Search clinical trials for: QT Interval

Total 2181 results

Asklepios Neurological Clinic Bad Salzhausen
University of Giessen

Completed

Cortisone and QTc-Interval

QTc-interval

Germany
Zydus Therapeutics Inc.

Completed

A Study to Evaluate the Effect of Saroglitazar Magnesium on the QTc Interval in Healthy Volunteers

Healthy

India
Bayer
Merck Sharp & Dohme LLC

Completed

Study to Evaluate the QT / QTc Interval Prolongation Potential of Vericiguat

Coronary Artery Disease

Germany, Moldova, Republic of, Netherlands
David Grant U.S. Air Force Medical Center

Completed

Post-Exercise Cardiovascular Responses Following Energy Drink Consumption

QTc Interval

United States
Northeast Iowa Medical Education Foundation

Completed

Pharmacist Use of ECG to Inform Drug Therapy Decisions for Patients Receiving QT Prolonging Medications

Torsades de Pointes | Qt Interval, Variation in | Torsades de Pointe Caused by Drug (Disorder)

United States
David Grant U.S. Air Force Medical Center

Terminated

Evaluation of Energy Drinks on Electrocardiographic, Vascular and Hematologic Parameters in Healthy Volunteers

Cardiovascular Diseases

United States
Spero Therapeutics
Celerion

Completed

A Single-Dose, Randomized, Placebo- and Active-Control, Four-Way, Cross-Over Study for the Evaluation of the Effect of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) on the QT/QTc Intervals in Adult Healthy Subjects

TQT Study

United States
Janssen Research & Development, LLC

Completed

A Study to Investigate the Effect of JNJ-64565111 on Cardiac Repolarization (Corrected QT Interval) Compared With Placebo in Healthy Adults: a Thorough ECG Study Employing Placebo, JNJ-64565111, and a Positive Control (Moxifloxacin)

Healthy

United States
Cara Therapeutics, Inc.

Completed

Study to Investigate the Effects of Single Intravenous Doses of Difelikefalin (CR845) on the QTc Interval in Healthy Subjects

Healthy

United States
AstraZeneca
Parexel

Completed

A Study to Investigate the Effect of Single Dose of AZD6094 (600 mg) on Cardiac Repolarization in Healthy Volunteers

Solid Tumors

United States
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

CiPA Phase 1 ECG Biomarker Validation Study

Pharmacokinetics | Pharmacodynamics | Drug-induced QT Prolongation

United States
NorthSea Therapeutics B.V.

Completed

A Study to Evaluate the Effects of NST-4016 on QT/Corrected QT (QTc) Interval

Dyslipidemias

United Kingdom
Celgene

Completed

A Phase I Study to Assess the Safety, Pharmacokinetics, and Potential Effects of Amrubicin on the QT/QTc Interval in Cancer Patients With Advanced Solid Tumors.

Advanced Solid Tumors

United States
Pfizer

Completed

A Study To Determine The Effect Of Single-dose PF-04965842 On QTc Interval In Healthy Volunteers Compared With Placebo and Moxifloxacin

Healthy Volunteers

Belgium
University of the Pacific

Completed

The Effect of Energy Drink on Cardiovascular Variables: A Randomized Controlled Trial

Cardiovascular Diseases

United States
NorthShore University HealthSystem

Unknown

Effect of Methadone and Hydromorphone on the QT Interval After Anesthesia and Surgery

EKG-QT Prolongation

United States
Entasis Therapeutics

Completed

Study Evaluating the Effect of ETX2514 on Cardiac Repolarization in Healthy Male or Female Volunteers

Acinetobacter Baumannii-calcoaceticus Complex Infections

United States
Indiana University
American Heart Association; Purdue University

Completed

Influence of Testosterone Administration on Drug-Induced QT Interval Prolongation and Torsades de Pointes

Long QT Syndrome

United States
Mitsubishi Tanabe Pharma Corporation

Completed

A Study to Evaluate the Effect of MCI-186 at Therapeutic and Supra-Therapeutic Doses on the QT Interval(QT)/Corrected QT Interval(QTc) Interval in Healthy Subjects

Healthy Adult Subjects

Japan
Daiichi Sankyo, Inc.

Completed

The Effect of CS-3150 Exposure on Corrected QT (QTc) Interval Duration in Healthy Volunteers

Hypertension | Mineralocorticoid Receptor Antagonist

United States
University of Wisconsin, Madison
National Heart, Lung, and Blood Institute (NHLBI); Medical College of Wisconsin and other collaborators

Completed

Fetal and Neonatal Magnetophysiology

Long QT Syndrome | Fetal Arrhythmia | Abnormality in Fetal Heart Rate or Rhythm

United States
Tel-Aviv Sourasky Medical Center
Tel Aviv Medical Center

Completed

Effect of Grapefruit on QT Interval in Healthy Volunteers and Patients With Congenital Long QT Syndrome

Long QT Syndrome

Israel
Grünenthal GmbH

Completed

Effect of a Multiple-dose Oral Administration of CG5503 PR on the Electrical Activity of the Heart in 48 Healthy Men and Women

Prolonged QTc Interval | Pharmacokinetic

Germany
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Effect of MK-8669 (Ridaforolimus) on QTc Interval in Participants With Advanced Cancer (MK-8669-037)

Metastatic or Locally Advanced Cancer
Duzce University

Completed

The Effect of Anesthetic Agents Management on ECG Changes of Patients Who Were Operated Under RIVA

Qt Interval, Variation in

Turkey
AstraZeneca
Quintiles, Inc.

Completed

Effects of AZD1775 on the PK Substrates for CYP3A, CYP2C19, CYP1A2 and on QT Interval in Patients With Advanced Cancer

Solid Tumours

United States
Yonsei University

Completed

The Effect of Deliberate Hypotension on QTc, Tp-e Intervals and Heart Rate Variability

Mandibular Retrognathism | Mandibular Prognathism

Korea, Republic of
Medicines Development for Global Health

Completed

Effect of a Single Oral Dose of Moxidectin on the Cardiac QT Interval of Healthy Volunteers

QT Effects in Healthy Volunteers

United States
Pfizer

Completed

A Study to Evaluate the PF-06700841 Effect on QTc Interval in Healthy Volunteers

Healthy

Belgium
Yonsei University

Completed

The Effects of Dexmedetomidine and Tracheal Intubation on Heart Rate Variability and QTc Interval

Anesthesia, General

Korea, Republic of
Herlev and Gentofte Hospital

Completed

Exploring Mechanisms and Morphology of QT Interval Prolongation (TriQarr)

Sudden Cardiac Death | Long Qt Syndrome 1-2

Denmark
Daiichi Sankyo, Inc.
Medpace, Inc.

Completed

Effect of Tivantinib on the QTC Interval in Cancer Subjects

Solid Tumors

United States
Yonsei University

Completed

The Comparison of Changes of QTc, Tp-e Interval, and Tp-e/QT Ratio, Tp-e/QTc Ratio on the ECG During Robotic-assisted Laparoscopic Radical Prostatectomy Under Sevoflurane, Desflurane and Total Intravenous Anesthesia -Randomized Controlled Trial

Robotic-assisted Laparoscopic Radical Prostatectomy

Korea, Republic of
Cassiopea SpA

Completed

A Study to Investigate the Effects of Cortexolone 17α-propionate (and Its Metabolites) on Healthy Volunteers' Heart

Healthy Volunteers

United Kingdom
Samsung Medical Center

Completed

Clinical Study to Evaluate Effect on QT/QTc Interval After Multiple Dose of Celecoxib

Qt Interval, Variation in

Korea, Republic of
Copenhagen University Hospital at Herlev

Unknown

Drug-induced Repolarization ECG Changes

Depression | Pathologic Processes | Heart Diseases | Cardiovascular Diseases | Congenital Abnormalities | Death | Death, Sudden | Arrhythmias, Cardiac | ADHD | Heart Arrest | Heart Defects, Congenital | Cardiovascular Abnormalities | Genetic Disease | Death, Sudden, Cardiac | Psychiatric Disorder | Genetic Syndrome | Long... and other conditions

Denmark
Pfizer

Completed

A Study To Evaluate The Effect Of PF-04447943 On Qtc Interval In Healthy Adult Subjects

Healthy

United States
University of California, San Francisco

Terminated

The Relation of GnRH Treatment to QTc Interval in Transgender Females

Gender Dysphoria

United States
Akebia Therapeutics

Completed

Effect of AKB-6548 on Cardiac Repolarization Intervals in Healthy Volunteers

Healthy Volunteers

United States
Janssen Scientific Affairs, LLC
Bausch Health Americas, Inc.; Cipher Pharmaceuticals Inc.

Completed

Study to Evaluate the Effects of Tramadol Hydrochloride on Cardiac Repolarization in Healthy Participants

Healthy

United States
Universiti Sains Malaysia

Completed

KCNH2 Polymorphisms on the QTc Interval in Kelantanese Malays Patients Receiving Methadone Maintenance Therapy (MMT)

Opioid Dependence | Methadone Toxicity | HERG Gene Mutation

Malaysia
Nobelpharma

Completed

Investigation of Arrhythmogenic Effect of NPC-15 (NPC-15-7)

Qt Interval, Variation in

Japan
Wockhardt

Completed

Evaluate the Effect of WCK 5222 on the QT/QTc Interval in Healthy Volunteers

QT/QTc Interval in Healthy Volunteers

United States
Konkuk University Medical Center

Completed

Ramosetron Pre-treatment for PONV and QT Prolongation

PONV | Prolonged QTc Interval

Korea, Republic of
Royal Prince Alfred Hospital, Sydney, Australia
Merck Sharp & Dohme LLC

Completed

QT Interval Abnormalities in Sulfonylurea Treated Type 2 Diabetes: Relationship to Treatment Induced Hypoglycaemia

Diabetes Related Complications
Tel-Aviv Sourasky Medical Center

Completed

Abnormal QT-Response to the Sudden Tachycardia Provoked by Standing in Individuals With Drug-induced Long QT Syndrome

Long QT Syndrome

Israel
Gilead Sciences

Terminated

Effect of Eleclazine on Shortening of the QT Interval, Safety, and Tolerability in Adults With Long QT Syndrome Type 3

Long QT Syndrome Type 3

United States, Germany, Canada, Netherlands, Italy, France, Israel, United Kingdom
Emory University
Children's Healthcare of Atlanta

Terminated

Low-dose Epinephrine Infusion Tests in Adolescent and Pediatric Patients (LEAP)

Congenital Disorders

United States
TaiGen Biotechnology Co., Ltd.

Completed

A Study Evaluating the Effect of a Single-dose Oral Administration of Nemonoxacin Capsule on QTc Intervals and Heart Rhythms of Healthy Subjects and the Influence of Food Intake on QTc Intervals and Pharmacokinetic Characteristics

Healthy Volunteers
Galera Therapeutics, Inc.
Syneos Health

Completed

A Phase 1, Randomized, Placebo-and Positive-Controlled Crossover Study to Determine the Effect of Single-Dose GC4419 on QTc Interval in Healthy Volunteers

Healthy | Healthy Volunteers

Australia

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