Search clinical trials for: Dose Efficiency

Total 21863 results

Metronome Therapeutics

Unknown

Safety Study of Oral Vinorelbine in Subjects With Non-Hematologic Malignancies

Nonhematologic Malignancies

United States
AstraZeneca

Completed

Investigate the Effect on the QT/QTc Interval of Repeated and Escalating Doses of AZD3480 During 6 Days (TQT)

Healthy
University of British Columbia

Completed

Optimum Dose of Remifentanil for Intubation in Small Children

Endotracheal Intubation

Canada
U.S. Army Office of the Surgeon General
U.S. Army Medical Research and Development Command; Military Infectious Diseases...

Completed

Phase II Dose Ranging Study of Artesunate

Falciparum Malaria | Uncomplicated Malaria

Kenya, Thailand
Assistance Publique - Hôpitaux de Paris

Completed

Effects of Sodium Intake on (PK/PD) Relationship of a Single Dose of a Renin Angiotensin System-Blocker

Healthy

France
Marigot Ltd.

Completed

Effects of Aquamin F on NSAID Dose Reduction in Osteoarthritis of the Knee

Osteoarthritis of the Knee

United States
PharmAthene UK Limited
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

One Year Study to Evaluate Three Different Adjuvanted Doses of the Recombinant Plague Vaccine (rF1 and rV Antigens)

Plague

United States, United Kingdom
PharmAthene UK Limited
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Phase II Study of Range and Schedule of rPA Doses

Prevention of Bacillus Anthracis (Anthrax) Infection

United Kingdom
Johns Hopkins University

Completed

Phase II Study of High-Dose Cyclophosphamide in Patients With Severe Autoimmune Hematologic Disease

Autoimmune Diseases | Purpura, Thrombocytopenic | Anemia, Hemolytic, Autoimmune | Felty Syndrome

United States
Western Galilee Hospital-Nahariya

Completed

Addition of Heparin to Taurolock-TM CLS in HD Patients With TCC Dose it Improve Catheter Patency Problems ?

Hemodialysis | End Stage Renal Disease

Israel
Bader, Ted, M.D.

Completed

Dose Finding Trial of Rosuvastatin and Atorvastatin Versus Hepatitis C

Hepatitis C

United States
Biogen

Terminated

How Side Effects of Avonex Are Affected by Gradually Increasing to Full Dose vs Starting at Full Dose (TODAY)

Relapsing Remitting Multiple Sclerosis

Australia
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Efficiency of Physiotherapeutic Care in Parkinson's Disease

Parkinson's Disease

Netherlands
Ludwig-Maximilians - University of Munich

Completed

Influence of Hydrocortisone on Immunologic Markers and Health Care Related Quality of Life in Patients After Cardiac Surgery

Systemic Inflammatory Response Syndrome | Posttraumatic Stress Disorder

Germany
Rigshospitalet, Denmark

Unknown

Acute Haemodynamic Effects of Treatment With Angiotensin Converting Enzyme (ACE)-Inhibitors in Patients With Symptomatic Aortic Stenosis

Aortic Stenosis

Denmark
Bionovo

Terminated

Phase I Study to Evaluate the Safety and Efficacy of MF101 as Well as the Pharmacokinetics of Its Key Active Components

Healthy

United States
National Institute on Aging (NIA)

Completed

Brain Imaging and Mental Disorders of Aging Intervention

Cognition Disorders

United States
Pharmaxis

Completed

Mannitol Dose Response Study in Cystic Fibrosis

Cystic Fibrosis

Canada, Argentina
Shanghai Jiao Tong University School of Medicine

Unknown

To Evaluate the Efficiency and Safety of Quetiapine Fumarate in the Treatment of Acute Manic Patients With Bipolar Disorder.

Bipolar Disorder

China
Deutsches Herzzentrum Muenchen

Unknown

Prospective Randomized Trial On RadiaTion Dose Estimates Of CT AngIOgraphy In PatieNts Scanned With A 100kV Protocol (PROTECTION-II)

Coronary Disease

Germany
Deutsches Herzzentrum Muenchen

Unknown

Prospective Randomized Trial On RadiaTion Dose Estimates Of CT AngIOgraphy In PatieNts Scanned With A Sequential Scan Protocol (PROTECTION-III)

Coronary Disease

Germany
Hvidovre University Hospital
Pfizer

Completed

The Effect of Low-Dose Human Growth Hormone Therapy in HIV Infected Patients

HIV Infections | Lipodystrophy

Denmark
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I/II Trial of Ribavirin (With Escalation) + Isoprinosine in Asymptomatic HIV-Viremic Patients

HIV Infections

United States
Rigshospitalet, Denmark
Henrik Jensen, Dept. of Oncology, Vejle Sygehus, Vejle, Denmark

Completed

Gemcitabine, Oxaliplatin and Capecitabine in Patients With Advanced Cholangiocarcinoma

Cholangiocarcinoma

Denmark
Intermountain Health Care, Inc.
Deseret Foundation; LDS Hospital Cardiovascular Research

Completed

A Pharmacogenetic Study of Warfarin Dosing, "The COUMA-GEN Study"

Atrial Fibrillation | Deep Vein Thrombosis | Pulmonary Embolism

United States
National Taiwan University Hospital

Terminated

Bi-Weekly Docetaxel Plus 24-Hour Infusion of High-Dose 5-Fluorouracil / Leucovorin (HDFL) for Inoperable Advanced or Metastatic Gastric Cancer

Gastric Cancer

Taiwan
Allergan
Sirna Therapeutics Inc.

Completed

A Dose Escalation Trial of an Intravitreal Injection of Sirna-027 in Patients With Subfoveal Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD)

Age-Related Macular Degeneration | Choroidal Neovascularization

United States
Bristol-Myers Squibb

Completed

A Multiple-Dose Study of Sinemet® CR (Carbidopa/Levodopa) in Healthy Subjects

Parkinson's Disease

Canada
Sunnybrook Health Sciences Centre

Unknown

Effects of Technique on the Local Anesthetic Dose Required for Interscalene Brachial Plexus Block

Arthroscopic Shoulder Surgery

Canada
Hospital General de Requena
Esteve

Completed

Efficacy of Budesonide-Formoterol in Bronchiectasis

Bronchiectasis

Spain
HemaQuest Pharmaceuticals Inc.

Completed

A Phase 1, Single-Dose Safety and Pharmacokinetic Study of Sodium ST20 in Healthy Volunteers

Healthy

United States
ACU Medical Technologies Ltd

Completed

Testing the Efficiency of a Device Meant to Relieve Labour Pain

Labour Pain

Israel
Amgen

Completed

Same Day Dosing of Pegfilgrastim in Breast Cancer Patients Undergoing Chemotherapy (TAC)

Breast Cancer | Neutropenia | Fever
Boehringer Ingelheim

Completed

An Open-Label, Staggered Rising Dose Cohort Study Assessing the Pharmacokinetics, Safety, and Tolerance of BI-RG-587 in Combination With Zidovudine in Patients With HIV Infection (CD4+ Cell Count < 400/mm3)

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Procept

Completed

Safety and Tolerability of the Vaginal Gel PRO 2000/5

HIV Infections

United States
Alcon Research

Completed

Dose Response Study of AL-37807 Ophthalmic Solution in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States
MedImmune LLC

Completed

Open-Label, Dose-Escalation Study of 2 to 5 IM Doses of MEDI-524 at 3 mg/kg or 15 mg/kg; Children to be Followed for 90 Days After Their Last Dose of MEDI-524

Respiratory Syncytial Virus Infections

Chile, Argentina
Academy Military Medical Science, China
Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Unknown

A Randomised,Multi-Center Study of Docetaxol Plus Capecitabine or Cisplatin in Anthracycline-Pretreated Patients With Advanced Breast Cancer

Advanced Breast Cancer
OPKO Health, Inc.

Completed

Open Label Study for the Evaluation of Tolerability of Five Dose Levels of Cand5

Macular Degeneration

United States
GERCOR - Multidisciplinary Oncology Cooperative...

Unknown

Docetaxel or Paclitaxel in Treating Women With Unresectable Locally Advanced or Metastatic Breast Cancer

Breast Cancer

France, Luxembourg
GERCOR - Multidisciplinary Oncology Cooperative...

Unknown

Gemcitabine and Docetaxel in Treating Patients With Inoperable Stage IIIB or Stage IV Non-Small Cell Lung Cancer

Lung Cancer

France
GERCOR - Multidisciplinary Oncology Cooperative...

Unknown

Docetaxel and Oxaliplatin in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer

Ovarian Cancer

France
GERCOR - Multidisciplinary Oncology Cooperative...

Unknown

Docetaxel and Epirubicin as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Adenocarcinoma of the Stomach

Gastric Cancer

France
Targacept Inc.

Completed

A Safety and Tolerability Single Ascending Dose Study in Healthy Volunteers (SRD)

Healthy

France
Hadassah Medical Organization
International Anesthesia Research Society (IARS)

Completed

Antepartum Chronic Epidural Therapy (ACET) to Improve Blood Flow to the Uterus, Placenta and Baby in Pre-Eclampsia and Intrauterine Growth Restriction

Pre-Eclampsia | Fetal Growth Retardation

Israel
University of Cologne
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.; German Hodgkin...

Terminated

Study of Bortezomib (Velcade) in Combination With Dexamethasone to Treat Patients With Relapsed Hodgkin's Lymphoma

Hodgkin Disease

Germany
University of Turku
Leiden University Medical Center

Completed

The Effect of Right Ventricular Pacing on Myocardial Oxidative Metabolism and Efficiency

Bradycardia

Finland
Hospices Civils de Lyon

Completed

Botulinum Toxin Efficiency on Spasticity of Rectus Femoris and Semitendinosus Muscles as Functional Agonist and Antagonist Muscles

Cerebral Palsy

France
YM BioSciences

Completed

Study of Single and Multiple Doses of Inhaled AeroLEF (Liposome-Encapsulated Fentanyl)in Healthy Subjects (LEF-2495)

Healthy

Canada
Avant Immunotherapeutics

Completed

Dose Ranging Study to Determine the Safety, Reactogenicity and Immunogenicity of Typhoid Fever Vaccine (Ty800) in Healthy Adult Subjects

Typhoid Fever

United States

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