Search clinical trials for: CNI

Total 214 results

Croma-Pharma GmbH

Completed

Safety of Hyaluronan Thiomer i.o. Implant During Combined Phacoemulsification - Non Penetrating Deep Sclerectomy

Cataract | Open Angle Glaucoma

Austria
Nantes University Hospital

Terminated

Protocol Calcineurin Inhibitor (CNI) Weaning

Function of Renal Transplant

France
Fondazione Salvatore Maugeri

Completed

Last 3 Months of Life in Home Ventilated Patients

Respiratory Failure

Italy
University of Sao Paulo General Hospital

Completed

Assessing the Prevalence of Metabolic Syndrome in Renal Transplantation

Renal Transplantation | Chronic Renal Failure (CRF)

Brazil
Novartis Pharmaceuticals

Completed

24 Months Follow-up, Two Arm Study to Compare the Cardiovascular Profile in a Regimen With Everolimus + Mycophenolic Acid (MPA) Versus (vs.) a Regimen of CNI+MPA in Maintenance Renal Transplant Recipients (EVITA)

Renal Transplant

Spain
University of Sao Paulo General Hospital

Unknown

Renal Transplantation in the Elderly - nEverOld Study

Renal Transplant Rejection | Graft Failure | Transplant; Failure, Kidney | Chronic Renal Failure (CRF)

Brazil
Centro Nacional de Investigaciones Oncologicas...
Apices Soluciones S.L.; Hospital Universitario de Fuenlabrada; Grupo Hospital...

Completed

Study of Individualized Selection of Chemotherapy in Patients With Advanced Pancreatic Carcinoma According to Therapeutic Targets

Advanced Pancreatic Carcinoma

Spain
Centro Nacional de Investigaciones Oncologicas...
Apices Soluciones S.L.; Hospital Universitario de Fuenlabrada; Grupo Hospital...

Completed

Study of Individualized Therapies Selection for Patients With Metastatic Colorectal Carcinoma According to the Therapeutic

Metastatic Disease | Adenocarcinoma of Rectum | Adenocarcinoma of Colon

Spain
First Affiliated Hospital, Sun Yat-Sen University
Second Affiliated Hospital of Guangzhou Medical University

Unknown

Effect of BM-MSCs in DCD Kidney Transplantation

Kidney Transplantation | Acute Kidney Tubular Necrosis

China
Novartis Pharmaceuticals

Completed

SCHEDULE - Scandinavian Heart Transplant Everolimus de Novo Study With Early Calcineurin Inhibitor (CNI) Avoidance (SCHEDULE)

Renal Function and Chronic Allograft Vasculopathy

Norway, Denmark, Sweden
Heidelberg University
Astellas Pharma Inc

Unknown

Delayed CNI-based Immunosuppression With Advagraf After MELD-based Liver Transplantation (IMUTECT)

Liver Graft Dysfunction

Germany
Novartis Pharmaceuticals

Completed

Preservation of Renal Function in Liver Transplant Recipients With Certican Therapy

Liver Transplantation

Germany, Netherlands, Switzerland, Austria
Novartis Pharmaceuticals

Completed

ASCERTAIN: Assessment of Everolimus in Addition to Calcineurin Inhibitor Reduction in the Maintenance of Renal Transplant Recipients

Renal Transplantation

Switzerland
University of Regensburg

Completed

CNI-free de Novo Protocol in Patients Undergoing Liver Transplantation With Renal Impairment (PATRON07)

End Stage Liver Disease | Impaired Renal Function

Germany
Unity Health Toronto

Completed

The Effects of Dietary Fiber in CKD: A Systematic Review and Meta-analysis

Chronic Kidney Disease
Hoffmann-La Roche

Completed

A Study of CellCept (Mycophenolate Mofetil) Combined With Calcineurin Inhibitors in Liver Transplant Patients.

Liver Transplantation

China
Novartis Pharmaceuticals

Terminated

Comparison of CNI-based Regimen Versus CNI-free Regimen in Kidney Transplant Recipients.

Renal Transplantation

Germany
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Everolimus+EC-MPS After Early CNI Elimination vs EC-MPS +Tacrolimus in Renal Transplant Recipients

Chronic Renal Failure

Israel
University of Regensburg

Completed

Immunosuppression in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma

Hepatocellular Carcinoma

Germany
Novartis Pharmaceuticals

Completed

Pharmacodynamics, Efficacy and Safety of Basiliximab 40 or 80 mg in Combination With Ciclosporine Microemulsion or Everolimus, in Adult Low Risk de Novo Renal Transplant Recipients (IDEALE Study) (IDEALE)

Renal Transplantation

France
University Hospital, Brest
Novartis; Roche Pharma AG; Ministry of Health, France; Genzyme, a Sanofi Company

Completed

mTor-inhibitor (EVERolimus) Based Immunosuppressive Strategies for CNI Minimisation in OLD for Old Renal Transplantation (EVEROLD)

Renal Transplant

France
Ospedale San Raffaele
Juvenile Diabetes Research Foundation

Completed

Calcineurin Inhibitor (CNI)-Free Immunosuppressive Regimen in T1D Patients Receiving Islet Transplantation (ECIT-1)

Type 1 Diabetes

Italy, Switzerland
Pediatric Nephrology of Alabama
Pfizer; The Emmes Company, LLC

Completed

Calcineurin Inhibitor Based Immunosuppression Withdrawal (CNI-W)

Renal Transplant

United States
Novartis Pharmaceuticals

Completed

Progression of Renal Interstitial Fibrosis / Tubular Atrophy (IF/TA) According to Epithelial-mesenchymal Transition (EMT) and Immunosuppressive Regimen (Everolimus Based Versus CNI Based) in de Novo Renal Transplant Recipients (CERTITEM)

Renal Interstitial Fibrosis

France
Josep M Grinyo
Carlos III Health Institute

Completed

Selection of Immunosuppression in Kidney Transplant Recipients Depending on Pre-transplant Donor-specific T-cell Reactivity. (SIRES)

Disorder Related to Renal Transplantation

Spain
Yonsei University

Completed

Safety and Efficacy of the Early Introduction of Everolimus (Certican®) With Low Dose of Cyclosporine in de Novo Kidney Recipients After 1 Month of Transplantation

Planned Kidney Transplantation

Korea, Republic of
St. Joseph's Healthcare Hamilton

Withdrawn

Effectiveness of Conversion to Sirolimus Versus Calcineurin Inhibitor (CNI) Reduction in Renal Transplant Patients With Prostate Cancer

Prostate Cancer

Canada
Shanghai University of Traditional Chinese Medicine

Temporarily not available

Standardization Research of TCM Syndrome Differentiation and Treatment on Advanced Breast Cancer

Breast Cancer | Bone Metastasis
Fundación Renal Iñigo Alvarez De Toledo
Effice Servicios Para la Investigacion S.L.

Terminated

Paricalcitol on Albuminuria, Inflammation and Fibrosis on Proteinuric Chronic Renal Diseases (PALIFE Study) (PALIFE)

Chronic Kidney Disease, Unspecified

Spain
Novartis

Completed

Efficacy and Safety of Everolimus With Enteric-Coated Mycophenolate Sodium (EC-MPS) in a Cyclosporine Microemulsion-free Regimen Compared to Standard Therapy in de Novo Renal Transplant Patients

Renal Transplantation

Switzerland, Germany
Boehringer Ingelheim

Completed

Efficacy and Safety of Pramipexole Compared to Placebo in the Treatment of Restless Legs Syndrome (RLS)

Restless Legs Syndrome

United States
Felipe Atienza
Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III

Completed

Radiofrequency Ablation of Drivers of Atrial Fibrillation (RADAR-AF)

Atrial Fibrillation

Spain
Pfizer

Terminated

Study Comparing Effect On Carotid Atherosclerosis Following Conversion From Tacrolimus To Sirolimus Post-Transplant In Kidney Transplant Patients

Atherosclerosis | Kidney Failure

Canada, United States
TRB Chemedica AG

Completed

Intra-articular Hyaluronan After Arthroscopic Meniscal Surgery

Arthroscopic Meniscal Surgery

Belgium
Novartis Pharmaceuticals

Completed

SOCRATES: Steroid or Cyclosporine Removal After Transplantation Using Everolimus

Renal Transplanted Recipients

Australia
Institut National de la Santé Et de la Recherche...
Assistance Publique - Hôpitaux de Paris; Massachusetts General Hospital; Helsinki... and other collaborators

Unknown

Diagnostic and Prognostic Value of New Biomarkers in Patients With Heart Disease

Heart Failure | Pulmonary Disease | Dyspnea

France
University of California, San Francisco
Genentech, Inc.

Withdrawn

Pilot Trial to Assess Effect of CNI Conversion of Efalizumab on T Reg Cells

Autoimmune Diseases

United States
Pediatric Nephrology of Alabama
Pfizer; The Emmes Company, LLC

Completed

Pediatric Kidney Transplant Study of Sirolimus, Mycophenolate Mofetil, and Corticosteroids vs Calcineurin Inhibitor Based Immunosuppression (CNI-W)

Renal Transplant

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

Study Comparing Sirolimus With Cyclosporine in a Calcineurin Inhibitor (CNI)-Free Regimen in Kidney Transplant Recipients

Kidney Transplant

Spain, Italy, Argentina, Greece, Taiwan, Singapore, United States, Canada, United Kingdom, Chile, South Africa, Hungary, Turkey, Austria, Germany, France, Norway, Australia, Sweden, Portugal, Cyprus
Leiden University Medical Center

Completed

VIP: Vascular Imaging Project. Study on the Progression of Cardiovascular Disease in Renal Transplant Recipients

Cardiovascular Disease

Netherlands
Lawson Health Research Institute

Completed

Low Vision Study Comparing EV Training vs. CCTV for AMD Rehabilitation (AMD)

AMD

Canada
Ferring Pharmaceuticals

Completed

Long-term Study of Semapimod (CNI-1493) for Treatment of Crohn's Disease (CD05)

Crohn's Disease

United States, Netherlands, Israel, Belgium, Germany
Ferring Pharmaceuticals

Terminated

CNI-1493 for Treatment of Moderate to Severe Crohn's Disease (CD02)

Crohn Disease

United States
Rennes University Hospital

Completed

Role of Beta-blockers in the Prevention on the Arisen of a Severe Sepsis (TESS)

Community-Acquired Infections

France
Pontificia Universidad Catolica de Chile

Unknown

Search for Transcriptional Biomarkers in a Conversion Protocol From Calcineurin Inhibitors to Mycophenolate Mofetil (TBCP)

Liver Transplantation | Gene Expression | Immunosuppression Conversion

Chile
Klinikum Wels-Grieskirchen
Genzyme, a Sanofi Company

Completed

Anderson-Fabry Disease in Chronic Kidney Disease Patients Not on Renal Replacement Therapy

Focus of Study: Prevalence of Fabry Disease in CKD Population

Austria
pico-tesla Magnetic Therapies, LLC

Unknown

Study of the Application of Magnetic Fields for the Treatment of Parkinson's Disease

Quality of Life | Parkinson's Disease

United States
Rabin Medical Center

Completed

Everolimus and Low Dose CNI Compared With MMF and Full CNI Dose in Heart Transplanted Patients: One Year Follow up (CRAD001AILO2)

Chronic Rejection of Cardiac Transplant

Israel
University of Regensburg
Novartis Pharmaceuticals

Unknown

CNI-free "Bottom"-up Immunosuppression in Patients Undergoing Liver Transplantation (BUILT_01)

Liver Transplantation | Renal Impairment | Everolimus

Germany
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Of The Safety And Efficacy Of Conversion From A CNI To Sirolimus In Renally-Impaired Heart Transplant Recipients

Graft Rejection | Kidney Failure

United States, Spain, Canada, Switzerland, Austria, Australia, New Zealand

Search clinical trials for: CNI

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