Clinical Trials Sponsored by Aspire Medical

Total 56855 results

Shire

Completed

A Study To Monitor Long-Term Treatment With PF-00547659 (OPERA II)

Crohn's Disease

Korea, Republic of, United States, Spain, France, Serbia, Netherlands, Germany, Japan, Austria, Belgium, Poland, Canada, Norway, Slovakia, South Africa
Shire

Withdrawn

Pharmacokinetics of Granule and Tablet Formulations of Deferitazole (Disodium Salt) and a Capsule Formulation of Deferitazole (Magnesium Hydroxide Salt)

Healthy

United States
Shire

Completed

Safety and Pharmacology Study of VP 20629 in Adults With Friedreich's Ataxia

Friedreich's Ataxia

United States
Shire

Completed

Study of C1 Inhibitor (Human) for the Prevention of Angioedema Attacks and Treatment of Breakthrough Attacks in Japanese Subjects With Hereditary Angioedema (HAE)

Hereditary Angioedema (HAE)

Japan
Shire

Withdrawn

Treatment of Iron Overload Requiring Chelation Therapy

Metabolic Diseases | Iron Metabolism Disorders | Iron Overload | Beta-thalassemia | Transfusional Hemosiderosis | Transfusional Iron Overload | Iron Chelation
Shire

Terminated

FST-201 In The Treatment of Acute Otitis Externa

Acute Otitis Externa

United States
Shire

Terminated

FST-201 In The Treatment of Acute Fungal Otitis Externa

Acute Fungal Otitis Externa

United States
Shire

Completed

Calcium Supplementation in Postmenopausal Women (CAP)

Osteoporosis

United States, Argentina, Mexico
Shire

Approved for marketing

Treatment Protocol of Velaglucerase Alfa for Patients With Type 1 Gaucher Disease

Gaucher Disease, Type 1

United States
Shire

Completed

EDEMA2: Evaluation of DX-88's Effect in Mitigating Angioedema

Hereditary Angioedema (HAE)
Shire

Completed

A Study to Assess the Safety and Efficacy of 3 Doses of ALX1-11 (50, 75, and 100µg) in the Treatment of Postmenopausal Osteoporosis

Osteoporosis

United States, Canada
Shire

Completed

Open Label Extension (TRES)

Osteoporosis

United States, Argentina
Shire

Completed

Maribavir for Prevention of CMV After Stem Cell Transplants

Cytomegalovirus Infection

United States
Shire

Completed

Safety, Efficacy and Pharmacokinetic Study of Teduglutide in Infants 4 to 12 Months of Age With Short Bowel Syndrome

Short Bowel Syndrome

Finland, Italy, United Kingdom, France
Shire

Terminated

Efficacy and Safety Study of Ontamalimab as Induction Therapy in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 305) (CARMEN CD 305)

Crohn's Disease

United States, Australia, Romania, Israel, Italy, Croatia, South Africa, Germany, Poland, United Kingdom, Austria, Japan, Lithuania, Netherlands, Russian Federation, Serbia
Shire

Terminated

Mucopolysaccharidosis (MPS) I, II, and VI Screening in a High-Risk Population With Previous Surgical Repair or Presence of Inguinal and/or Umbilical Hernia in Combination With Pediatric ENT Surgery (The HATT Project)

Mucopolysaccharidosis (MPS)

United States, Canada, United Kingdom, Turkey, Italy, Mexico, Spain
Shire

Completed

Pediatric Disease Registry in Essential Thrombocythaemia (ET)

Essential Thrombocythemia (ET)

United Kingdom, Italy, Czechia, France, Germany, Greece, Spain, Switzerland
Shire

Completed

Home Therapy With Replagal in Fabry Disease

Fabry Disease

Austria, Germany
Shire

Terminated

Natural History Study of Children With Metachromatic Leukodystrophy

Metabolic Diseases | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Demyelinating Diseases | Genetic Diseases, Inborn | Metabolism, Inborn Errors | Lysosomal Storage Diseases | Lipid Metabolism Disorders | Sphingolipidoses | Hereditary Central Nervous System Demyelinating Diseases and other conditions

United States, Denmark, France, Argentina, Belgium, Brazil, Canada, Germany, Japan, Turkey
Shire

Completed

An Extension Study to Evaluate Maintenance of Efficacy and Long-term Treatment Effect of Oral Budesonide Suspension (OBS) in Adults and Adolescents With Eosinophilic Esophagitis (EoE) (ORBIT2)

Eosinophilic Esophagitis (EoE)

United States
Spine Wave

Completed

Annex™ Adjacent Level System for Treatment of Adjacent Level Disease

Degenerative Disc Disease | Adjacent Level Disease

United States
Shire

Completed

Study of Teduglutide in Japanese Participants With Short Bowel Syndrome

Short Bowel Syndrome

Japan
Titan Spine

Terminated

Titan Spine Endoskeleton TT/TO Study

Degenerative Disc Disease, Spondylolisthesis

United States
Stryker Spine

Terminated

AccuLIF® PROSPECTIVE PATIENT OUTCOMES STUDY (APROPOS)

Degenerative Disc Disease | Spondylolisthesis, Grade 1 | Retrolisthesis

United States
Spine Wave

Terminated

Clinical Evaluation of GENEX® DS in Instrumented Posterolateral Fusion

Degenerative Disc Disease | Spondylolisthesis | Stenosis

United States
Premia Spine

Unknown

Post-market Study of the TOPS™ System (TOPS)

Lumbar Spinal Stenosis | Spondylolisthesis

United Kingdom
Paradigm Spine

Completed

A Randomized Controlled Trial Comparing Surgical Decompression With an Interlaminar Implant in Patients With Intermittent Neurogenic Claudication Caused by Lumbar Stenosis (FELIX)

Intermittent Neurogenic Claudication (INC) as a Result of Spinal Stenosis

Netherlands
DePuy Spine

Completed

CHARITE™ vs. ALIF 5-Year Follow-up

Degenerative Disc Disease

United States
Bayer
Shire

Completed

Long-term Study in Chronic Kidney Disease (Extension From Study 14817)

Hyperphosphatemia

Japan
DePuy Spine

Completed

Titanium Surgical Mesh and MOSS-Miami Screws for Lumbar Fusion.

Degenerative Disc Disease

United States
Centinel Spine

Recruiting

2-level Cervical Disc Replacement Comparing Prodisc C SK & Vivo to Mobi-C (SMART)

Symptomatic Cervical Disc Disease

United States
Shire

Active, not recruiting

A Study of Replagal in Children and Adults With Fabry Disease in India

Fabry Disease

India
Shire

Completed

A Safety Extension Study of Ontamalimab in Participants With Moderate to Severe Ulcerative Colitis or Crohn's Disease (AIDA)

Crohn's Disease | Ulcerative Colitis

Spain, United States, Korea, Republic of, Lebanon, Australia, Russian Federation, Romania, Hungary, Portugal, Israel, Italy, Turkey, Croatia, Belgium, Bulgaria, Germany, Netherlands, Poland, New Zealand, Argentina, United Kingdom, Greec... and more
Shire

Completed

Intensive Pharmacovigilance Program for Elaprase (SHP ELA-701)

Hunter Syndrome

Mexico
Shire

Terminated

Safety and Efficacy Study of rhPTH(1-84) in Subjects With Hypoparathyroidism

Hypoparathyroidism

United States, Hungary, Denmark, Canada
Shire

Completed

Long-term Safety and Efficacy Outcome Study Comparing Children Previously Enrolled in Study ROPP-2008-01 for the Prevention of Retinopathy of Prematurity (ROP) (PEDAL)

Retinopathy of Prematurity (ROP)

United States, Italy, Netherlands, Poland, Sweden, United Kingdom
Shire

Terminated

Efficacy and Safety Study of Ontamalimab as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 307) (CARMEN CD 307)

Crohn's Disease

Spain, United States, Korea, Republic of, Australia, Romania, Hungary, Israel, Italy, Croatia, Belgium, Bulgaria, Germany, Poland, Portugal, Argentina, United Kingdom, Greece, New Zealand, Austria, Bosnia and Herzegovina, Colombia, Eston... and more
Shire

Completed

Efficacy and Safety Study of Maribavir Treatment Compared to Investigator-assigned Treatment in Transplant Recipients With Cytomegalovirus (CMV) Infections That Are Refractory or Resistant to Treatment With Ganciclovir, Valganciclovir, Foscarnet, or Cidofovir

Cytomegalovirus (CMV)

United States, Italy, France, Spain, Australia, Germany, Canada, United Kingdom, Belgium, Croatia, Austria, Denmark, Singapore, Switzerland
Shire

Completed

A Study Evaluating the Efficacy of SAR 1118 (0.1%, 1.0%, 5.0%) Ophthalmic Solution in Subjects With Dry Eye Conducted in a Controlled Adverse Environment (CAE)

Dry Eye

United States
Shire

Completed

Exploratory Multi-centre Trial In Patients With ET Treated With XAGRID® (EMIX)

Essential Thrombocythemia (ET)

Italy
Shire

Completed

A Relative Bioavailability Study of SSP-004184AQ (Magnesium Salt) and SSP-004184SS (Disodium Salt)

Healthy

United States
Shire

Completed

SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder

Binge Eating Disorder

United States, Germany
Shire

Completed

Sulfamethoxazole Drug Interaction Study With MMX® Mesalazine/Mesalamine

Healthy

United States
Shire

Withdrawn

A Study of SPD465 in Young Adult Drivers With Attention-Deficit Hyperactivity Disorder (ADHD) Using Driving Simulators

Attention Deficit Hyperactivity Disorder

United States
Shire

Completed

Study to Investigate Prucalopride vs. Polyethylene Glycol 3350 on Colon Activity

Chronic Constipation

United States, Belgium, United Kingdom
Shire

Completed

A Study of Gene-Activated® Human Glucocerebrosidase (GA-GCB) Enzyme Replacement Therapy in Gaucher Disease

Gaucher Disease, Type 1

Israel, Paraguay, Argentina, Russian Federation, Tunisia
Shire

Terminated

Study for Transfusionally Iron Overloaded Children, Adolescents and Adults Using FBS0701 (SSP-004184)

Iron Overload Due to Repeated Red Blood Cell Transfusions

Canada, United States, Thailand, Italy, United Kingdom
Shire

Completed

The Pharmacokinetics of Anagrelide in Elderly and Young Patients With Essential Thrombocythaemia (ET)

Essential Thrombocythaemia

Sweden, United Kingdom, Spain
Shire

Completed

A Safety and Dose Ranging Study of Idursulfase (Intrathecal) Administration Via an Intrathecal Drug Delivery Device in Pediatric Patients With Hunter Syndrome Who Have Central Nervous System Involvement and Are Receiving Treatment With Elaprase®

Hunter Syndrome

United States, United Kingdom
Shire

Completed

Study of PVS-10200 for the Treatment of Restenosis in Patients With Peripheral Artery Disease (TRIUMPH) (TRIUMPH)

Peripheral Artery Disease

France

Clinical Trials Sponsored by Aspire Medical

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