Search clinical trials for: Single arm

Total 18953 results

University of Michigan
Reuben Phoenix Schostak Fontan Wellness Project Fund

Recruiting

WE BEAT - HEART Club Fontan Wellness Project: A Virtual Resilience Promotion and Frailty Prevention Program

Frailty | Fontan Physiology | Single Ventricle Heart Disease

United States
Changchun BCHT Biotechnology Co.

Recruiting

To Evaluate the Safety and Primary Immunogenicity of Cell-free (Three-component) Combination Vaccine for Phase I Immunogenicity in Children and Infants

Safety、Immunogenicity

China
Szeged University

Recruiting

Open Label Single Arm Proof of Concept Trial to Evaluate the Efficacy and Safety of Cytori Celution System in Chronic Non-Healing Venous Leg Ulcers

Mesenchymal Stem Cells | Venous Leg Ulcer | Autologous Adipose Stromal Vascular Fraction | Adipose-Derived Mesenchymal Stem Cells

Hungary
Shanghai Mental Health Center

Recruiting

Transcranial Alternating Current Stimulation (tACS) for Auditory Hallucinations

Schizophrenia

China
Nanjing First Hospital, Nanjing Medical University

Recruiting

A Prospective Phase II Efficacy and Safety Study of Anlotinib in Metastatic or Locally Advanced Pheochromocytoma/ Paraganglioma : Open-label Single-arm, Exploratory Trial (EASOAIPPGL)

Advanced or Metastatic Paraganglioma/ Pheochromocytoma

China
Shield Therapeutics

Recruiting

Evaluate the Safety and Efficacy of Ferric Maltol Oral Suspension vs. Ferrous Sulfate Oral Liquid in Children and Adolescents Aged 2 to 17 Years With Iron-deficiency Anaemia, With a Single Arm Study in Infants Aged 1 Month to Less Than 2 Years (FORTIS)

Iron-deficiency | Anemia

United States, United Kingdom, Puerto Rico
Zhuhai Tonbridge Medical Tech. Co., Ltd.

Not yet recruiting

A Single-Arm Objective Performance Criteria Trial For Intracranial Thrombus Aspiration Catheter

Acute Ischemic Stroke

China
Genmab
Merck Sharp & Dohme LLC; BioNTech SE

Recruiting

Safety and Efficacy Study of GEN1046 as a Single Agent or in Combination With Pembrolizumab for Treatment of Recurrent (Non-small Cell) Lung Cancer

Non Small Cell Lung Cancer Metastatic

United States, Spain, Netherlands, Italy, France, United Kingdom, Poland, Germany, Portugal
Neovasc Inc.
Shockwave Medical, Inc.

Recruiting

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II (COSIRA-II)

Refractory Angina

United States, Canada
M.D. Anderson Cancer Center

Recruiting

A Phase 1 With Extension Cohort, Single Arm, Single Center, Open Label Trial of Belantamab Mafodotin for the Treatment of High-Risk Smoldering Multiple Myeloma

Myeloma

United States
University Hospital, Essen

Recruiting

Phase Ib/II Single-arm Study of mFOLFOX6, Bevacizumab and Atezolizumab in Advanced Biliary Tract Cancer (COMBATBIL)

Biliary Tract Cancer

Spain, Germany
Ethicon Endo-Surgery

Recruiting

A Prospective, Single-Arm Multi-Center Study of the HARMONIC® 1100 Shears in Select Devices

Pediatric Procedures | Adult Hepato-pancreato-biliary (HPB) Procedures | Adult Lower Gastrointestinal Procedures | Adult Gastric Procedures | Adult Gynecological Procedures | Adult Urological Procedures | Adult Thoracic Procedures

United States, Canada, United Kingdom
Tongji Hospital
National Natural Science Foundation of China

Recruiting

Neoadjuvant Immunotherapy (PD-1 / PD-L1) Combined With Chemotherapy for Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma: a Single Center, Prospective, Open, One Arm Exploratory Clinical Study (NICCE)

Esophageal Squamous Cell Carcinoma | Neoadjuvant Therapies

China
Direction Centrale du Service de Santé des Armées

Not yet recruiting

Clinical Impact and Neuro-functional Substrate of Immersive Virtual Reality Sports Practice on Depression (DEPRIV)

Depression

France
Eye & ENT Hospital of Fudan University
Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Recruiting

Single Arm Study of Induction Chemoradiotherapy Combined With Surgery in the Treatment of Locally Advanced SNMM (SNMM)

Mucosal Melanoma | Sinonasal Melanoma

China
HonorHealth Research Institute
NovoCure Ltd.

Recruiting

Single Arm Trial of Tumor-Treating Fields in Combination With Nivolumab and Ipilimumab in Metastatic Uveal Melanoma

Uveal Melanoma

United States
Lepu Medical Technology (Beijing) Co., Ltd.

Not yet recruiting

Optimized Antiplatelet Therapy in Patients With CHD After Implantation of NeoVas™ BRS System

Coronary Heart Disease

China
Cancer Hospital of Guangxi Medical University

Recruiting

Concurrent Chemoradiotherapy With Toripalimab for Local-regional Recurrent Nasopharyngeal Carcinoma: a Prospective, Single-arm, Phase II Trial

Nasopharyngeal Carcinoma | Recurrent Nasopharyngeal Squamous Cell Carcinoma | Toripalimab

China
The University of Texas Health Science Center,...

Recruiting

A Single-arm Phase II Study to Evaluate the Safety and Efficacy of Combination Systematic Chemotherapy and Multiple Rounds of Endoscopic Ultrasound-guided Radiofrequency Ablation in Pancreatic Cancer (PANCARDINAL-1)

Pancreatic Ductal Adenocarcinoma (PDAC)

United States
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Application of Pablizumab Combined With Apatinib and Chemotherapy in Resectable Non-small Cell Lung Cancer： A Prospective, Single Arm, Single Center Phase II Clinical Study of Neoadjuvant Therapy

Non-small Cell Lung Cancer

China
Fudan University

Recruiting

Single Arm Phase II Study of Fractionated Stereotatic Radiation Therapy (FSRT) for Bone Metastases in Breast Cancer

Breast Cancer | Bone Metastases

China
QualiMed Innovative Medizinprodukte GmbH

Recruiting

UNITY-B A Prospective, Multicentric, Single-arm Study to Evaluate the Safety and Efficacy of the UNITY-B Biodegradable Balloon-Expandable Biliary Stent System in Subjects With Biliary Strictures

Bile Duct Diseases | Biliary Obstruction | Bile Duct Stricture

Hong Kong, India, Malaysia
Zhuhai Tonbridge Medical Tech. Co., Ltd.

Recruiting

A Single-arm Trial of the Flow Diverter (Tonbridge) For Endovascular Treatment of Intracranial Aneurysms

Intracranial Aneurysm

China
West China Hospital

Recruiting

Single-arm, Multi-center Clinical Study of Pyrotinib Maleate Tablets Combined With Albumin-bound Paclitaxel and Trastuzumab in Neoadjuvant Treatment of Her2-positive Early or Locally Advanced Breast Cancer

Breast Cancer

China
Wuhan Union Hospital, China

Recruiting

The Efficacy and Safety of TACE, Lenvatinib and Camrelizumab in the Treatment of BCLC Stage B/C Hepatocellular Carcinoma: a Single-arm, Single-center, Open-label Study

Hepatocellular Carcinoma

China
Shanghai Zhongshan Hospital

Recruiting

A Prospective, Two-center, Single Arm Phase II Clinical Study to Evaluate Safety and Effectiveness of Ablation Therapy in the Treatment of Lung Cancer Presenting as Ground-glass Nodules

Progression

China
Seoul National University Hospital

Recruiting

Talazoparib in Advanced Breast Cancer Patients With Homologous Recombinant Deficiency

Advanced Breast Cancer

Korea, Republic of
Sun Yat-sen University

Recruiting

An Open-label, Single Arm, Phase II Trial of Niraparib in Combination With Anti-PD1（Programmed Cell Death Protein 1） Antibody in Recurrent/ Advanced Stage Endometrial Cancer Patients

Recurrent/ Advanced Stage Endometrial Cancer Patients

China
IRCCS San Raffaele
Bristol-Myers Squibb

Recruiting

An Open Label, Single-arm, Phase 2 Study of Neoadjuvant Nivolumab and Nab-paclitaxel Before Radical Cystectomy for Patients With Muscle-invasive Bladder Cancer (NURE-Combo) (NURE-Combo)

Muscle-Invasive Bladder Carcinoma

Italy
King's College London
University College, London

Recruiting

Online Singing Interventions for Postnatal Depression in Times of Social Isolation: a Single Arm Study (SHAPER-PNDO)

Social Isolation | Postnatal Depression

United Kingdom
Tianjin Medical University Cancer Institute and...
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

Efficacy and Safety of Anlotinib, Irinotecan and Temozolomide in the Treatment of Refractory or Recurrent Neuroblastoma in Children: an Open, Single Arm, Single Center, Phase II Clinical Study

Refractory or Recurrent Neuroblastoma in Children
Atlanta Diabetes Associates
Medtronic

Recruiting

Evaluation of Medtronic DUO Extended Set

Diabetes Mellitus, Type 1

United States
Sun Yat-sen University

Recruiting

PD-1 Antibody and Lenvatinib Plus TACE-HAIC for Potential Resectable HCC: a Single-arm, Phase 2 Clinical Trial (PLATIC)

Hepatocellular Carcinoma

China
Sun Yat-sen University

Recruiting

Transarterial Infusion of PD-1 Antibody Plus TACE-HAIC for Unresectable HCC: a Single-arm, Phase 2 Clinical Trial (AIPD-1)

Hepatocellular Carcinoma

China
liberDi Ltd.

Recruiting

A Single Arm, Multi-Center Study To Evaluate The Intelligent Dialysis Assistant (IDA)

Chronic Kidney Disease Stage 5

Israel
Sun Yat-sen University

Recruiting

TACE Combined With Sintilimab Plus Bevacizumab Biosimilar in Hepatocellular Carcinoma (BCLC-C Stage ): a Prospective Single-arm Phase II Clinical Study (T-Double)

Hepatocellular Carcinoma

China
Shanghai Pulmonary Hospital, Shanghai, China

Recruiting

Neoadjuvant Durvalumab/Anlotinib /Chemotherapy Plus Curative Resection in Stage III Non-Small-Cell Lung Cancer : A Single-arm Phase II Study

Non Small Cell Lung Cancer

China
First People's Hospital of Hangzhou

Recruiting

A Single-arm, Phase Ⅱ Clinical Trial of Anlotinib Hydrochloride Combined With Irinotecan or Docetaxel for Second Line Treatment of Nonsensitive Relapsed Small-cell Lung Cancer

Relapsed Small Cell Lung Cancer | Anlotinib

China
Peking Union Medical College Hospital

Recruiting

Zanuburutinib in Relapsed and Refractory iMCD: a Prospective, Single-center, Single-arm Trial (iMCD)

Idiopathic Multicentric Castleman's Disease

China
QualiMed Innovative Medizinprodukte GmbH

Recruiting

A PROSPECTIVE, MULTI-CENTER, SINGLE-ARM, POST MARKET OBSERVATIONAL STUDY TO EVALUATE THE SAFETY AND CLINICAL PERFORMANCE OF THE ARCHIMEDES BIODEGRADABLE BILIARY AND PANCREATIC STENT (AM GI Registry)

Obstructed Biliary and Pancreatic Duct

Spain, Israel, Finland, Italy, Slovenia, Germany
Allevio Pain Management Clinic

Recruiting

Frozen Shoulder Single Arm Prospective Study

Frozen Shoulder

Canada
Yi Luo

Recruiting

A Single-arm Trial of Prophylactic Tocilizumab for Acute GVHD Prevention After Haploidentical HSCT.

Leukemia | Graft-versus-host-disease

China
California Institute of Renal Research

Recruiting

A Single Arm sTudy to Evaluate the Effectiveness of EndoAVF in a Pre-dialysis Population (STEP Study)

CKD Stage 4 | CKD Stage 5 | CKD Stage 3

United States
Ruijin Hospital
The First Affiliated Hospital with Nanjing Medical University; First Affiliated... and other collaborators

Not yet recruiting

Asymmetric DBS for PD : A Multicenter, Prospective, Single Arm, Open Label Study (ADP)

Parkinson Disease
Medtronic - MITG

Recruiting

Prospective, Multi-center, Single-arm, Observational Study. US FDA 522 Pediatric Post Market Surveillance Study.

Acute Kidney Injury | Fluid Overload

United States
Malmö University
Kronoberg County Council; County Council of Halland, Sweden; Norrbottens County... and other collaborators

Recruiting

One vs Two Visits Root Canal Treatments in Infected Teeth

Pain | Apical Periodontitis | Tooth Loss | Dental Pulp Necrosis

Sweden
UNC Lineberger Comprehensive Cancer Center
Fogarty International Center of the National Institute of Health

Recruiting

Safety and Efficacy of Rituximab for Treatment of Multicentric Castleman Disease in Malawi

Multicentric Castleman Disease

Malawi
Dana-Farber Cancer Institute
Genentech, Inc.

Recruiting

A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer (ADEPT)

Breast Cancer | HER2-positive Breast Cancer | Hormone Receptor Positive Breast Cancer | Invasive Carcinoma of the Breast | Node Negative Breast Cancer | Micrometastasis Breast Cancer

United States
Yunfei Yuan

Recruiting

TACE-HAIC Plus Lenvatinib for Patients With Unresectable HCC: an Open-label, Single-arm, Phase 2 Trial (Thalen)

Hepatocellular Carcinoma | Transarterial Chemoembolization

China
National University Hospital, Singapore

Recruiting

A Single Arm, Phase Ib/II Trial of Single Agent Pacritinib in Patients With 1q21.3 Amplified Solid Tumors Enriching for Interleukin-1 Receptor-associated Kinase 1 Pathway Activation (PAIR)

Breast Cancer

Singapore

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