Search clinical trials for: Hydromorphone challenge

Total 1586 results

University of Saskatchewan

Completed

Effects of Caffeine on Methacholine Challenge and Exhaled Nitric Oxide Levels.

Asthma

Canada
Pfizer

Completed

A Study To Assess The Effect Of PF-03526299 On Lung Function Following An Allergen Challenge In Asthmatic Subjects

Asthma

United Kingdom
ORA, Inc.

Completed

Conjunctival Allergen Challenge (CAC) Following Allergen Exposure in the Allergen BioCube (ABC) (ABC CAC)

Allergic Rhinoconjunctivitis

United States
National Institute of Allergy and Infectious Diseases...

Completed

RSV Challenge in Healthy Adults

Respiratory Syncytial Virus | Respiratory Infections, Acute

United States
Peking Union Medical College Hospital

Unknown

Assessment of Transcutaneous Oxygen Tension/Oxygen Challenge Test in Intensive Care Unit (ICU) Patients (ICUPtO2OCT)

Sepsis | Shock

China
Fraunhofer-Institute of Toxicology and Experimental...
German Research Foundation

Completed

Ex Vivo Effect of Surfactant Protein D on Pulmonary Immune Cells Derived From Bronchoalveolar Lavage After Segmental Allergen Challenge in Patients With Asthma

Asthma

Germany
Pfizer

Completed

A Study To Explore The Effect On Inflammatory Markers After Nasal Allergen Challenge In Subjects With Seasonal Allergic Rhinitis And The Effect Of A Single Dose Of Ibuprofen Or Fluticasone Propionate On The Allergen Response.

Allergic Rhinitis

United States
Alza Corporation, DE, USA

Completed

A Study of OROS Hydromorphone HCL vs Morphine in Cancer Pain Patients.

Pain | Analgesics, Opioid
Alza Corporation, DE, USA

Completed

A Repeated-Dose Evaluation of a Pain Relieving Drug Use and Safety of OROS Hydromorphone HCI in Patients With Chronic Non-Malignant Pain

Pain | Analgesics | Opioid
Alza Corporation, DE, USA

Completed

A Repeated-Dose Evaluation of Use of a Pain Relieving Drug and Safety of OROS Hydromorphone HCI in Patients With Chronic Cancer Pain

Pain | Analgesics, Opioid
Alza Corporation, DE, USA

Completed

Study of the Effectiveness and Tolerability of OROS Hydromorphone HCI SR(Slow-release) Tablets and Immediate-Release Hydromorphone Tablets in Patients With Chronic Pain

Pain
Alza Corporation, DE, USA

Completed

An Effectiveness, Safety and Quality of Life Measures With Hydromorphone HCL, Dilaudid CR (Controlled Release)

Osteoarthritis, Knee | Osteoarthritis, Hip
Alza Corporation, DE, USA

Completed

Safety and Tolerability of Long-Term Administration of Hydromorphone HCI CR (Controlled Release)

Pain | Analgesics, Opioid
Alza Corporation, DE, USA

Completed

Safety, Effectiveness, and Impact on Quality of Life on Long-Term Administration of OROS Hydromorphone Slow-Release in Patients With Chronic Low Back Pain

Low Back Pain
Alza Corporation, DE, USA

Completed

A Randomized, Open-Label, Single-Dose, Small Study to Evaluate the Safety and Effectiveness of Hydromorphone in Patients With Short Term, Moderate to Severe Postoperative Pain

Pain, Postoperative | Analgesia | Orthopedic Procedures
Alza Corporation, DE, USA

Completed

An Open-Label Evaluation of the Independent Effects of Coadministration of a High-Fat Meal and Naltrexone Blockade on the Pharmacokinetic Profile of Dilaudid OROS (Hydromorphone HCI) 16mg

Analgesia
Alza Corporation, DE, USA

Completed

An Open-Label Evaluation of the Dose Proportionality of OROS� Hydromorphone HCL Tablets 8mg, 16mg, 32mg, 64mg

Analgesia
Alza Corporation, DE, USA

Completed

A Study on Efficacy (Effectiveness), Safety, and Impact on Quality of Life Measures of Dilaudid CR (Controlled Release);, Hydromorphone HCl in Patients With Chronic Low Back Pain

Low Back Pain
Alza Corporation, DE, USA

Completed

Safety and Tolerability of Long-term Administration of OROS Hydromorphone HCI (Slow Release) in Cancer Pain

Pain | Analgesics, Opioid
Novartis Pharmaceuticals

Completed

Effect of AIN457 on Ozone-induced Airway Neutrophilia Compared to Placebo and Corticosteroid in Healthy Subjects

Healthy

Germany
National Institute on Aging (NIA)

Completed

The LIFE Study: Lifestyle Interventions and Independence for Elders, Pilot

Aging | Physically Challenged

United States
Malaria Vaccine and Drug Development Center
Ministerio de la Protección Social, Colombia.

Completed

Establishment of a Sporozoite Challenge Model for Plasmodium Vivax in Human Volunteers (ChallengeII)

Malaria, Vivax

Colombia
Hordinsky, Maria K., MD

Terminated

Topical Hydromorphone for Wound Healing

Wound Healing

United States
University Hospital, Toulouse

Completed

Motor Activation in Multiple System Atrophy and Parkinson Disease: a Positron Emission Tomography (PET) Study (MSAJOY)

Multisystemic Atrophy

France
St George's, University of London
University of British Columbia; Bill and Melinda Gates Foundation; Wellcome Trust and other collaborators

Completed

Human Innate Immune Responses To Mycobacterial Aerodigestive Tract Infection (UBC-INNATE01)

Bacterial Infections

United Kingdom
Oxagen Ltd
King's College Hospital NHS Trust; Medicines Evaluation Unit, Manchester, UK

Completed

OC000459 Bronchial Allergen Challenge

Bronchial Asthma

United Kingdom
Pfizer

Completed

A Study To Assess The Effect Of PF-03893787 On Lung Function Following An Allergen Challenge In Asthmatic Subjects

Asthma

United Kingdom
University of Vermont
Naval Medical Research Center; United States Army Medical Materiel Development...

Unknown

Campylobacter Jejuni Challenge Model Development: Assessment of Homologous Protection

Campylobacter Infections

United States
Pharmaxis

Completed

Ability of Aridol to Detect Bronchial Hyperresponsiveness in Suspected Asthmatics

Asthma

United States
University of Saskatchewan

Completed

Methacholine Challenge: Comparison of Doubling and Quadrupling Methacholine Dose Regimes Using the Tidal Volume Method

Asthma

Canada
Hamilton Health Sciences Corporation

Completed

The Effects Of Methacholine Challenge Administered Using Three Different Nebulizers On Small Airways Function

Asthma

Canada
Nanjing Medical University
HRSA/Maternal and Child Health Bureau

Completed

Intravenous Remifentanil for Labor Analgesia (IRELAN)

Labor Pain

China
Pfizer

Terminated

Evaluation Of PF-00572778 And Alprazolam On Naloxone Challenge In Healthy Subjects

Healthy

United States
University of California, Los Angeles

Completed

Cytokine-Associated Depression and Social Pain

Depression

United States
GlaxoSmithKline

Completed

Allergen Challenge Chamber Study With Single Dose Intranasal GSK1004723 Compared With Placebo

Allergic Rhinitis

Germany
AstraZeneca
KuDOS Pharmaceuticals Limited

Completed

A Study to Assess the Safety and Pharmacokinetics of an Inhibitor of PARP in Combination With Dacarbazine

Melanoma Neoplasms

United States, United Kingdom
Dana-Farber Cancer Institute
Massachusetts General Hospital; Beth Israel Deaconess Medical Center; Brigham...

Completed

Thalidomide in Combination With Temodar in Patients With Neuroendocrine Tumors

Neuroendocrine Tumor

United States
University Hospital Inselspital, Berne
Edwards Lifesciences

Completed

Pulse Contour Analysis and Tissue Oxymetry in Changing Vascular Tone

Vasodilation | Vasoconstriction | Hemodynamics | Cardiac Output, Low | Cardiac Output, High

Switzerland
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Novel Noninvasive Techniques to Study Neutrophil Airway Inflammation in an Ozone Challenge Model

Healthy Subjects

Germany
TD Vaccines A/S
Johns Hopkins University; University of Vermont; SNBL Clinical Pharmacology Center... and other collaborators

Unknown

ACE393-103 Vaccination Challenge Study (ACE393-103VC)

Campylobacter Infection

United States
Technische Universität Dresden

Completed

Cetuximab in Neoadjuvant Treatment of Non-Resectable Colorectal Liver Metastases (CELIM)

Colorectal Cancer | Liver Metastases

Germany, Austria
Oxagen Ltd

Completed

OC000459 Dose Finding Study in Hay Fever Sufferers.

Allergic Rhinitis

Austria
University of Dundee
Tenovus Scotland

Completed

Antibiotics for the Treatment of Ulcerative Colitis

Colitis, Ulcerative

United Kingdom
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Interferon Alfa-2b With or Without Thalidomide in Treating Patients With Metastatic or Unresectable Kidney Cancer

Kidney Cancer

United States, Australia, Peru, Puerto Rico
SCRI Development Innovations, LLC
CTI BioPharma

Completed

Arsenic Trioxide and Thalidomide in the Treatment of Refractory Multiple Myeloma

Multiple Myeloma
US Department of Veterans Affairs

Completed

Hyporeactivity and Gulf War Illness

Gulf War Syndrome | Chronic Fatigue Syndrome | Post-Traumatic Stress Disorder

United States
Akela Pharma, Inc.

Unknown

Safety of Fentanyl TAIFUN Treatment (FINDS)

Breakthrough Cancer Pain

Poland
Northwell Health

Completed

Continuous Lumbar Plexus Block for Postoperative Pain Control After Total Hip Arthroplasty

Postoperative Pain
Erasmus Medical Center

Terminated

The Pain Pen for Breakthrough Cancer Pain

Neoplasms | Pain

Netherlands
Waikato Hospital
Waikato Hospital Research Fund

Completed

Beta-Blocker in Chronic Obstructive Pulmonary Disease (COPD) Study (BOLD)

Chronic Obstructive Pulmonary Disease

New Zealand

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