Search clinical trials for: Sigma-1 Receptor Agonist

Total 65855 results

Foldax, Inc

Active, not recruiting

Clinical Investigation for the Foldax Tria Mitral Valve- India

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Disease | Mitral Stenosis

India
Imperial College London
Pelican Cancer Foundation

Recruiting

Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers (IMPRESS)

Cancer | Colorectal Neoplasms | Magnetic Resonance Imaging | General Surgery | Colon, Sigmoid

United Kingdom
Galderma R&D
Chiltern International Inc.

Completed

Mirvaso® Utilisation and Patient Satisfaction Evaluation (MUSE) (MUSE)

Rosacea

Canada
Tohoku University

Completed

Vitamin D Supplementation Prevents Elderly Pneumonia

Bacterial Pneumonia

Japan
Lu Hua

Not yet recruiting

Effect of Bupivacaine Liposome Anterior Serratus Deep Block on Chronic Pain After Breast Cancer Surgery: a Randomized Controlled Study

Breast Cancer Patients With Chronic Pain After Surgery

China
Cukurova University

Not yet recruiting

Effect of Mobile Application Usage on Drug Compliance After Thyroidectomy

Patient Acceptance of Health Care | Drug Compliance
Pere Planellas Giné

Completed

Complete Mesocolon Excision vs Locoregional Lymphadenectomy in Sigmoid Colon Cancer (CMELL) (CMELL)

Colorectal Cancer | Sigmoid Cancer

Spain
National Institute of Nursing Research (NINR)

Not yet recruiting

A Natural History Study of RYR1-Related Disorders

Ryanodine Receptor 1-Related Myopathy | Ryanodine Receptor 1 Related Disorders

United States
Sigma-Tau Research, Inc.
Colorado Prevention Center

Completed

Safety and Efficacy of Propionyl-L-Carnitine in the Treatment of Peripheral Arterial Disease (Intermittent Claudication)

Peripheral Vascular Diseases | Intermittent Claudication

United States
RegeneRx Biopharmaceuticals, Inc.
sigma-tau i.f.r. S.p.A.

Completed

Study of Thymosin Beta 4 in Patients With Venous Stasis Ulcers (SSVS)

Venous Stasis Ulcers

Italy, Poland
CONRAD
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Coital Pharmacokinetics/Pharmacodynamics (PK/PD) of Tenofovir Gel

Pharmacokinetics of 1% Tenofovir Gel Following Coitus | Pharmacodynamics of 1% Tenofovir Gel Following Coitus

United States
Merck Sharp & Dohme LLC

Recruiting

Sacituzumab Tirumotecan (MK-2870) as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors (MK-2870-008)

Non-small Cell Lung Cancer | Solid Tumors | Programmed Cell Death-1 (PD1, PD-1) | Programmed Cell Death 1 Ligand 1(PDL1, PD-L1) | Programmed Cell Death 1 Ligand 2 (PDL2, PD-L2)

Japan
Sorrento Therapeutics, Inc.
Kimberly-Clark Corporation

Completed

Sofusa System With Sumatriptan (KC5010) Phase 1 Dose Escalation Safety and PK Study (KCC-SMT-002) (KCC-SMT-002)

Migraine Disorders

United States
Ningbo No. 1 Hospital

Recruiting

Conventional Clipping Versus Punching Closure

the Rate of Complete Closure

China
Ningbo No. 1 Hospital

Recruiting

Effectiveness of Mannitol Versus Polyethylene Glycol Electrolyte Dispersion as a Salve for Patients With Inadequate Bowel Preparation: a Randomized Controlled Clinical Trial

Bowel Cleansing; Good Taste

China
Ningbo No. 1 Hospital

Not yet recruiting

Effects of Febuxostat for Lowering Uric Acid in NAFLD Patients With Gout

Nonalcoholic Fatty Liver Disease

China
Ningbo No. 1 Hospital

Completed

Pulsed Field Ablation for Paroxysmal Supraventricular Tachycardia（PSVT）

Paroxysmal Supraventricular Tachycardia

China
Ningbo No. 1 Hospital

Unknown

Prepackaged Nutritional Formulations Versus Restricted Diet for Bowel Preparation

Bowel Preparation

China
Ningbo No. 1 Hospital

Completed

MAFLD-simplified Definition as an Optimized Risk Stratification Tool for Predicting Metabolic Outcomes

Metabolic Associated Fatty Liver Disease
Ningbo No. 1 Hospital

Completed

A Comparison of Bowel Preparation for Colonoscopy Between Digestive Physicians and Non-digestive Physicians

Bowel Preparation

China
University of Yaounde 1

Unknown

The Comparative Efficacy and Safety of Two General Anesthesia Protocols Consisting of Fentanyl Plus Propofol Plus Rococuronium Plus Isoflurane Versus Ketamime Plus Magnesium Sulphate Plus Lidocaine Plus Clonidine Plus Propofol Plus Rococuronium Plus Isoflurane for Gynaecology Surgery in Cameroon (OFA-AFRO)

Surgery | Anesthesia | Clinical Trial | Gynecology | Opioids

Cameroon
Ningbo No. 1 Hospital

Unknown

Reasons for Nonattendance Inpatient Colonoscopy

Inpatient | Colonoscopy Nonattendance

China
University of Oran 1

Completed

Surgical Practices in Algeria : the Cholecystectomy

General Surgery | Cholecystectomy | Practice Guidelines as Topic
Ningbo No. 1 Hospital

Unknown

Effectiveness of Enteral Nutrition for Dose Reduction of Low Dose PEG

Bowel Preparation

China
Ningbo No. 1 Hospital

Completed

Second Forward View Examination of Proximal Colon on Adenoma Detection Rate

Colon Adenoma

China
Ningbo No. 1 Hospital

Completed

Alcohol Consumption and Type 2 Diabetes Mellitus Risk in Nonalcoholic Fatty Liver Disease

Nonalcoholic Fatty Liver Disease | Type2 Diabetes Mellitus | Light-to-moderate Alcohol Consumption

China
Ningbo No. 1 Hospital

Completed

The Impact of Experienced Endoscopy Nurse Participation on Polyp and Adenoma Detection During Colonoscopy

Adenoma | Polyp

China
Team Type 1, Inc.

Unknown

Glycemic Response to Road Cycling in Type 1 Diabetes

Type 1 Diabetes
Sun Yat-sen University

Not yet recruiting

A Prospective, Randomized, Open, Parallel-controlled, Superior-efficacy Clinical Study of Radical Sigmoidectomy for Sigmoid Cancer Versus Radical Sigmoidectomy Combined With Indocyanine Green Fluorescence Imaging Lymphatic Tracing Dissection in the Treatment of Sigmoid Cancer

Sigmoid Cancer
Sumitomo Pharma Co., Ltd.

Completed

DSP-3025 A Phase 1 Study of Healthy Male Volunteers

Healthy

Japan
Nanfang Hospital of Southern Medical University

Unknown

Indocanine Green as Tracer for Lymph Nodes Dissection in Station 253

Rectal Carcinoma | Sigmoid Colon Carcinoma

China
Klinik Hirslanden, Zurich

Completed

Comparison Two Point of Care Coagulation Monitoring Systems - the ROTEM Sigma and the Quantra Devic

Non Inferiority of the Quantra Device

Switzerland
Fundacion para la Investigacion Biomedica del Hospital...
Pfizer

Completed

Effect Of A CCR5 Coreceptor Antagonist On The Latency And Reservoir Of HIV-1

HIV-1

Spain
ViiV Healthcare
Pfizer

Completed

Trial of Maraviroc (UK-427,857) in Combination With Zidovudine/Lamivudine Versus Efavirenz in Combination With Zidovudine/Lamivudine (MERIT)

HIV-1

United States, Canada, United Kingdom, Netherlands, Argentina, Australia, Belgium, South Africa, Switzerland, Italy, Puerto Rico, Brazil, Mexico, Poland
Sigma-Tau Research, Inc.
Rhode Island Hospital

Completed

This is an Early Study to Investigate the Effect of Gimatecan® in Adults With Malignant Glioma.

Malignant Glioma

United States
sigma-tau i.f.r. S.p.A.
MDS Pharma Services

Completed

A Phase II Trial to Assess Hemodynamic Effects of Istaroxime in Pts With Worsening HF and Reduced LV Systolic Function (HORIZON-HF)

Heart Failure
Rambam Health Care Campus
Israel Science Foundation

Completed

Israeli Multi Ethnic Centenarian Project (IMECP)

LONGEVITY 1

Israel
Japan Clinical Oncology Group
Ministry of Health, Labour and Welfare, Japan

Completed

OVCA-NAC-P2: Study of Chemotherapy Followed by Cytoreductive Surgery for Ovarian, Tubal and Peritoneal Cancers: JCOG0206

Ovarian Neoplasms | Fallopian Tube Neoplasms | Peritoneal Neoplasms

Japan
Shimousa Hematology Study Group
Epidemiological and Clinical Research Information Network

Unknown

Discontinuation of Dasatinib in Patients With Chronic Myeloid Leukemia-CP Who Have Maintained Complete Molecular Remission for Two Years; Dasatinib Stop Trial

Chronic Myeloid Leukemia

Japan
Taiho Pharmaceutical Co., Ltd.

Completed

Adjuvant Chemotherapy Trial of TS-1 for Gastric Cancer (ACTS-GC)

Gastric Cancer

Japan
Japan Clinical Oncology Group
Ministry of Health, Labour and Welfare, Japan

Terminated

Randomized Controlled Trial to Evaluate Surgical Approaches to Gastric Cancer Invading the Esophagus (JCOG9502)

Gastric Neoplasm

Japan
St. Mary's University, Twickenham

Recruiting

Caffeine, DNA and Cognition

Cognitive Function 1, Social

United Kingdom
GI Biome, Inc.

Recruiting

Live Biotherapeutic Product GB104 Phase 1 Study in Colorectal Cancer

Cancer | Colorectal Cancer | Rectal Cancer | Solid Tumor | Sigmoid Colon Cancer | Rectosigmoid Junction Cancer

Korea, Republic of
Axsome Therapeutics, Inc.

Completed

A Trial of AXS-05 in Patients With Major Depressive Disorder (GEMINI)

Depression | Major Depressive Disorder

United States
Herlev Hospital

Completed

Confocal Laser Endomicroscopy Findings in Patients With Proctosigmoiditis Before and After Initiation of Treatment

Colitis, Ulcerative

Denmark
Pathalys Pharma
Launch Therapeutics

Recruiting

Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-1 (PATH-1)

Secondary Hyperparathyroidism | End-stage Kidney Disease (ESKD)

United States, Bulgaria, Spain, Portugal, Poland, Serbia
Haruhiko Fukuda
Ministry of Health, Labour and Welfare, Japan

Completed

Trial to Evaluate Radiotherapy Followed by Endocrine Therapy Vs Endocrine Therapy Alone for PSA Failure After Radical Prostatectomy

Prostate Cancer

Japan
Eastern Mediterranean University

Not yet recruiting

The Effect of Laughter Yoga on Self-Care, Quality of Life and Stress Level in Menopause

Stress | Menopause | Laughter | Self

Cyprus
ViiV Healthcare
Pfizer

Terminated

Comparative Trial Of Maraviroc Versus Emtricitabine/Tenofovir Both With Darunavir/Ritonavir In Antiretroviral-Naive Patients Infected With CCR5 Tropic HIV 1 (MODERN)

HIV-1

United States, Netherlands, Spain, Puerto Rico, Canada, Australia, Germany, Sweden, Poland, Portugal, Switzerland, France, Denmark, Italy, Belgium, United Kingdom, Hungary, Austria, Finland
Eastern Mediterranean University

Not yet recruiting

Acupressure Therapy Method and Heel Blood Effect of Position on Pain and Physiological Parameters

Newborn; Vitality

Cyprus

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