Clinical Trials Sponsored by Apira Science, Inc

Total 1412 results

GeneOne Life Science, Inc.

Active, not recruiting

GLS-1027 for the Prevention of Severe Pneumonitis Caused by SARS-CoV-2 Infection (COVID-19)

SARS-CoV Infection | Pneumonitis

Korea, Republic of, Puerto Rico, United States, Bulgaria, North Macedonia
SK Life Science, Inc.

Completed

A Double-Blind, Randomized, Placebo-Controlled, Phase 2 Trial of YKP3089 as Adjunctive Therapy in Subjects With Partial Onset Seizures

Partial Epilepsy

Australia, United States, Korea, Republic of, Germany, Hungary, Serbia, Bulgaria, Czechia, France, Israel, Poland, Romania, Spain, Thailand, Ukraine
SK Life Science, Inc.

Completed

Bioavailability and Food Effect Study of Cenobamate as an Oral Suspension and Tablet

Healthy

United States
SK Life Science, Inc.

Completed

A Phase 2, Multicenter, Randomized, Double-blind, Placebo Controlled Study for the Pain of Diabetic Peripheral Neuropathy

Painful Diabetic Neuropathy

United States
SK Life Science, Inc.

Completed

A Multicenter, Double-Blind, Randomized, Placebo-Controlled, 12-Week, Dose-Range-Finding Trial of YKP10811 Capsules Administered Once Daily to Subjects With Chronic Idiopathic Constipation

Chronic Idiopathic Constipation

United States
SK Life Science, Inc.

Completed

An Open-Label Extension Study to Evaluate the Safety and Tolerability of RWJ 333369 as Adjunctive Therapy in Patients 16 Years and Older With Partial Onset Seizures.

Epilepsy | Epilepsies, Partial | Epilepsy, Complex Partial | Complex Partial Seizures
SK Life Science, Inc.

Completed

An Open-Label Extension Study of the Safety and Tolerability of Carisbamate as Add-On Therapy in Patients With Partial Onset Seizures

Epilepsy, Complex Partial | Epilepsy, Partial, Motor | Epilepsy, Simple Partial | Focal Motor Epilepsy
SK Life Science, Inc.

Completed

A Study of the Effectiveness, Safety, and Tolerability of Carisbamate as Add-On Therapy in Patients With Partial Onset Seizures.

Epilepsy, Complex Partial | Epilepsy, Partial, Motor | Epilepsy, Simple Partial | Focal Motor Epilepsy
SK Life Science, Inc.

Completed

An Open-Label Extension Study to Evaluate the Safety and Effectiveness of RWJ 333369 in Patients With Epilepsy

Epilepsy | Epilepsies, Partial
Danisco
KGK Science Inc.

Completed

Probiotic Product in Healthy Adults Undergoing Antibiotic Treatment

Antibiotic Therapy

Canada
SK Life Science, Inc.

Completed

A Study of the Efficacy and Safety of RWJ-333369 as add-on Therapy in the Treatment of Partial Onset Seizures.

Epilepsy | Epilepsy, Complex Partial | Seizure Disorder | Complex Partial Seizures | Epilepsy, Focal
Sight Sciences, Inc.

Not yet recruiting

A Clinical Trial Comparing the OMNI Surgical System to Standard Medical Treatment in Pseudophakic Eyes (EVOLVE)

Primary Open Angle Glaucoma

United States
Kodiak Sciences Inc

Completed

A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared With Intravitreal Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) (DAYLIGHT)

Wet Age-related Macular Degeneration

United States, Puerto Rico
Kodiak Sciences Inc

Terminated

A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 in Participants With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy (NPDR) (GLOW)

Non-proliferative Diabetic Retinopathy

United States, Latvia, Slovakia, Poland, Puerto Rico, Spain, Czechia
Kodiak Sciences Inc

Terminated

A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME) (GLIMMER)

Diabetic Macular Edema

United States, Israel, France, Italy, Hungary, Poland, Puerto Rico, Czechia
Dermavant Sciences, Inc.

Completed

A Study to Investigate Efficacy and Safety of VTAMA (Tapinarof) Cream, 1% in Intertriginous Plaque Psoriasis

Psoriasis

United States
Sight Sciences, Inc.

Active, not recruiting

Prospective, Randomized, Masked, Controlled Trial To Evaluate The Safety And Effectiveness Of The TearCare® System In The Treatment Of The Signs And Symptoms Of Dry Eye Disease (SAHARA)

Dry Eye | Meibomian Gland Dysfunction

United States
Sight Sciences, Inc.

Terminated

Study of OMNI Surgical System and iStent for Eyes With OAG (Trident)

Glaucoma, Open-Angle

Germany, Spain, United Kingdom
Sight Sciences, Inc.

Terminated

Randomized Study of the Safety and Effectiveness of the TearCare System for the Signs and Symptoms of Dry Eye Disease

Dry Eye Syndromes

United States
Rogers Sciences Inc.

Unknown

Safety Study of a Novel Wearable Phototherapy System for the Management of Acute Burn Wounds

Burn Wound

United States
Sight Sciences, Inc.

Unknown

Use of the OMNI® Surgical System in Combination With Cataract Extraction in Open Angle Glaucoma

Open Angle Glaucoma

United States
Sight Sciences, Inc.

Terminated

Randomized Study of the Safety and Effectiveness of the Sight Sciences VISCO™360 Viscosurgical System Versus SLT in Primary Open Angle Glaucoma (VISCO360 Study)

Open-Angle Glaucoma

United States
Hapten Sciences, Inc.

Completed

A Phase I, Single-Center Study of PDC-APB in Healthy Volunteers

Contact Dermatitis

United States
MELA Sciences, Inc.

Completed

Does the Aid of MelaFind Affect Clinical Management Decisions

Melanoma

United States
5i Sciences, Inc.

Completed

Effectiveness of Continuous Negative External Pressure in Preventing Upper Airway Impairment During Routine Colonoscopy

Apnea | Airway Obstruction | Hypopnea

United States
Theraclone Sciences, Inc.

Unknown

Influenza Virus Challenge Study to Test Monoclonal Antibody TCN-032 as a Treatment for Influenza

Influenza

United Kingdom
Theraclone Sciences, Inc.

Completed

Safety Study of Anti-Influenza Virus Monoclonal Antibody to Treat Influenza

Influenza, Human

United States
MELA Sciences, Inc.

Completed

Survey Study - Sensitivity Comparison Between MelaFind and Physician Group

Melanoma
Larada Sciences, Inc.

Completed

Control of Head Lice Infestations in Children and Adults

Pediculosis

United States
Kodiak Sciences Inc

Recruiting

A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy (NPDR) (GLOW2)

Non-proliferative Diabetic Retinopathy

United States, Puerto Rico
Translational Sciences, Inc.

Recruiting

Novel α2-Antiplasmin Inactivation for Lysis of Intravascular Thrombi (NAIL-IT) Trial (NAIL-IT)

Pulmonary Embolism

United States
Kodiak Sciences Inc

Completed

A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Patients With Macular Edema Due to Retinal Vein Occlusion (RVO) (BEACON)

Macular Edema | Retinal Vein Occlusion

Spain, United States, Latvia, Israel, France, Italy, Hungary, Germany, Poland, Slovakia, Puerto Rico, Czechia
Cassava Sciences, Inc.

Enrolling by invitation

Open-label Extension for Phase 3 Clinical Trials of Simufilam

Alzheimer Disease

United States, Canada, Puerto Rico
Cassava Sciences, Inc.

Completed

Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-Simufilam Following a Single Oral Dose in Healthy Male Subjects

Metabolism | Absorption | Excretion

United States
Dermavant Sciences, Inc.

Completed

Long Term Extension Study of Tapinarof Cream, 1% for Subjects With Atopic Dermatitis

Atopic Dermatitis

United States, Canada
Cassava Sciences, Inc.

Active, not recruiting

Open-Label Extension of the PTI-125-04 Study in Mild-to-Moderate Alzheimer's Disease

Alzheimer's Disease

United States, Canada
Kodiak Sciences Inc

Terminated

A Trial to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME) (GLEAM)

Diabetic Macular Edema

United States, Latvia, Spain, Germany, Italy, Slovakia, Hungary, Puerto Rico
Dermavant Sciences, Inc.

Completed

Maximal Use Study of Tapinarof Cream, 1% in Pediatric Subjects With Extensive Atopic Dermatitis

Atopic Dermatitis

United States, Canada
Autophagy Sciences, Inc.

Completed

A Study of A4368 in Healthy Subjects (A4368)

Health Subjects

Korea, Republic of
Sight Sciences, Inc.

Terminated

A Prospective, Multicenter Study of the OMNI® Surgical System in Pseudophakic Eyes With Open Angle Glaucoma (ORION)

Glaucoma, Open-Angle

United States
Sight Sciences, Inc.

Unknown

Pilot Study of TearCare System - Long-Term Extension

Dry Eye Syndromes

United States
Rogers Sciences Inc.

Unknown

An Open Label, Phase II Trial of Continuous Low-Irradiance Photodynamic Therapy (CLIPT) Using Verteporfin (Visudyne®) for the Treatment of Cutaneous Metastases of Breast Cancer

Metastatic Breast Cancer

United States
Translational Sciences, Inc.

Unknown

Study of Safety and Biomarker Efficacy of TS23 in Healthy Volunteer (TS23Phase1a)

Myocardial Infarction | Thrombosis | Venous Thrombosis | Pulmonary Embolism | Cerebral Ischemia
Theraclone Sciences, Inc.

Completed

Safety Study of Human Anti-Cytomegalovirus Monoclonal Antibody

Cytomegalovirus Infections

United States
MELA Sciences, Inc.

Completed

Evaluation of Pigmented Skin Lesions With MelaFind(R) System

Melanoma

United States
Cassava Sciences, Inc.

Not yet recruiting

A Pharmacokinetic Study of Simufilam in Subjects With Impaired Hepatic Function

Hepatic Insufficiency
Dermavant Sciences, Inc.

Recruiting

Tapinarof for the Treatment of Plaque Psoriasis in Pediatric Subjects

Plaque Psoriasis

United States, Canada
Kodiak Sciences Inc

Terminated

Exploratory Study to Investigate the Bioactivity, Ocular and Systemic Safety, Tolerability, and Pharmacokinetics Following Single and Multiple Intravitreal Administrations of KSI-301 in Subjects With wAMD, DME and RVO

Diabetic Macular Edema | Retinal Vein Occlusion | Wet Age-related Macular Degeneration

United States
Sight Sciences, Inc.

Completed

A Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System

Glaucoma, Open-Angle

United States
Sight Sciences, Inc.

Completed

An Observational Multicenter Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System In Pseudophakic Eyes With Primary Open Angle Glaucoma (ORION 2.0)

Glaucoma, Open-Angle

United States

3

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