Search clinical trials for: nucleoside

Total 262 results

Seng Gee Lim
Singapore General Hospital; Tan Tock Seng Hospital; Changi General Hospital

Unknown

Halting Nucleoside Analogues in Chronic Hepatitis B (HALT-NUCS)

Chronic Hepatitis B

Singapore
Seng Gee Lim
Merck Sharp & Dohme LLC; Singapore General Hospital; Tan Tock Seng Hospital; Changi... and other collaborators

Completed

Efficacy of Switching or Adding Pegylated Interferon in Chronic Hepatitis B Patients on Long Term Oral Antiviral Therapy (SWAP)

Chronic Hepatitis B

Singapore
Kirby Institute
Merck Sharp & Dohme LLC; amfAR, The Foundation for AIDS Research; Abbott

Completed

A Trial of 2 Options for Second Line Combination Antiretroviral Therapy Following Virological Failure of a Standard Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI)+2N(t)RTI First Line Regimen (SECOND-LINE)

HIV Infections

Taiwan, Australia, Argentina, Singapore, India, France, South Africa, Chile, Germany, Hong Kong, Ireland, Malaysia, Mexico, New Zealand, Nigeria, Peru, United Kingdom
AHS Cancer Control Alberta
Cross Cancer Institute

Terminated

An Imaging Study of [18]F-fluoro-3'-Deoxy-3'-L-fluorothymidine ([18]F-FLT) in Patients With Locally Advanced or Metastatic Pancreatic Cancer Who Will be Treated With Gemcitabine or Other Nucleoside Analogs

Pancreatic Cancer

Canada
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Total-Body Irradiation Followed By Cyclosporine and Mycophenolate Mofetil in Treating Patients With Severe Combined Immunodeficiency Undergoing Donor Bone Marrow Transplant

Severe Combined Immunodeficiency | Adenosine Deaminase Deficiency | Immune System Disorder | Autosomal Recessive Disorder | Purine-Nucleoside Phosphorylase Deficiency | Severe Combined Immunodeficiency With Absence of T and B Cells | X-Linked Severe Combined Immunodeficiency

United States
Beijing Ditan Hospital

Unknown

Cohort Study of Clinical Outcomes in Chronic HBV Infection Patients With Low HBsAg Under Unplanned Intervention

Chronic Hepatitis B Infection

China
UConn Health
United States Department of Defense

Terminated

Circulating Adenosine Levels Before and After Intravenous (IV) Persantine

Ischemia | Coronary Disease

United States
Seng Gee Lim
National Medical Research Council (NMRC), Singapore; Singapore Clinical Research...

Unknown

Tenofovir Versus Tenofovir + Telbivudine for Chronic Hepatitis B (DUAL)

Chronic Hepatitis B

Singapore
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp... and other collaborators

Completed

A5288/MULTI-OCTAVE: Management Using Latest Technologies to Optimize Combination Therapy After Viral Failure (MULTI-OCTAVE)

HIV-1 Infection

Kenya, Brazil, South Africa, Uganda, Zimbabwe, India, Malawi, Haiti, Thailand, Peru
Clovis Oncology, Inc.

Completed

Study to Evaluate Efficacy of CO-1.01 as Second Line Therapy for Gemcitabine-Refractory Stage IV Pancreatic Adenocarcinoma

Metastatic Pancreatic Adenocarcinoma

United States
Third Affiliated Hospital, Sun Yat-Sen University
Peking University; First People's Hospital of Foshan; Shenzhen Third People's...

Unknown

The Optimizing Treatment of PegIFN Alfa in HBeAg-negative CHB Patients With Low Level HBsAg

Chronic Hepatitis B

China
Third Affiliated Hospital, Sun Yat-Sen University
Wuhan Union Hospital, China

Unknown

The Optimizing Treatment of Peginterferon Alpha in Chronic Hepatitis B Patients With Low Level HBsAg

Chronic Hepatitis B

China
University of California, San Francisco
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

HIV Protease Inhibitors for the Prevention of Malaria in Ugandan Children (PROMOTE-PEDS)

HIV Infections | Malaria

Uganda
University Hospital, Tours
University Hospital, Rouen; Central Hospital, Nancy, France; Poitiers University... and other collaborators

Completed

Trial to Evaluate the Interest of a Reductive Anti Retroviral Strategy Using Dual Therapy Inspite of Triple Therapy (TRULIGHT)

HIV

France
M.D. Anderson Cancer Center

Completed

A Study Of Deoxycoformycin(DCF)/Pentostatin In Lymphoid Malignancies

Chronic Lymphocytic Leukemia | Cutaneous T-cell Lymphoma | Peripheral T-cell Lymphoma

United States
M.D. Anderson Cancer Center
Chiron Corporation

Completed

Phase I Study of Continuous Infusion Schedule of FMdC in Hematologic Malignancies

Hematologic Malignancies

United States
Qin Ning

Unknown

A Prospective,Observational Follow-up Study of Nucleoside Treated Patients With Chronic Hepatitis B (OCEAN Study)

Hepatitis B, Chronic

China
GlaxoSmithKline

Completed

Study To Evaluate Long Term Maintenance With TRIZIVIR After Boosted Protease Inhibitor (PI) Or Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) In HIV-1 Infected Adults

HIV Infections
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Determining the Effects of Observed and Self-Administered Drug Regimens in HIV Infected Adults

HIV Infections

Peru, Brazil, South Africa, Uganda, Botswana, Haiti, Zambia, Zimbabwe
Asociacion para el Estudio de las Enfermedades...
Merck Sharp & Dohme LLC

Completed

Bitherapy With the Combination of Raltegravir and Darunavir (BIRDi) (BIRDi)

HIV/AIDS | Comorbidities

Spain
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Evaluating Pharmacokinetic Interactions With Vaginal Ring Contraceptives and ART

HIV-1 Infection

United States, Peru, Puerto Rico, Brazil, Botswana, Kenya, South Africa, Thailand
Tongji Hospital

Unknown

A Real-World Study of Pegylated Interferon In Nucleoside-treated Patients With Chronic Hepatitis B (COST)

Chronic Hepatitis B

China
King Abdullah International Medical Research Center
Hoffmann-La Roche

Unknown

To Study the Effect of Adding on Pegylated Interferon (PEG-INF) Therapy for Patients Diagnosed With Chronic Hepatitis B (RC14/055)

Hepatitis B

Saudi Arabia
Roxane Laboratories

Completed

Bioequivalency Study of Torsemide Tablets Under Fasting Conditions

Edema

United States
ViiV Healthcare
GlaxoSmithKline

Completed

Dolutegravir Compared to Darunavir/Ritonavir , Each in Combination With Dual Nucleoside Reverse Transcriptase Inhibitors (NRTIs) in ART-naive Subjects (FLAMINGO)

Infection, Human Immunodeficiency Virus

Spain, France, Germany, United States, Italy, Romania, Russian Federation, Switzerland, Puerto Rico
Sidney Kimmel Cancer Center at Thomas Jefferson...
National Institutes of Health (NIH)

Terminated

Positron Emission Tomography Imaging Using Copper Cu 64 TP3805 in Patients With Breast Cancer

Breast Carcinoma
ContraVir Pharmaceuticals, Inc.

Terminated

A Comparative Study of FV-100 vs. Valacyclovir for the Prevention of Post-Herpetic Neuralgia

Herpes Zoster | Postherpetic Neuralgia | Shingles

United States
Janssen-Cilag International NV

Completed

A Clinical Trial Comparing the Efficacy of Darunavir/Ritonavir Monotherapy Versus a Triple Combination Therapy Containing Darunavir/Ritonavir and 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Patients With Undetectable Plasma HIV-1 RNA on Current Treatment (PROTEA)

Human Immunodeficiency Virus (HIV) Infections | Acquired Immunodeficiency Syndrome (AIDS) Virus

France, United Kingdom, Belgium, Germany, Spain, Switzerland, Denmark, Israel, Austria, Poland, Hungary, Sweden, Ireland
Qin Ning

Unknown

Sequential/Combination Therapy in Nucleoside or Nucleotide Analogue (NA)-Suppressed Chronic Hepatitis B Patients (NPGV)

Chronic Hepatitis b
SYZ Cell Therapy Co..
Sun Yat-sen University; Fujian Cancer Hospital; Beijing 302 Hospital; Nanfang Hospital... and other collaborators

Suspended

Multiple Antigen Specific Cell Therapy (MASCT) for Hepatocellular Carcinoma(HCC) Patients After Radical Resection or Radio Frequency Ablation(RFA). (HCC DC CTL)

Hepatocellular Carcinoma

China
Community Research Initiative of New England
Bristol-Myers Squibb; Merck Sharp & Dohme LLC

Completed

BATAR: Individuals Currently Taking Boosted Atazanavir as Part of an HIV Treatment Regimen Will be Evaluated to See if Substituting Raltegravir for Nucleoside Transcriptase Inhibitors Will be Safe and Well Tolerated. (BATAR)

HIV

United States
Beijing Ditan Hospital

Unknown

The Changes of Cytokines During Antiviral Therapy

Chronic Hepatitis B Infection

China
Beijing Ditan Hospital

Unknown

The Changes of Treg Cells Frequency and Function During Antiviral Therapy

Chronic Hepatitis B Infection

China
Beijing Ditan Hospital

Unknown

The Changes of Natural Killer Cells Frequency and Function During Antiviral Therapy

Chronic Hepatitis B Infection

China
Beijing Ditan Hospital

Unknown

The Changes of CD8+T Cells Frequency and Function During Antiviral Therapy

Chronic Hepatitis B Infection

China
Yao Xie

Unknown

The Changes of CD4+T Cells Frequency and Function During Antiviral Therapy

Chronic Hepatitis B Infection

China
National Institutes of Health Clinical Center (CC)

Completed

Effect of Genetics on Metabolism of Efavirenz

Metabolism

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Immunologic Effects of Supplemental Monosaccharide and Nucleoside Derivatives in Patients With Inherited Disorders of Glycosylation

PGM3

United States
Onconova Therapeutics, Inc.

Completed

Safety of 24-hour Infusion of ON 01910.Na in Combination With Gemcitabine in Advanced Solid Tumors

Solid Tumor

United States
Hoffmann-La Roche

Terminated

A 48 Week Study Comparing Treatment With Saquinavir + Lopinavir/Ritonavir in Combination With Enfuvirtide HAART Versus Saquinavir + Lopinavir/Ritonavir + Other Nucleoside Combinations to See the Efficacy of These Treatments in Patients Infected With HIV-1

HIV Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

Effectiveness of Nucleoside Supplementation or Switch to Tenofovir in Reversing Fat Loss in HIV Infected Adults

Metabolic Diseases | HIV Infections | Nutrition Disorders | Lipodystrophy

United States
University of California, Davis

Completed

A Pilot Project of Virologic, Pharmacologic and Immunologic Correlates of Gastrointestinal-Associated Lymphoid Tissue Immune Reconstitution Following Maraviroc Therapy

HIV Infections

United States
AbbVie (prior sponsor, Abbott)
Veeda Clinical Research

Completed

Study on the Usage, Dosing, Tolerability, and Effectiveness of Kaletra Tablet

Human Immunodeficiency Virus
AbbVie (prior sponsor, Abbott)

Completed

Kaletra in Combination With Antiretroviral Agents (PROTEKT)

Human Immunodeficiency Virus
Therapeutic Concepts

Completed

Nucleoside Switch Pilot for Virologically Controlled HIV Subjects With Decreasing CD4 Cells Who Have Received TDF-based ARV Therapy (EPZSwitch)

HiV1- Positive

United States
Gilead Sciences

Completed

Registry Study for Patients With Chronic HBV Receiving Nucleotide Therapy

Hepatitis B

United States, Canada
Merck Sharp & Dohme LLC

Terminated

Quality of Life of HIV-infected Participants Switched to Raltegravir Versus Other Antiretroviral Regimens (MK-0518-266)

Human Immunodeficiency Virus
Hoffmann-La Roche

Completed

A Study to Collect Blood Biomarker Samples From Participants With Chronic Hepatitis B (CHB) Who Received Treatment With Pegasys (Peginterferon Alfa-2a) ± Nucleoside/Nucleotide Analogue

Hepatitis B, Chronic

Thailand, China, Italy, United Kingdom, Korea, Republic of, Taiwan, Austria, Bulgaria, Germany, New Zealand, France, Poland, Portugal, Romania, Greece
National Institute of Allergy and Infectious Diseases...

Completed

Observational Study of Fat Loss in HIV Infected Adults Taking Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

Metabolic Diseases | HIV Infections | Nutrition Disorders | Lipodystrophy

United States
Institut National de la Santé Et de la Recherche...

Completed

"Cancersensor": Circadian Rhythms

Metastatic Colorectal Cancer

France

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