Search clinical trials for: PK Deficiency

Total 13058 results

Merck Sharp & Dohme LLC

Unknown

Safety and Effectiveness of an Anti-HIV Drug Combination Taken Twice Daily

HIV Infections

United States
ICN Pharmaceuticals

Terminated

The Safety and Effectiveness of Ribavirin in the Early Stages of HIV-Infection

HIV Infections
Hoffmann-La Roche

Completed

The Safety and Effectiveness of Ganciclovir Plus Interferon Beta in Preventing the Return of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States
The Immune Response Corporation

Completed

A Multicenter, Double-Blind, Phase III, Adjuvant-Controlled Study of the Effect of 10 Units of HIV-1 Immunogen (Remune) Compared to Incomplete Freund's Adjuvant (IFA) Alone Every 12 Weeks on AIDS-Free Survival in Subjects With HIV Infection and CD4 T-Lymphocytes Between 300 and 549 Cells/microL Rega

HIV Infections

United States
LXR Biotechnology

Completed

A Study of LXR015-1 in HIV-Infected Patients

HIV Infections

United States
Hoffmann-La Roche

Completed

A Study of Saquinavir Soft Gelatin Capsules Plus Zidovudine Plus Lamivudine in the Treatment of HIV-1 Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
Hoffmann-La Roche

Completed

A Comparison of Saquinavir Hard- and Soft-Gelatin Capsules in HIV-Infected Patients

HIV Infections

United States
VaxGen

Completed

A Study of AIDSVAX B/B and AIDSVAX B/E, Two Possible Vaccines

HIV Infections

United States
Weill Medical College of Cornell University

Completed

A Study of Three Drug Combination Therapies in HIV-Infected Patients Who Have Never Been Treated With Anti-HIV Drugs

HIV Infections

United States
Gilead Sciences

Completed

Safety and Effectiveness of Adding PMPA Prodrug to an Anti-HIV Drug Combination to Treat HIV-Infected Patients

HIV Infections

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of Three Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Taken AZT

HIV Infections

United States, Canada, Puerto Rico
Hoffmann-La Roche

Completed

A Study to Compare the Effects of Two Anti-HIV Drug Combinations on the Immune Systems of HIV-Infected Patients

HIV Infections

United States
National Center for Research Resources (NCRR)
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Study of Gonadotropin-Releasing Hormone Pulse Frequency in Sexual Maturation and in the Menstrual Cycle

Precocious Puberty | Hypogonadism

United States
Steinhart Medical Associates

Unknown

Treatment of Advanced AIDS Patients With Dextrin Sulfate

HIV Infections

United States
Merck Sharp & Dohme LLC

Unknown

The Safety and Effectiveness of Indinavir Plus Ritonavir Plus Two NRTIs in HIV-Infected Patients Who Need Early Intervention Treatment

HIV Infections

United States
Hoffmann-La Roche
Trimeris

Completed

T-20 in HIV Patients With Prior Drug Treatment and/or Resistance to Each of the Three Classes of Anti-HIV Drugs

HIV Infections

Switzerland, Spain, United Kingdom, Germany, Belgium, Australia, Sweden, Italy, Netherlands
Hoffmann-La Roche

Completed

A Study of Zidovudine (AZT) Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Patients With Little or No Previous Treatment

HIV Infections

United States, Puerto Rico
Glaxo Wellcome

Completed

A Study of 1592U89 and Ethanol When Given Together to HIV-Infected Patients

HIV Infections

United States
Boehringer Ingelheim

Completed

An Open-Label Study in HIV+ Patients to Determine the Effects of Nevirapine (Viramune) on the Pharmacokinetics of Clarithromycin and Activity of Cytochrome 3A4.

HIV Infections

United States
National Center for Research Resources (NCRR)
Northwestern University

Completed

Study of Pituitary Size and Function in Familial Dwarfism of Sindh

Growth Hormone Deficiency
Eunice Kennedy Shriver National Institute of Child...
Children's National Research Institute

Terminated

Phase I Pilot Study of Liver-Directed Gene Therapy for Partial Ornithine Transcarbamylase Deficiency

Ornithine Transcarbamylase Deficiency Disease
Merck Sharp & Dohme LLC

Unknown

Safety and Effectiveness of Giving Indinavir, Ritonavir, Stavudine, and Lamivudine to HIV-Infected Patients Who Have Never Received Anti-HIV Drugs

HIV Infections

United States
Shaman Pharmaceuticals

Completed

SP-303T Applied to the Skin of Patients With Herpes Simplex Virus (HSV) Infection and AIDS Who Have Not Had Success With Acyclovir

HIV Infections | Herpes Simplex

United States
Liposome

Completed

Safety and Efficacy of Amphotericin B Lipid Complex in the Treatment of Cryptococcal Meningitis in Patients With the Acquired Immunodeficiency Syndrome

HIV Infections | Meningitis, Cryptococcal

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I Safety and Immunogenicity Trial of UBI SynVac (HIV-1 MN Octameric V3 Peptide Vaccine)

HIV Infections

United States
Boehringer Ingelheim

Completed

A Multi-Center, Placebo-Controlled, Double-Blind, Randomized Trial Comparing the Virologic and Immunologic Activities of 400 Mg Nevirapine in Combination With Zidovudine Versus Zidovudine Alone in Asymptomatic HIV-1 Infected Patients With 4-12 Months of Prior Zidovudine Therapy and 200-500 CD4+ Cell

HIV Infections

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of Lamivudine Plus Zidovudine, Used With and Without 1592U89, in HIV-1 Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States, Canada, Puerto Rico
PharmaResearch

Unknown

Comparing Side Effects of Two Forms of Videx in HIV-Infected Adults

HIV Infections

United States
Dupont Merck

Completed

A Study of Efavirenz in Combination With Stavudine and Didanosine

HIV Infections

United States
Hoffmann-La Roche

Completed

The Safety and Effectiveness of Saquinavir Soft Gelatin Capsules Combined With Other Anti-HIV Drugs

HIV Infections

United States
Agouron Pharmaceuticals

Completed

Viracept Expanded Access Program

HIV Infections

United States
Ortho Pharmaceuticals

Completed

A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of Subcutaneous Doses of r-HuEPO in AIDS Patients With Anemia Induced by Their Disease and AZT Therapy

HIV Infections | Cytopenias

United States
Fairview University Medical Center

Completed

Study of Allogeneic Bone Marrow Transplantation Following Cyclophosphamide and Radiotherapy in Patients With Myelodysplastic Syndrome and Acute Leukemia Related to Fanconi's Anemia

Myelodysplastic Syndromes | Leukemia, Lymphocytic, Acute | Fanconi's Anemia | Leukemia, Nonlymphocytic, Acute

United States
Genentech, Inc.

Completed

A Phase I Study of the Safety and Immunogenicity of Rgp 120/HIV-1IIIB Vaccine in HIV-1 Seropositive Adult Volunteers

HIV Infections

United States
Glaxo Wellcome

Completed

A Dose-Frequency Trial of Oral Retrovir in Patients With AIDS or Severe ARC

HIV Infections

United States
Newport Pharmaceuticals International

Completed

A Double-Blind Placebo Controlled Study To Determine the Optimal Immunopharmacological Dose Level of Isoprinosine in Immunodepressed Volunteers

HIV Infections

United States
AJI Pharma USA

Completed

Phase I/II Study of the Tolerance and Efficacy of Combined Use of Didanosine (2',3'-Dideoxyinosine; ddI) and Lentinan in HIV-Positive Patients

HIV Infections

United States
Hoechst Marion Roussel

Completed

A Study of the Safety and Efficacy of Chronically Administered MDL 28,574A in the Treatment of HIV-Infected Patients

HIV Infections

United States
Pharmacia and Upjohn

Completed

Safety and Effectiveness of Giving Combinations of Three or Four Anti-HIV Drugs to HIV-Infected Patients

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Computer-Assisted Adherence Program for Patients Taking Anti-HIV Drugs

HIV Infections | Acquired Immunodeficiency Syndrome

United States
Glaxo Wellcome

Completed

A Study of Retrovir in the Prevention of HIV Infection in Health Care Workers Accidentally Exposed to the Virus

HIV Infections

United States
Interferon Sciences

Completed

Double-Blind, Randomized, Placebo-Controlled Study of Low Dose Oral Interferon Alfa-n3 (Human Leukocyte Derived) in ARC Patients

HIV Infections

United States
Mylan Laboratories

Completed

A Phase II/III Study of Cysteamine (Mercaptoethylamine) and Zidovudine for the Treatment of HIV Disease

HIV Infections

United States
Eunice Kennedy Shriver National Institute of Child...
University of Washington

Unknown

Study of Genetic and Molecular Defects in Primary Immunodeficiency Disorders

Wiskott-Aldrich Syndrome | Leukocyte Adhesion Deficiency Syndrome | X-Linked Agammaglobulinemia | X-Linked Hyper IgM Syndrome

United States
National Center for Research Resources (NCRR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University...

Completed

Phase II Randomized Study of the Effects of Growth Hormone on Children and Adolescents on Maintenance Dialysis

End Stage Renal Disease | Renal Osteodystrophy

United States
Glaxo Wellcome

Completed

A Study of the Safety and Effectiveness of Combination Anti-HIV Therapy in HIV-Infected Adults

HIV Infections

United States
Argus Pharmaceuticals

Completed

A Study of Nystatin in HIV-Infected Patients

HIV Infections

United States
The Immune Response Corporation

Completed

An Expanded Access Open Label Protocol of Remune (HIV-1 Immunogen) in HIV-1-Infected Adults With CD4 Count 550 Cells /Ml and Greater.

HIV Infections

United States
GlaxoSmithKline

Unknown

Safety and Effectiveness of TRIZIVIR (Abacavir/Lamivudine/Zidovudine) With Efavirenz in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
Hoffmann-La Roche

Completed

A Study of Saquinavir and Zalcitabine, Used Alone and Together, in the Treatment of Advanced HIV Infection in Patients Who Stopped Taking or Who Cannot Take Zidovudine

HIV Infections

United States, Puerto Rico, Canada

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