Search clinical trials for: oral therapeutic

Total 29176 results

United Therapeutics

Terminated

Open-Label Study of Oral Treprostinil in Digital Ulcers (DISTOL-EXT)

Systemic Sclerosis

United States, Canada, United Kingdom
Nabriva Therapeutics AG

Completed

Study to Assess the Safety and PK of Oral and IV Xenleta in Adults With Cystic Fibrosis

Cystic Fibrosis

United States
SpringWorks Therapeutics, Inc.

Active, not recruiting

Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF) (DeFi)

Desmoid Tumor | Aggressive Fibromatosis

United States, Belgium, Germany, Canada, Italy, Netherlands, United Kingdom
CHUV chirurgie orale et maxillofaciale

Completed

Lateral Arm Free Flap: a Useful Flap in the Maxillo-facial Surgeon's Therapeutic Armory, Case Series

Reconstructive Surgery

Switzerland
Rennes University Hospital

Terminated

Oral Therapeutic Education in Stimulated Parkinsonian Patients (BUCCO-PARK)

Parkinson Disease | Oral Infection

France
Memorial Sloan Kettering Cancer Center
Y-mAbs Therapeutics

Active, not recruiting

Bivalent Vaccine With Escalating Doses of the Immunological Adjuvant OPT-821, in Combination With Oral β-glucan for High-Risk Neuroblastoma

Neuroblastoma

United States
Phoenix Molecular Designs

Active, not recruiting

Phase 1/1b/2 Study of Oral PMD-026 in Patients With Metastatic Breast Cancer (Dauntless-1)

Metastatic Breast Cancer

United States
MitoImmune Therapeutics

Active, not recruiting

Evaluate the Safety and Efficacy for Oral Mucositis Prevention of MIT-001 in Auto HSCT (Capella)

Lymphoma | Multiple Myeloma | Oral Mucositis | Hematologic Cancer

Korea, Republic of
National Institute of Allergy and Infectious Diseases...
ViiV Healthcare

Completed

Long-Acting Cabotegravir Plus VRC-HIVMAB075-00-AB (VRC07-523LS) for Viral Suppression in Adults Living With HIV-1

HIV Infections

United States, Puerto Rico
Esperion Therapeutics, Inc.

Completed

Milk-Only Lactation Study to Evaluate the Concentration of Bempedoic Acid and Bempedoic Acid/Ezetimibe Fixed Combination Drug Product (FCDP) in the Breast Milk of Healthy Lactating Women

Healthy Lactating Women

United States
United States Naval Medical Center, Portsmouth

Completed

Levonorgestrel-Intrauterine System (LNG-IUS) Insertion in the Postpartum Period

Contraception

United States
QED Therapeutics, Inc.
Helsinn Healthcare SA

Terminated

Phase 3 Study of BGJ398 (Oral Infigratinib) in First Line Cholangiocarcinoma With FGFR2 Gene Fusions/Translocations

FGFR2 Gene Mutation | Advanced Cholangiocarcinoma

Korea, Republic of, United States, Belgium, Spain, Taiwan, China, United Kingdom, France, Canada, Germany, Thailand, Italy, Portugal, Australia, Puerto Rico
Cara Therapeutics, Inc.

Terminated

A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States
Cara Therapeutics, Inc.

Terminated

CR845-310302: A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States, Hungary, Australia, Germany, Korea, Republic of, Poland, Argentina, Brazil, Bulgaria, Italy, Mexico, Romania, Spain
Memorial Sloan Kettering Cancer Center
Context Therapeutics Inc.

Active, not recruiting

A Study of Onapristone ER Alone Or In Combination With Anastrozole in Gynecologic Cancers That Respond to Progesterone

Granulosa Cell Ovarian Cancer | Low Grade Serous Ovarian/ Primary Peritoneal Cancer | Endometrioid Endometrial Cancer

United States
Aclaris Therapeutics, Inc.

Terminated

Study of ATI-450 vs Placebo in Patients With Moderate to Severe Psoriatic Arthritis

Psoriatic Arthritis

United States, Poland
Atossa Therapeutics, Inc.

Active, not recruiting

Effect of Oral (Z)-Endoxifen in Premenopausal Women With Measurable Breast Density

Breast Density

Sweden
Fundacion Clinica Pardinas
Universidade da Coruña; University Hospital A Coruña

Active, not recruiting

Therapeutic Application of Coconut Oil in Oral Health

Periodontitis | Periodontal Diseases | Periodontal Attachment Loss | Periodontal Inflammation

Spain
Iterum Therapeutics, International Limited

Completed

Oral Sulopenem Versus Amoxicillin/Clavulanate for Uncomplicated Urinary Tract Infection in Adult Women (REASSURE)

Cystitis | Urinary Tract Infections

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Neuroblastoma | Ganglioneuroblastoma

United States, Canada, Puerto Rico
Ida Bruun Kristensen
Odense Patient Data Explorative Network; Karyopharm Therapeutics Inc

Active, not recruiting

Selinexor With Alternating Bortezomib or Lenalidomide Plus Dexamethasone in TIE Newly Diagnosed MM Patients (SABLe)

Multiple Myeloma

Denmark, Norway, Estonia
Cliniques universitaires Saint-Luc- Université...

Completed

Effect of an Oral Therapeutic Patient Education Session on Physical Activity in Patients With Cancer (ETAP)

Cancer

Belgium
Tvardi Therapeutics, Incorporated
M.D. Anderson Cancer Center

Active, not recruiting

Oral STAT3 Inhibitor, TTI-101, in Patients With Advanced Cancers

Melanoma | Breast Cancer | Colorectal Cancer | Gastric Adenocarcinoma | Non Small Cell Lung Cancer | Advanced Cancer | Head and Neck Squamous Cell Carcinoma | Hepatocellular Cancer

United States
University Hospital, Geneva

Completed

Antithrombotics' Therapeutic Optimization in Hospitalized Patients Using Physiologically- and Population-based Pharmacokinetic Modeling (OptimAT)

Cardiovascular Diseases

Switzerland
Atlas Molecular Pharma

Completed

Study to Assess the Safety and Pharmacokinetics of ATL-001 (Ciclopirox Olamine) in Healthy Volunteers

Adverse Effect of Drugs and Medicaments in Therapeutic Use

United States
Amicus Therapeutics

Active, not recruiting

First-In-Human Study to Evaluate Safety, Tolerability, and PK of Intravenous ATB200 Alone and When Co-Administered With Oral AT2221

Pompe Disease

United States, Netherlands, United Kingdom, Australia, Germany, New Zealand
Canadian Medical and Surgical Knowledge Translation...
Unity Health Toronto; Western University, Canada; HLS Therapeutics, Inc

Completed

The Use of Icosapent Ethyl on Vascular Progenitor Cells in Individuals With Elevated Cardiovascular Risk (IPE-PREVENTION)

Cardiovascular Diseases | Diabetes Mellitus, Type 2 | Cardiovascular Risk Factor | Triglycerides High

Canada
Celldex Therapeutics
Merck Sharp & Dohme LLC

Completed

A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies

Melanoma | Follicular Lymphoma | Renal Cell Carcinoma | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Pancreatic Adenocarcinoma | Ovarian Cancer | Fallopian Tube Cancer | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Lymphoplasmacytic Lymphoma | Non-Hodgkin Lymphoma | ... and other conditions

United States
SpringWorks Therapeutics, Inc.

Active, not recruiting

MEK Inhibitor Mirdametinib (PD-0325901) in Patients With Neurofibromatosis Type 1 Associated Plexiform Neurofibromas (ReNeu)

Plexiform Neurofibroma | Neurofibromatosis Type 1 (NF1)

United States
Yale University
National Center for Complementary and Integrative Health (NCCIH); Brain & Behavior...

Completed

Vitamin D as a Therapeutic Adjunct in the Stimulant Treatment of ADHD

ADHD

United States
Emergent BioSolutions
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Safety and Pharmacokinetics of UV-4B Solution Administered Orally as Multiple Ascending Doses to Healthy Subjects

Viral Infection

United States
Emergent BioSolutions
Quintiles, Inc.; Unither Virology

Completed

Study to Determine the Safety, Tolerability and Pharmacokinetics of UV-4B Solution Administered Orally in Healthy Subjects (UV)

Viral Infection

United States
QED Therapeutics, Inc.
Helsinn Healthcare SA

Terminated

Oral Infigratinib for the Adjuvant Treatment of Subjects With Invasive Urothelial Carcinoma With Susceptible FGFR3 Genetic Alterations (PROOF302)

Upper Tract Urothelial Carcinomas | Urothelial Bladder Cancer

United States, France, Canada, Spain, Italy, Belgium, Germany, Netherlands, United Kingdom, Bulgaria, Greece
National Institute of Allergy and Infectious Diseases...
Gilead Sciences; ViiV Healthcare

Active, not recruiting

Injectable Cabotegravir Compared to TDF/FTC For PrEP in HIV-Uninfected Men and Transgender Women Who Have Sex With Men

HIV Infections

Brazil, United States, South Africa, Peru, Thailand, Argentina, Vietnam
Fulcrum Therapeutics

Terminated

Losmapimod Safety and Efficacy in COVID-19 (LOSVID)

COVID-19

United States, Mexico, Brazil, Peru
Repare Therapeutics

Active, not recruiting

Study of RP-6306 With FOLFIRI in Advanced Solid Tumors (MINOTAUR)

Advanced Solid Tumor

United States, Canada, Spain, United Kingdom
Fulcrum Therapeutics

Active, not recruiting

Efficacy and Safety of Losmapimod in Treating Participants With Facioscapulohumeral Muscular Dystrophy (FSHD) (REACH)

Facioscapulohumeral Muscular Dystrophy (FSHD)

United States, Spain, Italy, Denmark, Canada, Germany, France, Netherlands, United Kingdom
Spero Therapeutics

Completed

A Study to Assess the Intrapulmonary Pharmacokinetics (PK) of SPR719 by Comparing the Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations Following the Oral Administration of Multiple Doses of SPR720 in Healthy Volunteers.

Healthy Volunteer

United States
Maastricht University Medical Center
Radboud University Medical Center

Completed

Exploratory Drug Interaction Study Between SMIs and DOACs

Solid Tumor | Cancer, Lung

Netherlands
Viracta Therapeutics, Inc.

Completed

Dose Escalation & Expansion Study of Oral VRx-3996 & Valganciclovir in Subjects With EBV-Associated Lymphoid Malignancies

Lymphoproliferative Disorders | Epstein-Barr Virus Associated Lymphoma

United States, Brazil
Cara Therapeutics, Inc.

Terminated

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis (KIND-1)

Pruritus | Atopic Dermatitis

United States
Family Planning Associates Medical Group, LTD
Merck Sharp & Dohme LLC; The Cleveland Clinic

Completed

Nexplanon Application Post-Abortion (NAPA) (NAPA)

Contraception | Abortion, Therapeutic

United States
AKARI Therapeutics

Withdrawn

Nomacopan Therapy in Adult Patients With Bullous Pemphigoid Receiving Adjunct Oral Corticosteroid Therapy (ARREST-BP) (ARREST-BP)

Bullous Pemphigoid

United States, Germany, Netherlands, Poland
Adiso Therapeutics

Completed

An Investigation of Oral BT051 in Subjects With Moderately to Severely Active Ulcerative Colitis (UC) (SCOUT)

Ulcerative Colitis

United States, Georgia, Moldova, Republic of, Poland
Organon and Co
IQVIA Inc.; OSTAtistics

Terminated

Contraceptive Efficacy and Safety of NOMAC-E2 Combined Oral Contraceptive

Contraception

United States
Regeneron Pharmaceuticals
Sanofi; Aimmune Therapeutics, Inc.

Completed

Study in Pediatric Subjects With Peanut Allergy to Evaluate Efficacy and Safety of Dupilumab as Adjunct to AR101 (Peanut Oral Immunotherapy)

Peanut Allergy

United States
University Hospital, Bordeaux

Terminated

Impact of the Information Follow-up Given to Patients on Their Disease Understanding and Therapeutic Adherence in Patients Under Direct Oral Anticoagulants and With Atrial Fibrillation in a Cardiology Department (RYTHM-UP AOD)

Atrial Fibrillation

France
University of Chicago
National Cancer Institute (NCI)

Active, not recruiting

Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating Patients With Recurrent Head and Neck Cancer

Tongue Cancer | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma of the Oropharynx | Recurrent Squamous Cell... and other conditions

United States
Repare Therapeutics

Active, not recruiting

Study of RP-6306 With Gemcitabine in Advanced Solid Tumors

Adult Solid Tumor

United States, Canada, United Kingdom
Malmö University
Odontologisk Forskning i Region Skåne (OFRS)

Completed

NOACs in Oral and Maxillofacial Surgery: Impact on Post-operative Complications

Postoperative Complications | Hemorrhage | Anticoagulant-induced Bleeding | Oral Surgical Procedures | Anticoagulants Causing Adverse Effects in Therapeutic Use | Surgery, Oral

Sweden

Search clinical trials for: oral therapeutic

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