Search clinical trials for: Inclisiran, LDL-C, monotherapy

Total 1625 results

Fundacion SEIMC-GESIDA
Abbott

Completed

Lopinavir/r Monotherapy Versus Abacavir/Lamivudine and Lopinavir/r for Limb Fat Recovery in Persons With Lipoatrophy (KRETA)

HIV Infections | HIV Infection | Lipodystrophy

Spain
Fundacion SEIMC-GESIDA
Abbott

Completed

Treatment of HIV/HCV Coinfection With Peg-IFN and Ribavirin in Patients Receiving ART Monotherapy With Lopinavir/r (PEKARI)

HIV Infections | HIV/HCV Co-infection

Spain
Sociedad Andaluza de Enfermedades Infecciosas

Completed

Clinical Trial, Open-label, Randomised, in Order to Compare the Quality of Life for Those VIH+ Patients That Start With Monotherapy on LPV/r Tablets Vs. Triple Therapy With a Boosted Protease Inhibitor (QoLKAMON)

HIV Infection

Spain
Bristol-Myers Squibb

Completed

Entecavir Plus Tenofovir Combination Therapy Versus Entecavir Monotherapy in Naive Subjects With Chronic Hepatitis B

Hepatitis B, Chronic

Australia, France, India, Italy, United States, Canada, Poland, Russian Federation, Argentina, South Africa, Brazil, Turkey, Mexico
GlaxoSmithKline

Completed

Lamotrigine Pregnancy Registry (LAM05)

Epilepsy | Bipolar Disorder
GlaxoSmithKline
Shionogi

Completed

A Study Comparing 4 Doses Of GW810781 Versus Placebo In HIV-Infected Patients

HIV Infections

United States
IBSA Institut Biochimique SA

Completed

Subcutaneous Progesterone Versus Vaginal Progesterone Tablets for Luteal Phase Support in In Vitro Fertilization (IVF)

In Vitro Fertilization

United States
United Therapeutics

Withdrawn

FREEDOM DR: Oral Treprostinil in Combination With an Endothelin Receptor Antagonist (ERA) and/or a Phosphodiesterase-5 (PDE-5) Inhibitor or as Monotherapy for the Treatment of Pulmonary Arterial Hypertension (PAH)

Pulmonary Hypertension

United States, Australia, Mexico
Pfizer

Completed

Three Dose Levels of CP-690,550 Monotherapy Versus Placebo, Administered Orally Twice Daily (BID) for 6 Weeks

Rheumatoid Arthritis

United States, Germany, Italy, Spain, Canada, Belgium, Slovakia, Brazil, Mexico
AstraZeneca

Terminated

Seroquel in Acute Mania: Study to Investigate if Valproate Add-On Therapy is Superior to Quetiapine Monotherapy in Acutely Manic Patients

Bipolar Disorder

Denmark
Gachon University Gil Medical Center

Unknown

Comparison of the Efficacy of Entecavir and Tenofovir Monotherapy for the Treatment of Nucleos(t)Ide-naïve Patients With Chronic Hepatitis B in Korea

Chronic Hepatitis B

Korea, Republic of
AstraZeneca

Completed

Protocol for the Specified Clinical Experience Investigation on the Single Use of Casodex® Tablet 80 mg (CAMON)

Prostate Cancer

Japan
University of Southampton
University Hospital Southampton NHS Foundation Trust

Unknown

Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors (GemTIP)

Testicular Germ Cell Tumor | Ovarian Cancer | Brain and Central Nervous System Tumors | Extragonadal Germ Cell Tumor

United Kingdom
Sanofi

Completed

Study of Efficacy and Safety of Irbesartan/Amlodipine 4 Fixed Combination Therapy in Hypertensive Patients Uncontrolled on Irbesartan or Amlodipine Monotherapy

Hypertension

Russian Federation
Janssen-Cilag International NV

Completed

Treatment Simplification by Darunavir/Ritonavir 800/100 mg Once a Day Versus a Triple Combination Therapy With Darunavir/Ritonavir (MONET)

HIV Infections | Human Immunodeficiency Virus | Acquired Immunodeficiency Syndrome Virus | AIDS Virus

United Kingdom, Belgium, Germany, Spain, Portugal, Israel, Denmark, Russian Federation, Austria, Hungary, Switzerland
Subhransu K. Ray, M.D., Ph.D.
Bay Area Retina Associates

Completed

A Prospective Study Comparing Ranibizumab Plus Dexamethasone Combination Therapy Versus Ranibizumab Monotherapy for Wet AMD (Lucedex)

Exudative Age-Related Macular Degeneration

United States
Yeungnam University College of Medicine

Completed

Combined Therapy of Posterior Subtenon Triamcinolone Acetonide and Intravitreal Bevacizumab for Macular Edema Secondary to Branch Retinal Vein Occlusion

Branch Retinal Vein Occlusion

Korea, Republic of
Novartis Pharmaceuticals
Baker Heart and Diabetes Institute

Completed

Valsartan Intensified Primary Care Reduction of Blood Pressure Study (VIPER-BP)

Hypertension

United States, Australia
AstraZeneca

Terminated

A Study to Assess the Safety and Effect of TC-5214 in Patients With Major Depressive Disorder.

Major Depressive Disorder

United States, Estonia, Japan, Finland, India
Inje University

Unknown

The Effect of Quetiapine XR in Depressive Patients Showing Aberrant N100 Amplitude Slope

Major Depressive Disorder

Korea, Republic of
Medical Research Council
NHS Health Technology Assessment Programme

Unknown

Protease Inhibitor Monotherapy Versus Ongoing Triple-therapy in the Long Term Management of HIV Infection (PIVOT) (PIVOT)

Acquired Immunodeficiency Syndrome | HIV Infection
AstraZeneca

Completed

30 Week Study of the Combination of ABT-335 and Rosuvastatin Compared to Rosuvastatin Monotherapy for Subjects With Dyslipidemia and Stage 3 Chronic Kidney Disease

Dyslipidemia | Kidney Disease

United States, Puerto Rico
AstraZeneca

Completed

A Multicenter Study Comparing the Safety and Efficacy of ABT-335 and Rosuvastatin Calcium Combination Therapy to Monotherapy in Subjects With Dyslipidemia

Dyslipidemia | Hypercholesterolemia

United States
University of Rochester
Juniper Pharmaceuticals, Inc.

Withdrawn

Vaginal Progesterone as a Treatment for Women Active Preterm Labor (VagPro)

Labor, Premature

United States
Allergan

Completed

GANfort® in Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Are Insufficiently Responsive to Monotherapy

Ocular Hypertension | Glaucoma, Open-Angle

Austria
Allergan

Completed

A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Were Insufficiently Responsive to Monotherapy

Ocular Hypertension | Glaucoma, Open-Angle

Spain
Kyowa Kirin Co., Ltd.

Completed

A Study of Istradefylline (KW-6002) for the Treatment of Parkinson's Disease

Parkinson's Disease

Japan
GlaxoSmithKline

Completed

Impact of Migraine on Work Productivity in Patients Treated With a Combination Product Containing Sumatriptan and Naproxen Sodium or Triptan Monotherapy

Migraine Disorders
Facet Biotech
Biogen

Terminated

A Phase 2, Single-Arm Study of Volociximab Monotherapy in Subjects With Platinum-Resistant Advanced Epithelial Ovarian Cancer or Primary Peritoneal Cancer

Peritoneal Neoplasms | Ovarian Cancer

United States, Canada
Bristol-Myers Squibb

Completed

Safety and Antiviral Activity of Entecavir in Participants With Chronic Hepatitis B Following Monotherapy in Other Entecavir Trials

HBV | Hepatitis B Virus
Seung-Jung Park
CardioVascular Research Foundation, Korea

Completed

Association of Clopidogrel Therapy and Stent Thrombosis (REAL-LATE)

Coronary Artery Disease

Korea, Republic of
AstraZeneca

Completed

Anastrozole Monotherapy Versus Maximal Oestrogen Blockade With Anastrozole and Fulvestrant Combination Therapy (FACT)

Breast Cancer

Sweden, France, Italy, Turkey, Germany, Norway, Finland, Portugal, Canada, Iceland, Costa Rica, Guatemala
Eisai Korea Inc.

Completed

Low and High Dose Zonisamide in Children as Monotherapy

Epilepsy

Korea, Republic of
GlaxoSmithKline

Completed

Monotherapy Versus Placebo Over 10 Days in Integrase Naive HIV-1 Infected Adults

Infection, Human Immunodeficiency Virus | HIV-1 Infection

United States
Azienda Ospedaliera Universitaria Senese

Unknown

A Clinical Study With Tremelimumab as Monotherapy in Malignant Mesothelioma

Malignant Mesothelioma

Italy
Pomeranian Medical University Szczecin
Maria Sklodowska-Curie National Research Institute of Oncology; Regional Oncology...

Unknown

Cisplatin-monotherapy in the Treatment of BRCA1 Positive Breast Cancer Patients in Poland

BRCA1 Mutation | Breast Cancer Invasive Nos

Poland
Massachusetts General Hospital

Completed

Effectiveness of Acupuncture for Depressed Patients Not Taking Antidepressant Medications

Depression

United States
University of Wisconsin, Madison

Completed

MMF Monotherapy and Immune Regulation in Kidney Transplant Recipients: Part 1 Steroid Withdrawal

Renal Transplantation

United States
Forest Laboratories

Completed

Efficacy and Safety Study to Evaluate Combination Therapy With Nebivolol and Lisinopril vs. Placebo and Monotherapy in Patients With Stage 2 Diastolic Hypertension

Stage 2 Diastolic Hypertension

United States, Puerto Rico
Dr. Claudia Bösmüller
Astellas Pharma GmbH

Completed

Effectiveness and Safety of Campath in Combination With Tacrolimus Monotherapy to Prevent Kidney Graft Rejection

Kidney Transplantation

Austria
SciClone Pharmaceuticals

Completed

Proof-of-concept Study to Evaluate the Safety and Immunomodulatory Effects of SCV 07 as Monotherapy or in Combination With Ribavirin in Noncirrhotic Subjects With Chronic Hepatitis C Who Have Relapsed

Chronic Hepatitis C

United States
GlaxoSmithKline

Terminated

Monotherapy Versus Placebo Over 14 or 17 Days in Healthy and Hepatitis C Infected Adults

Hepatitis C | Hepatitis C, Chronic

United States
AstraZeneca
Bristol-Myers Squibb

Completed

Screening Epidemiological Program on Compensation Evaluation of Diabetes Mellitus Type 2 (DMT2) Patients on Oral Anti-diabetic (OAD) Monotherapy and Physicians Satisfaction of Their Usage

Type 2 Diabetes

Russian Federation
Ottawa Hospital Research Institute
Abbott

Completed

Kaletra Monotherapy in HIV/HCV Co-infected Subjects

HIV Infections

Canada
AstraZeneca

Completed

Comparing Quetiapine XR Monotherapy and Augmentation With Lithium Augmentation in TRD Patients (RUBY)

Major Depressive Disorder | Treatment Resistant Depression

Bulgaria, Italy, United Kingdom, Germany, Hungary, Romania, Austria, Belgium, Denmark, Portugal, Slovakia, Australia, Spain
Lahey Clinic

Withdrawn

Pilot Study Reduced Fluence PDT /Visudyne With Ranibizumab vs Ranibizumab Monotherapy for Exudative Age-related Macular Degeneration (AMD)

Macular Edema
Philipps University Marburg Medical Center
UCB Pharma GmbH

Completed

Lamotrigine Versus Levetiracetam in the Initial Monotherapy of Epilepsy

Epilepsy

Germany
Nycomed

Withdrawn

RIAPRE - Non-interventional Registry of Anticoagulation Treatment (BI-006-IT)

Coronary Disease
Bristol-Myers Squibb

Completed

A Trial to Evaluate BMS-298585 as Monotherapy in Subjects With Type 2 Diabetes Who Have Inadequate Glycemic Control

Diabetes, Type 2

United States, Canada, Mexico, Puerto Rico, Australia, Poland, Taiwan
ikfe-CRO GmbH
Novartis Pharmaceuticals; IKFE Institute for Clinical Research and Development

Unknown

Effect of Adding Vildagliptin on Beta Cell Function and Cardiovascular Risk Markers in Patients With Moderate Metabolic Control During Metformin Monotherapy

Diabetes Mellitus Type II

Germany

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