Search clinical trials for: cancer of rectum

Total 440798 results

Zealand University Hospital

Recruiting

NEOadjuvant Chemotherapy Only Compared With Standard Treatment for Locally Advanced Rectal Cancer (NEOLAR)

Intestinal Neoplasms | Colorectal Cancer | Rectal Cancer | Rectal Neoplasms | Colorectal Neoplasm | Chemotherapy Effect | Intestinal Disease

Denmark
Peking University People's Hospital
Xijing Hospital; Beijing Friendship Hospital; Peking Union Medical College Hospital and other collaborators

Recruiting

Effect of Concurrent Capecitabine-based Long-term Radiotherapy Followed by XELOX Plus TME in Patients With High Risk Rectal Cancer: a Multi-centers, Randomized Controlled, Open-Label Trial (EXPLORE)

Rectal Cancer | Pathological Complete Response | Disease Free Survival

China
Takayuki Yoshino
Ono Pharmaceutical Co. Ltd

Recruiting

Study to Nivolumab Following Preoperative Chemoradiotherapy

Cancer of Rectum

Japan
University of Birmingham

Recruiting

Can we Save the Rectum by Watchful Waiting or TransAnal Surgery Following (Chemo)Radiotherapy Versus Total Mesorectal Excision for Early REctal Cancer? (STAR-TREC)

Adenocarcinoma of the Rectum

Denmark, Netherlands, United Kingdom, Belgium, Sweden
Hôpital Edouard Herriot
Medtronic; National Cancer Institute, France

Recruiting

Efficacy of Colonoscopy, Colon Capsule and Fecal Immunological Test for Colorectal Cancer Screening (FAMCAP)

Colon Cancer | Rectum Cancer

France
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Optimization of Preoperative Treatment in Locally Advanced Rectal Cancer (STELLAR)

Cancer, Rectum

China
University of Utah
Washington University School of Medicine; Cedars-Sinai Medical Center; German... and other collaborators

Recruiting

ColoCare Study - Colorectal Cancer Cohort

Colorectal Cancer

United States, Germany
Third Affiliated Hospital, Sun Yat-Sen University
First Affiliated Hospital, Sun Yat-Sen University; Nanfang Hospital of Southern... and other collaborators

Recruiting

Multicenter Study on Laparoscopic Versus Open PANP-TME for Male Mid-low Rectal Cancer Patients

Rectum Neoplasms

China
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

Laparoscopic Versus Open PANP-TME for Male Mid-low Rectal Cancer Patients

Rectum Neoplasms

China
M.D. Anderson Cancer Center

Recruiting

Evaluation of Quality of Life and Utilities Following Surgical Treatment of Stage I-IV Rectal Cancer

Stage III Rectal Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage IIIC Rectal Cancer AJCC v8 | Stage IV Rectal Cancer AJCC v8 | Stage IVA Rectal Cancer AJCC v8 | Stage IVB Rectal Cancer AJCC v8 | Stage IVC Rectal Cancer AJCC v8 | Rectal Adenocarcinoma | Stage... and other conditions

United States
University of Erlangen-Nürnberg Medical School

Recruiting

Neoadjuvant Chemoradiation With 5-FU(or Capecitabine) and Oxaliplatin Combined With Hyperthermia in Rectal Cancer (HyRec)

Rectal Cancer

Germany
Novartis Pharmaceuticals

Active, not recruiting

A Study of Select Drug Combinations in Adult Patients With Advanced/Metastatic BRAF V600 Colorectal Cancer

BRAF V600 Colorectal Cancer

Belgium, Germany, Netherlands, Spain, Singapore, Australia, United Kingdom, Israel, Canada, United States
National Cancer Institute (NCI)

Active, not recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Glioma | Hematopoietic and Lymphoid Cell Neoplasm | Melanoma | Lymphoma | Multiple Myeloma | Recurrent Ovarian Carcinoma | Breast Carcinoma | Recurrent Head and Neck Carcinoma | Recurrent Lung Carcinoma | Recurrent Skin Carcinoma | Gastric Carcinoma | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory... and other conditions

United States, Puerto Rico, Guam
Centre Oscar Lambret
INSERM 1003-1; L'Institut des sciences moléculaires (iSm2 UMR CNRS 7313)

Active, not recruiting

Association Between the Composition of the Intestinal Microbiota and Tumor Response in Locally Advanced Rectal Cancer (Neo-Flo-Rect)

Cancer of Rectum

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

LY3214996 and Cetuximab Alone or in Combination With Abemaciclib for the Treatment of Unresectable or Metastatic Colorectal Cancer

Recurrent Colorectal Carcinoma | Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 and other conditions

United States
National Cancer Institute (NCI)

Terminated

Talimogene Laherparepvec, Chemotherapy, and Radiation Therapy Before Surgery in Treating Patients With Locally Advanced or Metastatic Rectal Cancer

Metastatic Rectal Adenocarcinoma | Rectal Adenocarcinoma | Stage III Rectal Cancer AJCC v7 | Stage IIIA Rectal Cancer AJCC v7 | Stage IIIB Rectal Cancer AJCC v7 | Stage IIIC Rectal Cancer AJCC v7 | Stage IV Rectal Cancer AJCC v7 | Stage IVA Rectal Cancer AJCC v7 | Stage IVB Rectal Cancer AJCC v7 | Locally...

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Panitumumab, Regorafenib, or TAS-102, in Treating Patients With Metastatic and/or Unresectable RAS Wild-Type Colorectal Cancer

Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); Texas A&M University

Completed

Fiber and Fish Oil Supplements for the Prevention of Colorectal Cancer

Healthy Subject

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combined With Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver

Colorectal Cancer | Metastatic Cancer

United States
Voronezh N.N. Burdenko State Medical Academy
Voronesh Regional Clinical Hospital #1

Completed

Procedure RACHEL in Complex Treatment of Rectal Cancer (RACHEL)

Rectal Cancer T3-4N0-2M0

Russian Federation
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Genetic Mutations in Blood and Tissue Samples in Predicting Response to Treatment in Patients With Locally Advanced Rectal Cancer Undergoing Chemoradiation

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Recurrent Rectal Cancer

United States
Daorong Wang

Completed

Assessing the Benefits of Robotic and Laparoscopic Surgery for Mid and Low Rectal Cancer in Patients: The Charlson Comorbidity Index (CCI)

Laparoscopic | Robotic | Anterior Resection for Rectal Cancer

China
M.D. Anderson Cancer Center
Bayer; Xencor, Inc.

Withdrawn

Regorafenib and XmAb20717 in Treatment of High-risk Patients With Colorectal Cancer With Radiographic Occult Molecular Residual Disease After End of Established Definitive Therapy (RX-CROME)

Colorectal Cancer | Colon Cancer | Rectum Cancer

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Trametinib and Trifluridine and Tipiracil Hydrochloride in Treating Patients With Colon or Rectal Cancer That is Advanced, Metastatic, or Cannot Be Removed by Surgery

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Metastatic Colorectal Carcinoma | Stage III Colon Cancer AJCC v7 | Stage III Rectal Cancer AJCC v7 | Stage IIIA Colon Cancer AJCC v7 | Stage IIIA Rectal Cancer AJCC v7 | Stage IIIB Colon... and other conditions

United States
Washington University School of Medicine

Active, not recruiting

Non-Operative Management and Early Response Assessment in Rectal Cancer (NOM-ERA)

Adenocarcinoma of the Lower Rectum

United States
Washington University School of Medicine

Active, not recruiting

Endoscopic Optical Coherence Tomography for Screening and Diagnosis of Colorectal Precancerous and Malignant Polyps

Rectal Cancer | Colon Cancer | Cancer of the Colon | Cancer of the Rectum | Precancerous Polyp | Malignant Polyp

United States
NuCana plc

Active, not recruiting

A Study of NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer

Colorectal Neoplasms | Colorectal Cancer | Colorectal Cancer Metastatic | Colorectal Adenocarcinoma | Neoplasm, Colorectal

United States, Spain, United Kingdom, Italy, Germany, France
NuCana plc

Completed

A Safety, Pharmacokinetic and Efficacy Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer Treatment

Colorectal Neoplasms | Colorectal Cancer | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal

United States, France, United Kingdom
University of Aarhus
Danish Cancer Society

Completed

Healing of Rectal Anastomosis Sealed With a Concentrate Derived From the Patient's Blood, After Rectal Cancer Surgery (OBANORES)

Rectal Cancer | Anastomotic Leak Rectum | Anastomotic Leakage

Denmark
Dublin City University
Royal College of Surgeons, Ireland; Mater Misericordiae University Hospital

Active, not recruiting

Perioperative Exercise and Nutritional Optimisation Prehabilitation Before Surgery for Patients With Peritoneal Malignancy (PANO)

Ovarian Cancer | Colon Cancer | Appendix Cancer | Rectum Cancer | Peritoneal Malignancy

Ireland
University of Colorado, Denver
Bristol-Myers Squibb; National Cancer Institute (NCI); Criterium, Inc.; Exelixis

Active, not recruiting

Study of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancer

Colorectal Cancer | Rectal Cancer | Colon Cancer | Colorectal Adenocarcinoma | Rectal Adenocarcinoma | Rectum Cancer | Colon Adenocarcinoma

United States
Sixth Affiliated Hospital, Sun Yat-sen University

Active, not recruiting

Deep Learning Based MRI Radiomics in Predicting the Clinical Risk of Locally Advanced Rectal Cancer

Locally Advanced Rectal Carcinoma
Sixth Affiliated Hospital, Sun Yat-sen University

Completed

Assessment of Efficacy of Neoadjuvant Therapy in Locally Advanced Rectal Cancer

Locally Advanced Rectal Carcinoma
Hospital Central de la Defensa Gómez Ulla
Clinica Universidad de Navarra, Universidad de Navarra

Enrolling by invitation

Patient Reported Outcomes Following Cancer of the Rectum (PROCaRe)

Rectal Cancer | PROM | Functional Bowel Disorder

Spain
Institut Cancerologie de l'Ouest
Fondation ARC

Active, not recruiting

64Cu-ATSM PET/CT in Rectum Cancer (TEP 64Cu-ATSM-Rectum)

Rectal Cancer

France
National Cancer Institute (NCI)

Active, not recruiting

Ropidoxuridine in Treating Patients With Advanced Gastrointestinal Cancer Undergoing Radiation Therapy

Stage III Pancreatic Cancer AJCC v6 and v7 | Stage IV Pancreatic Cancer AJCC v6 and v7 | Stage IV Esophageal Cancer AJCC v7 | Stage IV Gastric Cancer AJCC v7 | Stage III Liver Cancer | Stage IV Liver Cancer | Stage III Colon Cancer AJCC v7 | Stage III Rectal Cancer AJCC v7 | Stage IIIA Colon Cancer... and other conditions

United States
Gruppo Oncologico del Nord-Ovest

Active, not recruiting

Short-course Radiotherapy Followed by Consolidation Chemotherapy. 2021-001206-29 (ShorTrip)

Locally Advanced Rectal Cancer

Italy
Cancer Institute and Hospital, Chinese Academy...

Completed

Constructing a Multimodal Imaging System to Predict the Risk of Heterochronous Metastasis of Rectal Cancer (MIS-MRC)

Locally Advanced Rectal Cancer | Distant Metastasis

China
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Metastatic Cancer

Melanoma | Breast Cancer | Colorectal Cancer | Lung Cancer | Bone Cancer | Rectal Cancer | Uterine Sarcoma | Colon Cancer | Ovarian Sarcoma | Eye Cancer | Adult Soft Tissue Sarcoma

United States
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Colon, Pancreatic, or Lung Cancer

Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Extensive Stage Small Cell Lung Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage II Pancreatic Cancer | Stage IVA Pancreatic Cancer | Stage IVB Pancreatic Cancer | Stage I Pancreatic Cancer | Stage II Non-small Cell Lung Cancer | Stage III Colon Cancer and other conditions

United States
Bristol-Myers Squibb
Novartis

Active, not recruiting

An Investigational Immuno-therapy Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Cancer of the Colon or Rectum That Has Spread (CheckMate 9N9)

Colorectal Cancer | Colorectal Neoplasm | Colorectal Tumors | Colorectal Carcinoma

Italy, United States, Canada, Spain, Argentina, Australia, Belgium, Chile, Czechia, Germany
Intuitive Surgical

Active, not recruiting

da Vinci SP® Investigational Device Exemption Study in Colorectal Procedures

Colorectal Cancer | Benign or Malignant Rectal or Colon Tumors

United States, Korea, Republic of
Icahn School of Medicine at Mount Sinai

Active, not recruiting

Rectal Spacer Hydrogel Before Radiation Therapy in Reducing Radiation Dose to the Rectum in Patients With Prostate Cancer

Prostate Cancer

United States
Virginia Commonwealth University

Terminated

Colorectal Health Research Champions

Cancer of Colon | Cancer of Rectum

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

S1613, Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by Surgery

Recurrent Colon Carcinoma | Recurrent Rectal Carcinoma | Rectal Adenocarcinoma | Colon Adenocarcinoma | ERBB2 Gene Amplification | Stage III Colon Cancer AJCC v7 | Stage III Rectal Cancer AJCC v7 | Stage IIIA Colon Cancer AJCC v7 | Stage IIIA Rectal Cancer AJCC v7 | Stage IIIB Colon Cancer AJCC v7 | Stage... and other conditions

United States, Puerto Rico
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Canadian Cancer Trials Group

Active, not recruiting

PROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery

Colorectal Cancer

United States, Canada, Israel, Switzerland
National Cancer Centre, Singapore
University of Sydney; Australasian Gastro-Intestinal Trials Group; INDOX Cancer...

Active, not recruiting

Aspirin for Dukes C and High Risk Dukes B Colorectal Cancers (ASCOLT)

Colorectal Cancer

Australia, Saudi Arabia, India, China, Malaysia, Korea, Republic of, Singapore, Indonesia, New Zealand, Sri Lanka
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Regorafenib, Ipilimumab and Nivolumab for the Treatment of Chemotherapy Resistant Microsatellite Stable Metastatic Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Advanced Colon Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer... and other conditions

United States
Memorial Sloan Kettering Cancer Center
Washington University School of Medicine; University of Miami; The Cleveland... and other collaborators

Active, not recruiting

ICARuS Post-operative Intraperitoneal Chemotherapy (EPIC) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) After Optimal Cytoreductive Surgery (CRS) for Neoplasms of the Appendix, Colon or Rectum With Isolated Peritoneal Metastasis (ICARuS)

Colorectal Cancer | Appendix Cancer

United States
Medical College of Wisconsin
M.D. Anderson Cancer Center; National Cancer Institute (NCI); The University... and other collaborators

Completed

The Prevent Anal Cancer Palpation Study

Anal Cancer

United States

Search clinical trials for: cancer of rectum

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