Clinical Trials Sponsored by Mclean Hospital

Total 101381 results

Mclean Hospital
National Institute of Mental Health (NIMH)

Recruiting

Beyond Monoamines: The Role of the Nociceptin/Orphanin FQ Receptor in Major Depression

Major Depressive Disorder

United States
Mclean Hospital
National Institute on Drug Abuse (NIDA)

Completed

The Women's Recovery Group Study: Stage I Trial

Substance-Related Disorders | Alcohol-Related Disorders

United States
Mclean Hospital
National Institute of Mental Health (NIMH)

Completed

Neural Components Underlying the Treatment of Adolescent Depression

Major Depressive Disorder

United States
Mclean Hospital
National Institute of Mental Health (NIMH)

Completed

Neurobiology of a Mutation in Glycine Metabolism in Psychotic Disorders

Bipolar Disorder | Schizo-affective Disorder

United States
Mclean Hospital
National Institute on Drug Abuse (NIDA)

Completed

Nicotine Related Brain Activity: The Influence of Smoking History and Blood Nicotine Levels

Nicotine Dependence

United States
National Institute on Drug Abuse (NIDA)
Mclean Hospital

Completed

Treatment Efficacy for Drug Abuse and AIDS Prevention - 2

Heroin Dependence | Cocaine-Related Disorders

United States
Mclean Hospital
National Institute of Mental Health (NIMH)

Completed

Understanding Brain Reward Responses in Individuals With Major Depressive Disorder

Depression

United States
Mclean Hospital
Ortho-McNeil Janssen Scientific Affairs, LLC

Completed

Follow-Up Extension to the Family Study of Binge Eating Disorder

Binge Eating Disorder

United States
Mclean Hospital
National Institute of Mental Health (NIMH)

Completed

Effect of Uridine on GABA and High Energy Phosphate Levels in Healthy Volunteers (Uridine-GABA)

Healthy Male Subjects

United States
Mclean Hospital
National Institute on Drug Abuse (NIDA)

Recruiting

Following Outcomes Remotely Within Addiction Recovery Domains (FORWARD)

Opioid Use Disorder

United States
Mclean Hospital
National Institute on Drug Abuse (NIDA)

Recruiting

Women's Opioid Treatment Follow-up Study

Opioid Use Disorder

United States
Mclean Hospital
National Institute on Drug Abuse (NIDA)

Recruiting

Pain, Inflammation and Opioid Craving

Opioid-use Disorder

United States
Mclean Hospital
National Institute of Mental Health (NIMH)

Recruiting

Neuroeconomics of Social Behavior Following Trauma Exposure

Posttraumatic Stress Disorder

United States
Centre for Addiction and Mental Health
Mclean Hospital

Completed

Community Reinforcement Approach and Family Training for Substance Use in Early Psychosis Intervention (CRAFT-EPI)

Schizophrenia Spectrum and Other Psychotic Disorders | Substance Use | Substance Use Disorders | Psychosis | Schizophrenia and Related Disorders

Canada
Mclean Hospital
National Institute on Drug Abuse (NIDA)

Completed

Families With Substance Use and Psychosis: A Pilot Study

Schizophrenia | Schizoaffective Disorder | Tobacco Use | Bipolar Disorder | Cannabis | Substance Use | Substance Use Disorders | Psychosis | Alcohol Use Disorder | Mental Disorder | Cigarette Smoking | Nicotine Use Disorder | Family | Marijuana | Alcohol

United States
Mclean Hospital
National Institute of Mental Health (NIMH)

Completed

Treatment to Enhance Cognition in Bipolar Disorder (TREC-BD)

Bipolar Disorder | Psychosis

United States
Mclean Hospital
National Institute of Mental Health (NIMH)

Terminated

Cognitive Control Training for Urgency in a Naturalistic Clinical Setting

Mental Disorders | Impulsive Behavior

United States
Mclean Hospital
National Institute of Mental Health (NIMH)

Completed

Brain Mechanisms of Emotion and Motivation: A Mind-Body Study (MIDAS)

Healthy | Anhedonia | Stress

United States
Mclean Hospital
National Institute of Mental Health (NIMH)

Completed

The Effects of Dopamine on Reward Processing

Major Depressive Disorder (MDD)

United States
Mclean Hospital
National Institute on Drug Abuse (NIDA)

Completed

Effect of Nicotine on Brain Reward Pathways

Depressive Disorder

United States
Pine Rest Christian Mental Health Services
Mclean Hospital

Completed

Study of Electroconvulsive Therapy (ECT) Treatment for Agitation and Aggression in Dementia

Aggression | Dementia | Agitation

United States
Mclean Hospital
National Institute on Drug Abuse (NIDA)

Unknown

Imaging the Effects of Zolpidem and Alprazolam in Healthy Volunteers at 3T

Psychotropic Drugs Effects

United States
Massachusetts General Hospital
Beth Israel Deaconess Medical Center; Mclean Hospital

Completed

Effects of Eszopiclone on Sleep and Memory in Schizophrenia

Schizophrenia

United States
Beth Israel Deaconess Medical Center
Harvard University; Mclean Hospital

Completed

Using Transcranial Magnetic Stimulation (TMS) to Understand 'Negative' Symptoms of Schizophrenia

Schizophrenia | Schizo Affective Disorder | Negative Type; Schizophrenic

United States
University of Minnesota
AstraZeneca; University of Iowa; Mclean Hospital

Completed

Seroquel Extended Release (XR) for the Management of Borderline Personality Disorder (BPD)

Borderline Personality Disorder

United States
Cambridge Health Alliance
Stanley Medical Research Institute; Mclean Hospital

Terminated

Taurine in Adolescents With Bipolar Disorder

Bipolar Disorder

United States
Medical University of South Carolina
Columbia University; Mclean Hospital

Completed

Acamprosate in Alcoholics With Comorbid Anxiety or Depression

Alcohol Dependence | Generalized Anxiety Disorder | Major Depression | Social Anxiety Disorder

United States
Boston Children's Hospital
Massachusetts General Hospital; Massachusetts Institute of Technology; Mclean...

Withdrawn

Brain-imaging and Adolescent Neuroscience Consortium (BANC)

Alcohol Abuse

United States
Brigham and Women's Hospital
Beth Israel Deaconess Medical Center; Mclean Hospital

Not yet recruiting

Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans

Obesity | Appetitive Behavior

United States
Mclean Hospital
National Institute of Mental Health (NIMH); Massachusetts General Hospital

Completed

An Investigation of Early Life Stress and Depression

Major Depressive Disorder (MDD) | History of Childhood Sexual Abuse (CSA)

United States
Mclean Hospital
United States Department of Defense; NorthShore University HealthSystem

Recruiting

Non-Steroidal Anti-Inflammatory Drug (NSAID) Response and Central Sensitization of Pain in Women With Dysmenorrhea

Dysmenorrhea | Menstrual Pain | Non-steroidal Anti-inflammatory Drug

United States
Mclean Hospital
The Klingenstein Third Generation Foundation; The Dana Foundation

Unknown

Genetic and Neural Predictors of Adolescent Depression

Major Depressive Disorder

United States
Mclean Hospital
The Depressive and Bipolar Disorder Alternative Treatment Foundation

Completed

Multiple Treatment Study Using Low Field Magnetic Stimulation for Bipolar Depression (LFMS)

Bipolar Depression

United States
Mclean Hospital
National Alliance for Research on Schizophrenia and Depression

Unknown

Functional Brain Imaging Study of Response to Repetitive TMS (rTMS) Treatment of Major Depression

Major Depression

United States
Mclean Hospital
National Alliance for Research on Schizophrenia and Depression

Completed

CoQ10 in Geriatric Bipolar Depression (CoQ10)

Bipolar Depression

United States
Massachusetts General Hospital
National Institute on Drug Abuse (NIDA); GlaxoSmithKline; Mclean Hospital

Completed

Effectiveness of GW468816, an NMDA Glycine Site Antagonist, for Prevention of Relapse to Smoking

Nicotine Dependence

United States
Massachusetts General Hospital
National Institute on Drug Abuse (NIDA); GlaxoSmithKline; Mclean Hospital

Completed

Effectiveness of GSK598809, a Selective D3 Antagonist, Added to CBT and NRT for Smoking Cessation and Relapse Prevention

Nicotine Dependence

United States
Boston University Charles River Campus
University of Houston; Mclean Hospital

Completed

Interdisciplinary Study of A Novel Anticonvulsant in Alcoholism

Alcohol Dependence

United States
Mclean Hospital
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Withdrawn

Kudzu Effects on Brain Ethanol Levels: Proton Spectroscopy Assessment (Kudzu MRS)

Cerebral Blood Flow | Alcohol Consumption
Mclean Hospital
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Kudzu Treatment for Alcohol Abuse (KUDZU)

Alcohol Consumption

United States
Brigham and Women's Hospital
National Institute on Drug Abuse (NIDA); Mclean Hospital

Not yet recruiting

Pilot Testing a Novel Remotely Delivered Intensive Outpatient Program for Individuals With OUD

Opioid Use Disorder | Serious Bacterial Infections
Paolo Cassano
North Suffolk Mental Health Association; Mclean Hospital

Completed

Transcranial Laser Therapy for Major Depressive Disorder (ELATED)

Major Depressive Disorder

United States
Brigham and Women's Hospital
Harvard School of Public Health (HSPH); Mclean Hospital

Completed

Effectiveness of Alcohol Interventions Among Tuberculosis (TB) Patients in Tomsk Oblast, Russia (IMPACT)

Tuberculosis | Alcohol Use Disorders

Russian Federation
Riley McLean

Enrolling by invitation

Use of Tranexamic Acid in Reduction of Post-Op Complications in Mohs Micrographic Surgery

Skin Neoplasms

United States
Bielefeld University
Mclean Hospital; University of Konstanz; Shifa International Hospital; Shifa Foundation

Recruiting

Preventing Physical and Emotional Violence by Teachers in Public Schools in Pakistan (ICC-T_Pak)

Violence

Pakistan
Brigham and Women's Hospital
Beth Israel Deaconess Medical Center; Boston Children's Hospital; Mclean Hospital

Recruiting

The Functional Neuroanatomy of the Human Physiological Stress Response (Hypo fMRI)

Hypoglycemia | Physiological Stress

United States
Mclean Hospital
National Association for Research on Schizophrenia and Affective Disorders.

Completed

The Effects of Wellbutrin (Bupropion) on Residual and Cognitive Symptoms in SSRI-treated Depression

Depression | Major Depressive Disorder | Unipolar Depression

United States
Brigham and Women's Hospital
National Center for Research Resources (NCRR); Mclean Hospital; Sunovion

Completed

Sleep Loss and Mechanisms of Impaired Glucose Metabolism

Primary Insomnia

United States
Dr. Linda McLean
Ottawa Hospital Research Institute; The Ottawa Hospital

Enrolling by invitation

Characterisation of Uterine Fibroid Tissue Stiffness

Leiomyoma

Canada
Mclean Hospital
National Alliance for Research on Schizophrenia and Depression; Pfizer

Completed

Magnetic Resonance Imaging Study of Geriatric Depression

Major Depressive Disorder

United States

Clinical Trials Sponsored by Mclean Hospital

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