Search clinical trials for: Inhaled

Total 1385 results

Imperial College London

Completed

Measuring Hydrogen Peroxide in Exhaled Breath Condensate in HV

Proof Of Concept Study

United Kingdom
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of the Efficacy and Safety of MK-5475 in Participants With Pulmonary Arterial Hypertension (INSIGNIA-PAH: Phase 2/3 Study of an Inhaled sGC Stimulator in PAH) (MK-5475-007)

Pulmonary Arterial Hypertension | Hypertension, Pulmonary

United States, Argentina, Australia, Belgium, Canada, Colombia, France, Germany, Greece, Israel, Italy, Mexico, New Zealand, Poland, Russian Federation, Sweden, Turkey, United Kingdom
Sedana Medical

Active, not recruiting

Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensive Care Unit Adult Patients (INSPiRE-ICU2) (INSPiRE-ICU2)

Sedation

United States
Galecto Biotech AB
Syneos Health; bioRASI, LLC

Completed

A Study to Test the Efficacy and Safety of Inhaled GB0139 in Subjects With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis (IPF)

United States, Spain, Israel, France, United Kingdom, Russian Federation, Australia, Italy, Germany, Canada, Belgium, Georgia, Ireland, Poland, Ukraine
University of Edinburgh
NHS Lothian

Completed

The Role of Eicosanoids in the Cardiovascular Actions of Inhaled Nanoparticles (ECOARM)

Healthy Volunteers | Vasodilation | Lung Function | Blood Biomarkers | Blood Clotting

United Kingdom
Organon and Co

Completed

Study of Mometasone Furoate/Formoterol Combination and Fluticasone/Salmeterol in Persistent Asthmatics Previously Treated With Inhaled Glucocorticosteroids (P04139)

Asthma
Organon and Co

Completed

Study of Inhaled Glucocorticosteroids/Long-Acting Bronchodilator Drugs in Subjects With Asthma That Have Been Taking Inhaled Glucocorticosteroids (Study P04705AM1)

Asthma
AstraZeneca

Active, not recruiting

BURAN: Benralizumab on Airway Dynamics in Severe Eosinophilic Asthma Using Functional Respiratory Imaging (BURAN)

Asthma

United States, Belgium, United Kingdom, France, Portugal, Australia, Spain
InCarda Therapeutics, Inc.

Completed

INhalation of Flecainide to Convert Recent Onset SympTomatic Atrial Fibrillation to siNus rhyThm (INSTANT) (INSTANT)

Paroxysmal Atrial Fibrillation (PAF)

Netherlands, Belgium
Organon and Co

Completed

Montelukast in Mild Asthmatic Children With Allergic Rhinitis (0476-367)

Asthma | Allergic Rhinitis
Xijing Hospital

Completed

Inhaled NO in Surgical Patients With Recent COVID-19 Infection (INORDINATE)

COVID-19 | Postoperative Complications | Surgery | Nitric Oxide

China
Organon and Co

Completed

Study of Inhaled Corticosteroid Plus Montelukast Compared With Inhaled Corticosteroid Therapy Alone in Patients With Chronic Asthma (0476-386)

Asthma
Organon and Co

Completed

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Inhaled Montelukast (MK-0476) in Participants With Mild or Moderate Asthma (MK-0476-380 AM3)(COMPLETED)

Asthma
AstraZeneca

Active, not recruiting

Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations (RESOLUTE)

Chronic Obstructive Pulmonary Disease

United States, Austria, Canada, Denmark, Germany, Italy, Spain, United Kingdom, Belgium, Vietnam, Brazil, Hungary, Philippines, China, Korea, Republic of, Argentina, Australia, Poland, Turkey, Japan, Greece, Netherlands, Czechia, Mexico, Bulgar... and more
University of Florida

Withdrawn

The ARCTIC Trial: Aerosolized Inhaled Adenosine Treatment in Patients With Acute Respiratory Distress Syndrome (ARDS) Caused by COVID-19

Acute Respiratory Distress
University of California, Davis
Beekley Medical

Completed

Aromatherapy for Management of Pain, Anxiety, and Nausea in the Acute Care Setting

Effectiveness of Aromatherapy

United States
Sedana Medical

Active, not recruiting

Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensive Care Unit Adult Patients (INSPiRE-ICU1) (INSPiRE-ICU1)

Sedation

United States
Receptor Life Sciences
The Epilepsy Study Consortium

Terminated

Safety, Tolerability, and Efficacy of RLS103 in a Clinical Model of Photosensitive Epilepsy

Epilepsy

United States
University of California, San Diego

Suspended

Dose-Ranging Trial of Inhaled Cannabis for Acute Migraine Treatment

Migraine | Cannabis | THC

United States
AstraZeneca

Completed

Efficacy and Safety Study of Benralizumab in Patients With Uncontrolled Asthma on Medium to High Dose Inhaled Corticosteroid Plus LABA (MIRACLE)

Asthma

Taiwan, Korea, Republic of, Philippines, China
Chiesi Farmaceutici S.p.A.

Active, not recruiting

A Study Testing the Superiority of CHF 1535 pMDI 800/24µg Total Daily Dose Compared to CHF 718 pMDI 800µg Total Daily Dose in Adults With Asthma on Medium or High-Dose Inhaled Corticosteroid (FORCE2)

Asthma

United States
Erik Allen Jensen
University of Florida

Active, not recruiting

Inhaled Tobramycin in BPD

Bronchopulmonary Dysplasia

United States
Parc de Salut Mar

Active, not recruiting

Asthma Research in Children and Adolescents (ARCA)

Asthma in Children | Persistent Asthma | Asthma Exacerbation

Spain
Imperial College London

Withdrawn

Inhaled Mannitol and Ciliary Beat Frequency in COPD Patients

Chronic Obstructive Pulmonary Disease

United Kingdom
Dr. Denis O'Donnell
Queen's University; Ontario Lung Association

Completed

Differential Mechanisms of Dyspnea Relief in Advanced COPD: Opiates vs. Bronchodilators

Chronic Obstructive Pulmonary Disease

Canada
Dr. Denis O'Donnell

Completed

The Effect of Inhaled Nitric Oxide on Deadspace in COPD

Chronic Obstructive Pulmonary Disease

Canada
Dr. Denis O'Donnell
Boehringer Ingelheim

Completed

Nebulized Fentanyl in Patients With Mild to Moderate Interstitial Lung Disease and Chronic Dyspnea

Interstitial Lung Disease

Canada
Dr. Denis O'Donnell

Completed

Inhaled Nitric Oxide (iNO) in Post-Pulmonary Embolism (Post-PE)

Pulmonary Embolism | Dyspnea

Canada
Pulmatrix Inc.

Terminated

Study to Evaluate Itraconazole Administered as Inhaled Dry Powder in Adults With Asthma and ABPA

ABPA

Australia, United States, United Kingdom, France
Duke University
Actelion

Terminated

Outpatient Vasodilator Assessment Using Iloprost in Pulmonary Hypertension (OVATION)

Pulmonary Hypertension

United States
Receptor Life Sciences

Withdrawn

Safety, Tolerability, and Efficacy of RLS103 in Subjects With Acute Anxiety Within Social Anxiety Disorder (SAD)

Social Anxiety Disorder

United States
Boehringer Ingelheim

Completed

Exacerbation Risk in Asthma

Asthma

United States
Sanofi
Regeneron Pharmaceuticals

Active, not recruiting

Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate to Severe COPD With Type 2 Inflammation (NOTUS)

Chronic Obstructive Pulmonary Disease

Greece, Belgium, Spain, Argentina, Hungary, South Africa, United Kingdom, France, Latvia, Germany, Netherlands, Russian Federation, Ukraine, United States, Australia, Brazil, Bulgaria, Canada, Chile, Colombia, Czechia, Lithuania, Me... and more
Vectura, Inc.
Syneos Health

Completed

Study to Compare the Pharmacodynamics and Pharmacokinetics of Acetylsalicylic Acid Powder for Oral Inhalation With Non-enteric-coated Chewable Aspirin in Healthy Adults.

Healthy Volunteers

United States
Vectura, Inc.
Syneos Health

Terminated

Study to Compare the Pharmacokinetics and Pharmacodynamics of ASA Powder for Oral Inhalation With Non-enteric-coated Chewable Aspirin in Adult Subjects With Obstructive or Restrictive Pulmonary Function

Obstructive Pulmonary Function | Restrictive Pulmonary Function

United States
Ottawa Hospital Research Institute
Mayday Fund

Enrolling by invitation

Prehospital Inhaled Methoxyflurane Non-Clinical Occupational Exposure Study

Occupational Exposure

Canada
Bond Avillion 2 Development LP
Parexel

Active, not recruiting

A Comparison of PT027 vs PT007 Used as Needed in Participants With Asthma

Asthma

United States
Menoufia University

Active, not recruiting

Inhaled Versus Intravenous Milrinone for Patients Undergoing Mitral Valve Replacement Surgery

Pulmonary Hypertension | Mitral Valve Replacement | Inhaled Milrinone | Intravenous Milrinone

Egypt
University of Washington, the Collaborative Health...
Cystic Fibrosis Foundation

Completed

Saline Hypertonic in Preschoolers + CT (SHIP-CT)

Cystic Fibrosis

Spain, United States, Australia, Italy, France, Canada, Belgium, Denmark, Netherlands
Tomsk National Research Medical Center of the Russian...

Completed

High-dose Inhaled NO Therapy for the Prevention of Nosocomial Pneumonia After Cardiac Surgery With CPB

Nosocomial Pneumonia

Russian Federation
Mannkind Corporation
Jaeb Center for Health Research

Active, not recruiting

Afrezza® INHALE-1 Study in Pediatrics (INHALE-1)

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate-to-severe COPD With Type 2 Inflammation (BOREAS)

Chronic Obstructive Pulmonary Disease

Spain, Argentina, China, Mexico, Canada, Ukraine, Israel, Italy, Czechia, Korea, Republic of, Bulgaria, Chile, Denmark, Finland, Germany, Hungary, Japan, Poland, Romania, Russian Federation, Slovakia, Sweden, Turkey, United States
Australian National University
St Vincent's Hospital Melbourne; The George Institute; Royal North Shore Hospital and other collaborators

Withdrawn

Inhaled Heparin for Hospitalised Patients With Coronavirus Disease 2019 (COVID-19) (INHALE-HEP)

COVID-19

Australia
Third Pole Therapeutics, Inc.

Active, not recruiting

Early Feasibility Study Evaluating the 3P-100 Device in Subjects With PH-ILD (EFS)

Hypertension, Pulmonary | Lung Diseases, Interstitial

United States
Mannkind Corporation
Jaeb Center for Health Research

Active, not recruiting

INHALE-3: Afrezza® Combined With Insulin Degludec Versus Usual Care in Adults With Type 1 Diabetes

Diabetes Mellitus, Type 1

United States
Chinese University of Hong Kong

Completed

HIV Pre-exposure Prophylaxis Implementation Hong Kong Study

HIV Infections

Hong Kong
University of North Carolina, Chapel Hill
National Institute of Environmental Health Sciences (NIEHS)

Completed

A Study of Gamma Tocopherol-enriched Supplement on Lower Airway Responses to Inhaled Wood Smoke in Healthy Adults (SmokeyT)

Asthma | Airway Inflammation

United States
AstraZeneca
Iqvia Pty Ltd; Premier Inc.

Withdrawn

IKANOS: Breztri Maintenance Versus Any Non-Triple Inhaled Therapy After Hospitalization for a COPD Exacerbation in the US (IKANOS)

COPD

United States
Armata Pharmaceuticals, Inc.
Cystic Fibrosis Foundation

Completed

Ph 1/2 Study Evaluating Safety and Tolerability of Inhaled AP-PA02 in Subjects With Chronic Pseudomonas Aeruginosa Lung Infections and Cystic Fibrosis (SWARM-Pa)

Cystic Fibrosis | Pseudomonas Aeruginosa | Lung Infection | Pseudomonas | Lung Infection Pseudomonal

United States
Prof. Dr. Jörg Leuppi

Terminated

Inhaled Aviptadil for the Treatment of COVID-19 in Patients at High Risk for ARDS

Covid19 | Corona Virus Infection | ARDS | Aviptadil

Switzerland

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