Search clinical trials for: Nasal Allergen Challenge

Total 5986 results

GlaxoSmithKline

Completed

Study to Evaluate GSK2190915 in Subjects With Mild Asthma

Asthma

United Kingdom
Universitair Ziekenhuis Brussel

Completed

The Challenge of Obtaining Qualitative Bacterial Cultures in Non-expectorating Cystic Fibrosis Patients

Cystic Fibrosis
Stallergenes Greer

Completed

Efficacy and Safety of Sublingual Tablets of Grass Pollen Allergen Extract

Seasonal Allergic Rhinitis

Austria
University of Saskatchewan

Completed

Airway Response to Repeat Allergen Challenge and the Effect of Ibuprofen in Mild Atopic Asthma

Atopic Asthma

Canada
AstraZeneca

Completed

The Tolerability and Effects of AZD8848 in Allergic Asthma Subjects Challenged With Inhaled Allergen

Allergic Asthma

United Kingdom
Axikin Pharmaceuticals, Inc.

Completed

A Phase IIa Repeat Dose AXP1275 vs Placebo Cross-over Trial With Pulmonary Allergen Challenge in Adults With Asthma

Atopic Asthma

Canada
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Evaluate the Effectiveness of JNJ 40929837 for the Treatment of Asthma Using a Bronchial Allergen Challenge Model

Asthma

Germany, United Kingdom
Merck Sharp & Dohme LLC

Withdrawn

A Single-Dose Study of MK-8351 in a Lung Allergen Challenge (MK-8351-003)

Asthma
AstraZeneca

Completed

The Study Will Evaluate the Efficacy of AZD5423 in Patients With Mild Asthma Challenged With an Inhaled Allergen (Allergen)

Asthma

Canada
Hamilton Health Sciences Corporation
Genentech, Inc.

Completed

Kinetics of IgE Memory B Cells, Plasmablasts and Plasma Cells After Whole Lung Allergen Challenge in Mild Asthmatics

Atopic Asthma

Canada
Alcon Research

Completed

Efficacy and Safety of an Ophthalmic Solution in Patients With Allergic Conjunctivitis

Allergic Conjunctivitis
Alcon Research

Completed

Study of Olopatadine HCl Ophthalmic Solutions Compared to Vehicle Using the Conjunctival Allergen Challenge (CAC) Model of Acute Allergic Conjunctivitis in Japanese Subjects

Allergic Conjunctivitis
Boehringer Ingelheim

Completed

Randomized, Placebo Controlled, Crossover Study in an Environmental Challenge Chamber to Assess Safety & Efficacy of Three Oral Doses of BI 671800 Versus Fluticasone Propionate and Montelukast in Sensitive Seasonal Allergic Rhinitis Patients Out of Season

Asthma | Rhinitis, Allergic, Seasonal

Germany
University of North Carolina, Chapel Hill

Completed

Effect of House Dust Mite Allergen Challenge in Persons Using 1200 mg Gamma Tocopherol Supplements (MiteE)

Allergic Rhinitis | Mild Asthma

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Study of Dust Mite Inhalation in Humans

Allergy | Mild Asthma

United States
Pharmaxis

Completed

Efficacy of TPI ASM8 During a 14-Day Allergen Challenge

Asthma

Canada
Fraunhofer-Institute of Toxicology and Experimental...
Hannover Medical School

Completed

Ex Vivo Effect of Surfactant Protein D on Pulmonary Cells in Patients With Asthma and Pilot Study to Assess Local Inflammation Induced by Segmental Allergen Challenge by Magnetic Resonance Imaging

Mild Intermittent Asthma (Gina 1)

Germany
Regional Oncologic Center
European Organisation for Research and Treatment of Cancer - EORTC; Scandinavian... and other collaborators

Completed

Hormone Replacement Therapy and the Risk of Breast Cancer Recurrence in Women With Previous Early Stage Breast Cancer

Breast Cancer | Menopausal Symptoms

Finland, Norway, Poland, Sweden, Switzerland
John Sundy

Terminated

Differential Gene Expression in Lung and Peripheral Blood After Inhaled Allergen Challenge

Healthy | Atopic Asthma

United States
Alcon Research

Completed

Efficacy and Safety of AL-4943A Ophthalmic Solution in Patients With Allergic Conjunctivitis Using the Conjunctival Allergen Challenge (CAC) Model

Allergic Conjunctivitis
Bayer
Queen's University

Completed

A Randomized, Placebo Controlled Study to Determine the Efficacy and Speed of a Nasal Spray in Allergen Induced Seasonal Allergic Rhinitis (GEYSER)

Seasonal Allergic Rhinitis

Canada
Ono Pharma USA Inc
Ono Pharmaceutical Co. Ltd

Completed

A Placebo and Active Controlled Study of ONO-6950 Following Allergen Challenge in Patients With Asthma

Asthma

Canada
Barbro Dahlen
Karolinska Institutet

Completed

COX-2 Inhibition in Allergic Asthma

Asthma

Sweden
Hamilton Health Sciences Corporation

Completed

Role of Cigarette Smoking in Regulating Allergen-induced Early and Late Responses in Mild Asthmatics

Asthma

Canada
University of South Florida

Completed

Repeated Nasal Challenge in Skin Prick-puncture Negative and Intradermal Positive Dust Mite Allergic Rhinitis Patients (DUSTMITE)

ALLERGIC RHINITIS

United States
Helse Stavanger HF
University Hospital, Akershus

Unknown

Challenge Test for Acetylsalicylic Acid Hypersensitivity

Asthma, Aspirin-Induced | ASA Intolerant Asthma | Asthma Aspirin-sensitive | Asthma, Nasal Polyps, and Aspirin Intolerance

Norway
GlaxoSmithKline

Completed

This Study Will Examine the Effects of GSK256066 to Protect Mild Steroid-naive Asthmatics Against an Antigen Challenge

Asthma

New Zealand
GlaxoSmithKline

Completed

Study To Evaluate GSK256066 In Subjects With Mild Bronchial Asthma

Asthma | Mild Asthma

United Kingdom
Bausch & Lomb Incorporated

Completed

Loteprednol Ophthalmic Base Compared to Loteprednol Ophthalmic Suspension vs Placebo in an Allergen Challenge

Allergic Conjunctivitis

United States
Alcon Research

Withdrawn

To Evaluate the Efficacy of AL-38583 in the Reduction of Tear Eosinophil Count Following Conjunctival Allergen Challenge

Allergic Conjunctivitis
ORA, Inc.

Withdrawn

An Allergen BioCube (ABC) Study Evaluating the Onset of Action of Fluticasone Furoate Nasal Spray and Olopatadine Nasal Spray Compared to Placebo

Allergic Rhinitis
Pfizer

Withdrawn

A Study To Assess The Duration Of Action Of PF-03526299 In Asthmatic Subjects Following Allergen Challenge

Asthma
University of North Carolina, Chapel Hill
National Center for Complementary and Integrative Health (NCCIH)

Completed

In Vitro Basophil Responsiveness to Allergen Challenge After Gamma-tocopherol Supplementation in Allergic Asthmatics (Gammaphil)

Asthma | Allergy | Asthmatic | Allergic

United States
Johann Wolfgang Goethe University Hospital

Completed

Safety and Repeatability of Bronchial Challenge With Grass-pollen

Allergic Asthma

Germany
Vanderbilt University

Completed

A Comparison of Skin Prick Tests, Clinical Symptoms, and Nasal Challenge Using a New Mouse Extract

Mouse Allergies | Mouse Sensitization

United States
Icagen

Completed

Safety and Efficacy Study of Oral Senicapoc on Allergen Challenge in Atopic Asthmatic Subjects

Atopic Asthma

United Kingdom
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Validation of an Environmental Exposure Chamber for Inhalation Studies With House Dust Mite Allergen in Patients With Allergic Rhinitis

Allergy to House Dust Mite

Germany
Gilead Sciences

Completed

Study to Investigate Effects of CAL-263 in Subjects With Allergic Rhinitis Exposed to Allergen in an Environmental Chamber

Allergic Rhinitis

Austria
Novartis
Genentech, Inc.; Tanox

Completed

A Study of Efficacy of New Doses of Xolair to Protect From Allergen Challenge in Groups of Asthma Patients Defined by IgE Levels

Asthma

Germany, Netherlands, South Africa
Palau Pharma S.A.

Completed

Proof of Activity Study of UR-63325 in Allergic Rhinitis Induced by Nasal Challenge

Seasonal Allergic Rhinitis

Germany
Johann Wolfgang Goethe University Hospital

Completed

Evaluation of Bronchial Inflammation in Allergic Bronchopulmonary Aspergillosis (ABPA) (ABPA)

Cystic Fibrosis,

Germany
AstraZeneca

Completed

SMILDA - Symbicort®Turbuhaler® Allergan Challenge Study in Allergic Patients With Mild Asthma

Asthma

Sweden
Pfizer

Completed

A Study To Assess The Effect Of PF-03526299 On Lung Function Following An Allergen Challenge In Asthmatic Subjects

Asthma

United Kingdom
ORA, Inc.

Completed

Conjunctival Allergen Challenge (CAC) Following Allergen Exposure in the Allergen BioCube (ABC) (ABC CAC)

Allergic Rhinoconjunctivitis

United States
Capnia, Inc.

Completed

The Effect of Nasal Carbon Dioxide (CO2) on Nasal Congestion in Subjects With Perennial Allergic Rhinitis

Perennial Allergic Rhinitis

United States
Fraunhofer-Institute of Toxicology and Experimental...
German Research Foundation

Completed

Ex Vivo Effect of Surfactant Protein D on Pulmonary Immune Cells Derived From Bronchoalveolar Lavage After Segmental Allergen Challenge in Patients With Asthma

Asthma

Germany
Siriraj Hospital

Unknown

Optimal Concentration of Dermatophagoides Pteronyssinus (Dp) Allergen Extract for Skin Prick Test (SPT) of Thai Population (DSPT)

Rhinitis, Allergic, Perennial | Rhinitis, Allergic, Seasonal | Skin Prick Test

Thailand
Oxagen Ltd
King's College Hospital NHS Trust; Medicines Evaluation Unit, Manchester, UK

Completed

OC000459 Bronchial Allergen Challenge

Bronchial Asthma

United Kingdom
Pfizer

Completed

A Study To Assess The Effect Of PF-03893787 On Lung Function Following An Allergen Challenge In Asthmatic Subjects

Asthma

United Kingdom
GlaxoSmithKline

Completed

Allergen Challenge Chamber Study With Single Dose Intranasal GSK1004723 Compared With Placebo

Allergic Rhinitis

Germany

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