Search clinical trials for: Single Gene Polymorphism

Total 274939 results

Max-Planck-Institute of Psychiatry

Recruiting

Deep Phenotyping for Clinical Inferring Response in Treatment Resistant Depression (DECIDE)

Depressive; Disorder, Major, Single Episode, Major, With Psychotic Symptoms | Depressive; Disorder, Major, Single Episode, Major (Without Psychotic Symptoms) | Depressive Disorder, Major, Recurrent, With Psychotic Symptoms | Depressive Disorder, Major, Recurrent, Without Psychotic Symptoms and other conditions

Germany
Dongyang People's Hospital

Not yet recruiting

Base Curves of Bandage Contact Lenses and Their Effects on Post Trans-PRK Vision and Pain

Myopia

China
Peking University First Hospital

Recruiting

Establishment of a Multidimensional Prediction Model for the Natural Course of VHL Disease-related Renal Cell Carcinoma

Renal Cell Carcinoma | VHL Syndrome

China
The Affiliated Hospital Of Guizhou Medical University

Not yet recruiting

Population Pharmacokinetic Study of the Effect of Polymorphisms in the ABCB1 and CES1 Genes on the Pharmacokinetics of Dabigatran

Combined Analysis of Polymorphisms and Dabigatran Pharmacokinetic Parameters
Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Elderly/Unfit Ph- B-ALL

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Changchun GeneScience Pharmaceutical Co., Ltd.

Recruiting

A Phase I Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Oral Dose Escalation of GS1-144 Tablets and the Effects of Food on the Pharmacokinetics of GS1-144 in a Chinese Population

Healthy Volunteer | Vasomotor System; Labile

China
University of Campania "Luigi Vanvitelli"
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico; University of Milan and other collaborators

Recruiting

The PRO-FUTURE Project (PRO-FUTURE)

Chronic Kidney Diseases | Ureteropelvic Junction Obstruction

Italy
AstraZeneca
Parexel

Recruiting

A Study to Investigate Safety, Tolerability, and Pharmacokinetics of Oral AZD0233 Compared With Placebo in Healthy Adult Participants.

Dilated Cardiomyopathy

United States
Guangzhou Medical University
Ningbo SensCure Biotechnology Co., Ltd.

Recruiting

Single-center Clinical Study on the Safety and Effect of Bronchoscopic Cryotherapy in Patients With Chronic Cough (ColdCough)

Chronic Cough

China
Austin Institute for Clinical Research
SkinCeuticals

Recruiting

Single-Blind Study Assessing the Use of a Topical Antioxidant With A Series of Laser Procedures to Reduce Sebum Production

Acne

United States
University Hospital, Brest

Not yet recruiting

Residual Pulmonary Vascular Obstruction Index Computed With Ventilation/Perfusion SPECT/CT Imaging to Predict the Risk of Venous Thromboembolism Recurrence in Patients With Pulmonary Embolism (PRONOSPECT) (PRONOSPECT)

Venous Thromboembolism | Pulmonary Embolism

France
Massachusetts General Hospital
n-Lorem Foundation

Not yet recruiting

Single Participant Study of an Experimental ASO Treatment for TUBB4A-related Leukodystrophy

Genetic Disease
Soonchunhyang University Hospital

Not yet recruiting

Digital Single-operator Cholangioscopy and Intraductal Ultrasound for Nonicteric Biliary Strictures (Spy+IDUS)

Cholangiocarcinoma | Biliary Stricture
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

Pharmacology of Mupirocin in Nasal Application in Healthy Volunteers: Monocentric Study (MUPIPHARM)

Healthy | Staphylococcus Aureus Infection

France
Research Institute for Physical Chemical Problems...
Unitary Enterprise UNITEHPROM BSU; City Clinical Hospital of Emergency Medical...

Not yet recruiting

Clinical Study of the Effectiveness, Tolerability and Safety of the Drug "Anti-spike, Gel, 100 g in Bottles in Package No. 1" Produced by the Republican Unitary Enterprise "Unitekhprom BSU", With a Single Intraperitoneal Use After Surgery in Adult Patients With Acute Phlegmonous Appendicitis (OLTOSPAN-02)

Abdominal Adhesions

Belarus
University Health Network, Toronto

Not yet recruiting

Ultra-high Dose Radiation for Liver Metastasis Using MR-guided TReatment With Stereotactic Ablative Single-fraction (ULTRAS)

Liver Metastases
Sonoma Biotherapeutics, Inc.

Recruiting

Study of Single Doses of SBT777101 in Subjects With Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States
Vastra Gotaland Region
Region Östergötland; Region Skane; Dalarna County Council, Sweden; Region Örebro... and other collaborators

Not yet recruiting

Single- vs Two-staged Excisions of Thin Melanoma (WvW)

Melanoma | Surgery
The First Affiliated Hospital, Guangzhou University...

Not yet recruiting

A Single-arm Pilot Study of Tislelizumab Combined With Anlotinib in Patients With Advanced NSCLC With Driver-negative After Progression to Immunotherapy

Advanced NSCLC
Centre Hospitalier Universitaire de Nīmes

Recruiting

NETTI Wheelchair: Does Dynamic Mode or Static Mode Affect the Sitting Position in Patients With Involuntary Movements ? (DYNAMIC SYSTEM)

Involuntary Movements | Hyperextension Spasms

France
Queen's University

Recruiting

Evaluating Changes in Skeletal Muscle Proteins Following Resistance Exercise and Single-Leg Disuse

Healthy | Skeletal Muscle Atrophy | Skeletal Muscle Hypertrophy

Canada
Beijing Friendship Hospital

Recruiting

Effectiveness and Safety of Single-session Endoscopic Stone Extraction

Choledocholithiasis With Acute Cholangitis

China
Equilibra Bioscience LLC

Recruiting

A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B)

Hemophilia A | Hemophilia B | Healthy Participants

United States
Sichuan University

Recruiting

Effects of Aromatherapy on Anxiety and Pain During Dental Treatment in Adults

Dental Anxiety

China
West China Hospital

Recruiting

Safety and Efficacy of a Single Subretinal Injection of JWK002 Gene Therapy in Subjects With X-linked Retinoschisis(XLRS)

X Linked Retinoschisis

China
S-Alpha Therapeutics, Inc.

Recruiting

Pivotal Study of SAT-001 in Treatment of Pediatric Patient With Myopia

Myopia

Korea, Republic of
BeiGene

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single- and Multiple-Ascending Doses and Food Effect of BGB-45035

Autoimmune Diseases | Healthy Volunteers | Healthy Subjects | Healthy Participants | Healthy Adult Participants

Australia
Sahajanand Medical Technologies Limited
Qmed Consulting A/S

Recruiting

Hydra Single-centre Experience - Copenhagen, Denmark

Aortic Valve Stenosis

Denmark
Thammasat University Hospital

Recruiting

Comparing Single Dose and Multiple Dose of Dexamethasone Post TKA

Pain, Postoperative | Osteo Arthritis Knee

Thailand
Helwan University

Not yet recruiting

Palbociclib in Metastatic Breast Cancer: Gene Polymorphism-based Study in Egyptian Patients. (Palbociclib)

Metastatic Breast Cancer | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Hormone-receptor-positive Breast Cancer
Mahidol University

Not yet recruiting

The Efficacy of Pedometer-motivated Physical Activity for the Management of Patients With MASLD.

BMI | Metabolic Syndrome | Insulin Resistance | NAFLD | Genetic Polymorphism | Cardiovascular Disease (CVD) | MASLD | Daily Step Count
Craig Erickson
Healx Limited

Recruiting

Placebo-Controlled, Single-Dose Challenge Study of Gaboxadol in Adult Males With Fragile X Syndrome (FXS)

Fragile X Syndrome

United States
Augusto Vaglio

Recruiting

GWAS and EWAS in Patients With Erdheim-Chester Disease

Erdheim-Chester Disease

France, Italy, Spain
Universitair Ziekenhuis Brussel

Recruiting

Multicenter Registry of Atrial Fibrillation Ablation With Radiofrequency Balloon Catheter (COLLABORATE)

Atrial Fibrillation

Belgium
Guangzhou Institute of Respiratory Disease

Recruiting

A Single-arm Pilot Study of First-line Treatment With Carbognilumab Combined With Chemotherapy in Patients With STK11-mutated Advanced or Postoperative Recurrent Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

China
Istituto Clinico Humanitas

Not yet recruiting

Outcomes of Transanal Tran-section and Single-stapled (TTSS) Ileal Pouch-Anal Anastomosis (TTSS-Pouch)

Ulcerative Colitis

Italy
Beijing Friendship Hospital

Recruiting

Efficacy and Safety of Single-session Endoscopic Stone Extraction

Choledocholithiasis With Acute Cholangitis

China
Janssen Research & Development, LLC

Recruiting

A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer (MoonRISe-1)

Non-Muscle Invasive Bladder Cancer

United States, Israel
Changchun GeneScience Pharmaceutical Co., Ltd.
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Long-term Follow-up Safety of a Single Injection of GenSci094 for Ovarian Stimulation Using Daily Recombinant FSH as Reference

Infertility

China
Guangzhou Institute of Respiratory Disease

Recruiting

Oral Chemotherapeutic Drugs Were Analyzed in Patients With Driver Gene Negative Locally Advanced/Advanced Non-small Cell Lung Cancer With PS Score 2 A Prospective, Single-arm, Multicenter, Observational Study on the Efficacy and Safety of Radiochemotherapy Combined With PD-1 Inhibitor

Non-small Cell Lung Cancer Stage IIIB/IV

China
Hospital del Mar

Not yet recruiting

Analysis of the Acute Mesenteric Ischemia in a Single Institution Over 10 Years (AMI_HMAR)

Acute Mesenteric Ischemia
Merck Sharp & Dohme LLC

Recruiting

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

Breast Neoplasms

Israel, United States, Taiwan, Hong Kong, Korea, Republic of, Switzerland, Costa Rica
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

Impact of Single- Versus Double-layer Hysterotomy Closure on Cesarean Niche Development: a Randomized Controlled Trial

Cesarean Section Complications | Cesarean Section; Dehiscence | Uterine Bleeding | Uterus; Scar | Uterus Abnormal

Italy
Centre Hospitalier Universitaire de Nīmes

Recruiting

Calcified Cerebral Embolism: a Descriptive Study in a Large Single Center Cohort (CCE Cohorte)

Calcified Cerebral Embolism

France
OX2 Therapeutics

Recruiting

CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults

Diffuse Midline Glioma, H3 K27M-Mutant | Recurrent High Grade Glioma

United States
Lebanese University
Haykel Hospital

Recruiting

Precision Therapy for Solid Tumors: Synergistic CDK4/6 Inhibition and Anti-VEGF Targeting LncRNA (PTST_PALBEVA)

Cancer | Breast Cancer | Colorectal Cancer | Ovarian Cancer | Lung Cancer | Chemotherapy | Solid Tumor | Immunotherapy | Targeted Therapy | Precision Therapy

Lebanon
Ankara City Hospital Bilkent

Recruiting

Comparison of Airway Management With Bronchial Blocker and Double-Lumen Tube in Single-Lung Ventilation

Coronary Arteriosclerosis | One-lung Ventilation | Heart Valvular Disease

Turkey
A.O.U. Città della Salute e della Scienza

Recruiting

Effectiveness of a Single Dose of Betamethasone in Children With Symptomatic Adenovirus Infection (Adeno-beta)

Adenovirus

Italy
Igdir University

Not yet recruiting

The Effect of Dual Task on Manual Ability Performance in Children With Cerebral Palsy

Cerebral Palsy
Longbio Pharma

Recruiting

A Study of Single and Multiple Doses of LP-005 in Healthy Adult Participants

Paroxysmal Nocturnal Hemoglobinuria (PNH)

China

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