Clinical Trials Sponsored by University Medical Center Utrecht (UMCU)

Total 13704 results

UMC Utrecht
Erasmus Medical Center; Academisch Medisch Centrum - Universiteit van Amsterdam... and other collaborators

Unknown

Effects of Evolocumab Versus Placebo Added to Standard Lipid-lowering Therapy on Fasting and Post Fat Load Lipids in Patients With Familial Dysbetalipoproteinemia (EVOLVE-FD)

Hyperlipoproteinemia Type III | Familial Dysbetalipoproteinemia
Leiden University Medical Center
University Medical Center Groningen; UMC Utrecht; Erasmus Medical Center; Medical... and other collaborators

Recruiting

Oral Versus Intravenous Iron in IBD Patients With Anti-inflammatory Therapy. (OVI-IBD)

Inflammatory Bowel Diseases

Netherlands
Amsterdam UMC, location VUmc
University Medical Center Groningen; UMC Utrecht; Erasmus Medical Center; Academisch...

Unknown

Serial Echocardiography After Subarachnoid Hemorrhage (SEAS)

Subarachnoid Hemorrhage | Myocardial Stunning | Takotsubo Cardiomyopathy

Netherlands
Radboud University Medical Center
University Medical Center Groningen; Maastricht University Medical Center; UMC... and other collaborators

Recruiting

Personalized Elective Neck Irradiation Guided by Sentinel Lymph Node Biopsy in Larynx and Pharynx Cancer. The PRIMO Study. (PRIMO)

Oropharyngeal Squamous Cell Carcinoma | Laryngeal Squamous Cell Carcinoma | Hypopharynx Squamous Cell Carcinoma

Netherlands
Radboud University Medical Center
UMC Utrecht; Erasmus Medical Center; Academisch Medisch Centrum - Universiteit...

Completed

Pharmacokinetics of Once Daily Darunavir/Ritonavir in HIV-infected Children (DAPHNE)

Children | Human Immunodeficiency Virus

Netherlands
UMC Utrecht
University Hospital, Geneva; Universiteit Antwerpen

Completed

HOspital NEtwork STudy - Preparation for a Randomized Evaluation of Anti-Pneumonia Strategies (HONEST-PREPS)

Hospital-acquired Pneumonia | Ventilator Associated Pneumonia

France, Czechia, Serbia, Croatia, Latvia, Romania, Albania
UMC Utrecht
University of Oxford; Universiteit Antwerpen

Unknown

RESCEU Study, Defining the Burden of Disease of RSV in Older Adults

Respiratory Syncytial Virus Infections | Bronchiolitis | RSV Infection

Netherlands, Belgium, United Kingdom
The Netherlands Cancer Institute
UMC Utrecht; Fonds NutsOhra

Completed

Effects of Rapid Genetic Counseling and Testing in Newly Diagnosed Breast Cancer Patients (TIME)

Breast Neoplasms

Netherlands
UMC Utrecht
Maastricht University Medical Center; Erasmus Medical Center; Academisch Medisch... and other collaborators

Completed

SIGnificance of Routine Hysteroscopy Prior to a First 'in Vitro Fertilization'(IVF) Treatment Cycle (inSIGHT)

Intrauterine Abnormalities in Infertility

Netherlands
The Netherlands Cancer Institute
UMC Utrecht; Dutch Cancer Society

Completed

The Impact of a Web-based Patient Decision Aid for Women Considering Breast Reconstruction (TANGO)

Breast Cancer

Netherlands
Radboud University Medical Center
UMC Utrecht; Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) and other collaborators

Completed

Back-to-back Endoscopy Versus Single-pass Endoscopy and Chromoendoscopy in IBD Surveillance (HELIOS)

Colorectal Neoplasms | Inflammatory Bowel Diseases

Netherlands
The Netherlands Cancer Institute
Karolinska Institutet; Radboud University Medical Center; University Medical... and other collaborators

Recruiting

EffectiveNess of a Multimodal preHAbilitation Program in patieNts With Bladder canCEr Undergoing Cystectomy (ENHANCE)

Bladder Carcinoma

Netherlands
UMC Utrecht
Universitaire Ziekenhuizen KU Leuven; Maastricht University Medical Center; Carl...

Completed

The ADVISE Study: Advanced Visualization In Corneal Surgery Evaluation (ADVISE)

Vision Disorders | Fuchs Dystrophy | Bullous Keratopathy | Endothelial Corneal Dystrophy

Netherlands, Belgium
Netherlands Instititute for Health Services Research
Radboud University Medical Center; UMC Utrecht; Amsterdam UMC, location VUmc; Maastricht...

Unknown

The Effectiveness of Behavioral Graded Activity in Patients With Osteoarthritis of the Hip and/or Knee (GRADIT)

Osteoarthritis

Netherlands
Sanquin Research & Blood Bank Divisions
Radboud University Medical Center; Maastricht University Medical Center; UMC... and other collaborators

Unknown

Assessment of the Mu-Drop System for Serum Eye Drops (AmuSED)

Dry Eye Syndrome

Netherlands
Dr. Inge Winter
Universität Münster

Recruiting

The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. (INTENSIFY MDD)

Major Depressive Disorder | Treatment Resistant Depression

Austria, Germany, Italy, Spain, United Kingdom
Dr. Inge Winter
Universität Münster

Not yet recruiting

Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure (INTENSIFY)

Bipolar Depression | Major Depressive Disorder | Schizophrenia and Related Disorders

Israel
Academisch Medisch Centrum - Universiteit van Amsterdam...
University Medical Center Groningen; UMC Utrecht

Recruiting

Transfer of Feces in Ulcerative Colitis 2 (TURN2)

Ulcerative Colitis | Ulcerative Colitis Flare | Ulcerative Colitis Acute

Netherlands
Radboud University Medical Center
UMC Utrecht; Canisius-Wilhelmina Hospital; Gelderse Vallei Hospital; Tergooi Hospital

Completed

Pharmacokinetics of Ciprofloxacin in Critically Ill Patients (CAPOEIRA)

Bacterial Infections

Netherlands
Top Institute Pharma
GlaxoSmithKline; University Medical Center Groningen; UMC Utrecht; Academisch Ziekenhuis... and other collaborators

Unknown

Systemic Inflammation in Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

Netherlands
University of Oslo
Göteborg University; UMC Utrecht; Medical University of Lodz; Amsterdam UMC, location...

Enrolling by invitation

The Effect of Methenamine Hippurate to Reduce Antibiotic Prescribing in Elderly Women With Recurrent UTI (ImpresUWP3)

Recurrent Urinary Tract Infection

Netherlands, Norway, Poland, Sweden
UMC Utrecht
University Medical Center Groningen; Medical Center Haaglanden; Rijnstate Hospital and other collaborators

Not yet recruiting

Buccal Cancer Resection Ultrasound Guided (BRUG)

Squamous Cell Carcinoma | Buccal Mucosa Cancer
Amsterdam UMC, location VUmc
Radboud University Medical Center; University Medical Center Groningen; Maastricht... and other collaborators

Completed

Nivolumab Combined With Daratumumab With or Without Low-dose Cyclophosphamide

Myeloma

Netherlands
Top Institute Pharma
GlaxoSmithKline; AstraZeneca; University Medical Center Groningen; Maastricht University... and other collaborators

Unknown

Multiorgan Pathology in Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...
Radboud University Medical Center; University Medical Center Groningen; UMC Utrecht and other collaborators

Unknown

Comparing the Effectiveness and Costs of Bevacizumab to Ranibizumab in Patients With Retinal Vein Occlusions (BRVO) (BRVO)

Retinal Vein Occlusion

Netherlands
Erasmus Medical Center
UMC Utrecht; Albert Schweitzer Hospital; Maasstad Hospital; Medical Center Alkmaar and other collaborators

Completed

The Predictive Value of Ultrasound in Early Rheumatoid Arthritis (EVA)

Rheumatoid Arthritis | Predictive Value of Ultrasound in Early Rheumatoid Arthritis

Netherlands
St. Antonius Hospital
UMC Utrecht; Leiden University Medical Center; Medical Centre Leeuwarden; Rijnstate... and other collaborators

Completed

Ticagrelor or Prasugrel Versus Clopidogrel in Elderly Patients With an Acute Coronary Syndrome and a High Bleeding Risk: Optimization of Antiplatelet Treatment in High-risk Elderly (POPular AGE)

Unstable Angina | Non-ST-elevation Acute Coronary Syndrome | Non-ST-elevation Myocardial Infarction

Netherlands
UMC Utrecht
University of Ghana; Ghana Health Services

Unknown

Prospects for the Prevention of Pregnancy-induced Hypertension and Preeclampsia Trial (4P)

Pregnancy Induced Hypertension

Ghana
The Netherlands Cancer Institute
UMC Utrecht; Advanced Accelerator Applications

Recruiting

EBRT + Lu-PSMA for N1M0 Prostate Cancer (PROQURE-1)

Prostatic Neoplasm

Netherlands
UMC Utrecht
Radboud University Medical Center; Catharina Ziekenhuis Eindhoven; Amsterdam... and other collaborators

Not yet recruiting

Locally Advanced Pancreatic Cancer After Systemic Therapy: Ablative MR-guided Radiotherapy (LAPSTAR)

Locally Advanced Pancreatic Adenocarcinoma

Netherlands
Radboud University Medical Center
University Medical Center Groningen; UMC Utrecht; Erasmus Medical Center; Academisch... and other collaborators

Unknown

Anti-T-Lymphocyte Globulin (ATG) in Renal Transplantation of Kidneys With a Non-Heart-Beating (NHB) Donor (ATG)

Renal Transplant Patients | Recipients of a Kidney From a Non-Heart-Beating Donor

Netherlands
Radboud University Medical Center
UMC Utrecht; St. Antonius Hospital; Canisius-Wilhelmina Hospital; GGZ inGeest; ETZ

Recruiting

Prospective Assessment of Cost-effectiveness and Side-effects of Depressive Patients Treated With ECT or TCA (PROSPECT)

Depressive Disorder, Major

Netherlands
Kathelijn Fischer
Radboud University Medical Center; University Medical Center Groningen; Maastricht... and other collaborators

Recruiting

Pharmacokinetic-guided Dosing of Emicizumab (DosEmi)

Adolescent | Child | Hemophilia A With Inhibitor | Adult | Hemophilia A Without Inhibitor | Hemophilia A, Severe

Netherlands
Amsterdam UMC, location VUmc
Radboud University Medical Center; University Medical Center Groningen; UMC Utrecht and other collaborators

Recruiting

Prevention of Opioid-induced Constipation in Patients With Advanced Cancer (OMAMA)

Constipation, Opioid-Induced

Netherlands
University Medical Center Groningen
Radboud University Medical Center; Universitaire Ziekenhuizen KU Leuven; UMC... and other collaborators

Active, not recruiting

RCT Comparing Immunosuppressive Regimens in Elderly Renal Transplant Recipients (OPTIMIZE)

Elderly Patients | Immunosuppression | Renal Transplant Recipients

Netherlands, Belgium
Ludwig-Maximilians - University of Munich
Maastricht University Medical Center; UMC Utrecht; University of Oxford; University...

Terminated

Effects of Amlodipine and Other Blood Pressure Lowering Agents on Microvascular Function (TREAT-SVDs)

Cerebral Small Vessel Diseases

Netherlands, Germany, United Kingdom
Leiden University Medical Center
Radboud University Medical Center; AstraZeneca; University Medical Center Groningen and other collaborators

Active, not recruiting

Durvalumab and Olaparib in Metastatic or Recurrent Endometrial Cancer (DOMEC)

Uterine Neoplasms | Endometrial Neoplasms | Endometrium Cancer

Netherlands
UMC Utrecht
Radboud University Medical Center; University Medical Center Groningen; Maastricht... and other collaborators

Recruiting

Glioblastoma Targeted Treatment Option Maximization by WGS (GLOW)

Glioblastoma

Netherlands
Maastricht University Medical Center
Radboud University Medical Center; UMC Utrecht; Academisch Medisch Centrum -... and other collaborators

Enrolling by invitation

CORona (COVID-19) Follow Up Study: Epidemiology, Pathophysiology, Prediction, and Communication (CORFU)

COVID-19 | Long COVID | Post COVID-19 Condition

Netherlands
University Medical Center Groningen
Radboud University Medical Center; Maastricht University Medical Center; UMC... and other collaborators

Recruiting

Incidence, Course and Outcome of ABMR in Kidney Transplantation (PROCARE2)

Kidney Transplantation | Immunosuppression | Antibody-mediated Rejection

Netherlands
Radboud University Medical Center
UMC Utrecht; Rijnstate Hospital; Canisius-Wilhelmina Hospital; Gelderse Vallei... and other collaborators

Completed

Pharmacokinetics of Flucloxacillin Given by Continuous or Intermittent Infusion to ICU Patients (FANATIC)

Bacterial Infections

Netherlands
UMC Utrecht
Center for Man in Aviation, Royal Netherlands Air Force

Terminated

Screening for Coronary Artery Disease USing Primary Evaluation With Coronary CTA in Aviation Medicine (SUSPECT) (SUSPECT)

Occupational Diseases | Coronary Artery Calcification | Coronary Artery Disease (CAD) | Aviator's; Disease

Netherlands
University Medical Center Groningen
Maastricht University Medical Center; UMC Utrecht; Academisch Medisch Centrum... and other collaborators

Completed

Markers and Response to Cardiac Resynchronization Therapy (MARC)

Heart Failure

Netherlands
UMC Utrecht
Pfizer; Maastricht University Medical Center; ZonMw: The Netherlands Organisation...

Completed

Dietary Interventions in Irritable Bowel Syndrome: Soluble, Insoluble or no Fibre?

Colonic Diseases, Functional

Netherlands
Erasmus Medical Center
UMC Utrecht; Medtronic; Albert Schweitzer Hospital; Isala; University Medical Center... and other collaborators

Completed

A Trial of High and Low Pressure Level Settings on a Programmable Ventriculoperitoneal Shunt Valve for Idiopathic Normal Pressure Hydrocephalus

Idiopathic Normal Pressure Hydrocephalus

Netherlands
European Clinical Research Alliance for Infectious...
Centre Hospitalier Universitaire Dupuytren de Limoges (CHUL); Université de... and other collaborators

Recruiting

Perpetual Observational Study - Ventilator Associated Pneumonia (POS-VAP)

Ventilator Associated Pneumonia

Spain, Belgium, Serbia, Netherlands, Czechia, Germany, Greece, Albania, Romania, Croatia, France, Italy, United Kingdom
Radboud University Medical Center
University Medical Center Groningen; UMC Utrecht; Erasmus Medical Center; Amsterdam... and other collaborators

Completed

Prenatal Counseling in Extreme Prematurity: Professionals' View (PreCo-profs)

Premature Birth | Extremely Premature Infants
UMC Utrecht
The Netherlands Cancer Institute; Personal Genome Diagnostics (PGDx)

Recruiting

Circulating Tumor DNA Based Adjuvant Chemotherapy in Stage II Colon Cancer Patients: the MEDOCC-CrEATE Trial (CrEATE)

Recurrence | Circulating Tumor DNA | Colon Cancer Stage II

Netherlands
Tampere University Hospital
UMC Utrecht; Hungarian Academy of Sciences

Withdrawn

Oral Pyrophosphate Absorption in PXE Disease

Pseudoxanthoma Elasticum
Universiti Putra Malaysia
UMC Utrecht; Ministry of Health, Malaysia

Completed

Value-based Emotion-focused Educational Programme to Reduce Diabetes-related Distress (VEMOFIT)

Type 2 Diabetes Mellitus

Clinical Trials Sponsored by University Medical Center Utrecht (UMCU)

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