Search clinical trials for: diffuse midline glioma

Total 6321 results

University Hospital, Tours

Completed

Evaluation of Cognitive and Motor Neurological Disorders in the Short and Long Term After Surgery for the Removal of a Diffuse Low-grade Glioma of the Supplementary Motor Area (POG-C)

Motor Disorders | Low-grade Glioma | Cognitive Disorders

France
Weill Medical College of Cornell University

Terminated

Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22

Glioblastoma Multiforme | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Brain Stem Glioma | Pilomyxoid Astrocytoma | Glioma of Brainstem | Fibrillary Astrocytoma of Brain | Mixed Oligodendroglioma-Astrocytoma

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...

Completed

Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors

Glioblastoma | Malignant Glioma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Astrocytoma, Grade III | Brain Stem Neoplasms, Malignant | Oligodendroblastoma

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Temozolomide and Radiation Therapy in Treating Patients With Gliomas

Brain and Central Nervous System Tumors

United States, Canada
Chimerix

No longer available

Expanded Access Use of ONC201 in a Patient With Diffuse Intrinsic Pontine Gliomas

Glioma

United States
Incyte Corporation

Terminated

Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies

Solid Tumors

United States, Belgium, France
Sumitomo Pharma Co., Ltd.

Completed

A Study of DSP-7888 in Pediatric Patients With Relapsed or Refractory High Grade Gliomas

Glioblastoma | Diffuse Intrinsic Pontine Glioma

Japan
Chimerix

No longer available

Expanded Access to ONC201 for Patients With H3 K27M-mutant and/or Midline High Grade Gliomas

Glioma

United States
Memorial Sloan Kettering Cancer Center
Johns Hopkins University; M.D. Anderson Cancer Center; University of Colorado... and other collaborators

Completed

External Beam Radiation Therapy and Cetuximab Followed by Irinotecan and Cetuximab for Children and Young Adults With Newly Diagnosed Diffuse Pontine Tumors and High-Grade Astrocytomas

Brain Cancer

United States, Canada
Burzynski Research Institute

Suspended

A Study of Atengenal and Astugenal in Diffuse, Intrinsic Pontine Glioma (DIPG)

Diffuse, Intrinsic Pontine Glioma

United States
Sabine Mueller, MD, PhD
Pacific Pediatric Neuro-Oncology Consortium; Midatech Pharma US Inc.

Completed

MTX110 by Convection-Enhanced Delivery in Treating Participants With Newly-Diagnosed Diffuse Intrinsic Pontine Glioma (PNOC015)

Diffuse Intrinsic Pontine Glioma

United States
National Cancer Institute (NCI)

Completed

Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas

High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma

United States
Alaunos Therapeutics

Terminated

A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG

Diffuse Intrinsic Pontine Glioma | Pediatric Brain Tumor

United States
National Cancer Institute (NCI)

Completed

Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Gliosarcoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma

United States, Canada, Australia
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors

Brain Tumors | Metastatic Disease

United States
Celgene

Completed

Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, and Hematologic Malignancies.

Neoplasm Metastasis | Prostate Cancer | Chronic Lymphocytic Leukemia | Glioblastoma Multiforme | Squamous Cell Carcinoma of Head and Neck | Ewing's Osteosarcoma

United States, Spain, France, Germany
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Armodafinil in Treating Fatigue Caused By Radiation Therapy in Patients With Primary Brain Tumors

Fatigue | Cognition Disorders | Brain Tumors | Nervous System Tumors

United States
Paul Graham Fisher
National Cancer Institute (NCI); National Institutes of Health (NIH)

Terminated

Phase I Rindopepimut After Conventional Radiation in Children w/ Diffuse Intrinsic Pontine Gliomas

Brain Cancer | Pontine Tumors | Brain Stem Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors

Malignant Glioma | Recurrent Childhood Ependymoma | Recurrent Medulloblastoma | Recurrent Diffuse Intrinsic Pontine Glioma | Recurrent Atypical Teratoid/Rhabdoid Tumor | Refractory Diffuse Intrinsic Pontine Glioma | CNS Embryonal Tumor, Not Otherwise Specified

United States
Children's Cancer Hospital Egypt 57357

Completed

Prospective Trial of Two Hypofractionated Radiotherapy Regimens Versus Conventional Radiotherapy in Diffuse Brainstem Glioma in Children

Pediatric Brain Stem Glioma

Egypt
Baylor College of Medicine
M.D. Anderson Cancer Center; University of Oklahoma; The University of Texas... and other collaborators

Completed

Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma

Glioblastoma Multiforme | Gliosarcoma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Gliomatosis Cerebri | Brainstem Glioma | Malignant Gliomas | Glial Cell Tumors

United States
National Cancer Institute (NCI)

Completed

Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Oligodendroglioma | Recurrent Adult Brain Neoplasm

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

Proton Beam Radiation Therapy in Treating Patients With Low Grade Gliomas

Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Mixed Glioma | Adult Oligodendroglioma | Adult Pineal Gland Astrocytoma | Recurrent Adult Brain Tumor | Adult Brain Stem Glioma | Adult Grade II Meningioma | Adult Meningeal Hemangiopericytoma | Adult Pineocytoma | Adult Brain Tumor | Adult Melanocytic Lesion

United States
Children's Hospital Medical Center, Cincinnati
Novartis

Terminated

A Phase I/II Study of Ribociclib,a CDK4/6 Inhibitor, Following Radiation Therapy

High Grade Glioma | Diffuse Intrinsic Pontine Glioma | Bithalamic High Grade Glioma

United States
Jonsson Comprehensive Cancer Center

Completed

Vaccine for Patients With Newly Diagnosed or Recurrent Low-Grade Glioma

Adult Diffuse Astrocytoma | Adult Mixed Glioma | Adult Oligodendroglioma | Recurrent Adult Brain Tumor | Adult Oligoastrocytoma

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology; Eastern Cooperative Oncology Group and other collaborators

Completed

Observation or Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Low-Grade Glioma

Brain and Central Nervous System Tumors
Jonsson Comprehensive Cancer Center
Upjohn

Completed

Dalteparin to Prevent Complications in Cancer Patients Receiving Chemotherapy Through a Catheter

Lymphoma | Cervical Cancer | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous/Nonmalignant Condition | Veno-occlusive Disease

United States
Jonsson Comprehensive Cancer Center

Completed

Erlotinib and Sirolimus in Treating Patients With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
Susan Chang
Novartis

Completed

Everolimus in Treating Patients With Recurrent Low-Grade Glioma

Adult Diffuse Astrocytoma | Adult Mixed Glioma | Adult Oligodendroglioma | Adult Subependymal Giant Cell Astrocytoma | Recurrent Adult Brain Neoplasm

United States
Case Comprehensive Cancer Center

Completed

Acute Side Effects in Patients Who Are Undergoing Stereotactic Radiosurgery for Brain Tumors or Other Brain Disorders

Brain and Central Nervous System Tumors | Metastatic Cancer | Radiation Toxicity

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Sodium Stibogluconate and IFNa-2b Followed By CDDP, VLB and DTIC Treating Pts.With Advanced Melanoma or Other Cancers

Stage IV Melanoma

United States
Shenzhen Geno-Immune Medical Institute
Shenzhen Children's Hospital; Shenzhen Hospital of Southern Medical University

Unknown

Immune Modulatory DC Vaccine Against Brain Tumor

Diffuse Intrinsic Pontine Glioma or Glioblastoma

China
University Hospital, Montpellier

Completed

Foci of Tumor Heterogeneity in Diffuse Low-Grade Gliomas (FDLGG)

Glioma

France
NewLink Genetics Corporation

Completed

Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors

Glioma | Glioblastoma Multiforme | Gliosarcoma | Ependymoma | Medulloblastoma | Diffuse Intrinsic Pontine Glioma | Malignant Brain Tumor | Primary CNS Tumor

United States
AbbVie
European Organisation for Research and Treatment of Cancer - EORTC

Completed

Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade Gliomas (INTELLANCE-2)

Glioblastoma

United States, Australia, Austria, Belgium, Canada, Czechia, Finland, France, Germany, Hungary, Ireland, Italy, Korea, Republic of, Mexico, Netherlands, Poland, Singapore, Spain, Switzerland, Taiwan, United Kingdom
University Hospital, Montpellier

Completed

Longitudinal MRI Assessment in Patients With Diffuse Low-grade Gliomas (SPECIFY)

Low-grade Glioma

France
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Bortezomib and Vorinostat as Maintenance Therapy After Autologous Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma

Follicular Lymphoma | Mantle Cell Lymphoma | Non-Hodgkin Lymphoma | B-Cell Non-Hodgkin Lymphoma | Adult Diffuse Large B-Cell Lymphoma | T-Cell Non-Hodgkin Lymphoma

United States
Masonic Cancer Center, University of Minnesota

Terminated

Imiquimod/Brain Tumor Initiating Cell (BTIC) Vaccine in Brain Stem Glioma

Diffuse Intrinsic Pontine Glioma

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Brain and Central Nervous System Tumors

United States
University Hospital, Montpellier

Unknown

Molecular Heterogeneity in Multilobar Low-grade Gliomas

Low-grade Diffuse Glioma

France
Sidney Kimmel Comprehensive Cancer Center at Johns...

Terminated

Pilot Study Using Amide Proton Transfer Magnetic Resonance Imaging Distinguishing Glioma

Glioma | Gliosarcoma

United States
Sanjiv Sam Gambhir
National Cancer Institute (NCI)

Completed

18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy

Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Pancreatic Cancer | Stage IV Pancreatic Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Tongue Cancer | Stage... and other conditions

United States
Karen D. Wright MD
Medical University of South Carolina; Johns Hopkins University; Washington University... and other collaborators

Terminated

Molecularly Determined Treatment of Diffuse Intrinsic Pontine Gliomas (DIPG)

Diffuse Intrinsic Pontine Glioma

United States
University of Michigan Rogel Cancer Center

Withdrawn

A Study of Panobinostat in Combination With Everolimus for Children and Young Adults With Gliomas

Glioma | Diffuse Intrinsic Pontine Glioma

United States
National Cancer Institute (NCI)

Completed

Veliparib, Radiation Therapy, and Temozolomide in Treating Younger Patients With Newly Diagnosed Diffuse Pontine Gliomas

Glioblastoma | Gliosarcoma | Anaplastic Astrocytoma | Untreated Childhood Brain Stem Glioma | Giant Cell Glioblastoma | Untreated Childhood Anaplastic Astrocytoma | Untreated Childhood Giant Cell Glioblastoma | Untreated Childhood Glioblastoma | Untreated Childhood Gliosarcoma | Brain Stem Glioma | Untreated... and other conditions

United States
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Study of Blood and Cheek Cell Samples From Patients With Glioma

Brain and Central Nervous System Tumors

United States
Incyte Corporation

Terminated

An Open-Label, Dose-Escalation Study of INCB054329 in Patients With Advanced Malignancies

Solid Tumors and Hematologic Malignancy

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Solving Kids' Cancer

Completed

Intra-arterial Chemotherapy for the Treatment of Progressive Diffuse Intrinsic Pontine Gliomas (DIPG).

Diffuse Intrinsic Pontine Glioma (DIPG)

United States
St. Jude Children's Research Hospital

Completed

Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants With Diffuse Pontine Glioma (DIPG) and High-Grade Glioma (HGG)

Diffuse Intrinsic Pontine Glioma | High-grade Glioma

United States
European Organisation for Research and Treatment...
Hoffmann-La Roche

Completed

Bevacizumab in Recurrent Grade II and III Glioma (TAVAREC)

Central Nervous System Tumors

Netherlands, France, Switzerland, United Kingdom, Belgium, Germany, Austria, Italy

Search clinical trials for: diffuse midline glioma

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