Smoking Cessation | Genetic Predisposition

Brazil
Center for Ophthalmic and Vision Research, LLC

Completed

OC-01 (Varenicline) Nasal Spray and Dry Eye Signs and Symptoms in Daily Disposable Contact Lens Wearers

Dry Eye

United States
University of Zagreb
Harvard Medical School (HMS and HSDM); University of Ljubljana School of Medicine... and other collaborators

Completed

Varenicline Versus Cytisine for Smoking Cessation in Primary Care Setting

Smoking Cessation

Croatia, Slovenia
Hutchmed

Completed

Fruquintinib DDI Study With P-gp and BCRP Substrates

Metastatic Colorectal Cancer

United States
Medical University of South Carolina

Completed

Translational Neuropsychopharmacology Research of Nicotine Addiction

Nicotine Dependence, Cigarettes

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Pfizer

Terminated

Management of Tobacco Treatment Intervention in Reducing Surgical Complications in Patients With Newly Diagnosed Lung Cancer Who Smoke Cigarettes

Lung Carcinoma

United States
Oyster Point Pharma, Inc.

Completed

Clinical Trial to Evaluate the Chronic Efficacy of OC-01 Nasal Spray on Signs of Dry Eye Disease (The MYSTIC Study)

Dry Eye Disease

Mexico
Oyster Point Pharma, Inc.

Completed

Evaluating Relative Bioavailability of OC-01 (Varenicline) Nasal Spray as Compared to Orally Administered Varenicline

Healthy Subjects

United States
Brown University

Terminated

Targeted Pharmacological and Behavioral Treatments for Smoking in Schizophrenia Study 1

Tobacco Dependence

United States
Arizona State University
National Institute on Drug Abuse (NIDA); Pfizer; University of Nevada, Reno; Los...

Completed

Varenicline OTC Trial on Efficacy and Safety (VOTC)

Smoking Cessation | Withdrawal Symptoms | Tobacco Dependence

United States
University of Maryland, Baltimore
National Institute on Drug Abuse (NIDA)

Completed

Comparison of Varenicline and Placebo for Smoking Cessation in Schizophrenia

Schizophrenia | Cigarette Smoking
Centre for Addiction and Mental Health

Completed

Using Non-invasive Brain Stimulation (tDCS) With Varenicline for Treating Tobacco Dependence

Smoking Cessation | Tobacco Smoking | Tobacco Use Disorder | Substance Use Disorders | Molecular Mechanisms of Pharmacological Action | Tobacco Dependence | Physiological Effects of Drugs

Canada
Rose Research Center, LLC
Foundation for a Smoke-Free World

Completed

Combination of E-cigarettes and Varenicline for Tobacco Harm Reduction (EVAR)

Smoking Cessation | Harm Reduction

United States
University of Maryland, Baltimore
Stanley Medical Research Institute

Completed

Varenicline Adjunctive Treatment in Schizophrenia

Schizophrenia | Schizoaffective Disorder | Schizophreniform Disorder

United States
Oyster Point Pharma, Inc.

Completed

Efficacy of OC-01 Nasal Spray on Goblet Cell and Meibomian Gland Stimulation

Dry Eye Disease

United States
M.D. Anderson Cancer Center
National Institute on Drug Abuse (NIDA); Pfizer; National Institutes of Health...

Completed

Combining Varenicline and Bupropion for Smoking Cessation

Smoking Cessation

United States
Won Choi, PhD, MPH
National Cancer Institute (NCI)

Completed

Web-based Smoking Cessation Program for Tribal College Students

Smoking Cessation

United States
Oyster Point Pharma, Inc.

Completed

Evaluation of the Efficacy and Safety of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye Disease

Dry Eye Disease (DED)

United States
Oyster Point Pharma, Inc.

Completed

Evaluation of the Efficacy of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye Disease

Dry Eye Disease

United States
Shaare Zedek Medical Center

Completed

Extended (6-Week) Varenicline Preloading: Does it Facilitate Smoking Reduction and Cessation?

Smoking Cessation

Israel
University of Chicago
Pfizer

Completed

Varenicline Augmentation of Patch Outcomes in Heavy Drinkers' Smoking Cessation

Alcohol Drinking | Smoking Cessation

United States
Duke University
National Institute on Drug Abuse (NIDA)

Withdrawn

Mobile Health Interventions for Medication Adherence Among PLWH (HIVSMART)

Smoking | Smoking Cessation | HIV/AIDS | HIV
University of Auckland, New Zealand
Brunel University; Lakes District Health Board

Completed

Cytisine Versus Varenicline for Smoking Cessation (RAUORA)

Smoking Cessation

New Zealand
Duke University
National Institute on Drug Abuse (NIDA); Pfizer

Completed

Adaptive Pharmacotherapy for Smoking Cessation

Nicotine Dependence

United States
Yale University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Varenicline for Smoking Cessation in Heavy Drinking Smokers

Smoking | Nicotine Dependence | Heavy Drinking
Northwestern University
National Cancer Institute (NCI)

Completed

Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers

Major Depressive Disorder | Nicotine Dependence

United States
University of California, Los Angeles
National Institute on Drug Abuse (NIDA)

Completed

Combining Varenicline and Naltrexone for Smoking Cessation

Alcohol Use Disorder | Nicotine Dependence

United States
Mayo Clinic
National Institute on Drug Abuse (NIDA)

Terminated

Addressing Post Cessation Weight Gain

Smoking Cessation | Obesity

United States

Search clinical trials for: varenicline

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