Search clinical trials for: Normal subjects

Total 24295 results

Ultragenyx Pharmaceutical Inc

Completed

A Study to Assess Plasma Ammonia Time-Normalized Area Under the Curve and Rate of Ureagenesis in Healthy Adult Subjects

Ornithine Transcarbamylase Deficiency

United States
Eisai Inc.
Purdue Pharma LP

Completed

Study to Evaluate the Pharmacokinetics of Lemborexant (E2006) and Its Metabolites in Subjects With Normal Renal Function or With Severe Renal Impairment

Renal Impairment

United States
University of California, Los Angeles

Completed

Study of the Effects of an Antidepressant Medication and Placebo on the Brain Functioning of Normal Subjects

Depression

United States
ObsEva SA

Completed

Safety and Pharmacokinetics of Linzagolix in Female Subjects With Normal and Impaired Renal Function

Renal Impairment | Healthy Participants

United States
Washington University School of Medicine

Completed

Fatty Acid Radiotracer Comparison Study in Heart Failure Patients

Heart Failure | Obesity | Type 2 Diabetes Mellitus | Health Normal Volunteer Subjects

United States
Astellas Pharma Europe B.V.
FibroGen

Completed

A Phase 1 Study of Roxadustat in Subjects With Different Degrees of Renal Function

Impaired Renal Function | Normal Renal Function

Germany, United Kingdom
BioAegis Therapeutics Inc.

Completed

A Phase 1b/2a Study of the Safety and Pharmacokinetics of Rhu-plasma Gelsolin in Hospitalized Subjects With CAP

Community-acquired Pneumonia

Australia, Georgia
ObsEva SA

Completed

Safety and Pharmacokinetics Study of Linzagolix in Female Subjects With Normal and Impaired Hepatic Function

Hepatic Impairment | Healthy Participants

United States
Bausch Health Americas, Inc.

Terminated

Efficacy and Safety of Brodalumab Compared With Placebo and Ustekinumab in Moderate to Severe Plaque Psoriasis Subjects (AMAGINE-3)

Plaque Psoriasis

United States, Belgium, Italy, Hungary, Poland, Australia, France, Greece, Russian Federation, Latvia, Canada
PepsiCo Global R&D
DSM Nutritional Products, Inc.

Completed

The Effect of a Breakfast Meal Containing Oat β-glucan on Food Intake at a Subsequent Meal in Normal-weight and Overweight Subjects

Satiety

Canada
The University of Tennessee, Knoxville
DePuy Synthes

Completed

THA Kinematics and Sound for Subjects for Normal, Diseased and Implanted Hips

Hip Injuries

United States
National Taiwan University Hospital

Unknown

A Health Promotion Project for Workers at National Taiwan University Hospital

Abdominal Obesity Metabolic Syndrome | Subjects With Poor Fitness Status

Taiwan
Idorsia Pharmaceuticals Ltd.

Completed

A Study in Healthy Subjects to Investigate Whether Administration of Lucerastat Can Affect Normal Heart Function

Healthy

Netherlands
Gregory Jicha, 323-5550
University of Kentucky; Kentucky Alzheimer's Center

Completed

Valproic Acid in Subjects With Intact Cognition - Proof of Concept Study (VPA)

Alzheimer's Disease

United States
Neuraly, Inc.

Completed

A Phase 1 Study to Assess the Safety of NLY01 in Healthy Subjects (NLY01-H1)

Safety and Tolerability in Healthy Volunteers

United States
Universitätsmedizin Mannheim

Completed

Multiple Breath Washout (MBW) Using Sulfur Hexafluoride Reference Values and Influence of Anthropometric Parameters

Healthy Subjects | Non-smokers | Smokers
Pfizer

Completed

Glasdegib Renal Impairment Study

Renal Impairment

United States
University of California, San Diego
Forest Laboratories

Completed

Effects of the Beta-blocker Nebivolol (Bystolic) on Subjects With High Normal Blood Pressure and/or a Family History of Hypertension

Hypertension | Pre-hypertension

United States
Chiang Mai University
Health Systems Research Institute, Thailand

Unknown

Chlorhexidine Gluconate Versus Mupirocin Ointment in the Prevention of Peritoneal Dialysis-Related Infection (COSMO-PD)

Peritoneal Dialysis | End Stage Renal Disease

Thailand
GlaxoSmithKline

Terminated

Assessment of the Pharmacokinetics of GSK1278863 and Metabolites in Normal Subjects and Subjects With Renal Impairment

Anaemia

United States
Gustave Roussy, Cancer Campus, Grand Paris

Completed

A Study to Select Rational Therapeutics Based on the Analysis of Matched Tumor and Normal Biopsies in Subjects With Advanced Malignancies (WINTHER)

Metastatic Cancer

France
University of California, Davis

Completed

A Feasibility Study to Determine PET/CT Imaging of Blood Flow to the Bone (PETCT)

Normal Subjects

United States
Novo Nordisk A/S

Completed

Investigation of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Multiple Doses of Somapacitan in Subjects With Mild and Moderate Degrees of Hepatic Impairment Compared to Subjects With Normal Hepatic Function.

Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency

Slovakia
Eye-yon Medical

Completed

Study of Using the Hyper-CL™ Lens (Hyper Osmotic Contact Lens) in Subjects Suffering From Corneal Edema

CORNEAL EDEMA

Israel, Poland
Dynavax Technologies Corporation

Completed

Safety, Pharmacokinetics, and Pharmacodynamics of SD-101 in Healthy Normal Males

Healthy

United States
Astellas Pharma Inc

Completed

Pharmacokinetics Study in Patients With Impaired Renal Function and Subjects With Normal Renal Function

Patients With Impaired Renal Function

Japan
Akebia Therapeutics

Completed

A Single Dose Study of Oral Vadadustat in Subjects With Normal and Impaired Hepatic Function

Hepatic Impairment

United States
University of Wisconsin, Madison
Nephro-Tech 1, LLC

Completed

Evaluation of the Ocular Safety of Calcium Formate in Normal, Healthy Female Subjects

Healthy

United States
Northwell Health

Terminated

In Vivo Anatomy, Physiology, Mechanics and Function of the Lower Esophageal Sphincter

GERD | Barretts Esophagus

United States
Genocea Biosciences, Inc.

Terminated

Maintenance Dose Study of GEN-003 in Subjects With Genital Herpes Infection

Genital Herpes | HSV-2 Infection

United States
SolAeroMed Inc.

Completed

Single Dose Study to Evaluate the Safety, and Efficacy of S-1226 (8%) in Subjects With Mild Atopic Asthma (S-1226(8%))

Asthma

Canada
Ipsen

Completed

Study to Assess the Efficacy of an Extended Injection Interval Schedule of Lanreotide Autogel in Acromegalic Subjects (LEAD)

Acromegaly

France, Brazil, Denmark, Finland, Greece, Korea, Republic of, Latvia, Netherlands, Norway, Poland, Romania, Russian Federation, Serbia, Sweden
Yuhan Corporation

Completed

Clinical Trial of Temisartan/Amlodipine & Rosuvastatin in Subjects With Hypertension and Hyperlipidemia

Hypertension | Hyperlipidemia

Korea, Republic of
Alnylam Pharmaceuticals

Terminated

A Study of an Investigational Drug, ALN-AAT, in Healthy Adult Subjects and Patients With ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease

Antitrypsin Deficiency Liver Disease

United Kingdom
American University of Beirut Medical Center

Completed

Effect of Food Acceptability on Appetite Hormones' Response in Normal Weight vs. Obese Male Subjects

Eating Behavior
Idorsia Pharmaceuticals Ltd.

Completed

A Study in Healthy Subjects to Investigate Whether Administration of Clazosentan Can Affect Normal Heart Function

Healthy Subjects

Netherlands
Yonsei University

Unknown

A Clinical Trial of Silk Peptide for the Evaluation of Efficacy on Immune Function

Normal Healthy Subjects

Korea, Republic of
LG Life Sciences

Completed

Extension Clinical Study to Evaluate the Long-term Efficacy and Safety of Repeat Treatment of YVOIRE Contour Injected Into the Anteromedial Malar Region in Subjects Who Have Completed the LG-HACL014 Study

Normal, Healthy Adults With Moderate, Severe, or Very Severe Volume Loss of Anteromedial Malar Region Who Have Completed the LG-HACL014 Study

Korea, Republic of
University of Colorado, Denver
McCormick Science Institute

Completed

Influence on Food Liking of Adding Spices to Replace Sugar Using CLT

Normal Subjects Who Agree to Participate in Taste Testing
Geropharm

Completed

Fasting Bioequivalence Study of Memantinol 20 mg Tablets Versus Akatinol Memantine® 20 mg Tablets In Normal Healthy Subjects

Bioequivalence, AUC, Cmax, Pharmacokinetics

Russian Federation
Alnylam Pharmaceuticals

Completed

A Safety and Tolerability Study of an Investigational Drug, ALN-TTRSC02, in Healthy Subjects

Transthyretin-mediated Amyloidosis (ATTR Amyloidosis)

United Kingdom
Yonsei University

Completed

A Clinical Trial of Bio-Germanium for the Evaluation of Efficacy on Immune Function (NYG)

Normal Healthy Subjects

Korea, Republic of
Pharmaceutical Project Solutions, Inc.
Cognitive Research Corporation

Completed

Pharmacokinetic Study of Intranasal RX0041-002 in Hepatic-Impaired Individuals and Subjects With Normal Hepatic Function

Analgesic Allergy

United States
Yonsei University

Completed

A Crossover Trial of Chitosan Oligosaccharide on Post Prandial Glucose Control in Subjects With Normal, IFG and IGT

Impaired Glucose Tolerance | Impaired Fasting Glucose | Normal

Korea, Republic of
Hanlim Pharm. Co., Ltd.

Completed

Clinical Trial to Assess the Pharmacokinetic Characteristics of Lodivixx Tab. 5/160mg in Healthy Male Subjects (N=27)

Healthy Male Subjects
MegaPro Biomedical Co. Ltd.

Completed

Phase I , MTD, Pharmacokinetic, Safety/Tolerability, Efficacy of IOP Injection for MRI in Healthy Subjects

Magnetic Resonance Imaging

Taiwan
Syndax Pharmaceuticals

Completed

A Study to Examine the Effect of Omeprazole, Famotidine, and an Acidic Beverage on the Pharmacokinetics of Entinostat in Healthy Adult Subjects

Healthy Volunteers | Volunteers | Normal Volunteers | Human Volunteers

United States
University Hospital, Basel, Switzerland
Pharming Technologies B.V.; Clinical Trial Unit, University Hospital Basel,...

Completed

Recombinant Human C1 Esterase Inhibitor in the Prevention of Contrast-induced Nephropathy in High-risk Subjects (PROTECT)

Acute Kidney Injury

Switzerland
Sanofi Pasteur, a Sanofi Company

Completed

Study of a Candidate Clostridium Difficile Toxoid Vaccine in Healthy Adult Subjects Aged 40 to 75 Years in Japan

Clostridium Difficile Infection

Japan
Geropharm

Completed

Bioequivalence Study of Metformin 750 mg Tablets XR Versus Glucophage® Long 750 mg Tablets XR In Normal Healthy Subjects Under Fasting and Fed Conditions

Bioequivalence

Russian Federation

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