Search clinical trials for: Tolvaptan IR

Total 435 results

AMO Development, LLC

Recruiting

Wavefront-guided LASIK for Monovision Treatment of Myopic Subjects With Presbyopia

Refractive Error

United States
Elcelyx Therapeutics, Inc.

Completed

Dose-Ranging Study to Evaluate the Glycemic Effects, Safety, and Tolerability of Metformin Delayed Release in Subjects With T2DM

Type 2 Diabetes Mellitus

United States, Puerto Rico
Orion Corporation, Orion Pharma

Completed

Pharmacokinetic Study of Multiple Doses of ORM-12741 (Nebula PK 2)

Healthy

Finland
Orion Corporation, Orion Pharma

Completed

Pharmacokinetic Study of Single Doses of ORM-12741 (Nebula PK 1)

Healthy

Finland
Pfizer
Medivation, Inc.

Completed

A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine)

Huntington Disease | Alzheimer's Disease

United States
Bristol-Myers Squibb

Completed

Phase 4: Investigational Study to Evaluate Metformin XR Monotherapy Versus Metformin IR Monotherapy in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus

South Africa, United States, Canada, Puerto Rico, Hungary, Germany, Czechia, Poland, Romania, United Kingdom
Emory University

Completed

AiDing Diuresis wIth Tolvaptan (ADD-IT) (ADD-IT)

Congestive Heart Failure | Cardiomyopathy

United States
Infrared Cameras Incorporate

Completed

A Study to Validate Comparability of an Infrared Thermographic Camera Versus Oral, Forehead, and Ear Thermometers When Determining Body Temperature in Adult Participants

Temperature Change, Body

United States
Shanghai Chest Hospital

Completed

The Safety and Efficacy of Tolvaptan for Patients With Tricuspid Regurgitation and Right Heart Failure After Left Heart Valves Replacement

Right Heart Failure | Tricuspid Regurgitation

China
Otsuka Pharmaceutical Co., Ltd.

Completed

Clinical Pharmacology Trial to Investigate the Dose of OPC-61815 Injection Equivalent to Tolvaptan 15-mg Tablet in Patients With Congestive Heart Failure

Congestive Heart Failure

Japan
Vanderbilt University

Completed

Comparison of Oral or Intravenous Thiazides vs Tolvaptan in Diuretic Resistant Decompensated Heart Failure

Heart Failure

United States
The Christ Hospital

Completed

Tolvaptan/Ultrafiltration in the Treatment of Acute Heart Failure (TUF)

Acute Decompensated Heart Failure

United States
Elcelyx Therapeutics, Inc.

Completed

Assessing the PK of Met DR, Met IR, and Met XR in Healthy Subjects

Healthy Subjects
Endo Pharmaceuticals

Completed

Open-Label Safety and Tolerability Study of Oxymorphone for Acute Postoperative Pain in Pediatric Subjects.

Postoperative Pain

United States
Alexion

Recruiting

A Study to Investigate the Pharmacokinetic Profile of ALXN2050 Modified Release Prototype Formulations and Immediate Release Reference Tablet in Healthy Adult Participants

Healthy Participants

United Kingdom
Kowa Research Institute, Inc.

Completed

Study to Investigate the Efficacy and Pharmacokinetic Profile of K-877-ER Compared to K-877-IR

Dyslipidemia

United States
Yonsei University

Recruiting

Respiratory Measurement Using Infrared Camera and Electrical Impedance Tomography for Sedation in Patients Undergoing TURP/TURB Under Spinal Anesthesia

Patients Undergoing Transurethral Prostate or Cystectomy Under Spinal Anesthesia

Korea, Republic of
Ottawa Hospital Research Institute
Carleton University

Completed

NEC Thermography Infrared Imaging Study

Necrotizing Enterocolitis

Canada
Neurovance, Inc.

Completed

A Study to Evaluate the Safety, Tolerance, and Pharmacokinetic and Pharmacodynamic Profile Of 1 SR Formulation of EB-1020

Normal, Healthy Volunteers

Australia
Bayer

Completed

Relative Bioavailability and Food Effect Study With Vericiguat to Characterize the Pediatric Formulation in Adult Healthy Subjects

Pharmacokinetics

Germany
Stallergenes Greer

Completed

Efficacy and Safety of 300 IR Sublingual Immunotherapy (SLIT) Tablets in Children Suffering From Grass Pollen Rhinoconjunctivitis

Allergy

Germany
GlaxoSmithKline

Completed

Clinical Evaluation of Ropinirole Prolonged Release/Extended Release (PR/XR) Tablet for Adjunctive Therapy to L-dopa in Subjects With Advanced Parkinson's Disease

Parkinson Disease

Japan
Stallergenes Greer

Completed

Safety and Efficacy Study of Sublingual Immunotherapy (SLIT) to Treat House Dust Mite Allergic Rhinitis

Allergic Rhinitis
AstraZeneca

Terminated

Study of Saxagliptin, 5-Hydroxy Saxagliptin, and Metformin Concentrations/Levels in Pediatric Subjects With T2DM

Type 2 Diabetes Mellitus

United States
Mundipharma Research Limited

Completed

Study to Assess Pharmacokinetic (PK), Bioavailability & Food Effect of MR902 Compared With Immediate Release (IR) Morphine Sulphate Oral Solution

Opioid Substitution Treatment
Oakland University
Georgetown University

Completed

V2 Receptor Effects on Fluid Regulation and Performance

Hyponatremia | Hypernatremia | Electrolyte Imbalance

United States
Merck KGaA, Darmstadt, Germany

Completed

Prednisone Timed-Release Tablet (TRT) Study: Modified-Release (MR) Formulation of Prednisone Compared to Standard Immediate-Release (IR) Prednisone in Participants With Rheumatoid Arthritis

Rheumatoid Arthritis

Poland, Germany
Ferrer Internacional S.A.

Terminated

Single Dose Study to Compare the Pharmacodynamics of Torasemide-PR 10 mg,Torasemide-IR 10 mg and Furosemide-IR 40 mg in Patients With Compensated Heart Failure

Compensated Heart Failure

Spain
Pfizer

Not yet recruiting

A Study to Learn How Different Forms of the Study Medicine Called PF-06954522 Are Taken up Into the Blood in Healthy Adults

Healthy Participants

United States
Stallergenes Greer

Completed

Efficacy and Safety of Sublingual Tablets of Grass Pollen Allergen Extract

Seasonal Allergic Rhinitis

Austria
Cairo University

Completed

Mobilization for Post Partum Low Back Pain

Low Back Pain, Mechanical

Egypt
University Hospital, Clermont-Ferrand

Completed

Model-based Iterative Reconstruction (MB-IR VEOTM) in Ultra Low-dose Abdominal CT Versus Adaptative Statistical Iterative Reconstruction (ASIR): A Prospective Study for Acute Renal Colic (VEOLITH)

Model-based Iterative Reconstruction (MB-IR VEOTM)

France
Ultragenyx Pharmaceutical Inc

Completed

An Open Label Phase 2 Extension Study of Higher Dose Sialic Acid-Extended Release (SA-ER) Tablets and Sialic Acid-Immediate Release (SA-IR) Capsules in Patients With Glucosamine (UDP-N-acetyl)-2-Epimerase (GNE) Myopathy

GNE Myopathy | Hereditary Inclusion Body Myopathy (HIBM)

United States, Israel
Janssen Research & Development, LLC

Completed

A Study of Canagliflozin and Metformin Immediate Release (50 mg/500 mg) FDC Tablets in Healthy Volunteers

Healthy

United States
Janssen Research & Development, LLC

Completed

A Study of Canagliflozin and Metformin Immediate Release (150 mg/500 mg) FDC Tablets in Healthy Volunteers

Healthy

United States
AstraZeneca

Completed

Compare the Effect on Cognitive Functioning of Two Formulations of Seroquel, Seroquel XR and IR in Patients With Stable Schizophrenia (eXtRa)

Schizophrenia

Italy, Germany, Austria, Spain, Denmark
Abbott
AbbVie; Parexel; Datamap; LKF Laboratorium für Klinische Forschung GmbH; Analytical... and other collaborators

Completed

Efficacy and Safety Study of Creon IR in Subjects With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

Exocrine Pancreatic Insufficiency in Subjects With Cystic Fibrosis

Spain, Czech Republic, Hungary, Poland
Otsuka Pharmaceutical Development & Commercialization...
PRA Health Sciences

Completed

Trial to Assess the Bioavailability of Quetiapine Versus Seroquel® in Subjects With Schizophrenia or Bipolar Disorder

Schizophrenia | Bipolar Disorder

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

EVEREST: Efficacy of Vasopressin Antagonism in hEart failuRE: Outcome Study With Tolvaptan

Congestive Heart Failure

United States, Canada, Netherlands, United Kingdom, France, Spain, Germany, Switzerland, Italy, Brazil, Argentina, Russian Federation, Belgium, Romania, Czech Republic, Norway, Poland, Sweden
Otsuka Pharmaceutical Development & Commercialization...
Otsuka Pharmaceutical Co., Ltd.

Completed

"SALT-2 Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia

Hyponatremia | Inappropriate ADH Syndrome | Water Intoxication | Water-electrolyte Imbalance

Germany
Kowa Research Institute, Inc.

Withdrawn

Efficacy & Long-term Safety Comparison Study of NK-104-CR & Livalo® IR With Primary Hyperlipidemia or Mixed Dyslipidemia

Dyslipidemia | Hyperlipidemia

United States
Kowa Research Institute, Inc.

Completed

A Comparison Study to Evaluate the Pharmacokinetics and Safety of NK-104-CR in Healthy Adult Volunteers

Hyperlipidemia

United States
GlaxoSmithKline

Completed

A Long-term, Safety, Tolerability, and Efficacy Study of Retigabine Immediate-release (IR) in Asian Adults With Partial Onset Seizures

Epilepsy

Thailand, Korea, Republic of, Malaysia
Lisbet Brandi

Unknown

Subacute Effect of Tolvaptan on Total Kidney Volume in Adult Patients With Autosomal Dominant Polycystic Kidney Disease (PoCKET)

Autosomal Dominant Polycystic Kidney

Denmark
Hunter Holmes Mcguire Veteran Affairs Medical Center
Otsuka America Pharmaceutical

Completed

Effect of Tolvaptan on Cognitive Function in Cirrhosis

Hepatic Encephalopathy | Cirrhosis | Hyponatremia

United States
Otsuka Beijing Research Institute
Otsuka Pharmaceutical Co., Ltd.

Completed

A Phase 2 Efficacy and Safety Study of the Tolvaptan Tablets in Patients With Non-hypovolemic Non-acute Hyponatremia

Hypovolemic Hyponatremia

China
Otsuka Pharmaceutical Development & Commercialization...

Completed

Multicenter, Randomized, Double-Blind, Placebo Controlled, Efficacy Study on the Effects of Tolvaptan on Left Ventricular Dilatation in Congestive Heart Failure Patients

Congestive Heart Failure

Canada, United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

Study to Compare the Effects of Two Dosages of Tolvaptan in Congestive Heart Failure Patients

Congestive Heart Failure

United States
Janssen Research & Development, LLC

Completed

Bioequivalence Study of Metformin Component of Canagliflozin and Metformin Fixed Dose Combination Immediate Release (IR) Tablet Comparing With Metformin IR Tablet Co-administered With Canagliflozin Tablet in Healthy Fed and Fasted Participants

Healthy

United States
GlaxoSmithKline

Completed

A 5-Period, Single Dose, Phase 1 Study in Healthy Elderly Subjects to Assess Relative Bioavailability and Food Effect of Two Oral Formulations of GSK1325756 (Free Base vs HBr Salt) and Food Effect on the HBr Formulation When Given With Omeprazole

Pulmonary Disease, Chronic Obstructive

United States

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