Search clinical trials for: Drug Interactions

Total 260212 results

National Institute of Allergy and Infectious Diseases...

Completed

Safety and Tolerance of Zidovudine With Probenecid and the Effect of Probenecid on Zidovudine Pharmacokinetics Over Four Weeks

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluation of the Interaction Between Acetaminophen and Zidovudine

HIV Infections

United States
Shionogi

Completed

Evaluation of Safety, Tolerability, Pharmacokinetics, Drug-Drug and Food Interactions of Single and Multiple Doses of S-648414 in Healthy Adults

Healthy Volunteer

United States, Japan
National Institute of Allergy and Infectious Diseases...

Completed

Drug Interactions of Amprenavir and Efavirenz, in Combination With a Second Protease Inhibitor, in HIV-Negative Volunteers

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Interactions Between HIV Protease Inhibitors and Calcium Channel Blockers

Cardiovascular Diseases | HIV Infections | Hypertension

United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Schering-Plough

Completed

The Safety and Effectiveness of Interferon Alfa-2B Plus Didanosine in Patients With Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States, Puerto Rico
Eisai Co., Ltd.

Completed

A Study to Assess the Effect of Food Intake and Drug-drug Interactions of E7090 When Co-administered With Rabeprazole or Rifampin in Healthy Participants

Healthy Participants

Japan
National Institute of Allergy and Infectious Diseases...
AIDS Clinical Trials Group

Completed

Drug Interactions Between Lopinavir/Ritonavir and Oral or Patch Contraceptives in HIV Infected Women

HIV Infections | Pregnancy

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
National Institute of Mental Health (NIMH)

Withdrawn

Safety, Tolerability, Drug Interactions, and Antiviral Activity of Rilpivirine in Antiretroviral-Naive HIV-Infected Children Less Than 12 Years of Age

HIV Infections
National Institute of Allergy and Infectious Diseases...

Completed

Effect of Fluconazole, Clarithromycin, and Rifabutin on the Pharmacokinetics of Sulfamethoxazole-Trimethoprim and Dapsone and Their Hydroxylamine Metabolites

HIV Infections | Bacterial Infections | Mycoses

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study on Possible Interactions Between Protease Inhibitors (Anti-HIV Drugs) and Drugs Which Lower the Level of Fat in Your Blood

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Novum

Completed

A Study of Chemotherapy Plus ddI or ddC in the Treatment of AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
National Institute of Allergy and Infectious Diseases...

Completed

The Effects of Staggered Dosing on Interactions Between Paired Combinations of Nelfinavir, Ritonavir, and Saquinavir

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluation of the Interaction Between High Dose Sulfamethoxazole/Trimethoprim and Zidovudine

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; ICN Pharmaceuticals

Completed

A Phase I Open-Label Study of the Safety, Tolerance, and Pharmacokinetic Interactions of Combination Didanosine and Ribavirin in HIV-Positive Individuals

HIV Infections

United States
University of British Columbia

Withdrawn

Study of the Effects of Pantoprazole on Levels of Prescribed Psychiatric Medications (PK-PPI)

Psychotic Disorders | Gastroesophageal Reflux

Canada
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

A Study to Investigate the Drug-drug Interactions (DDIs) Between SKLB1028 and Midazolam in Healthy Subjects

Healthy Subjects

China
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Active, not recruiting

A Study to Investigate the Drug-drug Interactions (DDIs) of SKLB1028 With Itraconazole, Gemfibrozil or Rifampicin in Healthy Subjects

Healthy Subjects

China
Daewoong Pharmaceutical Co. LTD.

Completed

To Evaluate Drug-drug Interactions Between DWN12088 and Pirfenidone or Nintedanib in Healthy Volunteers

Idiopathic Pulmonary Fibrosis

Korea, Republic of
Yale University
Gilead Sciences

Withdrawn

A Study of the Pharmacokinetic and Pharmacodynamic Interactions Between Bictegravir, Tenofovir Alafenamide and Rifapentine in Healthy Adult Subjects

Tuberculosis | Hiv

United States
Makerere University
University of Turin, Italy; University of Liverpool; European and Developing...

Completed

Drug-drug Interactions Between Remdesivir and Commonly Used Antiretroviral Therapy (RemTLAR)

HIV/AIDS | Ebola

Uganda
Celgene

Completed

A Study to Evaluate Potential Cytochrome P450 and Transporter Protein Interactions With CC-99677

Healthy Volunteer

United Kingdom
Daewoong Pharmaceutical Co. LTD.

Completed

To Evaluate Drug-drug Interactions Between DWN12088 and Nebivolol or Paroxetine in Healthy Volunteers

Idiopathic Pulmonary Fibrosis

Korea, Republic of
Novartis Pharmaceuticals
National Institute on Drug Abuse (NIDA)

Withdrawn

Study to Assess Safety, Tolerability, and Interactions of Cocaine and Oral AFQ056

Cocaine Use Disorder
University of Castilla-La Mancha
Ministerio de Economía y Competitividad, Spain

Completed

Exercise Training Effects on Metabolic Syndrome: Interactions With Medication (METSYND)

Metabolic Syndrome X | Cardiorespiratory Fitness | Exercise Therapy

Spain
Acerta Pharma BV

Completed

A Study to Evaluate Safety, Pharmacokinetics, Pharmacodynamics, Food Effects, and Drug-drug Interactions of ACP-196 in Healthy Participants

Healthy Participants

United States
Emalex Biosciences Inc.
Syneos Health; Nuventra

Terminated

Drug-Drug Interaction Study to Evaluate the Effects of Ecopipam on the Pharmacokinetics of Multiple Substrates

Drug-Interactions

United States
University of Illinois at Chicago
National Institute on Drug Abuse (NIDA)

Completed

Interactions Between Drug Effects and Environments II

Substance-Related Disorders

United States
University of California, San Francisco
San Francisco AIDS Foundation; California HIV/AIDS Research Program

Completed

Study of Truvada for HIV Pre Exposure Prophylaxis Using Daily Directly Observed Therapy to Look at Potential Interactions Between Truvada and Hormone Therapy (I-BrEATHe)

HIV Prevention | Transgender Health

United States
Psychiatric Hospital of the University of Basel

Completed

Probiotic Supplementation in Severe Depression

Severe Depression

Switzerland
University of Zurich
University Hospital, Zürich; Center of Competence Multimorbidity, Zurich

Completed

Therapeutic Conflicts and Multimorbidity

Diabetes Complications | Gastrointestinal Hemorrhage | Multimorbidity

Switzerland
Cambridge University Hospitals NHS Foundation Trust
AstraZeneca; University of Cambridge

Terminated

A Study of the Pharmacokinetic and Pharmacodynamic Responses in Healthy and Altered Human Cardiovascular Systems (PRIME)

Drug-Related Side Effects and Adverse Reactions | Cardiovascular System Disease

United Kingdom
Yale University

Completed

Functional Neuroimaging of Alcoholism Vulnerability (PIT) (CTNA)

Healthy

United States
Bayer

Completed

Study to Learn the Effect of Drug BAY1817080 on the Way the Body Absorbs, Distributes and Excretes Another Drug Rosuvastatin in Healthy Adult Participants

Drug Interactions

United States
Indiana University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Bridging Pediatric and Adult Biomarkers in Graft-Versus-Host Disease

Graft-Versus-Host Disease

United States
Hospital Italiano de Buenos Aires

Completed

Drug Interactions and Hip Fracture Risk in Older Adults

Hip Fractures

Argentina
Bayer

Completed

Study in Healthy Adult Male Participants to Gather Information How the Human Body Absorbs, Distributes and Excretes the Study Drug Selitrectinib Including the Effect of the Interaction of Food With the Study Drug on the Human Body

Solid Tumors Harboring NTRK Fusion

Germany
Hanlim Pharm. Co., Ltd.

Unknown

The Study of Pharmacokinetic Interactions Between HL237 and Tacrolimus

Healthy Male Volunteers

Korea, Republic of
I.M. Sechenov First Moscow State Medical University

Completed

Direct and Cross Effects of Adaptation to Systemic Hyperthermia: Impact on Quality of Life, Neurohormonal and Psychophysiological Human Status

Quality of Life | Metabolic Disturbance | Exercise Tolerance | Hypoxia, Altitude

Russian Federation
GlaxoSmithKline

Completed

A Cross-over Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics (PK) of GSK525762 in Healthy Female Subjects of Non Child Bearing Potential

Neoplasms | Drug Interactions

United States
Addpharma Inc.

Completed

Evaluating the Pharmacokinetic Interactions and Safety Between AD-2111 and AD-2112

Pain

Korea, Republic of
University Hospital Inselspital, Berne
Bayer

Completed

Rivaroxaban Hypericum Trial

Drug Interaction Study

Switzerland
Boryung Pharmaceutical Co., Ltd

Completed

A Study to Evaluate Drug-drug Interactions Between BR9006-1 and BR9006-2 in Healthy Male Volunteers.

Overactive Bladder | Benign Prostatic Hyperplasia (BPH)

Korea, Republic of
University of Pittsburgh
National Institute on Drug Abuse (NIDA)

Completed

CRF - Nociceptin Receptor Interactions

Healthy

United States
Penn State University

Withdrawn

Iron Status, Maternal Depressive Symptoms, and Mother-child Interactions (IDinteract)

Iron Deficiency Anemia
Radboud University Medical Center
Merck Sharp & Dohme LLC

Completed

Pharmacokinetic Study on Raltegravir and Lamotrigine (GRANOLA)

HIV Infection

Netherlands
Thomas Jefferson University
University of Illinois at Chicago; University of California, San Francisco; Nova... and other collaborators

Completed

The Incidence and Severity of Drug Interactions Before and After Switching Antiretroviral Therapy to Bictegravir/Emtricitabine/Tenofovir Alafenamide in Treatment Experienced Patients

HIV/AIDS

United States
F-star Therapeutics, Inc.
PRA Health Sciences

Completed

A Fixed-Sequence, Drug-Drug Interaction Study Between Multiple Oral Doses of Inarigivir Soproxil and a Single Oral Dose of Midazolam in Healthy Subjects

Drug Interaction Potentiation

Netherlands
Centro De Investigación Y De Estudios Avanzados...
Centro de Estudios Cardiometabólicos S.C. (CESCAM); Inulina y Miel de Agave...

Completed

Gastrointestinal Tolerability to Agavins and Impact on Host-gut Microbiota-metabolism Interactions Modulation

Healthy | Obesity

Mexico
Pfizer

Completed

Study to Evaluate the Effect of Repeat-Dose Rifampin on the Pharmacokinetics (PK) of PF-06651600

Healthy Volunteers

Belgium

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