Search clinical trials for: intrathecal nalbuphine

Total 759 results

Kringle Pharma, Inc.

Recruiting

Phase 3 Study of KP-100IT in Subjects With Acute Spinal Cord Injury

Acute Spinal Cord Injury

Japan
Hui Bu

Not yet recruiting

Efficacy and Safety of Durvalumab in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

Leptomeningeal Metastasis | Durvalumab
Institut Cancerologie de l'Ouest
Esteve

Recruiting

OP2C : Prialt® Observatory in Clinical Practice (OP2C)

Refractory Pain

France
PT. Prodia Stem Cell Indonesia

Recruiting

Stem Cell and Conditioned Medium for Cerebral Palsy

Cerebral Palsy

Indonesia
Duke University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

Heart Failure | Pain | Pneumonia | Hypertension | Edema | Hemophilia | Insomnia | Pulmonary Arterial Hypertension | Coagulation Disorder | Asthma in Children | Down Syndrome | Attention Deficit Hyperactivity Disorder | Bronchopulmonary Dysplasia | Hypokalemia | Hyperphosphatemia | Primary Hyperaldosteronism | Adrenal Insufficiency and other conditions

United States, Canada
Daiichi Sankyo, Inc.
Children's Oncology Group; Innovative Therapies For Children with Cancer Consortium

Recruiting

Safety and Efficacy of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Blood

Acute Myeloid Leukemia

United States, Spain, France, Israel, Denmark, Canada, Belgium, Italy, Netherlands, Sweden, United Kingdom
University of Manitoba

Recruiting

Spinal Anesthesia For Enhanced Recovery After Liver Surgery (SAFER-L)

Pain, Postoperative | Liver Neoplasms | Hepatectomy

Canada
Augusta University

Recruiting

Comparison of Intrathecal Versus Epidural Fentanyl on Fetal Bradycardia in Labor Combined Spinal Epidural Analgesia

Labor Pain | Obstetric Pain

United States
University of Chicago
Incyte Corporation

Recruiting

Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | ALL, Childhood | ALL

United States
Sclnow Biotechnology Co., Ltd.

Not yet recruiting

Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-SA) for Patients With Spinocerebellar Ataxia

Spinocerebellar Ataxia Type 3 | Spinocerebellar Ataxia Type 1 | Spinocerebellar Ataxia Type 2 | Spinocerebellar Ataxia Type 6
Northwestern University

Recruiting

Cognitive Effects of Androgen Receptor Directed Therapies for Advanced Prostate Cancer

Metastatic Prostate Carcinoma | Recurrent Prostate Carcinoma | Stage IV Prostate Cancer | Hormone-Refractory Prostate Cancer | Castration-Resistant Prostatic Cancer

United States
Navy General Hospital, Beijing

Recruiting

Therapeutic Effects of R-IDARAM and Intrathecal Immunochemotherapy on Elderly Patients With PCNSL

Primary Central Nervous System Lymphoma

China
UMC Utrecht
National University Hospital, Singapore; Berry Consultants; University of Pittsburgh... and other collaborators

Recruiting

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia (REMAP-CAP)

Community-acquired Pneumonia, Influenza, COVID-19

United Kingdom, United States, Canada, Australia, Netherlands, Croatia, Germany, Belgium, New Zealand, Ireland, Spain, Japan, Hungary, Colombia, India, Nepal, Pakistan, Portugal, Romania, Saudi Arabia
Navy General Hospital, Beijing

Recruiting

Treatment of PCNSL With R-IDARAM and Intrathecal Immunochemotherapy

Primary Central Nervous System Lymphoma

China
Sun Yat-sen University

Recruiting

Modified BFM-95 Regimen as First-Line Chemotherapy in Adults With T- Lymphoblastic Lymphoma

Lymphoma, Lymphoblastic

China
The Korean Society of Pediatric Hematology Oncology

Recruiting

Treatment of Newly Diagnosed High Risk Acute Lymphoblastic Leukemia in Children

Child | Acute Lymphoblastic Leukemia

Korea, Republic of
Joanne Kurtzberg, MD
The Marcus Foundation

Recruiting

UCB Transplant of Inherited Metabolic Diseases With Administration of Intrathecal UCB Derived Oligodendrocyte-Like Cells (DUOC-01)

Mucopolysaccharidosis II | Brain Diseases, Metabolic, Inborn | Adrenoleukodystrophy | Batten Disease | Leukodystrophy, Metachromatic | Leukodystrophy, Globoid Cell | Alpha-Mannosidosis | Tay-Sachs Disease | Pelizaeus-Merzbacher Disease | Sandhoff Disease | Neimann Pick Disease | Sanfilippo Mucopolysaccharidoses

United States
National Institute of Dental and Craniofacial Research...
National Institute of Neurological Disorders and Stroke (NINDS); Sorrento Therapeutics...

Recruiting

Resiniferatoxin to Treat Severe Pain Associated With Advanced Cancer

Palliative Care | Intractable Pain

United States
Shire
Takeda Development Center Americas, Inc.

Active, not recruiting

A Study of Intrathecal SHP611 in Children With Metachromatic Leukodystrophy (EMBOLDEN)

Metachromatic Leukodystrophy (MLD)

United States, Canada, Belgium, Israel, Netherlands, United Kingdom, Germany, Spain, Japan, Brazil, Argentina, France, Greece, Italy
Vinmec Research Institute of Stem Cell and Gene...

Completed

Stem Cell Infusion in the Treatment of Patients With Neurological Complications After Ischemic Stroke

Ischemic Stroke

Vietnam
St. Jude Children's Research Hospital

Active, not recruiting

A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia

Acute Myeloid Leukemia | Myelodysplastic Syndromes

United States
Cairo University

Completed

Analgesic Efficacy of Sequential Rapid Versus Slow Intrathecal Injection Of Dexmedetomidine Followed by of Hyperbaric Bupivacaine in Inguinal Hernia Repair Surgery

Postoperative Pain

Egypt
Marmara University

Completed

Analgesic Effects of Intrathecal Morphine and Bilateral Erector Spina Plane Block in Elective Cesarean Section

Postoperative Pain | Opioid Use

Turkey
University of Miami

Suspended

Intrathecal Morphine vs. Intrathecal Morphine and Regional Anesthesia After Cesarean Section.

Post-operative Pain

United States
Ondokuz Mayıs University

Completed

The Effect of Music Intervention on Anxiety, Fear, and Pain in Pediatric Patients Receiving Intrathecal Chemotherapy

Nurse's Role

Turkey
Ondokuz Mayıs University

Completed

The Contribution of Intrathecal Morphine Administration to Postoperative Patient Satisfaction During Cesarean Delivery (ITM)

Cesarean Section | Intrathecal Morphine | Quality of Recovery 40

Turkey
St. Jude Children's Research Hospital
AbbVie

Active, not recruiting

Trial Treating Relapsed Acute Lymphoblastic Leukemia With Venetoclax and Navitoclax

Refractory Acute Lymphoblastic Leukemia | Relapsed Acute Lymphoblastic Leukemia

United States
Beth Israel Deaconess Medical Center

Completed

Intrathecal Morphine for Cesarean Delivery

Postoperative Pain

United States
Al-Azhar University

Completed

Dexmedetomidine vs Fentanyl in Controlling Labor Pain

Labor Pain

Egypt
Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Completed

The Effect of Analgesia Methods Applied in Gynecological Cancer Surgeries on Postoperative Analgesia

Regional Anesthesia Morbidity | Gynecological Cancer Surgery

Turkey
University of Oxford
UCB Pharma; Oxford University Hospitals NHS Trust; Oxford Health NHS Foundation... and other collaborators

Completed

An Investigation of Levetiracetam in Alzheimer's Disease (ILiAD)

Epilepsy | Alzheimer Disease

United Kingdom
Tanta University

Completed

Ilioinguinal Iliohypogastric Nerve Block as Adjunct to Spinal Anesthesia for Cesarean Section

Cesarean Section | Post Operative Pain

Egypt
Amgen
Innovative Therapies For Children with Cancer Consortium; Therapeutic Advances...

Active, not recruiting

Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia (ALL)

Spain, United Kingdom, United States, Korea, Republic of, Czechia, France, Russian Federation, Saudi Arabia, Thailand, Canada, Italy, Singapore, Turkey, Taiwan, Portugal, Poland, Romania, Brazil, Australia, Greece, Argentina, Mexico, Austr... and more
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Nab-paclitaxel and Alpelisib for the Treatment of Anthracycline Refractory Triple Negative Breast Cancer With PIK3CA or PTEN Alterations

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
Tisch Multiple Sclerosis Research Center of New...

Completed

Intrathecal Administration of Autologous Mesenchymal Stem Cell-derived Neural Progenitors (MSC-NP) in Progressive Multiple Sclerosis

Multiple Sclerosis

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI); Varian Medical Systems

Suspended

Split Course Adaptive Radiation Therapy With Pembrolizumab With/Without Chemotherapy for Treating Stage IV Lung Cancer

Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer AJCC v8 | Stage III Lung Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease

Metastatic Lung Non-Small Cell Carcinoma | Metastatic Melanoma | Stage IV Lung Cancer AJCC v8 | Metastatic Uveal Melanoma | Acral Lentiginous Melanoma | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Leptomeningeal Neoplasm | Metastatic Mucosal Melanoma | Central Nervous System Melanoma | Melanocytoma

United States
Hoffmann-La Roche

Active, not recruiting

A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumors

Neuroblastoma | Solid Tumors | Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL)

France, United States, Spain, Canada, United Kingdom, Netherlands
Marmara University

Completed

Comparing Intrathecal Morphine With Erector Spina Plane Block in Open Gastrectomy Surgery

Opioid Use | Post Operative Pain | Pain Assessment Scales

Turkey
Mayo Clinic

Completed

Intrathecal Opioids for Colorectal Resection

Pain, Postoperative | Colorectal Surgery | Analgesic, Opioid

United States
Hospital JP Garrahan
Hospital San Juan de Dios, Santiago

Active, not recruiting

Treatment Protocol for Non-Metastatic Unilateral Retinoblastoma (RbGALOP2)

Unilateral Retinoblastoma

Argentina
National Cancer Institute, Egypt

Completed

Intrathecal Dexmedetomidine vs Midazolame

Postoperative Pain

Egypt
Samsung Medical Center
Korea Institute of Science and Technology

Completed

Effects of Dexmedetomidine/Lidocaine/Intrathecal Morphine on Cancer Metastasis Biomarker After Colorectal Surgery

Inflammation | Colorectal Cancer | Anesthesia | Cancer Metastatic

Korea, Republic of
Hoffmann-La Roche

Completed

A Study to Evaluate the Efficacy and Safety of Intrathecally Administered RO7234292 (RG6042) in Participants With Manifest Huntington's Disease

Huntingtons Disease

United States, United Kingdom, Australia, Canada, Japan, Poland, Netherlands, Germany, Russian Federation, France, Spain, Argentina, New Zealand, Austria, Denmark, Italy, Switzerland, Chile
Zagazig University

Active, not recruiting

Intrathecal Injection of Pethidine Plus Dexamethasone Versus Bupivacaine Alone

Postoperative Pain

Egypt
Masonic Cancer Center, University of Minnesota

Active, not recruiting

Neurotoxicity Prophylaxis With Intrathecal Dexamethasone and Simvastatin Post Axi-Cel

Lymphoma

United States
Medical University of South Carolina

Completed

Comparison of 0.1 and 0.05mg Intrathecal Morphine for Post-cesarean Analgesia.

Cesarean Section

United States
Novartis Pharmaceuticals

Active, not recruiting

Efficacy and Safety of Intrathecal OAV101 (AVXS-101) in Pediatric Patients With Type 2 Spinal Muscular Atrophy (SMA) (STEER)

Type 2 Spinal Muscular Atrophy

United States, China, Saudi Arabia, Thailand, Singapore, Brazil, Malaysia, Taiwan, Colombia, Mexico, Denmark, Egypt, India, South Africa, Vietnam
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Ultrasound-assisted vs Landmark Based Intrathecal Administration of Nusinersen

Muscular Atrophy, Spinal | Ultrasound

Italy
Ciusss de L'Est de l'Île de Montréal

Withdrawn

Improving ObsQoR-11 With Continuous Wound Infusion Versus Intrathecal Morphine After Elective Cesarean Delivery (CIVIMEC)

Postoperative Pain | Cesarean Section | Anesthesia | Quality of Recovery

Canada

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