The Effect of Analgesia Methods Applied in Gynecological Cancer Surgeries on Postoperative Analgesia

April 24, 2024 updated by: Duygu Akyol, Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Four-quadrant Transversus Abdominis Plane Block Versus Intrathecal Morphine in Gynecological Cancer Surgeries: a Single-center Retrospective Study.

The aim of this study is to compare the effectiveness of intrathecal morphine and four-quadrant transversus abdominis plane block applied for postoperative analgesia in gynecological cancer surgeries.

The key question(s) it aims to answer are:

[Is intrathecal morphine more effective in postoperative analgesia?] Patients who underwent gynecological cancer surgery were examined retrospectively. The investigators evaluated the effect of intrathecal morphine and four-quadrant transversus abdominis plane block applied for postoperative analgesia on pain scores and postoperative opioid use.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Our study was designed retrospectively. The investigators evaluated analgesia methods in patients who underwent laparoscopic or open surgery due to gynecological cancer between June 2023 and December 2023. The investigators evaluated the effect of intrathecal morphine and four-quadrant transversus abdominis plane block on postoperative analgesia and opioid use.

Group 1: Intrathecal morphine administered group Group 2: Four quadrant transversus abdominis plane block applied group

Study Type

Observational

Enrollment (Actual)

71

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey
    • Basaksehir
      • Istanbul, Basaksehir, Turkey
        • Başakşehir Çam and Sakura City Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Non-Probability Sample

Study Population

Between June 1, 2023 and December 1, 2023, 71 patients over the age of 18 who underwent surgery for ASA II and III gynecological cancer, to whom we applied intrathecal morphine or four-quadrant transversus abdominis plane block (TAPB) from peripheral nerve blocks for postoperative analgesia, were included in the study.

Description

Inclusion Criteria:

  • 18 years

    • Patients who have undergone gynecological cancer surgery

Exclusion Criteria:

  • <18 years
  • Those with missing data

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Group 1: Intrathecal morphine administered group
Procedure: Intrathecal morphine administered group, Four quadrant transversus abdominis plane block applied group
Intrathecal morphine administered group and Four quadrant transversus abdominis plane block applied group
Other Names:
  • Group 1: Intrathecal morphine administered group
  • Group 2: Four quadrant transversus abdominis plane block applied group
Group 2: Four quadrant transversus abdominis plane block applied group
Procedure: Intrathecal morphine administered group, Four quadrant transversus abdominis plane block applied group
Intrathecal morphine administered group and Four quadrant transversus abdominis plane block applied group
Other Names:
  • Group 1: Intrathecal morphine administered group
  • Group 2: Four quadrant transversus abdominis plane block applied group

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
postoperative numerical rating scale
Time Frame: 24 hours postoperatively
Our primary aim was to evaluate numerical rating scale at 24 hours postoperatively. numerical rating scale(NRS) was used to assess postoperative pain. NRS values were recorded For example, 0-10 where 0 is no pain and 10 is the worst pain imaginable.
24 hours postoperatively

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
postoperative opioid use
Time Frame: 24 hours postoperatively
Our secondary aim was to evaluate opioid demand and consumption amounts in the postoperative 24 hours.
24 hours postoperatively

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Investigators

  • Principal Investigator: Duygu Akyol, Başakşehir Çam & Sakura City Hospital

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 1, 2023

Primary Completion (Actual)

December 1, 2023

Study Completion (Actual)

March 1, 2024

Study Registration Dates

First Submitted

April 20, 2024

First Submitted That Met QC Criteria

April 20, 2024

First Posted (Actual)

April 24, 2024

Study Record Updates

Last Update Posted (Actual)

April 26, 2024

Last Update Submitted That Met QC Criteria

April 24, 2024

Last Verified

April 1, 2024

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2024-60

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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