Search clinical trials for: Therapeutic vaccine

Total 22010 results

SQZ Biotechnologies

Terminated

Study of SQZ-eAPC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors

Adult Solid Tumor

United States
TuHURA Biosciences, Inc.
Dana-Farber Cancer Institute; University of Southern California; H. Lee Moffitt... and other collaborators

Active, not recruiting

Immunotherapy With IFx-Hu2.0 Vaccine for Advanced Non-melanoma Skin Cancers

Merkel Cell Carcinoma | Cutaneous Squamous Cell Carcinoma | Non-Melanoma Skin Cancers

United States
CHA Vaccine Institute Co., Ltd.

Completed

A Study to Evaluate the Efficacy and Safety of Therapeutic Hepatitis B Vaccine

Hepatitis B, Chronic

Korea, Republic of
Shenzhen Immuno Cure Biomedical Company Limited
Shenzhen Third People's Hospital

Active, not recruiting

ICVAX as a HIV Therapeutic DNA Vaccine

Human Immunodeficiency Virus | Human Immunodeficiency Virus I Infection

China
Speransa Therapeutics

Terminated

A Study Assessing the Safety, Tolerability, Immunogenicity of COVID-19 Vaccine Candidate PRIME-2-CoV_Beta, Orf Virus Expressing SARS-CoV_2 Spike and Nucleocapsid Proteins

SARS-CoV-2 Infection

United States, Germany
Craig L Slingluff, Jr
Celldex Therapeutics

Completed

Vaccination With 6MHP, With or Without Systemic CDX-1127, in Patients With Stage II-IV Melanoma (Mel-65)

Melanoma

United States
ModernaTX, Inc.

Completed

A Study of mRNA-1010 Seasonal Influenza Vaccine in Adults 50 Years Old and Older

Seasonal Influenza

Spain, United States, Denmark, Poland, United Kingdom, Germany, Canada, Taiwan, Bulgaria, Netherlands, Estonia
OSE Immunotherapeutics

Terminated

OSE2101 Versus Chemotherapy in HLA-A2 Positive Patients With Advanced NSCLC After Immune Checkpoint Inhibitor Failure (ATALANTE-1)

Non Small Cell Lung Cancer

France, Spain, Israel, United States, United Kingdom, Italy, Poland, Czechia, Germany, Hungary
Amal Therapeutics
Boehringer Ingelheim

Active, not recruiting

Phase 1b Study to Evaluate ATP128, VSV-GP128 and BI 754091, in Patients With Stage IV Colorectal Cancer (KISIMA-01)

Metastatic Colorectal Cancer | Colorectal Cancer | Liver Metastasis Colon Cancer | Stage IV Colon Cancer | Stage IV Rectal Cancer | MSS

United States, Belgium, Switzerland, Germany
Merck Sharp & Dohme LLC

Completed

V160 2-Dose and 3-Dose Regimens in Healthy Cytomegalovirus (CMV) Seronegative Females (V160-002)

Cytomegalovirus (CMV) Infections

United States, Australia, Canada, Finland, Israel, Russian Federation, Spain
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

Trial to Evaluate the Safety and Immunogenicity of a Modified Vaccinia Ankara (MVA)-Based Anti-Cytomegalovirus (CMV) Vaccine (Triplex®)

HIV Infections | Cytomegalovirus Infections | Vaccine

United States
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers

Healthy Volunteers (Meningococcal Infection)

United States, Puerto Rico
University of Florida
Immunomic Therapeutics, Inc.

Terminated

RENEW: Feasibility of CMV RNA-Pulsed Dendritic Cells Vaccines for the Treatment of Newly Diagnosed Glioblastoma Patients.

Glioblastoma

United States
ModernaTX, Inc.

Active, not recruiting

A Study to Evaluate the Safety and Immunogenicity of mRNA-1975 and mRNA-1982 Against Lyme Disease in Participants 18 Through 70 Years of Age

Lyme Disease

United States
Novavax
Department of Health and Human Services

Completed

A Study to Evaluate the Efficacy, Immune Response, and Safety of a COVID-19 Vaccine in Adults ≥ 18 Years With a Pediatric Expansion in Adolescents (12 to<18 Years) at Risk for SARS-CoV-2

Covid19 | SARS-CoV Infection

United States, Mexico, Puerto Rico
Enterome
Covance

Active, not recruiting

First-in-Human, Phase 1b/2a Trial of a Multipeptide Therapeutic Vaccine in Patients With Progressive Glioblastoma (ROSALIE)

Glioblastoma, Adult

United States, Spain, France, Germany
University of Campinas, Brazil
Conselho Nacional de Desenvolvimento Científico e Tecnológico; Paulínia Municipal...

Completed

COVID-19: BCG As Therapeutic Vaccine, Transmission Limitation, and Immunoglobulin Enhancement (BATTLE)

COVID-19 | SARS-CoV 2 | Transmission | BCG | Therapeutic Vaccine

Brazil
Enterome

Active, not recruiting

A Novel Therapeutic Vaccine (EO2401) in Metastatic Adrenocortical Carcinoma, or Malignant Pheochromocytoma/Paraganglioma (Spencer)

Pheochromocytoma | Paraganglioma | Adrenocortical Carcinoma

United States, France, Spain, Denmark, Sweden, Germany, Italy, Netherlands
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Specialized Immune Cells (nCTLs) and a Vaccine (Alpha-type-1 Polarized Dendritic Cells) in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Stage III Fallopian Tube Cancer AJCC v8 | Stage III Ovarian Cancer AJCC v8 | Stage III Primary Peritoneal Cancer AJCC v8 | Stage IIIA Fallopian Tube Cancer AJCC v8 | Stage IIIA Ovarian Cancer AJCC v8 | Stage IIIA Primary Peritoneal Cancer AJCC v8 | Stage IIIA1 Fallopian Tube Cancer AJCC v8 | Stage... and other conditions

United States
CHA Vaccine Institute Co., Ltd.

Completed

A Study to Evaluate the Safety and Efficacy of Therapeutic Hepatitis B Vaccine

Hepatitis B, Chronic

Korea, Republic of
BioNTech SE

Completed

Safety and Immunogenicity of RNA-based Vaccines Against SARS-CoV-2 Variants in Healthy Participants

COVID-19 | SARS-CoV2 Infection | SARS-CoV-2 Acute Respiratory Disease | SARS (Disease)

United States, Germany, Turkey, South Africa
Sharon Riddler
National Institute of Allergy and Infectious Diseases (NIAID)

Active, not recruiting

Comparison of Dendritic Cell-Based Therapeutic Vaccine Strategies for HIV Functional Cure (DC-HIV04)

HIV Infections

United States
Vinbiocare Biotechnology Joint Stock Company
Arcturus Therapeutics, Inc.

Completed

The ARCT-154 Self-Amplifying RNA Vaccine Efficacy Study (ARCT-154-01) (ARCT-154-01)

COVID-19 Vaccines

Vietnam
Craig L Slingluff, Jr
Celldex Therapeutics

Active, not recruiting

Melanoma Vaccine Against Neoantigen and Shared Antigens by CD40 Activation and TLR Agonists In Patients With Melanoma (Including Ocular Melanoma) (Mel66)

Melanoma | Ocular Melanoma | Uveal Melanoma

United States
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator...

Active, not recruiting

Early Phase Clinical Trial About Therapeutic Biological Product Mix for Treating HPV (9vHPV-BCG)

HPV Infection

United States
BriaCell Therapeutics Corporation
LumaBridge

Enrolling by invitation

Combination Study of SV-BR-1-GM With Retifanlimab

Breast Cancer | Breast Neoplasm | Metastatic Breast Cancer | Breast Cancer Metastatic

United States
Lisata Therapeutics, Inc.

Terminated

Vaccine Therapy in Treating Patients With Kidney Cancer

Kidney Cancer

United States
Hubro Therapeutics AS
Quotient Sciences

Completed

Safety and Immune Response to FMPV-1

Colorectal Cancer

United Kingdom
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Vaccine Therapy With or Without Imiquimod in Treating Patients With Grade 3 Cervical Intraepithelial Neoplasia

Cervical Cancer | Precancerous Condition | HPV Disease | Human Papilomavirus

United States
Candel Therapeutics, Inc.
University of Pennsylvania

Completed

Intrapleural AdV-tk Therapy in Patients With Malignant Pleural Effusion (MpeTK01)

Breast Cancer | Ovarian Cancer | Lung Cancer | Mesothelioma | Malignant Pleural Effusion

United States
Candel Therapeutics, Inc.

Completed

Phase 1b Study of AdV-tk + Valacyclovir Combined With Radiation Therapy for Malignant Gliomas (BrTK01)

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma

United States
Candel Therapeutics, Inc.

Completed

AdV-tk Therapy With Surgery and Chemoradiation for Pancreas Cancer (PaTK01) (PaTK01)

Pancreatic Cancer | Pancreatic Adenocarcinoma

United States
Pfizer

Completed

A Trial to Describe the Immunogenicity and Safety of 2 Doses of Bivalent rLP2086 (Trumenba) and a Pentavalent Meningococcal Vaccine in Healthy Subjects >=10 to <26 Years of Age.

Meningococcal Vaccine

United States, Finland, Czechia, Poland
University Hospital, Grenoble
Commissariat A L'energie Atomique

Completed

Immune Responses to COVID-19; Isolation of Neutralizing Antibodies for Therapeutics and Vaccine. (AcNT-COVID19)

SARS-CoV 2

France
National Institute of Allergy and Infectious Diseases...

Completed

A Study of SARS CoV-2 Infection and Potential Transmission in Individuals Immunized With Moderna COVID-19 Vaccine (CoVPN 3006)

SARS-CoV-2 Infection

United States
Merck Sharp & Dohme LLC

Completed

Safety, Tolerability, and Immunogenicity of V114 in Healthy Infants (V114-029) (PNEU-PED)

Pneumococcal Infections | Pneumococcal Vaccines

United States, Puerto Rico, Thailand, Turkey
Regeneron Pharmaceuticals

Completed

A Trial to Learn if a COVID-19 Therapeutic is Safe and Well Tolerated, and How it Works in the Body of Healthy Adult Participants

Healthy

Belgium
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Eli Lilly and Company; AstraZeneca; AIDS Clinical Trials... and other collaborators

Completed

ACTIV-2: A Study for Outpatients With COVID-19

Covid19 | Coronavirus

United States, Argentina, Brazil, Guatemala, Mexico, Philippines, Puerto Rico, South Africa, Canada
Aelix Therapeutics
Gilead Sciences

Completed

Safety, Tolerability and Immunogenicity of MVA.HTI and ChAdOx1.HTI With Vesatolimod in HIV-1 Positive Patients (AELIX-003)

HIV/AIDS

Spain
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); AIDS Clinical... and other collaborators

Active, not recruiting

Analytical Treatment Interruption (ATI) to Assess the Immune System's Ability to Control HIV in Participants Who Became HIV-infected During the HVTN 704/HPTN 085 AMP Study

HIV Infection

United States, Peru, Brazil
Steven Deeks
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

Therapeutic Vaccination in Treated HIV Disease

HIV-1-infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

SARS-CoV-2 Immune Responses After COVID-19 Therapy and Subsequent Vaccine

Covid19 | SARS-CoV2 Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

ACTIV-5 / Big Effect Trial (BET-A) for the Treatment of COVID-19

COVID-19

United States
Pfizer
Valneva Austria GmbH

Completed

Alternative Schedule Study For VLA15, a Vaccine Candidate Against Lyme Borreliosis

Lyme Borreliosis

United States
University of British Columbia
Ministry of Health, British Columbia

Completed

Evaluation of Therapeutic Initiative's Cystitis Portrait and Therapeutics Letter

Quality Improvement | Clinical Audit

Canada
Pfizer

Completed

MenABCWY Noninferiority Study in Healthy Participants ≥10 to <26 Years of Age

Meningococcal Vaccine

United States, Denmark, Hungary, Czechia, Poland
SQZ Biotechnologies

Completed

Study of SQZ-PBMC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors

Adult Solid Tumor

United States, Canada, Germany
Providence Therapeutics Holdings Inc.

Completed

PTX-COVID19-B, an mRNA Humoral Vaccine, Intended for Prevention of COVID-19 in a General Population. This Study is Designed to Demonstrate the Safety, Tolerability, and Immunogenicity of PTX-COVID19-B in Comparison to the Pfizer-BioNTech COVID-19 Vaccine.

Covid19 Vaccine

Canada, South Africa
Insight Therapeutics, LLC
Brown University; Seqirus

Completed

Adjuvanted Influenza Vaccination Year 2 Follow-On Survey

Influenza | Influenza, Human | Influenza-like Illness

United States
Insight Therapeutics, LLC
Brown University; Sanofi Pasteur, a Sanofi Company; Case Western Reserve University

Active, not recruiting

Recombinant Influenza Vaccination in U.S. Nursing Homes

Influenza | Influenza, Human | Influenza -Like Illness

United States

Search clinical trials for: Therapeutic vaccine

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