Search clinical trials for: Phase I/II

Total 18517 results

Herlev Hospital

Unknown

Low-Dose Endotoxemia and the Acute Phase Response

Sepsis | Endotoxemia

Denmark
Case Western Reserve University

Completed

Overcoming Nutritional Barriers in Hemodialysis Patients

End Stage Renal Disease
National Health Research Institutes, Taiwan

Completed

Phase III Study OF the Gastric Surgery on Advanced Stage Gastric Cancer

Gastric Cancer
University Hospital, Angers

Unknown

High Dose Hyperoncotic Serum Albumin for the Treatment of the Acute Phase of Severe Head Injury

Severe Head Injury

France
Poitiers University Hospital
Novartis; Ministry of Health, France

Terminated

Safety and Efficacy of Imatinib in Combination With High Dose Chemotherapy for Acute Phase Chronic Myelogenous Patients

Chronic Myeloid Leukemia

France
National Taiwan University Hospital
National Health Research Institutes, Taiwan

Completed

A Phase II Study of Radiotherapy for Locally Advanced Hepatocellular Carcinoma (HCC)

Hepatocellular Carcinoma
University Hospital, Gentofte, Copenhagen

Unknown

Substitution of First Phase Insulin Response in Patient With Type 2 Diabetes.

Type 2 Diabetes

Denmark
Boston University

Completed

Phase II Study of Arginine Butyrate With or Without Epoetin Alfa in Patients With Thalassemia Intermedia

Beta-Thalassemia

United States, United Kingdom
Celgene Corporation
Prologue Research International

Terminated

Phase I Open-Label, Dose Escalation Study To Determine The Maximum Tolerated Dose And To Evaluate The Safety Profile Of Lenalidomide (Revlimid®, CC-5013) With Pemetrexed In Subjects With Advanced Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

United States
Celgene Corporation
Prologue Research International

Terminated

A Phase I/II Study of Lenalidomide in Combination With Gemcitabine in Patients With Untreated Advanced Carcinoma of the Pancreas

Pancreatic Cancer

United States
Zeneus Pharma

Unknown

Open Label, Single Arm, Phase II Study Using R-COMP in Elderly Patients With Aggressive NHL.

Aggressive Non-Hodgkin's Lymphoma in the Elderly.

France, Germany, Spain, United Kingdom, Italy
University Hospital, Rouen

Completed

Weekly Cisplatin/Irinotecan and Radiotherapy in Patients With Locally Advanced Esophageal Cancer: Phase II Trial

Esophageal Neoplasms

France
Cell Genesys

Completed

A Phase II Trial of CG 8020 and CG 2505 in Patients With Nonresectable or Metastatic Pancreatic Cancer

Metastatic Pancreatic Cancer | Nonresectable Pancreatic Cancer

United States
University Hospital, Angers
French Innovative Leukemia Organisation

Unknown

Description and Prognostic Evaluation of Four Biological Parameters of Blast Cells in Adult Acute Lymphoblastic Leukemia

Adult Acute Lymphoblastic Leukemia

France
Integrated Community Oncology Network
Sanofi

Unknown

Phase II Study of Oxaliplatin and Navelbine for Second-Line Treatment of Advanced NSCLC.

Previously Treated Metastatic Non-Small Cell Lung Cancer

United States
Kyoto University, Graduate School of Medicine

Unknown

Phase I/II Study of Recombinant Human Hepatocyte Growth Factor in Fulminant Hepatic Failure

Liver Failure, Acute

Japan
University of British Columbia
Canadian Institutes of Health Research (CIHR)

Completed

Early Labour Assessment and Support at Home

Latent Phase Labour
Department of Veterans Affairs, New Jersey
Sanofi; Pfizer

Unknown

A Phase II Trial of Combination Therapy With Celecoxib and Taxotere for the Treatment of Stage D3 Prostate Cancer

Prostate Cancer

United States
Hokkaido Gastrointestinal Cancer Study Group

Completed

Phase I / II Study of Irinotecan (CPT-11) Combined With l-Leucovorin (l-LV) and 5-FU in Patients With Advanced Colorectal Cancer

Colorectal Cancer

Japan
Association Européenne de Recherche en Oncologie
Amgen; Aventis Pharmaceuticals

Completed

Randomized Phase II Trial of Dose Dense Docetaxel in N+ Breast Cancer

Node Positive Breast Cancer
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

PHASE III TRIAL COMPARING, NEOADJUVANT CHEMOTHERAPY FOLLOWED BY STANDARD RADIOTHERAPY VERSUS THE SAME NEOADJUVANT CHEMOTHERAPY FOLLOWED BY STANDARD RADIOTHERAPY ASSOCIATED WITH DAILY HYDROXYUREA IN THE TREATMENT OF LOCALLY ADVANCED UNDIFFERENTIATED CARCINOMA NASOPHARYNGEAL TYPE.

LOCALLY ADVANCED UNDIFFERENTIATED CARCINOMA NASOPHARYNGEAL TYPE UCNT

France
University of British Columbia
National Cancer Institute (NCI)

Completed

A Phase IIb Trial of Pulmicort Turbuhaler (Budesonide)

Lung Cancer

Canada
National Taiwan University Hospital
National Health Research Institutes, Taiwan

Completed

Phase I/II Trial GOFL in Advanced Pancreatic Adenocarcinoma

Pancreatic Adenocarcinoma

Taiwan
UMC Utrecht
Dutch Kidney Foundation; Dianet Dialysis Centers

Completed

Effects of Daily Home Hemodialysis on Circulation, Mental Functions, and Quality of Life

End-Stage Renal Disease

Netherlands
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Assessment of Heart and Heart-Lung Transplant Patient Outcomes Following Pulmonary Rehabilitation

Lung Diseases | Bronchiectasis | Emphysema | Cystic Fibrosis | Alveolitis, Fibrosing

United Kingdom
West Japan Thoracic Oncology Group

Completed

A Randomized Phase III Trial of Chemotherapy Alone Versus Chemotherapy Followed by Gefitinib in Stage IIIB/IV Non-Small Cell Lung Cancer

Lung Cancer
National Institute on Drug Abuse (NIDA)
University of Vermont

Completed

Alternate Day Buprenorphine Administration, Phase X - 15

Opioid-Related Disorders

United States
National Institute on Drug Abuse (NIDA)
University of Vermont

Completed

Alternate Day Buprenorphine Administration, Phase XII - 17

Opioid-Related Disorders

United States
Pharmasset

Completed

A 14-Day Study of Racivir When Used in Combination in HIV-Infected Males

HIV Infections
Pharmasset

Completed

A Study of DPC 817 in HIV-Infected Males

HIV Infections

United States, Germany
Sandoz

Completed

A Phase I/II Study of Recombinant Human GM-CSF in Patients With AIDS Virus Infection and Leukopenia

HIV Infections | Cytopenias

United States
G D Searle

Completed

Initial Phase II Efficacy and Safety Study of SC-48334 Administered in Combination With Low-Dose Zidovudine (AZT) to Symptomatic HIV-1 Infected Patients With = or > 200 to = or < 500 CD4+ Cells/mm3

HIV Infections

United States
National Center for Research Resources (NCRR)
Oregon Health and Science University

Unknown

Phase II Study of Cholesterol- and Cholestanol-Free Diet, Lovastatin, and Chenodeoxycholic Acid for Cerebrotendinous Xanthomatosis

Cerebrotendinous Xanthomatosis

United States
National Center for Research Resources (NCRR)
James Whitcomb Riley Hospital for Children

Completed

Phase II Pilot Study of Granulocyte Colony-Stimulating Factor for Inherited Bone Marrow Failure Syndromes

Thrombocytopenia | Dyskeratosis Congenita | Fanconi's Anemia | Shwachman Syndrome
G D Searle

Completed

Phase II Study of the Safety and Surrogate Marker Efficacy of Butyldeoxynojirimycin (SC-48334) and AZT in Symptomatic HIV-1 Infected Patients With 200 - 500 CD4+ Cells/mm3. (NOTE: Asymptomatic HIV-1 Infected Patients Also Eligible)

HIV Infections

United States
National Center for Research Resources (NCRR)
University of Pennsylvania

Completed

Phase I Study of Ex Vivo Liver-Directed Gene Therapy for Familial Hypercholesterolemia

Familial Hypercholesterolemia
Genentech, Inc.

Completed

A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 (rCD4) in Patients With AIDS and AIDS-Related Complex

HIV Infections

United States
Nexstar Pharmaceuticals

Completed

A Randomized Phase III Clinical Trial of Daunoxome Versus Combination Chemotherapy With Adriamycin/Bleomycin/Vincristine (ABV) in the Treatment of HIV-Associated Kaposi's Sarcoma.

HIV Infections | Sarcoma, Kaposi

United States
National Center for Research Resources (NCRR)
University of Pittsburgh

Unknown

Phase II Study of Glucocerebrosidase in Patients With Gaucher Disease

Gaucher's Disease

United States
National Center for Research Resources (NCRR)
Mayo Clinic

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of 3,4-Diaminopyridine for Demyelinating Polyneuropathy

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Chiron Corporation

Completed

A Phase I Study of Subcutaneously Administered Proleukin (Aldesleukin) in HIV-Infected Patients

HIV Infections

United States
National Center for Research Resources (NCRR)
University of California, San Diego

Completed

Phase II Study of Ribose, Uridine, and Thymidine for a Complex Syndrome Involving Excessive 5'-Nucleotidase Activity

5'-Nucleotidase Syndrome
National Institute of Neurological Disorders and...
Seattle Children's Hospital

Unknown

Phase II Randomized Study of Selective Dorsal Rhizotomy and Physiotherapy Vs Physiotherapy Alone for Spastic Diplegia

Spastic Diplegia
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.

Completed

A Phase I Study of the Safety and Pharmacokinetics of Recombinant Human CD4 Immunoglobulin (rCd4-IgG) Administered by Intravenous Bolus in Patients With AIDS and AIDS Related Complex

HIV Infections

United States
National Center for Research Resources (NCRR)
University of Texas

Completed

Phase I Study of Heme Arginate With or Without Tin Mesoporphyrin in Patients With Acute Attacks of Porphyria

Porphyria
National Center for Research Resources (NCRR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University...

Completed

Phase III Randomized, Double-Blind Study of Potassium Phosphate Vs Potassium Citrate for Absorptive Hypercalciuria

Kidney Calculi | Hypercalciuria
Glaxo Wellcome

Completed

A Phase I Study to Evaluate the Pharmacokinetics, Safety and Antiviral Effects of Concurrent Administration of Zidovudine (AZT) and 2'3'-Dideoxyinosine (ddI) in Patients With Human Immunodeficiency Virus (HIV)

HIV Infections

United States
National Center for Research Resources (NCRR)
University of Vermont

Completed

Phase III Multicenter Double Blind Controlled Trial of Human Immune Globulin Therapy in Previously Untreated Patients With Chronic Inflammatory Demyelinating Neuropathy

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
University of Minnesota

Unknown

Phase I Pilot Study of CD34 Enriched, Fanconi's Anemia Complementation Group C Gene Transduced Autologous Peripheral Blood Stem Cell Transplantation in Patients With Fanconi's Anemia

Fanconi's Anemia
National Institute on Drug Abuse (NIDA)
University of Vermont

Completed

Alternate-Day Buprenorphine Administration. Phase I - 3

Opioid-Related Disorders

United States

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