Search clinical trials for: open label

Total 9440 results

Lady Hardinge Medical College

Recruiting

Modified Atkins Diet Versus Topiramate In Children With Epileptic Spasms Refractory To Hormonal Treatment: A Randomized Open-Label Study (TOPAMAD)

Epileptic Spasms, Failed Hormonal Therapy

India
University of California, Los Angeles
PoloMar Health LLC

Not yet recruiting

An Open-Label, Single-Arm Clinical Trial Evaluating the Safety and Efficacy of Amisulpride in Treating Patients With Schizophrenia and Schizoaffective Disorder Who Have Treatment-Resistant Positive Symptoms (AmisulprideTRS)

Schizophrenia, Treatment-Resistant
Forma Therapeutics, Inc.
Novo Nordisk A/S

Recruiting

A Phase 2 Open-label Study to Evaluate the Activity of Etavopivat on Transcranial Doppler Velocities in Pediatric Patients With Sickle Cell Disease Who Are at Increased Risk for Primary Stroke

Sickle Cell Disease

Nigeria, India, Oman
Rhode Island Hospital

Not yet recruiting

Optimizing Open Label Placebo Rationales

Chronic Pain
Shanghai 6th People's Hospital

Recruiting

A Single-arm, Open-label, Single-center Prospective Study of Fruquintinib Combined With Envafolimab in the Treatment of Advanced or Unresectable Locally Advanced Bone and Soft Tissue Sarcoma

Advanced or Unresectable Locally Advanced Bone and Soft Tissue Sarcoma

China
Tianjin Medical University Cancer Institute and...

Recruiting

Continuation of Serplulimab Plus Chemotherapy After First Progression in Advanced Gastric or Gastro-oesophageal Junction Adenocarcinoma: an Open-label, Randomised Phase II Trial

Gastric Cancer (GC) Gastroesophageal Junction Cancer (GEJ)

China
Novartis Pharmaceuticals

Recruiting

An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC. (PSMA-DC)

Oligometastatic Prostate Cancer (OMPC)

Japan, Singapore, Canada, Israel, Switzerland, Australia, United States
Chulalongkorn University
HIV-NAT, Thai Red Cross - AIDS Research Centre; Chula Clinical Research Center...

Recruiting

Immunogenicity and Safety of Comvigen (Bivalent) Vaccine

Safety of a Single Dose of COMVIGEN Vaccine | Reactogenicity of a Single Dose of COMVIGEN Vaccine | Immunogenicity of a Single Dose of COMVIGEN Vaccine | Safety of a Single Dose of BIVALENT Pfizer/BNT Vaccine | Reactogenicity of a Single Dose of BIVALENT Pfizer/BNT Vaccine | Immunogenicity...

Thailand
University of Milano Bicocca

Not yet recruiting

Phase 2, Open-label, Single-arm Study on the Use of Metformin as Adjunctive Therapy in High-grade Glioma

Malignancies | Glioblastoma, IDH-wildtype | Metformin

Italy
Flare Therapeutics Inc.

Recruiting

A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma

Advanced Solid Tumors Cancer | Advanced Urothelial Carcinoma | Open Label | Oral Drug Administration

United States
AstraZeneca

Recruiting

Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY) (DAISY)

Systemic Sclerosis | Scleroderma

United States, Italy, Mexico, Hungary, Belgium, Spain, Japan, Poland, Germany, China, India, Korea, Republic of, Vietnam, France, Austria, Israel, Canada, Turkey, Netherlands, United Kingdom, South Africa, Romania
Mayo Clinic

Recruiting

A Study of FRaDCs for Ovarian Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Ovarian High Grade Serous Adenocarcinoma | Fallopian Tube Carcinosarcoma | Primary Peritoneal Carcinosarcoma | Recurrent Fallopian Tube Clear Cell Adenocarcinoma | Recurrent Fallopian... and other conditions

United States
University of Derby
University of Exeter; University Hospitals of Derby and Burton NHS Foundation... and other collaborators

Not yet recruiting

An Open-label, Clinical Feasibility Study of the Efficacy of Remdesivir for Long-COVID. (ERASE-LC)

COVID-19 | SARS-CoV-2 Infection

United Kingdom
National Institute of Allergy and Infectious Diseases...

Recruiting

Study of the Plasmodium Vivax Transmission-blocking Vaccine Pvs230D1-EPA/Matrix-M to Assess Safety, Immunogenicity, and Transmission-blocking Activity in Healthy Malaria-naive Adults

Malaria

United States
Servier Affaires Médicales

Recruiting

An Open-label Phase 3b Study of Ivosidenib in Combination With Azacitidine in Adult Patients Newly Diagnosed With IDH1m Acute Myeloid Leukemia (AML) Ineligible for Intensive Induction Chemotherapy.

Acute Myeloid Leukemia (AML)

Netherlands, Italy, Austria, France
National Taiwan University Hospital

Not yet recruiting

Efficacy of Lenalidomide Maintenance in Primary Central Nervous System Lymphoma and Primary Vitreoretinal Lymphoma: a Phase II, Open-label, Single-arm Study

Primary Central Nervous System Lymphoma and Primary Vitreoretinal Lymphoma
Novartis Pharmaceuticals

Recruiting

An Open Label Extension (OLE) Study to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230) (OLE)

Hyperlipoproteinemia (a)

Germany
Erasmus Medical Center

Recruiting

TEIPP Immunotherapy in Patients With NSCLC (TEIPP)

Non Small Cell Lung Cancer

Netherlands
Medical University of South Carolina
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institutes...

Recruiting

rTMS in Older Adults With MCI and AUD

Transcranial Magnetic Stimulation | Mild Cognitive Impairment | Alcohol Use Disorder

United States
Inhibrx, Inc.

Not yet recruiting

Open Label Extension Study of INBRX-101 in Adults With AATD Emphysema (ELEVAATE OLE)

Emphysema | Alpha 1-Antitrypsin Deficiency
Centre Francois Baclesse
National Cancer Institute, France

Not yet recruiting

Long-term Cognitive and Functional Impact of Proton-therapy or Modern Fractionated Radiotherapy in Cavernous Sinus Meningioma: An Open-label Randomized 1:1 Phase III Study (COG-PROTON-01)

Cognitive Impairment | Cavernous Sinus Meningioma | Proton-therapy | Photon Radiotherapy

France
Advanced Integrative Medical Science Institute

Not yet recruiting

Open-Label Dose-Ranging Study of Oral SM-001 in Healthy Adults

Major Depression | Post Traumatic Stress Disorder

United States
Yonsei University

Not yet recruiting

An Open Label, Single-arm, Multicenter Phase Ib/II Study to Evaluate the Safety and Efficacy of T-Dxd in Combination With Ramucirumab as a 2nd Line in Patients With HER2 Low Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma

Gastric Cancer | Gastroesophageal Junction (GEJ) Cancer
Shanghai Pulmonary Hospital, Shanghai, China

Not yet recruiting

Neoadjuvant Therapy With Toripalimab and JS004 Combined With Platinum-based Doublet Chemotherapy for Resectable or Potentially Resectable Stage III Non-small Cell Lung Cancer: A Randomised Controlled, Open-label, Phase 2 Trial

Stage III Non-small Cell Lung Cancer
Fudan University

Not yet recruiting

A Randomized, Controlled, Open-label Clinical Trial of Adjuvant Intensive Therapy for HR+/ HER2-SNF4 Early Breast Cancer

HR+/HER2-breast Cancer
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

An Open-label Phase 3 Study of Lutetium (177Lu) Oxodotreotide Injection in Subjects With Advanced Gastrointestinal Pancreatic Neuroendocrine Tumors.

Advanced Gastroenteropancreatic Neuroendocrine Tumor

China
River 2 Renal Corp.

Recruiting

Study to Evaluate R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients With Hepatorenal Syndrome

Acute Kidney Injury | Hepatorenal Syndrome

United States
Memorial Sloan Kettering Cancer Center
Sanofi

Recruiting

Open-Label, Phase II Trial of Isatuximab for Patients With Refractory Immune Cytopenias After Allogeneic Hematopoietic Cell Transplantation

Blood Cancer | Refractory Immune Cytopenias

United States
Akeso

Recruiting

A Phase Ia/Ib Open Label，Clinical Study Evaluating the Safety, Tolerability and Preliminary Efficacy of AK127 in Combination With AK104 in Patients With Advanced Malignant Tumors

Advanced Malignant Tumors

China
Ichnos Sciences SA

Recruiting

Study of ISB 2001 in Relapsed/Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma

United States, Australia
Shantou University Medical College
Guangdong ProCapZoom Biosciences Co., Ltd.

Not yet recruiting

Single-arm, Open-label Clinical Study of SZ011 in the Treatment of Ovarian Epithelial Carcinoma

Ovarian Epithelial Carcinoma
Sinovac Biotech Co., Ltd

Recruiting

A Multi-center, Open-labelled, Randomized, Controlled, Extended Phase Ⅲ Clinical Trial of sIPV Vaccine

Poliomyelitis | Polio

Pakistan, Bangladesh
PRG Science & Technology Co., Ltd.

Not yet recruiting

Phase 2, Open-Label Study to Evaluate the Safety and Tolerability of Progerinin in Werner Syndrome

Werner Syndrome
Servier Bio-Innovation LLC
Institut de Recherches Internationales Servier

Recruiting

A Phase 1, Open-Label Study to Evaluate the Effect of a Low-Fat Meal and Multiple Doses of Ciprofloxacin on the Pharmacokinetics of Vorasidenib in Healthy Subjects

Healthy Subjects

United States
Shantou University Medical College
Guangdong ProCapZoom Biosciences Co., Ltd.

Not yet recruiting

Single-arm, Open-label Clinical Study of SZ003 in the Treatment of Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma
Central South University

Recruiting

Using 18F-FPEB PET to Identify mGLUR5 Availability in Affective Disorders

Bipolar Disorder | Major Depressive Disorder

China
Pathalys Pharma
Launch Therapeutics

Recruiting

Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-2 (PATH-2)

Secondary Hyperparathyroidism | End Stage Kidney Disease

United States, Bulgaria, Portugal, Spain, Serbia, Poland
Pfizer

Recruiting

A Study to Learn About the Effectiveness of Cancer Medicines in Patients With Metastatic Non-small Cell Lung Cancer in Norway. (DELINOR)

Non-Small Cell Lung Cancer

Norway
Pathalys Pharma
Launch Therapeutics

Recruiting

Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-1 (PATH-1)

Secondary Hyperparathyroidism | End-stage Kidney Disease (ESKD)

United States, Bulgaria, Spain, Portugal, Poland, Serbia
MicroPort NeuroTech Co., Ltd.

Recruiting

PROSPECTIVE, MULTI-CENTER, OPEN-LABEL, SINGLE-ARM REGISTRATION TRIAL OF THE TUBRIDGE FOR THE TREATMENT OF WIDE-NECKED SMALL AND MEDIUM-SIZED INTRACRANIAL ANEURYSMS

Cardiovascular Diseases | Brain Diseases | Aneurysm | Intracranial Aneurysm

China
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Recruiting

Baricitinib, Methotrexate as Monotherapy or Combination in the Treatment of Rheumatoid Arthritis - an Open Label Randomized Clinical Trial

Rheumatoid Arthritis

Bangladesh
APR Applied Pharma Research s.a.

Recruiting

Open-label, Randomized, 2-way Crossover, Monocentric, Controlled Study to Evaluate the Effect on Daily PHE Fluctuation of PKU GOLIKE Versus SoC in Patients With PKU.

Phenylketonurias

Italy
Magnus Medical

Recruiting

Open Label Optimization Study (OLO)

Major Depressive Disorder

United States
University Hospital, Basel, Switzerland

Recruiting

Boosting Open-Label Placebo Effects in Acute Induced Pain in Healthy Adults (BOLPAP)

Acute Pain

Switzerland
Sinocare
Integrated Medical Development

Recruiting

Accuracy and Precision of the True Vie I3 Continuous Glucose Monitoring System: an Open Label, Multi-Center Trial

Diabetes Mellitus

United States
Dilla University

Not yet recruiting

Participant Centered Active Surveillance for Adverse Event Following Measles Immunization in Gedeo Zone, Ethiopia, 2022. A Multi-center Open-label Randomized Control Trial

Measles

Ethiopia
Novartis Pharmaceuticals

Recruiting

An Open-label, Study to Assess Safety, Efficacy and Cellular Kinetics of YTB323 in Severe, Refractory Systemic Lupus Erythematosus

Systemic Lupus Erythematosus | Lupus Nephritis

Spain, Switzerland, Germany, Australia, France, United States
Quoin Pharmaceuticals

Recruiting

Open Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton Syndrome

Netherton Syndrome

United States
Overseas Pharmaceuticals, Ltd.
Beijing Capton Pharmaceutical Technology Development Co., LTD

Not yet recruiting

An Open Label, Balanced, Randomized, Two-Treatment, Two-Period, Two-Sequence, Two-way Crossover, Oralcomparative Pharmacokinetic（PK）Study of Lacosamide Extended-Release Tablets , Adult, Human Subjects Under Fasting Conditions.

Epilepsy

China
Sanofi

Recruiting

Open Label, Long-term Study Evaluating Safety and Efficacy of Subcutaneous Amlitelimab in Participants Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis (ATLANTIS)

Dermatitis Atopic

Italy, United Kingdom, Argentina, France, Chile, Czechia, Germany, Japan, Spain, China, Netherlands, Brazil, Canada, Denmark, Korea, Republic of, South Africa, Taiwan, Poland, India, Mexico

Search clinical trials for: open label

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