Search clinical trials for: Potassium Sparring Diuretic

Total 3042 results

Cambridge University Hospitals NHS Foundation Trust
Medical Research Council

Recruiting

Comparison of Optimal Hypertension Regimens (AIMHY-INFORM)

Hypertension

United Kingdom
Navitas Pharma
IndiPharm Inc.

Not yet recruiting

Cicletanine in Hypertension With Diabetes: Added Magnesium Preserves Potassium and Sodium (CHAMP)

Diabetes | Hyponatremia | Arterial Hypertension | Hypokalemia
University Hospital Goettingen
Society for Pediatric Nephrology (Germany); Deutsche Gesellschaft für Nephrologie and other collaborators

Recruiting

European Alport Therapy Registry - European Initiative Towards Delaying Renal Failure in Alport Syndrome

Pediatric Kidney Disease | Alport Syndrome | Hereditary Kidney Disease | Thin Basement Membrane Disease | Familial Benign Hematuria

Germany
National Institutes of Health Clinical Center (CC)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University... and other collaborators

Recruiting

Spironolactone for Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

United States
University of Virginia

Recruiting

Effect of Spironolactone on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess

Obesity | Polycystic Ovary Syndrome | Hyperandrogenemia

United States
Wroclaw Medical University

Completed

Sodium Chloride vs. Glucose Solute as a Volume Replacement Therapy During Decongestion in Acute Heart Failure (SOLVRED-AHF)

Heart Failure | Acute Heart Failure | Congestion

Poland
University of Texas Southwestern Medical Center
scPharmaceuticals, Inc.

Active, not recruiting

Furoscix in Heart Failure Patients With Diuretic Resistance (RESISTANCE-HF)

Heart Failure

United States
Organon and Co

Terminated

A Study of Losartan Compared to Losartan/HCTZ in Pediatric Patients With Hypertension (0954A-327)

Hypertension
University of Missouri-Columbia

Active, not recruiting

ENAC Blockade and Arterial Stiffness

Insulin Resistance | Overweight and Obesity

United States
Indiana University
Wayne State University; Vanderbilt University; Case Western Reserve University; Inova Fairfax Hospital

Completed

B-lines Lung Ultrasound Guided ED Management of Acute Heart Failure Pilot Trial (BLUSHED-AHF)

Heart Failure | Acute Cardiac Failure | Acute Cardiac Pulmonary Edema | Heart Failure Acute

United States
Connecticut Children's Medical Center

Completed

Furosemide Use to Fill the Bladder of Pediatric Females Awaiting Pelvic Ultrasound

Ovarian Torsion

United States
Guangdong Women and Children Hospital

Completed

Efficacy and Safety of Dingkundan Combined With Combination Oral Contraceptives in the Treatment of PCOS

PCOS

China
Organon and Co

Completed

LAAS (Losartan Anti-Atherosclerosis Study)(0954-330)(COMPLETED)

Hypertension
Rambam Health Care Campus

Completed

The Heart Failure Diuresis Efficacy Comparison (DEA-HF) Study (DEA-HF)

Chronic Heart Failure | Congestive Heart Failure | Diuretics Drug Reactions

Israel
Population Health Research Institute
Canadian Institutes of Health Research (CIHR); Boston Scientific Corporation

Active, not recruiting

Colchicine and Spironolactone in Patients With MI / SYNERGY Stent Registry (CLEAR SYNERGY)

ST Elevation Myocardial Infarction | Non ST Elevation Myocardial Infarction

Canada
Organon and Co

Completed

BP-EASE -Effectiveness of Losartan 50 mg/Hydrochlorothiazide (HCTZ) 12.5 mg Versus Valsartan 80 mg/HCTZ 12.5 mg Titrated as Needed in Patients With Essential Hypertension Not Controlled on Monotherapy (0954A-333) (EASE)

Hypertension
Ospedale San Raffaele

Completed

Natriuretic Effect of Amiloride in Relation to the Alpha Adducin Gene (ADD-AMI) RS4961 Variant (ADD-AMI)

Genetic Hypertension | Hypertension Essential | Salt Excess

Italy
Organon and Co

Completed

SAALT: Subtracting Salt and Adding Losartan Trial (0954A-335)

Hypertension
Organon and Co

Completed

A 52 Week Study to Evaluate the Effects of Losartan With or Without HCTZ on Plasma Glucose, Metabolic Parameters, Blood Pressure in Hypertensive Patients With Metabolic Syndrome (0954A-331)

Hypertension | Metabolic Disorder
Ospedale San Raffaele

Completed

Pharmacogenetics of Torasemide and Spironolactone in Hypertension Treatment (ALTUM)

Hypertension | Drug Effect | Genetic Predisposition

Italy
Imperial College London
Institute of Neuroscience and Medicine, Julich, Germany

Withdrawn

Investigating Salt Taste Threshold in Patients Being Investigated for Primary Hyperaldosteronism Before and After Treatment. (AldoSalt)

Hypertension | Hyperaldosteronism; Primary | Salt; Excess | Appetite Disorders

United Kingdom
Rush University Medical Center

Terminated

Comparison of Diuretic Effect With Furosemide Alone Versus the Combination of Furosemide and Albumin in Cirrhotic Patients

Fluid Overload | Cirrhosis, Liver | Volume Overload

United States
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Delivering a Diuretic Into the Liver Artery Followed by Plugging up the Artery to Starve Out Liver Cancer Cells

Unresectable Hepatocellular Carcinoma

United States
Sarfez Pharmaceuticals, Inc.

Completed

Comparison of Once Daily 40 mg Torsemide With Twice-daily 40 mg Furosemide

Body Weight Changes

India
AstraZeneca

Active, not recruiting

Study to Assess Efficacy and Safety of SZC for the Management of High Potassium in Patients With Symptomatic HFrEF Receiving Spironolactone (REALIZE-K)

Heart Failure With Reduced Ejection Fraction | Hyperkalaemia

United States, Spain, Canada, Brazil, Hungary, Czechia, Ukraine, Poland, United Kingdom
Melanie Maykin, MD

Completed

Furosemide vs. Placebo for Severe Antepartum Hypertension

Pregnancy Complications | Pre-Eclampsia | Hypertension, Pregnancy-Induced | Hypertension in Pregnancy

United States
Seoul National University Hospital

Completed

A Study to Investigate the Effect of Urine Acid-base Disequilibrium on the Pharmacokinetics of Captopril

Hypertension

Korea, Republic of
KBP Biosciences

Completed

Safety, Tolerability and Pharmacokinetics of KBP-5074 in Healthy Subjects and Subjects With Renal Impairment

Healthy | Renal Insufficiency

United States
M.D. Anderson Cancer Center

Active, not recruiting

Phase I, Open-Label, Study of Tumor Infiltrating Lymphocytes Engineered With Membrane Bound IL15 Plus Acetazolamide in Adult Patients With Metastatic Melanoma

Melanoma | Metastatic Melanoma | Tumor

United States
University of Palermo
University of Roma La Sapienza

Completed

The Use of Drospirenone/Estetrol in Random Start Rapid Endometrial Preparation

Endometrial Polyp | Endometrial Diseases

Italy
University of Palermo
University of Roma La Sapienza

Completed

The Use of Drospirenone/Estetrol, Nomegestrol Acetate/Estradiol and Ethinylestradiol/Dienogest in Random Start Rapid Endometrial Preparation

Endometrial Polyp | Endometrial Diseases

Italy
University of Texas Southwestern Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Treatment for Calcium Phosphate Kidney Stone Disease

Calcium Phosphate Kidney Stones

United States
TenNor Therapeutics (Suzhou) Limited

Completed

Efficacy and Safety of Rifasutenizol (TNP 2198) in Participants With H. Pylori Infection

H.Pylori Infection

China
Pfizer

Completed

A Study to Learn How the Body Processes Spironolactone and Hydrochlorothiazide Film Coated Tablets Manufactured at Two Sites: Viatris and Neolpharma

Healthy Participants

United States
Shandong University
Zibo Central Hospital; Peking University Care Luzhong Hospital; Yuncheng Traditional... and other collaborators

Completed

Bismuth-containing Quadruple Therapy for Helicobacter Pylori First-line Treatment of Different Tetracycline Doses

Helicobacter Pylori Infection

China
Mayo Clinic

Enrolling by invitation

A Study of Ultra High Dose Diuretics to Treat Heart Failure

Heart Failure; With Decompensation

United States
Emory University
National Cancer Institute (NCI); Blue Earth Diagnostics

Active, not recruiting

Comparison of 18F-rhPSMA-7.3 PET/CT With and Without Furosemide in Biochemical Recurrence of Prostate Cancer

Prostate Adenocarcinoma | Recurrent Prostate Carcinoma

United States
Eli Lilly and Company

Active, not recruiting

A Study of LY3437943 in Postmenopausal Female Participants Who Are Overweight or Obese

Overweight

United States
Advicenne Pharma

Terminated

Study Evaluating Subjects With Distal Renal Tubular Acidosis

Distal Renal Tubular Acidosis

United States, Canada
KBP Biosciences

Completed

Safety, Tolerability, and Pharmacokinetics of KBP-5074 Following Oral Administration in Chronic Kidney Disease

Chronic Kidney Disease

United States
Advicenne Pharma

Withdrawn

Study Evaluating Patients With Cystinuria

Cystinuria

France, Belgium
University of Alberta

Suspended

Diuretic Use in Hemodialysis Patients With Residual Renal Function (DIURESED)

End Stage Renal Disease on Dialysis

Canada
Alexandria University

Completed

Gender-based Differences in the Outcome of Treatment With Aldosterone Antagonists in Patients With Heart Failure (GBDAL-HF)

Heart Failure | Heart Failure NYHA Class II | Heart Failure NYHA Class III | Heart Failure With Reduced Ejection Fraction | Heart Failure NYHA Class IV

Egypt
KBP Biosciences
Medpace, Inc.

Completed

Bioavailability of KBP-5074 Tablet vs Capsule Formulations

Bioequivalence

United States
Istituto Auxologico Italiano
European Society of Hypertension; Chinese Hypertension League

Completed

Optimal Blood Pressure and Cholesterol Targets for Preventing Recurrent Stroke in Hypertensives (ESH-CHL-SHOT)

Stroke | Hypertension | Transient Ischemic Attack

Russian Federation
Johannes Grand

Completed

Acute Effects of Furosemide on Hemodynamics and Pulmonary Congestion in Acute Decompensated Heart Failure.

Acute Heart Failure

Denmark
Brigham and Women's Hospital

Completed

MR Antagonist and STRIATIN

Hypertension | Genetics Hypertension

United States
Pfizer

Completed

Voxelotor CYP and Transporter Cocktail Interaction Study

Sickle Cell Disease

United States
Bristol-Myers Squibb

Completed

A Study to Investigate the Effects of BMS-986278 on Drospirenone and Ethinyl Estradiol Drug Levels in Healthy Female Participants

Healthy Volunteers

Canada
University of New Mexico
Dialysis Clinic, Inc.

Terminated

Diuretic/Cool Dialysate Trial (DIDIT)

Chronic Kidney Insufficiency

United States

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