Clinical Trials Sponsored by Believe Big

Total 1673 results

R-Bio

Completed

Follow-up Study for Participants Jointstem Clinical Trial

Knee Osteoarthritis

Korea, Republic of
bluebird bio

Terminated

Observational Study to Evaluate Allogeneic HSCT Outcomes for Cerebral Adrenoleukodystrophy (CALD)

Cerebral Adrenoleukodystrophy (CALD) | Adrenoleukodystrophy (ALD) | X-Linked Adrenoleukodystrophy (X-ALD)

United States, United Kingdom, Argentina, Canada, Germany, Italy, Netherlands
R-Bio

Completed

Autologous Adipose Tissue Derived Mesenchymal Stem Cells Transplantation in Patient With Degenerative Arthritis

Degenerative Arthritis

Korea, Republic of
R-Bio

Completed

Clinical Trial to Evaluate Efficacy and Safety of JOINTSTEM in Patients With Degenerative Arthritis

Knee Osteoarthritis | Degenerative Arthritis

Korea, Republic of
bluebird bio

Completed

A Study Evaluating the Safety and Efficacy of the LentiGlobin BB305 Drug Product in β-Thalassemia Major Participants

β-thalassemia Major

United States, Australia, Thailand
Motif Bio

Completed

Phase 3 Study to Evaluate Safety and Efficacy of Iclaprim Versus Vancomycin for ABSSSI: REVIVE-1 (REVIVE-1)

Skin Structures and Soft Tissue Infections

United States, Bulgaria, Chile, Colombia, Germany, Latvia, Peru, Poland, Puerto Rico, Ukraine
Baudax Bio

Completed

Evaluation of N1539 Following Abdominoplasty Surgery

Pain, Post-operative

United States
R-Bio

Completed

Autologous Adipose Derived MSCs Transplantation in Patient With Spinal Cord Injury. (MSC)

Spinal Cord Injury
Rio de Janeiro State University
Eliete Bouskela

Completed

Microvascular Reactivity in Prepubertal Children (MicroChild)

Obesity | Endothelial Dysfunction | Child, Only
Rio de Janeiro State University
Eliete Bouskela

Completed

Evaluation of Heart Rate Variability and Endothelial Function Three Months After Bariatric Surgery

Obesity
Cabaletta Bio

Not yet recruiting

RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis

Systemic Sclerosis | Scleroderma

United States
ImmPACT Bio

Recruiting

A Study of IMPT-514 in Active Refractory Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus | Lupus Nephritis

United States, Australia
Cabaletta Bio

Recruiting

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

Systemic Lupus Erythematosus | Lupus Nephritis

United States
HI-Bio

Recruiting

A Study of Felzartamab in Participants With Lupus Nephritis

Lupus Nephritis

United States, Argentina, Australia
Exegenesis Bio

Recruiting

A Study of EXG102-031 in Patients With wAMD (Everest)

Neovascular (Wet) Age-related Macular Degeneration (nAMD)

United States
Cabaletta Bio

Recruiting

Open-label Study to Evaluate the Safety of Various Dosing Regimens of MuSK-CAART for MuSK Myasthenia Gravis

MuSK Myasthenia Gravis

United States
R-Bio

Not yet recruiting

Follow-up Study for Participants of Jointstem Investigator Initiated Trial by Arthroscopy

Knee Arthritis | Degenerative Arthritis
R-Bio

Not yet recruiting

Investigator Initiated Trial to Evaluate Cartilage Regeneration by Arthroscopy After JOINTSTEM Administration

Knee Arthritis | Degenerative Arthritis

Korea, Republic of
Kronos Bio

Recruiting

A Dose Escalation and Cohort Expansion Study of KB-0742 in Participants With Relapsed or Refractory Solid Tumors or Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma | Refractory Solid Tumors | Relapsed Solid Tumors

United States, Spain, United Kingdom
Akamis Bio

Recruiting

First in Human Study With NG-641, a Tumour Selective Transgene Expressing Adenoviral Vector (STAR)

Metastatic Cancer | Epithelial Tumor

United States
Endevica Bio

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of TCMCB07 in Single and Multiple Ascending Doses in Health Subjects

Cachexia

United States
bluebird bio

Enrolling by invitation

Long-term Follow-up of Subjects With Sickle Cell Disease Treated With Ex Vivo Gene Therapy

Sickle Cell Disease

United States, France
2seventy bio

Completed

Study of bb21217 in Multiple Myeloma

Multiple Myeloma

United States
Vivacelle Bio

Active, not recruiting

VBI-S for the Treatment of Hypotension in Hypovolemic Septic Shock Patients

Sepsis | Septic Shock | Hypovolemia

United States
Baudax Bio

Terminated

Safety and Pharmacokinetics of N1539 in Children 2 to <17 Years of Age Following Surgery

Post Operative Pain

United States
Mustang Bio

Terminated

Trial to Evaluate the Safety and Efficacy of MB-102 in Patients With BPDCN.

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

United States
Baudax Bio

Completed

Evaluation of Preoperative N1539 in Colorectal Surgery

Pain, Postoperative

United States
Instil Bio

Withdrawn

ITIL-168 in Advanced Solid Tumors (DELTA-2)

Cervical Cancer | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma
Akamis Bio

Completed

First in Human Study of NG-350A (an Oncolytic Adenoviral Vector Which Expresses an Anti-CD40 Antibody) (FORTITUDE)

Metastatic Cancer | Epithelial Tumor

United States
bluebird bio

Completed

A Study Evaluating the Safety and Efficacy of LentiGlobin BB305 Drug Product in β-Thalassemia Major (Also Referred to as Transfusion-dependent β-Thalassemia [TDT]) and Sickle Cell Disease

Sickle Cell Disease | Beta-Thalassemia Major

France
R-Bio

Completed

Investigator Initiated Trial to Evaluate the Efficacy and Safety of Intra-articular Injection of ADMSC Comared to Negative Control After High Tibial Osteotomy in the Osteoarthritis Patients.

Knee Osteoarthritis | Degenerative Arthritis

Korea, Republic of
BGI-Shenzhen

Completed

Calorie Restriction Intervention Induces Enterotype-associated BMI Loss in Nonobese Individuals (CRDI)

Healthy Volunteer

China
Motif Bio

Completed

Phase 3 Study to Evaluate Safety and Efficacy of Iclaprim Versus Vancomycin for ABSSSI: REVIVE-2 (REVIVE-2)

Skin Structures and Soft Tissue Infections

United States, Argentina, Belgium, Croatia, Czechia, Estonia, Hungary, Portugal, Romania, Turkey
Baudax Bio

Completed

Evaluation of N1539 Following Bunionectomy Surgery

Pain, Post-operative

United States
Baudax Bio

Completed

Placebo-Controlled Evaluation of N1539 Following Bunionectomy Surgery

Pain, Post-operative

United States
S*BIO

Completed

A Phase I Dose Escalation Study of Oral SB939 Administered Alone or With Azacitidine

Myelodysplastic Syndrome | Solid Tumors | Hematologic Malignancies

United States, Singapore
S*BIO

Completed

A Single and Multiple-Dose Study of SB1578

Healthy Volunteer

United States
Muhammad Furqan
AstraZeneca

Recruiting

Chemo-Immunotherapy Followed by Durvalumab and Ceralasertib in Treatment Naïve Patients With Extensive Stage Small Cell Lung Cancer

Extensive Stage Small Cell Lung Cancer

United States
Big Health Inc.
University of California, San Francisco

Completed

Digital CBT-I for Insomnia Disorder (CrEDIT)

Insomnia Disorder

United States
Nelson Yee
Ipsen

Active, not recruiting

Liposomal Irinotecan in Combination With Oxaliplatin, Leucovorin, and 5-fluorouracil for Patients With Locally Advanced Pancreatic Carcinoma:

Locally Advanced Pancreatic Carcinoma(LAPC)

United States
University of Illinois at Chicago
National Institute of Mental Health (NIMH); Big Brothers Big Sisters of Metropolitan...

Completed

Evaluation of a Youth Mentoring Program

Self Concept

United States
University of Illinois at Chicago
William T. Grant Foundation; Big Brothers Big Sisters of America; Herrera Consulting...

Recruiting

Culturally Smart Relationships Study (CSR)

Racism

United States
Dwight Owen
Genentech, Inc.

Recruiting

Temozolomide and Atezolizumab as Second or Third Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Extensive Stage Lung Small Cell Carcinoma | Metastatic Lung Small Cell Carcinoma | Recurrent Lung Small Cell Carcinoma

United States
John Quigley
Pfizer; AbbVie

Active, not recruiting

Study of the Safety and Efficacy of Gemtuzumab Ozogamicin (GO) and Venetoclax in Patients With Relapsed or Refractory CD33+ Acute Myeloid Leukemia:Big Ten Cancer Research Consortium BTCRC-AML17-113

Acute Myeloid Leukemia

United States
Monika Joshi, MD
AstraZeneca

Active, not recruiting

Durvalumab And Radiation Therapy Followed by Adjuvant Durvalumab in Patients With Urothelial Cancer (T2-4 N0-2 M0) of the Bladder (DUART)

Urothelial Cancer

United States
Viela Bio

Completed

A Study to Evaluate VIB7734 in Participants With Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), Sjogren's Syndrome, Systemic Sclerosis, Polymyositis, and Dermatomyositis

Systemic Lupus Erythematosus | Systemic Sclerosis | Dermatomyositis | Polymyositis | Sjogren's Syndrome | Cutaneous Lupus Erythematosus

United States, Poland, Spain
Onze Lieve Vrouw Hospital
Mayo Clinic

Terminated

Electromyography and Acceleromyography in Ventilated ICU Patients

Neuromuscular Monitoring

Belgium
Onze Lieve Vrouw Hospital
University Ghent

Completed

Individualized Cefepime Dosing Study (INCED)

Antimicrobial Treatment
Piomic Medical AG
Venenklinik Bellevue; Kantonsspital Nidwalden; Spital Männedorf

Completed

Local Application of Combined Optical and Magnetic Stimulation (COMS) for Treatment of Chronic Wounds: Safety Evaluation

Leg Ulcers Venous | Leg Ulcer Arterial | Leg Ulcer Mixed

Switzerland
Q32 Bio Inc.

Not yet recruiting

A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G

IgA Nephropathy | Lupus Nephritis (LN) | C3 (Complement Component 3) Glomerulopathy

Clinical Trials Sponsored by Believe Big

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