Search clinical trials for: Sickel Cell Anemia

Total 52257 results

Shanghai BDgene Co., Ltd.
Ruijin Hospital

Recruiting

Safety and Efficacy of Gene Modified Autologous Hematopoietic Stem Cells to Treat Transfusion-dependent β-thalassemia

β-thalassemia Major

China
Shanghai BDgene Co., Ltd.
Shanghai Children's Medical Center

Recruiting

Safety and Efficacy of Gene Modified Autologous Hematopoietic Stem Cells to Treat Transfusion-dependent Beta-thalassemia

β-thalassemia

China
First Affiliated Hospital of Guangxi Medical University
Genmedicn Biopharma Ltd.

Recruiting

A Study Evaluating the Safety and Efficacy of LentiRed Drug Product in Transfusion-dependent β-Thalassemia [TDT]

Transfusion Dependent Beta-Thalassemia

China
First Affiliated Hospital of Guangxi Medical University
Genmedicn Biopharma Ltd.

Recruiting

A Study Evaluating the Safety and Efficacy of the GMCN-508A Drug Product in Transfusion-dependent α-Thalassemia Participants

Transfusion-dependent α-Thalassemia

China
University of Alabama at Birmingham

Recruiting

Study on Use of Omega-3 Fatty Acids to Improve Outcomes in Individuals With Sickle Cell Disease

Sickle Cell Disease

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

A Reduced-Intensity Conditioning Regimen (Cyclophosphamide, Pentostatin, Anti-thymocyte Globulin) Followed by Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Patients With Refractory or Recurrent Severe Aplastic Anemia

Recurrent Severe Aplastic Anemia | Refractory Severe Aplastic Anemia

United States
The University of The West Indies

Recruiting

Arterial Function Parameters and Transcranial Doppler Velocity in Paediatric Patients With Sickle Cell Disease (AFAT)

Sickle Cell Disease

Jamaica
Shenzhen Hemogen

Recruiting

Safety and Efficacy Evaluation of β-globin Restored Autologous Hematopoietic Stem Cells in β-thalassemia Major Patients

β-thalassemia

China
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)

Sickle Cell Disease | Thalassemia | Thalassemia, Beta

United States
University of Aberdeen

Not yet recruiting

ORCHARD- Optimising Home Assessment of Rural Patients (ORCHARD)

Cancer | Sickle Cell Disease | Immunosuppression | Inborn Errors of Metabolism | Organ Transplant | COPD Asthma
University of Pennsylvania

Recruiting

Effects of the Contraceptive Implant in Women With Sickle Cell Disease (SCD CURE)

Sickle Cell Disease

United States
Forma Therapeutics, Inc.
Emory University

Not yet recruiting

Study of the Effect of Etavopivat on Cerebral Hemodynamic Response in Children With Sickle Cell Disease

Sickle Cell Disease

United States
Duke University
National Institutes of Health (NIH)

Recruiting

Gerofit Exercise Intervention for Older Adults With Sickle Cell Disease (SICKLE-FIT Study) (SICKLE-FIT)

Sickle Cell Disease

United States
University Hospital, Lille
University Hospital, Rouen; Centre Hospitalier Universitaire Dijon; University... and other collaborators

Recruiting

Individualized or Conventional Transfusion Strategies During Peripheral VA-ECMO (ICONE)

Anemia | Extracorporeal Membrane Oxygenation | Cardiogenic Shock | Transfusion Related Complication | Oxygen Delivery

France
Gruppo Italiano Malattie EMatologiche dell'Adulto

Recruiting

Ibrutinib for the Treatment of AIHA in Patients With CLL/SLL or CLL-like MBL

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma | Autoimmune Hemolytic Anemia | Monoclonal B-Cell Lymphocytosis CLL-Type

Italy
Centre Hospitalier Universitaire de Liege
Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators

Recruiting

Baby Detect : Genomic Newborn Screening

Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions

Belgium
National Cancer Institute (NCI)

Recruiting

Defining the Natural History of Squamous Cell Carcinoma in Fanconi Anemia

Fanconi Anemia | Inherited Bone Marrow Failure Syndrome

United States
University of Cape Town
University of Stellenbosch; University of KwaZulu

Recruiting

South African Paediatric Surgical Outcomes Study 2 (SAPSOS2)

Iron Deficiency Anemia | Anaemia | Iron | Prospective Studies | Paediatric Surgery | Interventional Studies

South Africa
Wuhan Union Hospital, China
Wuhan TongJi Hospital; Wuhan Central Hospital

Not yet recruiting

Umbilical Cord Derived Mesenchymal Stem Cells for Treatment-induced Myelosuppression in Hematologic Malignancies

Infections | Hematologic Neoplasms | Anemia | Bleeding | Thrombocytopenia | Neutropenia

China
Children's Hospital Medical Center, Cincinnati
Jinja Regional Referral Hospital (JRRH), Sickle Cell Clinic, Jinja, Uganda

Recruiting

Alternative Dosing And Prevention of Transfusions (ADAPT)

Sickle Cell Disease

Uganda
GlaxoSmithKline

Recruiting

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Oral GSK4172239D Compared With Placebo in Sickle Cell Disease Participants Aged 18 to 50 Years

Hematologic Diseases | Anaemia, Sickle Cell

United States
Novartis Pharmaceuticals

Recruiting

A Study of Efficacy and Safety of Ianalumab in Previously Treated Patients With Warm Autoimmune Hemolytic Anemia (VAYHIA)

Warm Autoimmune Hemolytic Anemia (wAIHA)

China, Japan, Spain, Singapore, France, Germany, Taiwan, United States, Italy, India, Malaysia, Argentina, Hungary, Israel, Australia, Thailand, United Kingdom, Romania
University Hospital, Toulouse

Recruiting

Inflammation, Platelets and Sickle Cell Disease (Il-Padre)

Sickle Cell Disease | Platelet Activation | Thromboinflammation

France
University of Chicago

Recruiting

Tocilizumab for Acute Chest Syndrome

Sickle Cell Disease | Acute Chest Syndrome

United States
Sanguine Biosciences

Recruiting

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Heart Diseases | Stroke | Lymphoma | Multiple Sclerosis | Kidney Diseases | Diabetes | Leukemia | Age-Related Macular Degeneration | Cancer | Arthritis | Schizophrenia | Thyroid Diseases | Parkinson Disease | Hepatitis | Vasculitis | Psoriasis | Asthma | Amyloidosis | Fibromyalgia | Graves Disease | Alzheimer Disease | Celiac Disease | Cirr... and other conditions

United States
Pfizer
Pfizer

Recruiting

GBT021601-022: A Study of GBT021601 in Participants With Sickle Cell Disease (SCD)

Sickle Cell Disease

United States, Nigeria
Angde Biotech Pharmaceutical Co., Ltd.

Recruiting

A Study of PEG-EPO Injection (CHO Cells) for Maintenance Therapy of Patients With Renal Anemia .

Renal Anemia

China
Washington University School of Medicine
Biogen; BioLineRx, Ltd.

Recruiting

Motixafortide and Natalizumab to Mobilize CD34+ Hematopoietic Stem Cells for Gene Therapies in Sickle Cell Disease (SCD)

Sickle Cell Disease

United States
Hospital Clinic of Barcelona
Institut d'Investigacions Biomèdiques August Pi i Sunyer; Banc de Sang i Teixits

Recruiting

Red Blood Cells From Umbilical Cord for Transfusion of Preterm Infants

Infant, Extremely Premature | Erythrocyte Transfusion | Umbilical Cord Issue

Spain
University of Chicago

Recruiting

Preoperative PRRT Versus Surgical Cytoreduction in Metastatic Pancreatic Neuroendocrine Tumors to the Liver

Pancreas Cancer | Pancreatic Neuroendocrine Tumor

United States
University of Cincinnati

Not yet recruiting

Minocycline In Neurocognitive Outcomes - Sickle Cell Disease (MINO-SCD)

Cognitive Impairment | Cognitive Dysfunction | Cognitive Change | Sickle Cell Disease | Cognitive Decline | Cognitive Deficit | Neuroinflammatory Response

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Exploring Near Infrared Spectroscopy (NIRS) Technologies for Assessment of Muscle Physiology, Tissue Oxygenation, and Blood Flow in Patients With Sickle Cell Disease (SCD)

SCD

United States
Boston Children's Hospital
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Recruiting

A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202) (TransIT)

Severe Aplastic Anemia

United States
St. Jude Children's Research Hospital

Recruiting

Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PET

Sickle Cell Disease

United States
Bristol-Myers Squibb

Recruiting

A Study to Evaluate Luspatercept (ACE-536) in Chinese Participants Who Require Regular Red Blood Cell Transfusions Due to Beta (β)-Thalassemia.

Beta-thalassemia

China
Dr. Marjon H. Cnossen MD PhD
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Recruiting

Brain Structure and Neurocognitive Development in Sickle Cell Disease; a Longitudinal Cohort Study (BRICK Study) (BRICK)

Sickle Cell Disease | Brain Development Abnormality

Netherlands
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Efficacy of the antiCD38 Monoclonal Antibody Isatuximab in the Treatment of PCRA by Major ABO Mismatch After Allogeneic Hematopoietic Stem Cell Transplantation (ErythroSIM)

Immunological Pure Red Cell Aplasia
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

In Vitro Effect Study of Interleukin-2 Muteins on Regulatory T Cells of Patients With Different Autoimmune, Allo-immune or Inflammatory Diseases (MuTreg)

Multiple Sclerosis | Autoimmune Diseases | Rheumatoid Arthritis | Systemic Lupus Erythematosus | Atopic Dermatitis | Vitiligo | Alopecia | Autoimmune Thyroiditis | Inflammatory Disease | Acquired Bone Marrow Aplasia | Gvhd
University Hospital, Grenoble

Not yet recruiting

Nano-rheological Biomarkers for Patients With Sickle Cell Disease (SCD) Versus Control Subjects (Other Constitutional Red Blood Cell Diseases and Healthy Subjects) (DREPNANO)

Sickle Cell Disease
Cairo University

Recruiting

Pilates Physical Activity in Sickle Cell Disease

Sickle Cell Disease

Egypt
The First Affiliated Hospital of Soochow University

Recruiting

GVHD Prophylaxis by Addition of CD20 Monoclonal Antibody to the Conditioning Regimen in SAA With Treatment of Allo-HSCT

Aplastic Anemia

China
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Using Fostamatinib to Treat Post-Hematopoietic Stem Cell Transplant Immune-mediated Cytopenias

Immune Mediated Anemia | Immune Mediated Thrombocytopenia | Chronic GVHD

United States
Vertex Pharmaceuticals Incorporated
CRISPR Therapeutics

Recruiting

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

Hematologic Diseases | Genetic Diseases, Inborn | Sickle Cell Disease | Hemoglobinopathies | Sickle Cell Anemia | Thalassemia | Beta-Thalassemia

United States, Italy, Germany, Saudi Arabia
Tanta University

Recruiting

L-Arginine in Children Having Sickle Cell Disease With Increased Tricuspid Regurgitant Jet Velocity

Sickle Cell Disease

Egypt
Children's Hospital Los Angeles
Novartis

Not yet recruiting

Crizanlizumab Improves Tissue Oxygen Supply Demand Matching in Patients With Sickle Cell Anemia (SEG101)

Sickle Cell Disease
National Cancer Institute (NCI)

Recruiting

Feasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adults With Sickle Cell Disease (SCD)

Insomnia | Sickle Cell Disease | Sickle Cell Anemia | Sleeplessness | Transient Insomnia | Nonorganic Insomnia | Chronic Insomnia

United States
Beam Therapeutics Inc.

Recruiting

BEACON: A Study Evaluating the Safety and Efficacy of BEAM-101 in Patients With Severe Sickle Cell Disease (BEACON)

Sickle Cell Disease

United States
Julia Xu
Carnegie Mellon University; American Society of Hematology

Recruiting

Hydroxyurea and EPO in Sickle Cell Disease (ACHiEvE-SCD)

Sickle Cell Disease | Anemia, Sickle Cell

United States, Nigeria
Editas Medicine, Inc.

Recruiting

EDIT-301 for Autologous Hematopoietic Stem Cell Transplant (HSCT) in Participants With Transfusion-Dependent Beta Thalassemia (TDT)

Hemoglobinopathies | Thalassemia Major | Thalassemia Intermedia | Transfusion Dependent Beta Thalassemia

United States, Canada
Barau Dikko Teaching Hospital

Recruiting

Primary Prevention of Stroke in Children With Sickle Cell Anaemia in Nigeria in the Community (SPRING-COM)

Stroke | Sickle Cell Disease

Nigeria

Search clinical trials for: Sickel Cell Anemia

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in South Africa

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations