Search clinical trials for: maximum tolerable dose

Total 21233 results

Hamamatsu University
Maruyama Memorial General Hospital; Seirei Hamamatsu General Hospital; Iwata... and other collaborators

Terminated

Study of the Relationship Between rHuEPO Dose, Serum ADPN, and Mortality in Patients Beginning HD

Renal Dialysis
University Heart Center Freiburg - Bad Krozingen

Unknown

Effect of Clopidogrel Loading and Risk of PCI (EXCELSIOR)

Coronary Artery Disease | Drug Resistance

Germany
Casa Sollievo della Sofferenza IRCCS

Completed

High Versus Standard Dose of Proton Pump Inhibitors (PPIs) in Peptic Ulcer Bleeding

Upper Gastrointestinal Bleeding | Peptic Ulcers

Italy
Groupe Francophone des Myelodysplasies

Completed

Thalidomide at Low Dose for the Treatment of Patient With Myelodysplastic Syndromes - THAL-SMD-200

Myelodysplastic Syndromes

France
ProEthic Pharmaceuticals

Completed

An Efficacy Study of a Single Dose Treatment of PRO-513 for Subjects Suffering a Migraine Attack

Migraine | Photophobia | Phonophobia

United States
Pfizer

Terminated

Placebo Controlled Dose-Response Study Of PD-217,014 In The Treatment Of Postherpetic Neuralgia

Pain

Australia, Spain, Canada, Czech Republic, Netherlands, United Kingdom
Samuel Lunenfeld Research Institute, Mount Sinai...

Completed

Ideal Dose of Phenylephrine to Treat Low Blood Pressure During Cesarean Section

Nausea | Hypotension

Canada
Manhattan Pharmaceuticals

Unknown

Phase 2a Obesity Study of Oral Doses of Oleoyl-Estrone (MP-101)

Obesity

United States, Switzerland
AstraZeneca

Completed

Dose Ranging, Safety and Tolerability of TOPROL-XL® Extended-Release Tablets in Hypertensive Pediatric Subjects (307A)

Hypertension

United States, Dominican Republic
Cure Therapeutics

Unknown

Phase II Dose-Ranging Study of OrthoDerm Patch for Patients With Tennis Elbow

Tendonitis

Poland
Novartis
Novartis Vaccines

Completed

Safety and Immunogenicity of Two Doses, Administered Three Weeks Apart, of Two(Surface Antigen Adjuvanted With MF59C.1) Influenza Vaccines in Non-Elderly Adult and Elderly Subjects

Pandemic Influenza Disease

Italy
Groupe Francophone des Myelodysplasies

Unknown

Bortezomib and Low Dose Cytarabine in the Treatment of High-Risk Myelodysplastic Syndromes

Myelodysplastic Syndromes

France
National Center for Complementary and Integrative...
National Institute of General Medical Sciences (NIGMS); Office of Dietary Supplements...

Completed

Single-Dose Study of Black Cohosh and Red Clover

Menopause
McGill University
McGill University Health Centre/Research Institute of the McGill University...

Unknown

Study Combining Zevalin With High-Dose Chemotherapy Prior to Autologous StemCell Transplant in Patients With Relapsed, Refractory, or Transformed Non-Hodgkin's Lymphoma (Zevalin)

Non-Hodgkin's Lymphoma

Canada
Azienda Ospedaliera San Giovanni Battista
Hoffmann-La Roche; University of Turin, Italy; Gruppo Italiano Trapianto di Midollo... and other collaborators

Unknown

Comparison of High-Dose Chemotherapy + Rituximab and CHOP + Rituximab in High-Risk Follicular Lymphoma

Follicular Lymphoma

Italy
Heidelberg University
Dietmar Hopp Stiftung; Prof. Wolfgang Stremmel

Completed

Dose Finding Study for Retarded Phosphatidylcholine in Pancolitis

Ulcerative Colitis

Germany
Semmelweis University

Unknown

Autoimmunity in Retinitis Pigmentosa

Retinitis Pigmentosa

Hungary
Università Politecnica delle Marche

Unknown

High Dose Intravenous N-Acetylcysteine Versus Iloprost for Early, Rapidly Progressive Diffuse Systemic Sclerosis

Scleroderma, Diffuse

Italy
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Sirolimus and Cyclosporine in Kidney Transplant Recipients

Renal Transplantation
Eli Lilly and Company

Completed

Efficacy of High Dose Olanzapine for the Treatment of Schizophrenia and Schizoaffective Disorder

Schizophrenia | Schizoaffective Disorder

United States
Eli Lilly and Company

Completed

Study Comparing Short Infusion Vs. Fixed Dose of Cisplatin + Gemcitabine in Non Small Cell Lung Cancer.

Non-Small-Cell Lung Carcinoma

Argentina, Brazil, Chile, Mexico
Eli Lilly and Company

Completed

A Comparison of Tolerability and Efficacy of Different Doses of Duloxetine for the Treatment of Major Depressive Disorder

Depressive Disorder

United States
Eli Lilly and Company
Aventis Pharmaceuticals

Completed

A Randomized Study Evaluating the Feasibility and Activity of Three Different Combination With Gemcitabine as First Line Therapy for Non Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

Italy
BZL Biologics

Completed

Phase II Trial of Monoclonal Antibody (J591) in Combination With Low-Dose Subcutaneous Interleukin-2

Prostatic Neoplasms

United States
Japan Clinical Oncology Group
Ministry of Health, Labour and Welfare, Japan

Terminated

Study of Standard CHOP Versus Biweekly CHOP in Aggressive Non-Hodgkin's Lymphoma (JCOG9809)

Non-Hodgkin's Lymphoma

Japan
National Cancer Center, Korea

Completed

Early Low Dose Steroid Therapy of Acute Respiratory Distress Syndrome

Postoperative Complications | Acute Respiratory Distress Syndrome | Acute Lung Injury

Korea, Republic of
Eyetech Pharmaceuticals
Pfizer

Terminated

A Clinical Trial to Explore the Safety and Efficacy of Three Different Doses of Pegaptanib Sodium in Patients With Wet Age-Related Macular Degeneration (AMD)

Macular Degeneration

United States
Istituto Clinico Humanitas
Lega Italiana per la Lotta contro i Tumori

Terminated

The DANTE Trial. A Randomized Study on Lung Cancer Screening With Low-Dose Spiral Computed Tomography

Lung Cancer

Italy
National Institute of Arthritis and Musculoskeletal...

Terminated

Low-Dose Hormone Replacement Therapy and Alendronate for Osteoporosis

Osteoporosis | Osteopenia

United States
Nordic Myeloma Study Group
Nordic Cancer Union

Completed

Pamidronate Prophylaxis in Multiple Myeloma 30 mg/Month Versus 90 mg/Month

Multiple Myeloma

Denmark, Norway, Sweden
Epicentre
University of Oslo; Norwegian Institute of Public Health; Medecins Sans Frontieres...

Completed

Fractional Dose Tetravalent A, C, Y, W135 Meningococcal Polysaccharide Vaccine

Infections, Meningococcal | Meningitis, Meningococcic

Norway, Uganda
Pfizer

Completed

Safety, Toleration and Pharmacokinetics of Single Intravenous Doses of Peptide YY in Overweight Adults

Obesity

United States
Protalix

Completed

Phase I Single Dose-Escalation Safety Study of Human Glucocerebrosidase (prGCD)

Gaucher Disease
University of Turku
Hoffmann-La Roche

Unknown

Safety and Efficacy Study of Intravenous Loading Dose of Ibandronate in Breast Cancer Patients

Breast Cancer

Finland
Steno Diabetes Center Copenhagen

Completed

Maximal Dose of Angiotensin Converting Enzyme (ACE) Inhibitor for Treatment of Diabetic Kidney Disease

Diabetic Nephropathy | Diabetes Mellitus, Type I

Denmark
Denver Health and Hospital Authority
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Completed

Effects of Therapeutic Doses of Acetaminophen in Moderate Drinkers

Moderate Alcohol Consumption (1-3 Drinks Per Day)
Novalar Pharmaceuticals, Inc.

Completed

Study of NV-101 for Efficacy, Pharmacodynamics, and Safety in Dental Patients Undergoing Maxillary Procedures

Anesthesia, Dental

United States
Assistance Publique - Hôpitaux de Paris
Danone Institute International

Terminated

Effects of Peptides Derived From Fermented Milk on Blood Pressure Regulation System in Healthy Volunteers.

Healthy

France
AGO Study Group

Completed

Randomized, Multicenter, 2-Dose Level. Open-Label, Phase IIa Study With the Intraperitoneally Infused Trifunctional Bispecific Antibody Removab(TM) (Anti-EpCAM x Anti-CD3) to Select the Better Dose Level in Platinum Refractory Epithelial Ovarian Cancer Patients

Fallopian Tube Neoplasms | Peritoneal Neoplasms | Ovarian Cancer

Germany
Kos Pharmaceuticals

Completed

The Dose Response of Niacin ER/Lovastatin on Peak Walking Time (PWT) in Patients With Intermittent Claudication - TROPIC

Intermittent Claudication | Peripheral Vascular Disease

United States
Novacea

Unknown

Study of High-Dose Pulse Administration DN-101 (Calcitriol) in Patients With Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndrome

United States
Kos Pharmaceuticals

Completed

Safety & Efficacy of a Combination Niacin ER/Simvastatin in Patients With Dyslipidemia: A Dose-Ranging Study - SEACOAST

Hypercholesterolemia
Assistance Publique - Hôpitaux de Paris

Terminated

Analgesic Effect in Children of Low-Dose Ketamine for Mucositis Treated by Patient-Controlled Analgesia With Morphine

Cancer | Mucositis

France
Hospital Clinic of Barcelona

Completed

Study Comparing Reducing the Dose of Stavudine Versus Switching to Tenofovir in HIV-Infected Patients Receiving Antiretroviral Therapy

HIV Infections | Lipoatrophy
Chang Gung Memorial Hospital

Completed

Long-Term Lead Chelation Therapy and Progressive Renal Insufficiency

Urologic Disease

China
Angiogenix

Unknown

Efficacy Study of Oral L-Citrulline in Patients Taking Simvastatin With Peripheral Arterial Disease

Peripheral Arterial Disease | Intermittent Claudication

Russian Federation
Washington University School of Medicine

Terminated

Single Dose Thymoglobulin for Induction in Adult Renal Allograft Recipients

Kidney Transplantation

United States
University Health Network, Toronto

Unknown

Proper Dosage of Ketamine in Intravenous Regional Anesthesia

Pain.

Canada
Odense University Hospital

Unknown

Insulin NovoRapid Versus Actrapid in Treatment of Type 1 Diabetic Patients During Daily Adjustment of Insulin Dose

Type 1 Diabetes Mellitus

Denmark
GlaxoSmithKline

Completed

Comparison of Adjuvanted Hepatitis B Vaccine to Double Dose of Engerix™-B in Pre- /Haemodialysis Patients Aged ≥15 Years

Hepatitis B

Czech Republic, Malaysia, Spain

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