Drug Interactions and Hip Fracture Risk in Older Adults

January 29, 2021 updated by: CRISTINA MARIA ELIZONDO, Hospital Italiano de Buenos Aires
Older people are in great risk of hip fracture for multiple reasons. Also they often are on medications for medical conditions. Hip fracture risk increases in relation to some medications. When older peoples take 2 or more medications they are in increase risk of hip fracture.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

In this study the investigators describe medication intake profile and identify older people risk of hip fracture in relation to their medication when they are taken together.

Study Type

Observational

Enrollment (Actual)

9721

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

    • Buenos Aires
      • Caba, Buenos Aires, Argentina, 1199
        • Hospital Italiano de Buenos Aires

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

64 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

cases:

  • Affiliated patients to the HMO Plan de Salud Hospital Italiano at least 6 months affiliated.
  • older than 64 years old. affiliated between 01/07/2014 al 31/12/2019.
  • traumatic hip fracture. controls:
  • Affiliated patients to the HMO Plan de Salud Hospital Italiano at least 6 months affiliated. * older than 64 years old.
  • affiliated between 01/07/2014 al 31/12/2019.
  • without traumatic hip fracture.

Description

Inclusion Criteria:

* Affiliated patients to the HMO Plan de Salud Hospital Italiano at least 6 months affiliated.

older than 64 years old

* affiliated between 01/07/2014 al 31/12/2019.

Exclusion Criteria:

  • Pathological Hip fracture
  • bilateral elective hip replacement previous study period

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Cases with hip fracture
Patients afiliated to a HMO Plan de Salud Hospital Italiano who presented hip fracture between 2014 and 2019
when two drugs are taken together
controls without hip fracture
Patients afiliated to a HMO Plan de Salud Hospital Italiano without hip fracture between 2014 and 2019
when two drugs are taken together

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
hip fracture
Time Frame: 1 year
non pathological hip fracture
1 year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

August 16, 2018

Primary Completion (Actual)

November 25, 2020

Study Completion (Actual)

December 30, 2020

Study Registration Dates

First Submitted

January 26, 2021

First Submitted That Met QC Criteria

January 26, 2021

First Posted (Actual)

February 1, 2021

Study Record Updates

Last Update Posted (Actual)

February 2, 2021

Last Update Submitted That Met QC Criteria

January 29, 2021

Last Verified

January 1, 2021

More Information

Terms related to this study

Other Study ID Numbers

  • 3804

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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