Search clinical trials for: Antiretrovirals

Total 192 results

Hoffmann-La Roche

Completed

Efficacy, and Safety Study of Optimized Background Antiretroviral Regimen (OB) in Combination With Enfuvirtide in the Treatment-Experienced Participants With Human Immunodeficiency Virus-1 (HIV-1) Infection

HIV Infections

France
Henry M. Jackson Foundation for the Advancement...
US Military HIV Research Program; Janssen Vaccines & Prevention B.V.

Withdrawn

Safety and Efficacy of Neutralizing Antibodies and Vaccination for Induction of HIV Remission (RV582)

HIV-1-infection

Thailand
Hospital Clinic of Barcelona

Completed

Effectiveness of Raltegravir-Based Antiretroviral Therapy in HIV-HCV Coinfected Liver Transplant Recipients (RAL-LT-HIV)

Liver Transplantation | HIV Infections | Antiretroviral Therapy
University of Zurich

Unknown

Early Simplified: A Trial to Compare the Efficacy of Standard of Care Combination Antiretroviral Therapy With a Simplified Dolutegravir Monotherapy in Patients With a Primary HIV-1 Infection

Treatment Efficacy | Monotherapy | Dolutegravir | Primary HIV Infection

Switzerland
Hoffmann-La Roche

Completed

A Study to Evaluate the Safety and Efficacy of Adding Enfuvirtide to Oral Highly Active Antiretroviral Therapy (HAART) in Human Immunodeficiency Virus (HIV) Patients With Prior Treatment Experience (INTENSE)

HIV Infections

France, Germany, Spain, Italy, United States, Switzerland, Netherlands, Mexico, Canada, Israel
Kasr El Aini Hospital

Completed

Comparison Between Three Norepinephrine Bolus Doses for Management of Post-spinal Hypotension During Ceaserian Section for Patients With Preeclampsia

Cesarean Section Complications | Anesthesia; Adverse Effect

Egypt
McGill University Health Centre/Research Institute...
Merck Sharp & Dohme LLC

Completed

Raltegravir-based Antiretroviral Versus Maintaining Any Other Antiretroviral Therapy in HIV Mono-infected Patients

Fatty Liver | HIV | Nonalcoholic Steatohepatitis

Canada
French National Agency for Research on AIDS and...
Hoffmann-La Roche

Completed

Efficacy of Pegylated Interferon on Liver Fibrosis in Co-infected Patient With HIV and Hepatitis C

HIV Infections | Hepatitis C, Chronic

France
Viriom

Completed

Efficacy, Safety and Optimal Dose of VM-1500 in Comparison to Efavirenz Added to Standard-of-care Antiretroviral Therapy

HIV-1-infection

Russian Federation
Medical University of Warsaw

Completed

Normal Versus Dual Wave Insulin Bolus for High-protein Food

Type 1 Diabetes

Poland
Medical Research Council
NHS Health Technology Assessment Programme

Unknown

Protease Inhibitor Monotherapy Versus Ongoing Triple-therapy in the Long Term Management of HIV Infection (PIVOT) (PIVOT)

Acquired Immunodeficiency Syndrome | HIV Infection
Germans Trias i Pujol Hospital
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la...

Completed

HIV-1 Viral Dynamics in Subjects Initiating Raltegravir Therapy in Spain

HIV Infections

Spain
Pfizer

Completed

A Single Dose Study Of Antimineralocorticoid Activity Of PF-03882845 In Healthy Volunteers

Healthy Volunteers

United States
AstraZeneca
Eli Lilly and Company

Completed

A Trial Comparing Two Therapies: Basal Insulin/Glargine, Exenatide and Metformin Therapy (BET) or Basal Insulin/Glargine, Bolus Insulin Lispro and Metformin Therapy (BBT) in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus

Sweden, Italy, Korea, Republic of, Mexico, Russian Federation, Spain, Estonia, Romania, Finland, Netherlands, Argentina, Belgium, Germany, Portugal, United Kingdom, Greece, France, Puerto Rico
Northwestern University
Bristol-Myers Squibb

Completed

Switch to Atazanavir and Brachial Artery Reactivity (SABAR) Study (SABAR)

HIV Infection | Hyperlipidemia

United States, Argentina, Italy
Augusta University

Completed

Contribution of Dolutegravir to Obesity and Cardiovascular Disease

Vascular Diseases | Body Weight Changes | Cardiovascular Abnormalities | HIV-1-infection | Body Fat Disorder | HIV-Associated Lipodystrophy Syndrome | Antiviral Drug Adverse Reaction | Abnormality of Adipose Tissue

United States
Pangaea Global AIDS Foundation
National Institute on Drug Abuse (NIDA); Muhimbili University of Health and...

Unknown

Study of Integrating Antiretroviral Therapy With Methadone Treatment for People Who Inject Drugs (IMAT)

HIV | Opioid Dependence
Copenhagen University Hospital, Hvidovre
University Hospital Bispebjerg and Frederiksberg

Recruiting

Hemodynamic Measurements of Macrocirculatory and Perfusion Parameters in ICU

Septic Shock | Vasoconstriction | Hemodynamic Instability

Denmark
PETHEMA Foundation

Completed

LINFOTARGAM: Treatment With Chemotherapy Plus Rituximab and Highly Active Antiretroviral Therapy in Patients With Diffuse Large B Cell Lymphoma and Infection With the Human Immunodeficiency Virus (HIV) (LINFOTARGAM)

HIV Infections | Diffuse Large B Cell Lymphoma

Spain
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Diastolic Performance and Norepinephrine in Spinal-Induced Hypotension for Cesarean Delivery (NORA-CS)

Hypotension

Italy
Columbia University
National Institute of Allergy and Infectious Diseases (NIAID); New York University and other collaborators

Completed

Link4Health: A Combination Strategy for Linkage and Retention, Swaziland (L4H)

HIV (Human Immunodeficiency Virus)

Swaziland
Germans Trias i Pujol Hospital

Completed

Switching From Protease Inhibitor (PI) to Etravirine in HIV-1 Infected Subjects With Viremia Suppression

HIV

Spain
Indiana University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Pentoxifylline and Combination Antiretroviral Therapy to Improve Blood Vessel Function in HIV-Infected People

Cardiovascular Diseases | Vascular Diseases | HIV Infections | Atherosclerosis | HIV

United States
National Institute of Allergy and Infectious Diseases...
ANRS, Emerging Infectious Diseases

Completed

Phase II/III Study Evaluating the Effect of IL-2 on Preservation of the CD4 T-Lymphocytes After Interruption of Antiretroviral Treatment in HIV-Infected Patients With CD4 T-Lymphocyte Count Greater Than 500 Cells/mm3 Who Received Antiretroviral Tx (ILIADE)

HIV Infections

United States, France
The Hospital for Sick Children

Completed

Preventing Linear Growth Faltering Among Low Birth Weight Infants in Bangladesh

Infant, Low Birth Weight

Canada, Bangladesh
Institute for Interdisciplinary Infectiology
Hoffmann-La Roche

Unknown

Cohort Study for Patients Using Fuzeon (Enfuvirtide)

HIV Infections | Antiretroviral Treatment

Germany
University of California, San Francisco
National Institute of Mental Health (NIMH); Gilead Sciences; UZ-UCSF Collaborative...

Completed

The Impact and Cost-effectiveness of Safer Conception Strategies for HIV-discordant Couples (SAFER) (SAFER)

HIV Infections

Zimbabwe
Surface Ophthalmics, Inc.

Completed

Research Study To See How Well An Eye Drop (SURF-200) Works, What Side Effects There Are, And To Compare It With Vehicle In Subjects With An Episodic Flare-Up of Dry Eye Disease

Dry Eye Disease

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Pharmacokinetics, Safety, and Tolerability of Doravirine (MK-1439) and Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate (MK-1439A) in HIV-1-Infected Children and Adolescents

HIV Infections

United States, South Africa, Thailand
Imperial College London
Medical Research Council; University of Oxford; Guy's and St Thomas' NHS Foundation... and other collaborators

Completed

Research In Viral Eradication of HIV Reservoirs (RIVER)

HIV

United Kingdom
Babafemi Taiwo
ViiV Healthcare

Completed

Dolutegravir Antiretroviral Strategy to Promote Improvement and Reduce Drug Exposure (ASPIRE)

HIV Infection

United States
MRC/UVRI and LSHTM Uganda Research Unit
Janssen Pharmaceuticals

Recruiting

Improving HIV-1 Control in Africa With Long Acting Antiretrovirals (IMPALA)

HIV-1-infection

South Africa, Kenya, Uganda
ANRS, Emerging Infectious Diseases

Unknown

Third Line Antiretroviral Treatment Optimization in Sub-Saharan Africa (THILAO)

HIV Infection

Burkina Faso, Côte D'Ivoire, Mali, Senegal
Catholic University of the Sacred Heart

Terminated

Switch to Darunavir/r + Maraviroc Quaque Die in Patients With R5 Tropism by Viral DNA Genotyping (GUSTA) (GUSTA)

HIV Infection

Italy
LI Taisheng

Unknown

Impact on T Cell Immune Activation and Inflammation of Triptolide Woldifii in HIV-infected Immunological Non-responders (CACTrip12)

HIV

China
University of Colorado, Denver
Gilead Sciences

Terminated

Rapid Start vs. Standard Start Antiretroviral Therapy (ART) in HIV (B-HASTE)

HIV/AIDS

United States
Halozyme Therapeutics

Completed

CONSISTENT 1: Metabolic and Safety Outcomes of Hylenex Recombinant (Hyaluronidase Human Injection) Preadministered at CSII Infusion Site in Participants With Type 1 Diabetes Mellitus (T1DM)

Type 1 Diabetes Mellitus

United States
GlaxoSmithKline

Completed

Single Dose Pharmacokinetic (PK) Study Of Paroxetine CR(12.5-37.5mg) In Healthy Chinese Subjects

Depressive Disorder

China
GlaxoSmithKline

Completed

A Local Register Study For Major Depression Of Paroxetine Controlled Release

Depressive Disorder, Major | Major Depressive Disorder (MDD)

China
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy...

Terminated

Evaluation of 3TC or FTC Mono-therapy Compared to Continuing HAART as a Bridging Strategy (P1094)

HIV Disease

United States, Puerto Rico, Argentina, Brazil, Thailand
Brigham and Women's Hospital
The Fenway Institute

Recruiting

Next Generation Ingestible Sensors for Medication Adherence Measurement (NextGen)

HIV Infection | Adherence, Medication | Antiretroviral Therapy | Adherence, Treatment | Pre-Exposure Prophylaxis

United States
LI Taisheng

Completed

Safety and Efficacy Study of TwHF in HIV Patients With Poor Immune Responses

HIV

China
National Institute of Allergy and Infectious Diseases...

Completed

Controlling Acute or Early HIV Infection With Antiretroviral Drugs, Without a Candidate Vaccine.As Reported Previously, the Candidate Vaccie Was Not Provided by the Maufacturer as Promised

HIV Infections

United States, Canada
Sanofi

Completed

An Eight-week Study Evaluating the Efficacy and Tolerability of Two Doses of SSR149415 in Outpatients With Generalized Anxiety Disorder

Anxiety Disorders

United States
Muhimbili University of Health and Allied Sciences
Fogarty International Center of the National Institute of Health; Kumamoto...

Suspended

The Effect of Aspirin on HIV Disease Progression Among HIV- Infected Individuals Initiating Anti- Retroviral Therapy

Cardiovascular Diseases | Hiv

Tanzania
National Institute of Allergy and Infectious Diseases...

Completed

Selective Estrogen Receptor Modulators to Enhance the Efficacy of Viral Reactivation With Histone Deacetylase Inhibitors

HIV Infections

United States, Puerto Rico
Thomas Jefferson University

Enrolling by invitation

PET-MRI in Chronic Traumatic Brain Injury (CTBI) (PET-MRIcTBI)

Chronic Traumatic Brain Injury

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Interferon Alfa Sensitivity in HIV/HCV Persons Before and After HIV Meds

HIV Infection | Hepatitis C

United States
Oizumi Hospital

Unknown

Benefits of Switching Antidepressants Following Early Nonresponse

Depression

Japan
University of Maryland, Baltimore
Janssen Scientific Affairs, LLC

Recruiting

High-Risk Metachronous Oligometastatic Prostate Cancer Trial (KNIGHTS)

Prostate Cancer | Oligometastatic Disease

United States

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