Search clinical trials for: Pharmacodynamics THC

Total 2530 results

Spanish Cooperative Group for the Treatment of...
AstraZeneca

Recruiting

Olaparib and Durvalumab (MEDI4736) in Patients With Metastatic Pancreatic Cancer and DNA Damage Repair Genes Alterations

Metastatic Pancreatic Cancer

Spain
St. Antonius Hospital
St. Antonius hospital Onderzoeksfonds; Ace pharmaceuticals; Allgen pharmaceuticals

Recruiting

Body Weight Adjusted Clopidogrel Treatment in Patients With CORonary Artery Disease (BW-ACCORD)

Coronary Artery Disease | Platelet Reactivity

Netherlands
University of California, San Francisco
National Institute on Drug Abuse (NIDA)

Recruiting

Pharmacokinetics and Pharmacodynamics of Nicotine With Use of Standardized Research Electronic Cigarette (SREC) (SREC22)

Nicotine Dependence | Cardiovascular Risk Factors | Tobacco Toxicity

United States
Geropharm

Recruiting

Double-blind, Randomized Comparative Cross-sectional Study of Pharmacodynamics and Pharmacokinetics of Drugs GP40141

Pharmacokinetics | Pharmacodynamics | Bioequivalence

Russian Federation
University of Oxford

Recruiting

A Phase 2 Trial Comparing Antiviral Treatments in Early Symptomatic Influenza (AD ASTRA)

Influenza | Influenza, Human

Thailand
Tel Aviv Medical Center

Recruiting

The Impact of THC on Pain Modulation in Fibromyalgia

Fibromyalgia, Primary

Israel
Alexion Pharmaceuticals, Inc.

Recruiting

Evaluation of Pharmacokinetics, Pharmacodynamics, Efficacy, Safety, and Immunogenicity of Ravulizumab Administered Intravenously in Pediatric Participants With Generalized Myasthenia Gravis (gMG)

Generalized Myasthenia Gravis | gMG

Spain, Italy, United States, France, Switzerland, Serbia, Japan, Netherlands
Yale University
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Multimodal Magnetoencephalography and Electroencephalography Exploration of the Acute Effects of THC Exposure on Neural Noise and Information Transmission Within Working Memory Networks (THC-MEG)

THC

United States
Fenix Innovation Group
Monash Health; Neurotech International

Not yet recruiting

Evaluating the Efficacy of NTI164 in Young People With Autism Spectrum Disorder

Autism Spectrum Disorder

Australia
Hoffmann-La Roche

Recruiting

A Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Anti-tumor Activity of RO7616789 in Advanced Small Cell Lung Cancer and Other Neuroendocrine Carcinomas

Small Cell Lung Cancer | Neuroendocrine Carcinoma

United States, Japan, Denmark, Spain, Poland
Aurigene Discovery Technologies Limited

Recruiting

A First in Human Study of AUR 103 Calcium to Evaluate Safety, Pharmacokinetics and Pharmacodynamics (BHARAT-1)

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Non Hodgkin Lymphoma | Solid Tumor, Adult

India
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Not yet recruiting

The Impact of Product Formulation on the Pharmacokinetics and Pharmacodynamics of Cannabis Edibles

Cannabis Use

United States
Eisai Co., Ltd.

Recruiting

A Study to Assess the Pharmacodynamics of Lemborexant in Korean Participants With Insomnia Disorder

Sleep Initiation and Maintenance Disorders

Korea, Republic of
BeiGene

Recruiting

Efficacy, Safety, and Pharmacodynamics of Tislelizumab Monotherapy and Multiple Tislelizumab-based Immunotherapy Combinations in Participants With Resectable Non-Small Cell Lung Cancer

Non Small Cell Lung Cancer

China
Kanyos Bio, Inc., a wholly-owned subsidiary of...
Pfizer

Recruiting

A Study of Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of KAN-101 in Celiac Disease (ACeD-it)

Celiac Disease

United States, Australia, New Zealand
Redx Pharma Plc
Simbec Research

Recruiting

Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of RXC007 in Idiopathic Pulmonary Fibrosis

Fibrosis | IPF

Italy, Spain, United States, Belgium, United Kingdom, Austria, Czechia, Poland, Switzerland
Hat Yai Medical Education Center

Recruiting

Role of Parasympathetic Activity in Mild to Severe Asthma With Fixed Airway Obstruction (PARASMA Study) (PARASMA)

Asthma | Airway Obstruction | Airway Remodeling | Parasympathetic Nervous System Diseases

Thailand
IGC Pharma LLC

Recruiting

IGC-AD1 Trial on Agitation in Dementia Due to Alzheimer's (IGC-AD1-P2)

Aggression | Depression | Anxiety | Alzheimer Disease | Memory Impairment | Agitated; State, Acute Reaction to Stress | Agitation,Psychomotor | Care Giving Burden | NPS | Aggressive Outburst

United States, Canada, Puerto Rico
CARE Pharma Shanghai Ltd.

Recruiting

A Study on the Safety, Tolerability, Efficacy, Pharmacokinetics and Pharmacodynamics of CAN106 in Subjects With PNH

Hemolysis | PNH

China
Arcus Biosciences, Inc.

Recruiting

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors (ARC-20)

Clear Cell Renal Cell Carcinoma | Solid Tumors

Korea, Republic of, United States
Kira Pharmacenticals (US), LLC.

Not yet recruiting

Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of KP104 to Treat Glomerulonephritis

Glomerulonephritis
Fujian Shengdi Pharmaceutical Co., Ltd.

Recruiting

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Subcutaneous Injections of HRS9531 in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

China
University of California, San Diego

Recruiting

Effects of Cannabidiol and Tetrahydrocannabinol on Microbiome and Neuroinflammation in HIV (CAMI)

HIV | Cannabis | Microbiome | THC | Neuroinflammatory Response | Neuroinflammatory Disease

United States
Kira Pharmacenticals (US), LLC.

Not yet recruiting

Study to Evaluate Safety, Tolerability and Pharmacodynamics of KP104 in Participants With Thrombotic Microangiopathy Secondary to Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Hoffmann-La Roche
Chugai Pharmaceutical Co.

Recruiting

A Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamics Of Satralizumab In Patients With Anti-N-Methyl-D-Aspartic Acid Receptor (NMDAR) Or Anti-Leucine-Rich Glioma-Inactivated 1 (LGI1) Encephalitis (Cielo)

NMDAR Autoimmune Encephalitis | LGI1 Autoimmune Encephalitis

United States, Korea, Republic of, China, Japan, Czechia, Italy, Poland, Austria, Brazil, Argentina, Netherlands, Taiwan, Denmark, France, Ghana
University of Chicago
Lucile Packard Children's Hospital

Not yet recruiting

Oxytocin Pharmacokinetics and Pharmacodynamics

Blood Loss | Cesarean Section Complications | Post Partum Hemorrhage

United States
Maisa N. Feghali, MD

Recruiting

Exenatide Pharmacokinetics and Pharmacodynamics in Gestational Diabetes

Gestational Diabetes

United States
Kira Pharmacenticals (US), LLC.

Not yet recruiting

To Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of KP104

Paroxysmal Nocturnal Hemoglobinuria

China
L. Nicolas Gonzalez Castro, MD, PhD
Merck Sharp & Dohme LLC

Recruiting

Surgical Pembro +/- Olaparib w TMZ for rGBM

Glioblastoma | Recurrent Glioblastoma

United States
Pacira Pharmaceuticals, Inc

Recruiting

Phase 1, Dose Escalation Study to Evaluate of Safety, Pharmacokinetics and Pharmacodynamics of Liposomal Bupivacaine 13.3 Administered Via a Single Intrathecal Injection to Healthy Volunteers

Healthy

United States
UNICANCER

Recruiting

TARGETed Therapy Drug MONITOring in DIGestive Oncology (TARGETMONITO)

Metastatic Colorectal Cancer | Hepatocellular Carcinoma | Neuroendocrine Tumors | GIST | Digestive Cancer

France
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Behavioral Pharmacology of THC and Beta-Myrcene

Cannabis Use

United States
argenx

Recruiting

A Clinical Trial to Investigate the Long-term Safety and Tolerability, Efficacy, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of ARGX-117 in Adults With Multifocal Motor Neuropathy (ARDA+)

Multifocal Motor Neuropathy (MMN)

United Kingdom, Spain, United States, Italy, Netherlands, Germany, France, Belgium, Canada, Poland, Austria
Brown University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Recruiting

Cannabis' Impact on Alcohol Consumption

Alcohol Drinking | Cannabis | Alcohol Use Disorder | Cannabis Use

United States
Zhejiang Doer Biologics Co., Ltd.

Recruiting

A First in Human (FIH) Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DR10624

Healthy, Obesity, Metabolically

New Zealand
Sunshine Lake Pharma Co., Ltd.

Recruiting

A Study of the Pharmacokinetics, Pharmacodynamics, and Safety of Rongliflozin in Type 2 Diabetic Subjects With Renal Impairment

Type 2 Diabetes

China
Geron Corporation

Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of Imetelstat in Combination With Ruxolitinib in Participants With Myelofibrosis

Myelofibrosis

United States
Centre Hospitalier Intercommunal Creteil

Recruiting

Pharmacokinetics-pharmacodynamics of Morphine With or Without Midazolam Administered by Continuous Infusion in Neonatal Intensive Care

Sedation Complication | Mechanical Ventilation in Neonates

France
University Health Network, Toronto

Recruiting

Improving Pain Disability With the Use of Oral Cannabinoids

Chronic Pain | Cannabis | Opioid Use

Canada
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

A Phase I Single- and Multiple- Ascending Dose and Food Effect Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS-7535 in Healthy Subjects

Healthy Subjects
Beijing Suncadia Pharmaceuticals Co., Ltd

Not yet recruiting

Single Ascending Dose and Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SHR-1816 in Healthy Subjects

Diabetes
Johns Hopkins University
Canopy Growth Corporation

Recruiting

Pharmacokinetics and Pharmacodynamics of CHI-914 in Healthy Participants

Behavioral Pharmacology of Cannabis

United States
University of California, San Diego
Center for Medicinal Cannabis Research

Not yet recruiting

THC Effects on Glucose in Type 2 Diabetes

Type 2 Diabetes

United States
United BioPharma

Recruiting

A Study to Evaluate the Pharmacodynamics, Pharmacokinetics, Safety, and Efficacy of UB-221 IV Infusion as an add-on Therapy in Patients With Chronic Spontaneous Urticaria

Chronic Spontaneous Urticaria

Taiwan
Johns Hopkins University
Substance Abuse and Mental Health Services Administration (SAMHSA)

Recruiting

Comparative Pharmacokinetic and Pharmacodynamic Effects of Delta-8 and Delta-9 THC

Behavioral Pharmacology of Cannabis

United States
Gannex Pharma Co., Ltd.
Ascletis Pharmaceuticals Co., Ltd.

Recruiting

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASC61in Subjects With Advanced Solid Tumors

Advanced Solid Tumors

United States
FG Brasil LTDA
3F Clinical Trials LTDA

Not yet recruiting

CBD (Cannabidiol)/THC (Tetrahydrocannabinol) Solution as a Pharmacological Strategy for Patients With Fibromyalgia (FibroCann)

Fibromyalgia
University Hospital, Ghent
University Ghent; Kom Op Tegen Kanker

Recruiting

Intraperitoneal Aerosolized Nanoliposomal Irinotecan (Nal-IRI) in Peritoneal Carcinomatosis From Gastrointestinal Cancer (PIPAC-NAL-IRI)

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Small Bowel Cancer | Bile Duct Cancer | Peritoneal Carcinomatosis | Peritoneal Metastases | Appendix Cancer

Belgium
ViGenCell Inc.

Not yet recruiting

A Prospective, Open Label, Dose-escalation, SAD/MAD, Multicenter, 24weeks, Phase I/IIa Clinical Trial to Evaluate the Safety, Tolerability and Pharmacodynamics of Investigational Product (VM-001) in Patients With Graft-versus-host Disease(GvHD)

Graft Versus Host Disease
ISBRG Corp
National Advanced Driving Simulator

Recruiting

Detection of Cannabis Impairment With ISBRG's SpotLight-THC

Cannabis

United States

Search clinical trials for: Pharmacodynamics THC

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