Search clinical trials for: Clinical research

Total 115787 results

OncoAtlas LLC
N.N. Blokhin National Medical Research Center of Oncology; Moscow MultidisciplinaryClinical...

Recruiting

Dynamics of MSI and Genomic Profile of Colorectal Cancer In the Course of Immune Checkpoint Inhibitor Therapy (BLOOMSI)

Cancer | Colorectal Cancer | Colorectal Cancer Metastatic | Colon Adenocarcinoma | MSI-H Colorectal Cancer | dMMR Colorectal Cancer

Russian Federation
Jonathan Bath
University of Missouri-Columbia

Not yet recruiting

Laser In Situ Fenestration Study (LIFE)

Aortic Aneurysm | Endovascular Aneurysm Repair
Shanghai Jiaolian Drug Research and Development...
Shanghai Pharmaceuticals Holding Co., Ltd

Not yet recruiting

A Clinical Study of B001 Injection in the Treatment of Neuromyelitis Optica Spectrum Disorders(NMOSD)

Neuromyelitis Optica Spectrum Disorders

China
Ulrich Ronellenfitsch, MD
German Federal Ministry of Education and Research; Coordinating Centre for...

Not yet recruiting

Tranexamic Acid for Reduction of Transfusion in Abdominal Surgery (TATRA)

Surgical Blood Loss | Transfusion-dependent Anemia | Abdomen Disease

Germany
Brooklyn Clinical Research

Recruiting

Triage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility (SWIFT-CORE-101)

Cardiovascular Diseases | Obesity | Metabolic Syndrome | PreDiabetes | Diabetes Type 2

United States
Axsome Therapeutics, Inc.

Recruiting

Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol (ENGAGE)

Binge-Eating Disorder

United States
Serum Institute of India Pvt. Ltd.

Recruiting

Clinical Study to Assess the Immunogenicity and Safety of Hexavalent Vaccine Containing Reduced Dose IPV

Hepatitis B Immunization | Diptheria Immunization | Tetanus Immunization | Pertussis Immunization | Haemophilus Influenzae Type B Immunization | Polio Immunization

Bangladesh, India
Yale University
ViiV Healthcare

Not yet recruiting

Pharmacist-led Intervention for Injectable HIV Treatment for Women With Health-related Social Needs

Hiv

United States
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Nimotuzumab Concurrent With Chemoradiotherapy for Patients With Unresectable Esophageal Squamous Cell Carcinoma

Esophageal Cancer | Chemotherapy | Immunotherapy | Chemoradiotherapy | Nimotuzumab

China
Cancer Institute and Hospital, Chinese Academy...

Recruiting

SHR-A1811 in Combination With Adebrelimab for the Treatment of HER2 Low-expressing Metastatic Breast Cancer

Breast Cancer

China
Novo Nordisk A/S

Recruiting

Effects of NNC0194-0499, Cagrilintide, and Semaglutide Alone or in Combinations on Liver Damage and Alcohol Use in People With Alcohol-related Liver Disease

Alcohol-related Liver Disease

Czechia, Denmark, Italy, Netherlands, Canada, Spain, United States, Australia, Japan, Greece, France, Poland, Bulgaria, Germany
Celgene

Not yet recruiting

Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis

Multiple Sclerosis, Relapsing-Remitting

United States
Bill & Melinda Gates Medical Research Institute

Not yet recruiting

Study To Evaluate Safety, Tolerability, and Pharmacokinetics of MAM01 in African Population

Healthy Volunteers

Kenya, Uganda
Boehringer Ingelheim

Recruiting

A Study in Healthy People to Compare How 2 Different Low Dose Formulations of BI 1015550 Are Taken up in the Body

Healthy

Germany
Alcon Research

Not yet recruiting

Post-market Clinical Follow-up Study of Alcon TOTAL30® Contact Lenses (Lehfilcon A)

Astigmatism | Myopia | Hyperopia | Ametropia

United States
AstraZeneca
Parexel

Recruiting

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Opioid Use Disorder

United States
Wave Life Sciences Ltd.

Recruiting

A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD (RestorAATion-2)

Alpha-1 Antitrypsin Deficiency

Canada
ETS Wound Care, LLC
Professional Education and Research Institute

Recruiting

Bioresorbable Glass Fiber Matrix in the Treatment of Diabetic Foot Ulcers (BGWM)

Diabetic Foot | Diabetic Foot Ulcer | Ulcer Foot

United States
Swiss Group for Clinical Cancer Research

Not yet recruiting

Darolutamide in Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Metastatic Castration-resistant Prostate Cancer

Switzerland
Bayer

Recruiting

A Study to Learn About How BAY 3283142 Moves Into, Through, and Out of the Body After a Single Dose in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Chronic Kidney Disease | Hepatic Impairment

United States
Tisento Therapeutics

Not yet recruiting

A Phase 2b Study of Zagociguat in Patients With MELAS (PRIZM)

Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)

United States, Australia, Italy, Germany, Canada, United Kingdom
Traws Pharma, Inc.

Recruiting

Evaluation Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of 83-0060 in Healthy Volunteers

Healthy Volunteers Only

Australia
Multitude Therapeutics Inc.

Not yet recruiting

AMT-676 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

Australia
AbbVie

Recruiting

A Study to Assess BOTOX Injections for the Change of Masseter Muscle Prominence in Adult Participants

Masseter Muscle Prominence

United States
Federal State Budgetary Institution, V. A. Almazov...

Recruiting

Prospective, Post-registration, Interventional, Randomized, in Parallel Groups, Multicenter Eurasian Clinical Study of DERIVO®/DERIVO® Mini Aneurysm Embolization Device, Europe-Asia

Intracranial Aneurysm

Russian Federation
Apnimed

Recruiting

Study That Tests AD109 in Patients Taking GLP-1 Drugs

OSA

United States
Eilean Therapeutics

Recruiting

Study of Single and Multiple Ascending Doses of ZE46-0134 in Healthy Volunteers

AML

Australia
Children's National Research Institute
Steven & Alexandra Cohen Foundation; Clinical Trials Network for Lyme and Other...

Recruiting

Navigating Pregnancy and Parenthood With Lyme Disease

Pregnancy Complications | Parenting | Tick-Borne Diseases | Lyme Disease | Chronic Lyme Disease | Tick-Borne Infections | Post Treatment Lyme Disease

United States
Sanofi Pasteur, a Sanofi Company

Recruiting

Co-administration Study of an Investigational Live-Attenuated Respiratory Syncytial Virus Vaccine in Infants and Toddlers (CORAL)

RSV Immunization

United States, Puerto Rico
Imperial College London

Not yet recruiting

Identifying Wearable Biomarkers to Monitor Dietary Intake (FoodSense)

Healthy Volunteers | Blood Glucose | Wearables | Metabolism | Energy Intake | Digestion | Dietary Intake Assessment

United Kingdom
Brazilian Clinical Research Institute
Alliança Diagnostic

Not yet recruiting

Anti-inflammatory and Anti-thrombotic Therapy With colcHicine and Low Dose Rivaroxaban for Major Adverse Cardiovascular Events Reduction in Ischemic Stroke (ARCHIMEDES)

Ischemic Stroke
Mahidol University
Health Systems Research Institute; The Heart Association of Thailand

Not yet recruiting

COhort of antithrOmbotic Use and cLinical Outcomes in Patients With Atrial Fibrillation (COOL-AF) Phase 2

Atrial Fibrillation

Thailand
Summit Therapeutics
Akeso

Recruiting

Phase III Study of AK112 for NSCLC Patients

Non-Squamous Non-small Cell Lung Cancer

Canada, United States, Spain, Italy, France, United Kingdom
Institute of Cancer Research, United Kingdom
Case45 Ltd

Not yet recruiting

Deployment and Clinical Evaluation of an AI-powered Digital Oncology Biomarker Tool to guidE Treatment in TNBC (AIDOBE)

Triple Negative Breast Cancer
Ann & Robert H Lurie Children's Hospital of Chicago
Northwestern University; University of Chicago; Loyola University Chicago; Central...

Not yet recruiting

Early Detection of Infection Using the Fitbit in Pediatric Surgical Patients (i-DETECT)

Appendicitis | Appendicitis Acute | Appendectomy

United States
The Children's Hospital of Zhejiang University...
Leman Biotech Co., Ltd

Recruiting

Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Relapsed and/or Refractory CD19-positive B Cell Hematological Malignancies Clinical Research

Acute Lymphoblastic Leukemia | Non-hodgkin Lymphoma

China
Humanitas Clinical and Research Center
European Society of Intensive Care Medicine

Not yet recruiting

Fluid Challenge in Intensive Care The FENICE II Study (FENICE II)

Critical Illness | Septic Shock

Italy
Fudan University

Recruiting

A Clinical Research About CD70-targeted CAR-NKT Cells Therapy Advanced Malignant Solid Tumors

Solid Tumor

China
University of California, San Diego

Recruiting

The Effects and Mechanisms of a High CBD Cannabis Extract (BRC-002) for the Treatment of Pain and Health in Complex Regional Pain Syndrome

Complex Regional Pain Syndrome

United States
Pelage Pharmaceuticals, Inc.

Recruiting

Safety, Pharmacokinetics and Efficacy of PP405 in Adults With AGA

Androgenetic Alopecia

United States
mAbxience Research S.L.

Recruiting

A Study Investigating the Safety, Absorption, and Elimination of MB04, a New Compound That May Potentially be Used in the Treatment of Autoimmune Disorders (MB04-A-01-23)

Healthy Volunteers

Netherlands
Seattle Institute for Biomedical and Clinical Research
Patient-Centered Outcomes Research Institute

Not yet recruiting

Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention (FOCuSEd)

Chronic Obstructive Pulmonary Disease | Obstructive Sleep Apnea | Overweight and Obesity

United States
Scipher Medicine

Recruiting

PREDICT Therapy Selection for JAK, T-cell, or IL-6 Inhibitor Therapies Using a Molecular Signature Response Classifier (PREDICT) (PREDICT)

Rheumatoid Arthritis

United States
Tasso Inc.

Recruiting

A Multi-site Clinical Evaluation of Capillary Blood Samples Collected Using the Tasso+SST Device for Downstream Analyte Testing

Serum Analytes

United States
RenJi Hospital
Zhujiang Hospital; Clinical Research Institute, Shanghai Jiao Tong University...

Not yet recruiting

Study on the Efficacy of Long-term Drainage of Subdural Effusion After Decompressive Craniectomy

Traumatic Brain Injury | Subdural Effusion | Decompressive Craniectomy

China
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1, Open-label Study Evaluating the Pharmacokinetics and Drug-drug Interaction of VX-993 in Healthy Adults

Pain

United Kingdom
AstraZeneca

Recruiting

Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Balcinrenone

Hepatic Impairment

United States
Novo Nordisk A/S

Not yet recruiting

A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose Weight

Obesity

United Kingdom, Germany, Canada, United States, France
AbbVie

Recruiting

A Study to Assess BOTOX Injections in Adult Participants for the Change of Masseter Muscle Prominence

Masseter Muscle Prominence

United States
Assembly Biosciences

Not yet recruiting

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5366 in Healthy Participants and Participants Seropositive for HSV-2 With Recurrent Genital Herpes

Recurrent Genital Herpes Simplex Type 2

New Zealand

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