Clinical Trials Sponsored by Repros Therapeutics Inc.

Total 3001 results

Esperion Therapeutics, Inc.
The Cleveland Clinic

Completed

Evaluation of Major Cardiovascular Events in Participants With, or at High Risk for, Cardiovascular Disease Who Are Statin Intolerant Treated With Bempedoic Acid (ETC-1002) or Placebo (CLEAR Outcomes)

Cardiovascular Diseases | Statin Adverse Reaction

Belgium, Germany, United States, Austria, Estonia, Mexico, New Zealand, Spain, Russian Federation, Netherlands, Hungary, Australia, Denmark, South Africa, United Kingdom, Bulgaria, Argentina, Romania, Turkey, Croatia, Serbia, Canada, Lithuan... and more
CoA Therapeutics, Inc., a BridgeBio company

Terminated

A First in Human, Dose Escalation Study to Evaluate the Safety and Tolerability of BBP-671 in Healthy Volunteers and Patients With Propionic Acidemia or Methylmalonic Acidemia

Healthy Volunteers | Propionic Acidemia | Methylmalonic Acidemia | Organic Acidemia

United States
NYU Langone Health
Leap Therapeutics, Inc.

Terminated

A Parallel Arm Phase 1b/2a Study of DKN-01 as Monotherapy or in Combination With Docetaxel for the Treatment of Advanced Prostate Cancer With Elevated DKK1

Prostate Cancer

United States
BioXcel Therapeutics Inc
Cognitive Research Corporation

Completed

Dexmedetomidine in the Treatment of Agitation Associated With Dementia (TRANQUILITY II)

Dementia | Agitation

United States
Candel Therapeutics, Inc.
NYU Langone Health

Active, not recruiting

CAN-2409 Plus Prodrug With Standard of Care Immune Checkpoint Inhibitor for Stage III/IV NSCLC

Non Small Cell Lung Cancer

United States
Sarepta Therapeutics, Inc.
Hoffmann-La Roche

Active, not recruiting

A Gene Transfer Therapy Study to Evaluate the Safety and Efficacy of Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD) (EMBARK)

Duchenne Muscular Dystrophy

United States, Japan, Taiwan, Belgium, Spain, Germany, Hong Kong, Italy, United Kingdom
BioXcel Therapeutics Inc
Cognitive Research Corporation

Terminated

An Efficacy, and Safety Study Of BXCL501 For The Treatment Of Agitation Associated With Dementia

Dementia | Agitation

United States
Sarepta Therapeutics, Inc.
Hoffmann-La Roche

Enrolling by invitation

A Gene Transfer Therapy Study to Evaluate the Safety of and Expression From Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD) (ENDEAVOR)

Muscular Dystrophy, Duchenne

United States
University of Washington
TG Therapeutics, Inc.

Terminated

Umbralisib and Pembrolizumab in Treating Patients With Relapsed or Refractory Classical Hodgkin Lymphoma

Hodgkin's Lymphoma

United States
Shanghai Pudong Hospital
UTC Therapeutics Inc.

Withdrawn

Novel CAR-T Cell Therapy in the Treatment of Hematopoietic and Lymphoid Malignancies

Acute Myeloid Leukemia (AML) | Multiple Myeloma (MM) | B-cell Non-Hodgkin's Lymphoma (B-NHL) | T-Cell Leukemia/Lymphoma, Adult | B-cell Acute Lymphoblastic Leukemia (B-ALL)

China
BioXcel Therapeutics Inc
Cognitive Research Corporation

Completed

Sub-Lingual Dexmedetomidine in Agitation Associated With Schizophrenia

Schizophrenia | Agitation

United States
NovelMed Therapeutics
Labcorp Drug Development Inc

Completed

First-in-Human (FIH) Clinical Study of NM8074 in Healthy Adult Volunteers

Healthy

United States
Edgewise Therapeutics, Inc.
Worldwide Clinical Trials

Completed

A Study to Assess Safety, Tolerability, and PK of EDG-5506 in Healthy Volunteers and Becker Muscular Dystrophy Adults

Becker Muscular Dystrophy | Healthy Volunteer

United States
BioXcel Therapeutics Inc
Cognitive Research Corporation

Withdrawn

Study of BXCL501 In Agitation Associated With Delirium in ICU Patients

Delirium | Agitation

United States
Swedish Orphan Biovitrum
Bioverativ Therapeutics Inc.

Completed

Study of rFVIIIFc for Immune Tolerance Induction (ITI) in Haemophilia A Patients With Inhibitors Who Have Failed Previous ITI Therapies (ReITIrate)

Hemophilia A

Ireland, United Kingdom, Germany, United States, Canada, Slovenia, Sweden
University of Hawaii
Tobira Therapeutics, Inc.

Completed

Effect of Cenicriviroc on HIV Neurocognitive Impairment

AIDS Dementia Complex | Human Immunodeficiency Virus | HIV-1-Associated Cognitive Motor Complex

United States
Imperial College London
Melinta Therapeutics, Inc.

Terminated

A Study to Evaluate the Anti-inflammatory Effects of Solithromycin in Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

United Kingdom
Syneos Health
F-star Therapeutics, Inc.

Completed

A Multiple Ascending Dose Phase I Study of SB 9200 in Treatment Naïve Adults With Chronic Hepatitis C Infection

Hepatitis C Infection

Australia, New Zealand
Alcresta Therapeutics, Inc.
Cystic Fibrosis Foundation

Completed

Absorption and Safety With Sustained Use of RELiZORB Evaluation (ASSURE) Study (ASSURE)

Cystic Fibrosis

United States
Eyecure Therapeutics Inc.
Beijing Tongren Hospital

Unknown

Treatment of RP and LCA by Primary RPE Transplantation

Leber Congenital Amaurosis, Retinitis Pigmentosa

China
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Measure Liver Fat Content After ISIS 301012 (Mipomersen) Administration

Metabolic Diseases | Congenital Abnormalities | Infant, Newborn, Diseases | Genetic Diseases, Inborn | Dyslipidemias | Metabolism, Inborn Errors | Lipid Metabolism Disorders | Hypercholesterolemia | Hyperlipidemias | Lipid Metabolism, Inborn Errors | Hypobetalipoproteinemias | Hypolipoproteinemias | Hypolipopro... and other conditions

Netherlands
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Safety and Efficacy of Mipomersen in Patients With Severe Hypercholesterolemia on a Maximally Tolerated Lipid-Lowering Regimen and Who Are Not on Apheresis

Hypercholesterolemia | Coronary Heart Disease

South Africa, Germany, United States, United Kingdom, Canada, Czech Republic
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Open Label Extension of ISIS 301012 (Mipomersen) to Treat Familial Hypercholesterolemia

Metabolic Diseases | Congenital Abnormalities | Infant, Newborn, Diseases | Genetic Diseases, Inborn | Dyslipidemias | Metabolism, Inborn Errors | Lipid Metabolism Disorders | Hypercholesterolemia | Hyperlipidemias | Hyperlipoproteinemias | Lipid Metabolism, Inborn Errors | Hyperlipoproteinemia Type II | Metabolic... and other conditions

United States
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Study to Assess the Effects of Mipomersen on Lipid and Lipoprotein Metabolism in Healthy Subjects

Healthy Volunteer

United States
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Study of ISIS 301012 (Mipomersen) in Heterozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy

Hypercholesterolemia, Familial

United States, Netherlands
Imperial College London
Nuon Therapeutics, Inc.

Withdrawn

Effects of Tranilast on Pharmacokinetics of Methotrexate (MTX) in Patients With Rheumatoid Arthritis (RA)

Rheumatoid Arthritis
University of Rochester
EKR Therapeutics, Inc

Completed

Safety and Efficacy of DepoDur in Lumbar Spine Surgery Patients (DepoDur)

Lumbar Spine Surgery

United States
PluroGen Therapeutics, Inc
Arkios BioDevelopment International

Completed

Topical PluroGel PN for the Treatment of Mildly Infected Diabetic Foot Ulcers

Diabetic Foot Ulcer | Infection

United States
Astellas Pharma Inc
Perseid Therapeutics LLC

Completed

A Study to Assess the Receptor Occupancy of CD86 and CD80 in Subjects With Rheumatoid Arthritis Initiating Abatacept

Rheumatoid Arthritis

United States
Biohaven Therapeutics Ltd.

Not yet recruiting

Long-term Safety and Tolerability of BHV-7000

Focal Epilepsy
Biohaven Therapeutics Ltd.

Recruiting

Efficacy and Safety Study of BHV-7000 Monotherapy in Major Depression

Major Depressive Disorder

United States
Biohaven Therapeutics Ltd.

Recruiting

A Phase 1/2 Study of PBI-410 in Advanced Solid Tumors

Solid Tumor

United States
Biohaven Therapeutics Ltd.

Recruiting

A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy (RISE 2)

Focal Epilepsy

United States
University of Pennsylvania
Axsome Therapeutics, Inc.

Recruiting

Solriamfetol and CBT-I in Patients With Insomnia Disorder

Insomnia

United States
Calcilytix Therapeutics, Inc., a BridgeBio company

Recruiting

Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1 (CALIBRATE)

Autosomal Dominant Hypocalcemia (ADH)

United States, Australia, United Kingdom, Denmark, Italy, France, Japan, Taiwan, Canada, Czechia, Netherlands
Indaptus Therapeutics, Inc
Translational Drug Development

Recruiting

DECOY20 Study in Patients With Advanced Solid Tumors

Solid Tumor, Adult

United States
Cancer Research UK
Teon Therapeutics, Inc.

Recruiting

TT-702 in Patients With Advanced Solid Tumours. (CURATE)

Advanced Solid Tumors

United Kingdom
European Myeloma Network
Karyopharm Therapeutics Inc

Recruiting

A Study of Combination of Selinexor, Pomalidomide, and Dexamethasone (SPd) Versus Elotuzumab, Pomalidomide, and Dexamethasone (EloPd) in Subject With Previously Treated Multiple Myeloma

Multiple Myeloma

Spain, United States, Germany, Netherlands, Greece, France, Italy
BioXcel Therapeutics Inc
Cognitive Research Corporation

Recruiting

Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder

Schizophrenia | Bipolar Disorder I | Schizo-Affective Disorder | Schizophreniform; Schizophrenic | Bipolar Disorder II

United States
Tufts Medical Center
Partner Therapeutics, Inc.

Recruiting

A Study of Sargramostim Plus Pembrolizumab With or Without Pemetrexed in Patients With Advance Non-small Cell Lung Cancer After Completion of Chemoimmunotherapy

Advanced Lung Non-Small Cell Carcinoma | Non-Small Cell Carcinoma of Lung, TNM Stage 4

United States
University of Louisville
Integrative Therapeutics, Inc.

Recruiting

Peppermint Oil for the Treatment of Interstitial Cystitis / Bladder Pain Syndrome

Interstitial Cystitis

United States
Sarepta Therapeutics, Inc.
Hoffmann-La Roche

Enrolling by invitation

A Long-term Follow-up Study of Participants Who Received Delandistrogene Moxeparvovec (SRP-9001) in a Previous Clinical Study (EXPEDITION)

Duchenne Muscular Dystrophy

United States, Spain
University of Nebraska
Partner Therapeutics, Inc.

Active, not recruiting

Biomarker Validation Following Sargramostim Treatment in Parkinson's Disease

Parkinson's Disease and Parkinsonism

United States
University of Utah
Karyopharm Therapeutics Inc

Active, not recruiting

Selinexor in Myelofibrosis Refractory or Intolerant to JAK1/2 Inhibitors (ESSENTIAL)

Primary Myelofibrosis | Post-polycythemia Vera Myelofibrosis | Post-essential Thrombocythemia Myelofibrosis

United States
BioXcel Therapeutics Inc
Cognitive Research Corporation

Terminated

Dexmedetomidine in the Treatment of Agitation Associated With Dementia (TRANQUILITY III)

Dementia | Agitation

United States
BioXcel Therapeutics Inc
Worldwide Clinical Trials

Active, not recruiting

Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia and Bipolar Disorder (SERENITY III)

Schizophrenia | Schizoaffective Disorder | Bipolar I Disorder | Bipolar II Disorder | Agitation,Psychomotor | Schizophreniform Disorders

United States
Promontory Therapeutics Inc.
Pfizer; EMD Serono

Completed

A Dose Escalation and Confirmation Study of PT-112 in Advanced Solid Tumors in Combination With Avelumab (PAVE-1)

Non-Small Cell Lung Cancer (NSCLC)

United States, Switzerland
Calcilytix Therapeutics, Inc., a BridgeBio company

Completed

Safety, Tolerability, and Efficacy of Encaleret in Participants With Autosomal Dominant Hypocalcemia (ADH) Type 1

Autosomal Dominant Hypocalcemia (ADH)

United States
IGM Biosciences, Inc.
ADC Therapeutics S.A.

Active, not recruiting

A Study of Imvotamab Monotherapy and in Combination in Subjects With Relapsed/Refractory Non-Hodgkin Lymphoma

Follicular Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Non-Hodgkin Lymphoma | DLBCL

United States, Korea, Republic of, Spain, France, Australia, Czechia, Italy
University of Leicester
Travere Therapeutics, Inc.

Active, not recruiting

A Study of the Safety and Activity of Sparsentan for the Treatment of Incident Patients With Immunoglobulin A Nephropathy (SPARTAN)

Immune System Diseases | Autoimmune Diseases | Kidney Diseases | Glomerulonephritis | Immunoglobulin A Nephropathy | Glomerulonephritis, IGA

United Kingdom

Clinical Trials Sponsored by Repros Therapeutics Inc.

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