Clinical Trials Sponsored by Midatech Pharma plc

Total 356 results

1200 Pharma, LLC
Translational Research in Oncology

Recruiting

First in Human Study of UCT-03-008 in Participants With Advanced Solid Tumors

Advanced Solid Tumor

United States
Mayo Clinic
Astellas Pharma Inc; Casimir, LLC

Recruiting

Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine

Mitochondrial Diseases | Mitochondrial Myopathies | Kearns-Sayre Syndrome | Mitochondrial DNA Mutation | Chronic Progressive External Ophthalmoplegia With Myopathy

United States
University of Birmingham
Acerta Pharma, LLC; Bloodwise

Recruiting

A Trial of CHOP-R Therapy, With or Without Acalabrutinib, in Patients With Newly Diagnosed Richter's Syndrome (STELLAR)

Richter Syndrome

United Kingdom
Sucampo Pharma Americas, LLC
Sucampo AG

Completed

Evaluation of the Safety of Lubiprostone in Pediatric Participants Aged ≥ 6 Years to < 18 Years With Functional Constipation

Constipation - Functional

United States
Acerta Pharma BV
Merck Sharp & Dohme LLC

Completed

Study of the Combination of Acalabrutinib (ACP-196) and Pembrolizumab in Advanced Head and Neck Squamous Cell Carcinoma (KEYNOTE147)

Squamous Cell Carcinoma of the Head and Neck

United States
Acerta Pharma BV
Merck Sharp & Dohme LLC

Completed

Study of the Combination of ACP-196 and Pembrolizumab in Subjects With Platinum Resistant Urothelial Bladder Cancer (KEYNOTE143)

Metastatic Urothelial Carcinoma

United States
Carolina Research Professionals, LLC
Astellas Pharma Inc

Completed

Open Label Phase Two Study of Enzalutamide With Concurrent Administration of Radium Ra 223 Dichloride in Castration-Resistant (Hormone-Refractory) Prostate Cancer Subjects With Symptomatic Bone Metastasis

Prostate Carcinoma Metastatic to the Bone

United States
Pharmtechnology LLC
Algorithme Pharma, An Altasciences Company

Completed

Bioequivalence Study of Two Formulations of Telmisartan 80 mg Tablets in Healthy Adult Volunteers Under Fasting State

Bioequivalence

Canada
Merck Sharp & Dohme LLC
AESCA Pharma GmbH

Terminated

Induction of Remission in RA Patients at Low Disease Activity by Additional Infliximab Therapy (Study P04644AM1) (TERMINATED)

Rheumatoid Arthritis
Merz Pharmaceuticals GmbH
LLC Merz Pharma, Russia

Completed

A Study to Evaluate the Superiority, Efficacy and Tolerability of Combination Pantovigar With 2% Minoxidil vs 2% Minoxidil in Women With Female Pattern Hair Loss

Female Pattern Hair Loss | Androgenetic Alopecia (AGA) | Ludwig Type 1 | Ludwig Type 2

Russian Federation
Denver Nephrologists, P.C.
CM&D Pharma Limited

Completed

Salivary Phosphorus and Level of Kidney Function

Chronic Kidney Disease

United States
R-Pharm International, LLC
Data Management 365; K-Research, LLC

Completed

Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection (COVID-19)

COVID-19

Russian Federation
invoX Pharma Limited
Merck Sharp & Dohme LLC

Recruiting

FS120 Phase 1/1b Study in Patients With Advanced Malignancies

Metastatic Cancer | Advanced Cancer

Spain, United States
IGC Pharma LLC

Completed

Study of IGC-AD1 in Subjects With Dementia Due to Alzheimer's Disease

Dementia of Alzheimer Type

Puerto Rico
Merz Pharmaceuticals GmbH
LLC Merz Pharma, Russia

Completed

Local Study of Akatinol Memantine in VaD in Russia (MIND)

Vascular Dementia

Russian Federation
Mayne Pharma International Pty Ltd
bioRASI, LLC

Completed

A Clinical Endpoint Bioequivalence Study to Assess Efficacy and Safety of Ivermectin 0.5% Lotion in the Treatment of Head Lice

Head Lice

United States
Mayne Pharma International Pty Ltd
bioRASI, LLC

Completed

Bio-equivalence Study Comparing Permethrin Cream, 5% With Elimite in Patients With Active Scabies.

Scabies

United States
Acerta Pharma BV
Merck Sharp & Dohme LLC

Completed

ACP-196 Alone and in Combination With Pembrolizumab in Subjects With Advanced or Metastatic Pancreatic Cancer (KEYNOTE144)

Metastatic Pancreatic Cancer

United States
Acerta Pharma BV
Merck Sharp & Dohme LLC

Completed

Acalabrutinib (ACP-196) Alone and in Combination With Pembrolizumab in Ovarian Cancer (KEYNOTE191)

Ovarian Cancer

United States
Merck Sharp & Dohme LLC
Essex Pharma GmbH

Completed

The Efficacy and Safety of Pegylated Liposomal Doxorubicin Compared With Capecitabine as First Line Chemotherapy for Metastatic Breast Cancer (P04445/MK-2746-071)

Breast Cancer
Merck Sharp & Dohme LLC
AESCA Pharma GmbH

Terminated

Safety and Tolerability of Low-Dose Temozolomide During Whole Brain Radiation in Patients With Cerebral Metastases From Non-Small-Cell Lung Cancer (Study P04071)(TERMINATED)

Carcinoma, Non-Small-Cell Lung
MEI Pharma, Inc.
SCRI Development Innovations, LLC

Completed

Dose Escalation Study of the Safety and Pharmacokinetics of ME-344 Single Agent for Refractory Solid Tumors (ME-344-001)

Solid Tumors

United States
Chinese PLA General Hospital
Roche Pharma AG

Completed

Intrapleural Bevacizumab and Cisplatin Therapy for Malignant Pleural Effusion Caused by Non-small Cell Lung Cancer

Malignant Pleural Effusion

China
Denver Nephrologists, P.C.
CM&D Pharma, LTD

Completed

Phosphate Binding of Chitosan Chewing Gum in Patients With Chronic Kidney Disease (CKD)

Chronic Kidney Disease

United States
Denver Nephrologists, P.C.
CM&D Pharma Limited

Completed

Double Blind Randomized Placebo Controlled Trial of FOSTRAP Chewing Gum in Patients With CKD and Hyperphosphatemia

Chronic Kidney Disease | Hyperphosphatemia

United States
TME Pharma AG
Merck Sharp & Dohme LLC

Not yet recruiting

Olaptesed With Pembrolizumab and Nanoliposomal Irinotecan or Gemcitabine/Nab-Paclitaxel in MSS Pancreatic Cancer (OPTIMUS)

Metastatic Pancreatic Cancer
Acerta Pharma BV
Merck Sharp & Dohme LLC

Active, not recruiting

ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies (KEYNOTE145)

Multiple Myeloma | Hodgkin Lymphoma | Waldenström Macroglobulinemia | Burkitt Lymphoma | Small Lymphocytic Lymphoma (SLL) | Hairy Cell Leukemia | CLL | Mantle Cell Lymphoma (MCL) | Follicular Lymphoma (FL) | Richter's Syndrome | Indolent Non Hodgkin Lymphoma | Marginal Zone Lymphomas | Mediastinal Large B Cell...

United States
Lille Catholic University
Horizon Pharma Rheumatology LLC

Completed

Study of the Correlation Between UltraSonography and Dual-Energy Computed Tomography Assessment of Urate Deposit (GOUT)

Gout

France
Sucampo Pharma Americas, LLC
Sucampo AG

Completed

Lubiprostone in Children With Functional Constipation

Constipation - Functional

United States, United Kingdom, Canada, Netherlands, Poland, Belgium, France
TME Pharma AG
Merck Sharp & Dohme LLC

Completed

Olaptesed (NOX-A12) Alone and in Combination With Pembrolizumab in Colorectal and Pancreatic Cancer (Keynote-559)

Metastatic Colorectal Cancer | Metastatic Pancreatic Cancer

Germany
Acerta Pharma BV
Merck Sharp & Dohme LLC

Completed

Pembrolizumab Alone and In Combination With Acalabrutinib (ACP-196) in Subjects With Advanced Non-small Cell Lung Cancer (KEYNOTE166)

Carcinoma, Non-Small-Cell Lung

United States
Merck Sharp & Dohme LLC
MDS Pharma Services

Completed

A Study to Determine the Activity of Caelyx With Trastuzumab and Docetaxel in the Treatment of Metastatic Breast Cancer (Study P03679)

Breast Neoplasm
MEI Pharma, Inc.
SCRI Development Innovations, LLC

Terminated

ME-344 Given in Combination With Hycamtin® in Patients With Solid Tumors

Solid Tumors

United States, United Kingdom
Merz Pharmaceuticals GmbH
LLC Merz Pharma, Russia

Completed

Treatment With Xeomin Versus Botox in Children With Spastic Equine and Equinovarus Foot Deformation in Pediatric Cerebral Palsy (XEBEC)

Cerebral Palsy | Spastic Paraplegia and Hemiparesis | Equine and Equinovarus Foot Deformation

Russian Federation
MEI Pharma, Inc.
SCRI Development Innovations, LLC

Completed

Phase I Dose Escalation Study of the Safety and Pharmacokinetics of ME-143 Single Agent for Refractory Solid Tumors

Solid Tumors

United States
Denver Nephrologists, P.C.
CM&D Pharma Limited

Completed

A Study to Evaluate Chitosan Chewing Gum in Patients With Chronic Kidney Disease

Chronic Kidney Disease

United States
Denver Nephrologists, P.C.
CM&D Pharma Limited

Completed

PD Study to Assess Phosphate Binding Characteristics of K2CG Chewing Gum

Chronic Kidney Disease | Hyperphosphatemia

United States
Planexta, Inc
Pharmaxi LLC

Completed

Measuring Accuracy of Wristband for Registration of ECG RR-Intervals for One Hand, SenceBand in Comparison to Holter

HRV

Ukraine
Medimix Specialty Pharmacy, LLC

Suspended

Efficacy of Novel Drug-combinations for Relief of Psoriasis (ENDURE)

Psoriasis

United States
Medimix Specialty Pharmacy, LLC

Completed

Relieving Vasomotor Symptoms Effectively With Bioidentical Hormone Replacement Therapy: The REVERT Study (REVERT)

Menopause

United States
Astellas Pharma Europe B.V.
World Health Information Science Consultants, LLC

Completed

Short and Long-term Safety of Micafungin and Other Parenteral Antifungal Agents (MYCOS)

Systemic Fungal Infections

United States
Medimix Specialty Pharmacy, LLC

Completed

Topical Compounded Pain Creams And Pain Perception (TOPCAPP) (TOPCAPP)

Pain

United States
Medimix Specialty Pharmacy, LLC

Suspended

Compounded Pain Preparation Absorption Study (ComPASS)

Pain

United States
TcLand Expression S.A.
Premier Research Group plc; Theradis pharma; Medpharmgene, Inc.

Terminated

Validation Study of RA-INF-Dx, a Multigene Molecular Test Used to Predict Non-Response to INfliximab Therapy (PRINT)

Rheumatoid Arthritis

Canada, France, Hungary, Italy, Lithuania, Romania, Slovakia, Spain
Merck Sharp & Dohme LLC
Orion Corporation, Orion Pharma

Recruiting

Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A)

Prostatic Neoplasms, Castration-Resistant

Israel, Taiwan, Australia
Merck Sharp & Dohme LLC
Orion Corporation, Orion Pharma

Recruiting

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

Prostatic Neoplasms | Metastatic Castration-resistant Prostate Cancer (mCRPC)

Australia, Germany, United States, Puerto Rico, Israel, Korea, Republic of, Taiwan, China, Costa Rica, Guatemala, Spain, France, Hong Kong, Portugal, Romania, Chile, Czechia, Hungary, Italy, Sweden, Turkey, United Kingdom, Estonia, Ir... and more
Asahi Kasei Pharma Corporation
Emergent Clinical Consulting, LLC

Terminated

First-In-Human Study of AK1320 Encapsulated Microspheres (AK1320 MS) (ENHANCE)

Spinal Stenosis | Degenerative Spondylolisthesis

Canada
APR Applied Pharma Research s.a.
Lavin Consulting, LLC

Completed

Intravenous Aviptadil for Critical COVID-19 With Respiratory Failure (COVID-AIV)

Acute Lung Injury | Corona Virus Infection | Acute Respiratory Distress Syndrome (ARDS) | Critical COVID-19 With Respiratory Failure

United States
Sucampo Pharma Americas, LLC
Sucampo Pharmaceuticals, Inc.

Completed

Opioid-induced Bowel Dysfunction (OBD) Pivotal Assessment of Lubiprostone (OPAL)

Opioid-induced Bowel Dysfunction

United States, Czechia, Germany, Belgium, Poland, Sweden, United Kingdom
Sucampo Pharma Americas, LLC
Sucampo Pharmaceuticals, Inc.

Completed

Safety and Efficacy of Lubiprostone in Pediatric Patients With Constipation

Constipation

United States

Clinical Trials Sponsored by Midatech Pharma plc

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