Search clinical trials for: actionable alterations
Total 455 results
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Centre Leon BerardNational Cancer Institute, FranceRecruitingMalignant Solid NeoplasmsFrance
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National Cancer Institute (NCI)RecruitingMesothelioma | Thymus Tumors | Adoptive Cellular Therapy | Genitourinary Cancers | Lung CancersUnited States
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Janssen Research & Development, LLCActive, not recruitingAdvanced Solid TumorFrance, United States, Japan, Belgium, United Kingdom, Germany, Taiwan, China, Korea, Republic of, Poland, Italy, Spain, Australia, Brazil, Argentina
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Queen Mary University of LondonHoffmann-La Roche; MedSIR; Westdeutsche Studiengruppe GmbH (WSG)Active, not recruitingTriple Negative Breast CancerUnited Kingdom
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Timothy Burns, MD, PHDNovartisWithdrawnNon-small Cell Lung CancerUnited States
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University Hospital, AngersCompletedCarpal Tunnel Syndrome | Chronic Low Back Pain | Musculoskeletal Disorder | Rotator Cuff TendinitisFrance
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M.D. Anderson Cancer CenterBayerActive, not recruitingOvarian Cancer | Endometrial CancerUnited States
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UNICANCERHoffmann-La Roche; National Cancer Institute, France; Fondation ARCActive, not recruitingSolid Tumors | Hematologic Cancers | Metastatic CancersFrance
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Selcuk UniversityCompletedBruxism | Anxiety State | Tryptophan Metabolism AlterationsTurkey
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BioMed Valley Discoveries, IncTerminatedAdvanced Solid Tumor | MAP2K1 Gene Mutation | BRAF Gene Mutation | MEK Mutation | BRAF Gene Alteration | MEK Alteration | MAP2K1 Gene Alteration | MAP2K2 Gene Mutation | MAP2K2 Gene AlterationUnited States
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Aadi Bioscience, Inc.Active, not recruitingMalignant Solid Neoplasm | Neoplasms | Cancer | Neoplasm Metastasis | Solid Tumor | Metastatic Cancer | Metastasis | Advanced Solid Tumor | Metastatic Solid Tumor | Advanced Cancer | Tumor | Malignant Neoplasm | Malignant Tumor | Tumors | Cancer Metastatic | Tumor, Solid | Malignant Solid Tumor | TSC | TSC1 | TSC2 | Metastatic NeoplasmUnited States, Korea, Republic of, Puerto Rico
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National Cancer Institute (NCI)Active, not recruitingMalignant Solid Neoplasm | Recurrent Melanoma | Recurrent Ependymoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Glioma | Recurrent Medulloblastoma | Recurrent Neuroblastoma | Recurrent Non-Hodgkin... and other conditionsUnited States, Puerto Rico
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National Cancer Institute (NCI)Active, not recruitingRecurrent Childhood Ependymoma | Advanced Malignant Solid Neoplasm | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Glioma | Recurrent Medulloblastoma | Recurrent Neuroblastoma | Recurrent Non-Hodgkin... and other conditionsUnited States, Puerto Rico
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National Cancer Institute (NCI)Children's Oncology GroupActive, not recruitingRefractory Lymphoma | Refractory Malignant Solid Neoplasm | Recurrent Ependymoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Histiocytic and Dendritic Cell Neoplasm | Recurrent Langerhans Cell Histiocytosis | Recurrent Lymphoma | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant... and other conditionsUnited States, Puerto Rico, Australia
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M.D. Anderson Cancer CenterMerck Sharp & Dohme LLC; AstraZenecaActive, not recruitingProstate Carcinoma | Prostate Cancer AggressivenessUnited States
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First Affiliated Hospital of Zhejiang UniversityCompletedDisorder of ConsciousnessChina
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Kinnate BiopharmaActive, not recruitingIntrahepatic Cholangiocarcinoma | Urothelial Carcinoma | Solid Tumor, AdultUnited States, Korea, Republic of, Taiwan, China, Denmark, Spain
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M.D. Anderson Cancer CenterWithdrawn
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingAnatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditionsUnited States
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M.D. Anderson Cancer CenterAstraZenecaActive, not recruitingMalignant Neoplasms of Female Genital Organs | Malignant Neoplasm of Breast | Malignant Neoplasms of Thyroid and Other Endocrine Glands | Malignant Neoplasms of Digestive Organs | Malignant Neoplasms of Male Genital OrgansUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Metastatic Malignant Neoplasm | Advanced Malignant Neoplasm | Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | PALB2 Gene Mutation | ATM Gene MutationUnited States
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Memorial Sloan Kettering Cancer CenterColumbia University; Icahn School of Medicine at Mount Sinai; Weill Medical College...Active, not recruitingKidney Cancer | Breast Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Bladder Cancer | Colon CancerUnited States
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Centre Hospitalier Universitaire DijonWithdrawn
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Navire Pharma Inc., a BridgeBio companyActive, not recruitingTumor, SolidUnited States
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QED Therapeutics, Inc.Helsinn Healthcare SATerminatedUpper Tract Urothelial Carcinomas | Urothelial Bladder CancerUnited States, France, Canada, Spain, Italy, Belgium, Germany, Netherlands, United Kingdom, Bulgaria, Greece
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Robert Tighe, MDNational Institutes of Health (NIH); Ohio State UniversityCompletedHealthyUnited States
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Genentech, Inc.CompletedAdvanced Unresectable or Metastatic Solid MalignancyUnited States
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University of Michigan Rogel Cancer CenterActive, not recruiting
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UNICANCERPfizer; National Cancer Institute, France; Fondation ARCCompletedMetastatic Cancer | Solid Tumors | Hematologic CancersFrance
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Genentech, Inc.CompletedNeoplasms | Bladder Cancer | Solid Tumors | Biliary Cancer | Salivary CancerUnited States
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Academic and Community Cancer Research UnitedNational Cancer Institute (NCI)Active, not recruitingMetastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC v8 | Stage IIIC Colorectal Cancer AJCC v8 and other conditionsUnited States
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Institut CurieActive, not recruiting
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University of Wisconsin, MadisonNational Institute on Deafness and Other Communication Disorders (NIDCD)Completed
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Children's Mercy Hospital Kansas CityActive, not recruiting
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Memorial Sloan Kettering Cancer CenterXcovery Holding Company, LLCActive, not recruiting
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Institut CurieCompletedMetastatic and/or High Risk Solid Tumor of ChildrenFrance
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Xiangya Hospital of Central South UniversityCompleted
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Incyte CorporationActive, not recruitingGlioblastoma | Adult-type Diffuse GliomasUnited States, Spain, Italy, United Kingdom, Germany, Japan, France, Netherlands, Denmark
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New Mexico Cancer Care AllianceActive, not recruiting
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National Cancer Center, JapanEisai Co., Ltd.Active, not recruitingAdvanced or Recurrent Solid Tumors | FGFR Gene AlterationsJapan
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United TherapeuticsCompletedPulmonary Arterial HypertensionUnited States
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Fusion Pharmaceuticals Inc.TerminatedBreast Cancer | Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Lung Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma | Liver Cancer | Bladder Carcinoma | Susceptible FGFR3 Genetic Alterations | FGFR3 | FGFR3 Overexpression | FGFR3 Receptor | FGFR3 Protein OverexpressionUnited States, Australia
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Wake Forest University Health SciencesNational Cancer Institute (NCI)TerminatedLymphoma | Multiple Myeloma | Solid Tumor | Malignant Neoplasm | Mutation AbnormalityUnited States
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SCRI Development Innovations, LLCBayer; Boehringer Ingelheim; Exelixis; Foundation MedicineCompletedNon-small Cell Lung Carcinoma | Urothelial Carcinoma | Gastrointestinal Carcinoma, Non-colon | Upper Aerodigestive Tract CarcinomaUnited States
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University of ChicagoActive, not recruitingCritical Illness | MicrobiomeUnited States
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Qilu Hospital of Shandong UniversityCompletedPancreatic Ductal Adenocarcinoma (PDAC)China
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University Children's Hospital, ZurichUniversity of Zurich; Psychiatric University Hospital, ZurichCompletedMeningomyeloceleSwitzerland
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Erasca, Inc.Active, not recruitingAdvanced or Metastatic Solid TumorsUnited States, Australia
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Matthew GalskyIcahn School of Medicine at Mount Sinai; AstraZenecaCompletedMetastatic Urothelial CancerUnited States
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Assistance Publique - Hôpitaux de ParisCompletedGlioma | Non Small Cell Lung Cancer | Non Hodgkin LymphomaFrance