Search clinical trials for: PF-04531083

Total 1296 results

Pfizer

Completed

A Study to Evaluate the Pharmacodynamic Effects of Single Oral Doses of PF-06648671 on β-Amyloid (Aβ) Concentrations in Cerebrospinal Fluid (CSF)

Healthy Subjects

United States
Pfizer

Completed

A Study To Investigate The Absorption, Distribution, Metabolism, And Excretion Of [14c]PF-06463922 In Healthy Male Volunteers

Healthy

United States
University Health Network, Toronto
Pfizer

Completed

Study to Assess Biomarkers in Patients With Resectable Oral Cavity Cancer Randomized to Receive Preoperative Treatment

Oral Cavity Cancer

Canada
Pfizer

Completed

A Study To Understand How Radiolabelled PF-04449913 Is Taken Up By The Body, Broken Down And Then Removed From The Body

Healthy

United States
Pfizer

Withdrawn

Study Of Safety, Tolerability And Effects Of PF-05175157 In Adults With Moderate To Severe Acne Vulgaris

Acne Vulgaris
Pfizer

Completed

A Study to Evaluate Safety, Toleration and Time Course of Plasma Concentration of Multiple Oral Doses of PF-06273340 in Healthy Subjects of Two AgeGroups, Aged 18-55 Years (Group 1) and Aged 56-75 Years (Group 2)

Healthy

Belgium
Pfizer

Completed

Cold Pressor Test is Used in This Study to Assess the Effect of PF-06305591 on Pain Intensity Evoked by Cold in Healthy Male Subjects

Healthy

Belgium
Quark Pharmaceuticals
Pfizer

Completed

Study of PF-04523655 (REDD14NP) In Subjects With Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (Wet AMD)

Age-Related Macular Degeneration

United States, Israel
Pfizer

Completed

PK And Safety Study Of PF-04171327 In Healthy Japanese And Western Subjects In Fasting And Fed Conditions

Healthy

United States
Pfizer

Completed

A First In Human Study In Healthy People To Evaluate Safety, Toleration And Time Course Of Plasma Concentration Of Single Inhaled Doses Of PF-05212372.

Pharmacokinetics | Safety | Phase 1 | Single Dose | Toleration

Belgium
Pfizer

Completed

Single Dose Escalation Study of PF-05190457 in Healthy Volunteers

Diabetes Mellitus, Type II

Belgium
Pfizer

Completed

A Phase I, Single Dose Study Of PF-04360365 In Japanese Patients With Mild To Moderate Alzheimer's Disease

Alzheimer's Disease

Japan
Pfizer

Completed

A Study In Healthy People To Investigate The Safety, Toleration And Time Course Of Blood Concentrations Of Multiple Doses Of PF-03654764, Given By Mouth

Healthy

Singapore
Pfizer

Completed

A Study Of Adjunctive Treatment Of Cognitive Deficits In Schizophrenia

Schizophrenia

United States
Pfizer

Active, not recruiting

PF-07284892 in Participants With Advanced Solid Tumors

Solid Tumor

United States
Pfizer

Completed

Single Dose Study With Unlabeled Dose and 14C-labeled Microdose of PF-06700841 in Healthy Male Subjects

Healthy Male Subjects

Netherlands
Pfizer

Recruiting

A Study to Learn About the Study Medicine (PF-06823859) in Adults With Active CLE or SLE With Skin Symptoms.

Lupus Erythematosus, Systemic | Lupus Erythematosus, Cutaneous

United States, Spain, Taiwan, Canada, Greece
Pfizer

Recruiting

A Study to Learn How Different Amounts of the Study Medicine Called PF-07328948 Are Tolerated and Act in the Body in Healthy Adults

Healthy

United States, Belgium
National Institute of Mental Health (NIMH)

Recruiting

[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET

Depression

United States
Pfizer

Recruiting

Lorlatinib Continuation Study

NSCLC | Non-Small-Cell Lung Cancer

Spain, Taiwan, France, China, Singapore, Japan, United States
Pfizer

Active, not recruiting

A Study of Lorlatinib in ALK Inhibitor-Treated ALK-Positive NSCLC in China

Carcinoma, Non-Small-Cell Lung

China
NCIC Clinical Trials Group
Pfizer

Completed

PF-00299804 in Stage IIIB or Stage IV Non-Small Cell Lung Cancer Not Responding to Standard Therapy for Advanced or Metastatic Cancer

Lung Cancer

Taiwan, Canada, Australia, Italy, New Zealand, United States, Thailand, Korea, Republic of, Brazil, Argentina, Philippines, Peru
Pfizer

Completed

Study to Evaluate Safety and Tolerability of PF-07242813 in Healthy Participants and Participants With Atopic Dermatitis

Atopic Dermatitis

United States
Yale University

Completed

Translational Neuroscience Optimization of GlyT1 Inhibitor (NCATS)

Cognitive Impairments Associated With Schizophrenia

United States
Pfizer

Completed

Study Of Single And Multiple Ascending Doses Of PF-07054894 In Healthy Adult Participants

Healthy

Belgium
Pfizer

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-06882961 in Japanese Adults With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Japan
Pfizer

Completed

Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The Knee

Osteoarthritis, Knee

Korea, Republic of, United States
Pfizer

Completed

Single Ascending Dose Study of Intravenous Infusion of PF 07304814 in Healthy Adult Participants

Healthy

United States
Pfizer

Completed

A Study Of PF-04447943 Compared To Placebo In Subjects With Mild To Moderate Alzheimer's Disease

Alzheimer's Disease

United States, Canada, Chile, Czechia
Pfizer

Completed

4-Week, Multiple-dose, Dose-escalating Study In Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

United States
Biogen
Yale University

Completed

A Study To Assess Effects Of PF-04958242 On Bold Functional Magnetic Resonance Imaging During Working Memory Activation And Arterial Spin Labeling At Rest In Healthy Subjects

Healthy Volunteer

United States
Pfizer

No longer available

Expanded Access For Lorlatinib For Patients With Non Small Cell Lung Cancer ALK Positive or ROS1 Positive

Non Small Cell Lung Cancer ALK Positive or ROS1 Positive

United States
Pfizer

Withdrawn

Study Evaluating The Safety And Efficacy Of PF-03654746 In Adult Subjects With Tourette's Syndrome

Tourette's Syndrome

United States
Pfizer

Completed

Study To Investigate Effect Of A New Drug (PF-00446687) In Post-Menopausal Women Who Suffer From Sexual Dysfunction.

Female Sexual Dysfunction

Norway, Denmark, Sweden
Pfizer
Alzheimer's Disease Cooperative Study (ADCS)

Completed

A Phase 2 Study Evaluating The Efficacy And Safety Of PF 04494700 In Mild To Moderate Alzheimer's Disease

Alzheimer's Disease

United States
Pfizer

Completed

A Phase 1 Single/Multiple Dose Study Of PF-06293620 To Assess Safety, Tolerability And Pharmacokinetics In Subjects With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Pfizer

Terminated

Single Dose Study of PF-06815345 in Healthy Subjects

Hypercholesterolemia

Belgium
Pfizer

Completed

Study To Evaluate The Safety, Tolerability, And Pharmacokinetics Of Oral Pf-06650833 In Healthy Subjects

Healthy

United States
Pfizer

Completed

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single Doses of PF-06852231 in Healthy Subjects

Healthy Volunteers

Belgium
Pfizer

Terminated

Double Blind, Randomized, 3 Week Inpatient Study To Evaluate The Safety & Efficacy Of PF-02545920 Compared With Placebo

Schizophrenia

United States
Pfizer

Completed

Study Evaluating The Safety, Tolerability And Brain Function Of 2 Doses Of PF-0254920 In Subjects With Early Huntington's Disease

Huntington's Disease

France
Pfizer

Completed

Randomized, Placebo Controlled Study Of The Efficacy And Safety Of PF-02545920 In Subjects With Huntington's Disease

Huntington's Disease

United States, Germany, United Kingdom, Canada, Poland
Pfizer

Completed

A Multiple Dose Safety And Pharmacokinetic (PK) Study Of PF-06427878 In Overweight-Obese, Otherwise Healthy Subjects

Healthy Volunteers

United States
Pfizer

Completed

A Trial To Assess The Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Of Single Doses Of PF-04937319 In Subjects With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Pfizer

Terminated

An Evaluation Of PF-03715455 In Moderate To Severe Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

United Kingdom
Pfizer

Terminated

A Study To Assess the Effects Of PF-04457845 On BOLD fMRI In Subjects With Post Traumatic Stress Disorder

Post-Traumatic Stress Disorder

United States
Pfizer

Completed

Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Study Of PF-06291874 As Oral Monotherapy To Treat Adults With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type II

United States
Pfizer

Completed

Effect Of Single-Dose PF-05175157 On Metabolic And Cardiopulmonary Parameters

Healthy

United States
Seoul National University Hospital
Pfizer

Completed

PF-00299804 Monotherapy in Patients With HER-2 Positive Advance Gastric Cancer (PF299804-AGC)

Advanced Gastric Cancer | HER2

Korea, Republic of
Pfizer

Completed

Efficacy, Safety And Tolerability Study In Subjects With Parkinson's Disease

Parkinson's Disease

United States

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