Search clinical trials for: Leukine

Total 187 results

National Cancer Institute (NCI)

Completed

Vaccine Therapy With PROSTVAC/TRICOM and Flutamide Versus Flutamide Alone to Treat Prostate Cancer

Prostate Cancer

United States
St. Jude Children's Research Hospital
CURE Childhood Cancer, Inc.

Completed

Combination Chemotherapy, Monoclonal Antibody, and Natural Killer Cells in Treating Young Patients With Recurrent or Refractory Neuroblastoma

Neuroblastoma

United States
M.D. Anderson Cancer Center
Bayer

Completed

Rituximab Plus Sargramostim (GM-CSF) In Patients With Chronic Lymphocytic Leukemia

Leukemia

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI); Susan G. Komen Breast Cancer Foundation

Completed

Vaccine Therapy, Trastuzumab, and Vinorelbine in Treating Patients With Locally Recurrent or Metastatic Breast Cancer

Breast Cancer

United States
M.D. Anderson Cancer Center
The Vaccine Company

Terminated

Proteinase 3 PR1 Peptide Mixed With Montanide ISA-51 VG Adjuvant and Administered With GM-CSF and PEG-INTRON(R)

Leukemia

United States
Immatics Biotechnologies GmbH
BioNTech SE; University Hospital Tuebingen; BCN Peptides; EU-funded GAPVAC Consortium

Completed

GAPVAC Phase I Trial in Newly Diagnosed Glioblastoma Patients

Glioblastoma

Spain, Switzerland, Denmark, Germany, Netherlands
Edward Nelson

Completed

Administration as a Biological Adjuvant in Clinically-Staged, Resectable Pancreatic Adenocarcinoma

Pancreatic Cancer | Resectable Pancreatic Adenocarcinoma

United States
M.D. Anderson Cancer Center

Terminated

Trial of ID-Specific Donor Vaccinated Lymphocyte Infusion for Patients With Myeloma Relapsing or Failing to Achieve a Complete Remission After an Allogenic Transplant

Myeloma

United States
University of Leeds
Yorkshire Cancer Research

Withdrawn

REO13 Melanoma With of Without GM-CSF

Melanoma | Cancer of Skin
John P. Fruehauf
Bayer

Completed

Docetaxel and Vinorelbine Plus Sargramostim in Metastatic Malignant Melanoma

Metastatic Melanoma

United States
Providence Health & Services
Providence Cancer Center, Earle A. Chiles Research Institute; Robert W. Franz...

Completed

Immunochemoradiotherapy in Patients With Pancreatic Cancer

Locally Advanced Pancreatic Adenocarcinoma

United States
Newcastle-upon-Tyne Hospitals NHS Trust
Medical Research Council; Newcastle University

Completed

Does GM-CSF Restore Neutrophil Phagocytosis in Critical Illness? (GMCSF)

Sepsis | Critical Illness | Immuno-suppression

United Kingdom
Massachusetts General Hospital
Bayer; Dana-Farber Cancer Institute; Beth Israel Deaconess Medical Center; Brigham...

Terminated

CHOP-Rituximab Augmented With GM-CSF in Patients With Previously Untreated Diffuse Large B Cell Non-Hodgkin's Lymphoma

Lymphoma, B-Cell | Lymphoma, Non-Hodgkin | Lymphoma, Diffuse

United States
Celldex Therapeutics

Completed

Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma (ACT IV)

Glioblastoma | Gliosarcoma | Small Cell Glioblastoma | Giant Cell Glioblastoma | Glioblastoma With Oligodendroglial Component

United States, Canada, Australia, Israel, Taiwan, United Kingdom, Belgium, France, Spain, Germany, Austria, Brazil, Colombia, Czechia, Greece, Hungary, India, Italy, Mexico, Netherlands, New Zealand, Peru, Switzerland, Thailand
Celldex Therapeutics

Completed

Phase II Study of Rindopepimut (CDX-110) in Patients With Glioblastoma Multiforme (ACT III)

Malignant Glioma

United States
St. Jude Children's Research Hospital

Completed

A Pilot Study of Immunotherapy Including Haploidentical NK Cell Infusion Following CD133+ Positively-Selected Autologous Hematopoietic Stem Cells in Children With High Risk Solid Tumors or Lymphomas

Lymphoma | Neuroblastoma | High-risk Tumor

United States
Stanford University
Bayer

Terminated

Phase II GM-CSF Plus Mitoxantrone in Hormone Refractory Prostate Cancer

Prostatic Neoplasms

United States
Immatics Biotechnologies GmbH

Completed

IMA901 in Patients Receiving Sunitinib for Advanced/Metastatic Renal Cell Carcinoma

Metastatic Renal Cell Carcinoma

United States, France, Romania, United Kingdom, Italy, Russian Federation, Poland, Germany, Hungary, Netherlands, Norway
University of Washington
National Cancer Institute (NCI)

Completed

Sargramostim and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer That Did Not Respond to Previous Chemotherapy

Fallopian Tube Cancer | Peritoneal Cavity Cancer | Ovarian Clear Cell Cystadenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Serous Cystadenocarcinoma | Stage IV Ovarian Epithelial Cancer | Brenner Tumor | Recurrent Ovarian Epithelial Cancer | Stage III Ovarian Epithelial Cancer | Ovarian Mucinous... and other conditions

United States
National Cancer Institute (NCI)

Completed

MS-275 and GM-CSF in Treating Patients With Myelodysplastic Syndrome and/or Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphocytic Leukemia

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy and Peripheral Blood Stem Cell Transplant Followed By Aldesleukin and Sargramostim in Treating Patients With Inflammatory Stage IIIB or Metastatic Stage IV Breast Cancer

Inflammatory Breast Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IIIB Breast Cancer | Estrogen Receptor-negative Breast Cancer | Estrogen Receptor-positive Breast Cancer | Progesterone Receptor-negative Breast Cancer | Progesterone Receptor-positive Breast Cancer

United States
UbiVac
National Cancer Institute (NCI); Mayo Clinic; Louisiana State University Health... and other collaborators

Completed

Combination Vaccine Immunotherapy (DRibbles) for Patients With Definitively-Treated Stage III Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States
Washington University School of Medicine

Completed

Plerixafor and Sargramostim (GM-CSF) for Mobilization of Allogeneic Sibling Donors

Lymphoma, Non-Hodgkin | Myelodysplastic Syndromes | Leukemia, Myeloid, Acute | Multiple Myeloma | Hodgkin Disease | Leukemia, Lymphocytic, Chronic, B-Cell

United States
University of Washington
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Stage IV Breast Cancer

HER2-positive Breast Cancer | Male Breast Cancer | Stage IV Breast Cancer | Recurrent Breast Cancer

United States
Massachusetts General Hospital
Bayer; Dana-Farber Cancer Institute

Completed

GM-CSF, Sargramostim in Women With Recurrent Ovarian Cancer

Ovarian Cancer | Fallopian Tube Cancer
Sanofi

Withdrawn

Open Label Study of Sargramostim Among Patients Receiving Myelosuppressive Induction Chemotherapy for Acute Myelogenous Leukemia

Acute Myeloid Leukemia NOS
Sanofi
National Institute on Aging (NIA)

Withdrawn

Safety Study of Sargramostim in Treating Patients With Mild Cognitive Impairment Due to Alzheimer's Disease

Dementia Alzheimer's Type

United States
Bionor Immuno AS
Celgene Corporation

Completed

Vacc-4x + Lenalidomide vs. Vacc-4x +Placebo in HIV-1-infected Subjects on Antiretroviral Therapy (ART) (IMID)

HIV-1 Infection

Germany
Bionor Immuno AS
Celgene Corporation

Completed

Safety and Efficacy of Romidepsin and the Therapeutic Vaccine Vacc-4x for Reduction of the Latent HIV-1 Reservoir (REDUC)

HIV I Infection

Denmark
Galena Biopharma, Inc.

Completed

Efficacy and Safety Study of NeuVax™ (Nelipepimut-S or E75) Vaccine to Prevent Breast Cancer Recurrence (PRESENT)

Breast Cancer With Low to Intermediate HER2 Expression

United States, United Kingdom, France, Israel, Germany, Canada, Russian Federation, Romania, Bulgaria, Czech Republic, Hungary, Poland, Ukraine
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

Vaccine Therapy and Sargramostim in Treating Patients With Malignant Glioma

Glioblastoma | Gliosarcoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Giant Cell Glioblastoma | Recurrent Brain Neoplasm | Mixed Glioma

United States
Emory University
Bayer

Completed

Immunotherapy for Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), Blast Phase Chronic Myelogenous Leukemia (BP CML), and Myelodysplastic Syndrome (MDS) Relapse After Allogeneic Transplantation

Leukemia

United States
Beth Israel Deaconess Medical Center
Bayer

Completed

Nonmyeloablative Allogeneic Stem Cell Transplantation From HLA-Matched Unrelated Donor for the Treatment of Hematologic Disorders

Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | AML | Myelodysplastic Syndrome | Aplastic Anemia | Myeloproliferative Disorder | CLL | ALL

United States
BioVex Limited
Amgen

Completed

Efficacy and Safety Study of Talimogene Laherparepvec Compared to Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) in Melanoma

Melanoma

United States, United Kingdom, Canada, South Africa
M.D. Anderson Cancer Center
Novartis

Completed

High-Dose Gleevec Alone or in Combination With Peg-Intron and GM-CSF in Early Phase Chronic Myelogenous Leukemia (CML)

Leukemia, Myeloid, Chronic

United States
Benovus Bio, Inc.

Unknown

Phase I Study of an Oncofetal Antigen Multi-Peptide Immunotherapy in Subjects With Hematologic Cancer (BBMPI03)

Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML) | Multiple Myeloma (MM) | Smoldering Multiple Myeloma (sMM)

United States
The Methodist Hospital Research Institute
Bayer

Terminated

Trial of GM-CSF Given in Combination With Ketoconazole and Mitoxantrone in Patients With Progressive Prostate Cancer

Prostatic Neoplasms

United States
The Methodist Hospital Research Institute
Bayer

Terminated

Safety and Efficacy Study of GM-CSF, Thalidomide Plus Docetaxel in Prostate Cancer

Prostatic Neoplasms

United States
The Methodist Hospital Research Institute
Oxford BioMedica

Completed

Activity of TroVax® Alone vs. TroVax® Plus GM-CSF in Patients With Prostate Cancer

Prostatic Neoplasms

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Activated T-cell Therapy, Low-Dose Aldesleukin, and Sargramostim in Treating Patients With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer That is Stage III-IV, Refractory, or Recurrent

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Malignant Ovarian Clear Cell Tumor | Stage IIIA Fallopian Tube Cancer | Stage IIIA Ovarian Cancer | Stage IIIA Primary Peritoneal Cancer | Stage IIIB Fallopian Tube Cancer | Stage IIIB Ovarian... and other conditions
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Biological Therapy in Treating Women With Stage IV Breast Cancer

Breast Cancer

United States
M.D. Anderson Cancer Center
Bayer

Completed

FCR Plus Sargramostim (GM-CSF) as Frontline Therapy for Symptomatic Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

United States
M.D. Anderson Cancer Center
Genentech, Inc.

Completed

Rituximab + GM-CSF in Patients With Follicular B-Cell Lymphoma

Lymphoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Autologous Stem Cell Transplants for Chronic Myelogenous Leukemia

Leukemia

United States
National Cancer Institute (NCI)

Completed

A Phase II Study of PROSTVAC-V (Vaccinia)/TRICOM and PROSTVAC-F (Fowlpox)/TRICOM With GM-CSF in Patients With PSA Progression After Local Therapy for Prostate Cancer

Recurrent Prostate Carcinoma | Stage I Prostate Cancer | Stage III Prostate Cancer | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
University of Kentucky
Bayer

Withdrawn

Randomized Phase 2 Trial of Pre-chemotherapy Leukine vs. Leukine-Dexamethasone in Combination With Gemzar & 5-FU in Patients With Metastatic Renal Cell Carcinoma

Renal Cell Carcinoma
National Cancer Institute (NCI)

Completed

Vaccine Therapy, GM-CSF, and Interferon Alfa-2b in Treating Patients With Locally Advanced or Metastatic Cancer That Expresses Carcinoembryonic Antigen (CEA)

Adult Solid Neoplasm

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Inhaled Sargramostim in Treating Patients With First Pulmonary (Lung) Recurrence of Osteosarcoma

Sarcoma | Metastatic Cancer

United States, Canada, Australia, Puerto Rico
Emory University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Granulocyte-Macrophage Stimulating Factor in the Treatment of Peripheral Arterial Disease (GPAD-2)

Peripheral Arterial Disease

United States
M.D. Anderson Cancer Center

Terminated

Doxorubicin With Cisplatin, High-Dose Methotrexate, and Additional Risk-Adapted Outpatient Chemotherapy

Osteosarcoma

United States

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