Search clinical trials for: Talazoparib Oral Capsule

Total 11028 results

University of Zurich
National Center of Cardiology and Internal Medicine named after academician...

Completed

Effect of Acetazolamide on Right Ventricular Function at Rest in Patients With Respiratory Disease at Altitude

Chronic Obstructive Pulmonary Disease

Kyrgyzstan
University of Zurich
National Center of Cardiology and Internal Medicine named after academician...

Completed

Effect of Acetazolamide on Right Ventricular Function During Exercise in Patients With Respiratory Disease at Altitude

Chronic Obstructive Pulmonary Disease

Kyrgyzstan
University of Zurich
National Center of Cardiology and Internal Medicine, Kyrgyz Republic

Recruiting

Effect of Acetazolamide on Right Heart Function at Rest in Lowlanders With COPD Traveling to High Altitude

Chronic Obstructive Pulmonary Disease | Altitude Sickness | Right Heart Function

Kyrgyzstan
University of Zurich
National Center of Cardiology and Internal Medicine, Kyrgyz Republic

Active, not recruiting

Acetazolamide to Prevent Impending Altitude-illness in Patients With COPD

Chronic Obstructive Pulmonary Disease | Altitude Sickness | Altitude Hypoxia

Kyrgyzstan
Pfizer

Terminated

Avelumab and Talazoparib in Untreated Advanced Ovarian Cancer (JAVELIN OVARIAN PARP 100)

Ovarian Cancer

Korea, Republic of, United States, Singapore, Taiwan, Japan, Italy, Australia, Belgium, Ireland, Russian Federation
Dignity Sciences Ltd.

Completed

Oral DS107 in Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

United States, Canada
Cale Andrew Jacobs, PhD
Massachusetts General Hospital

Withdrawn

GetHealthy-OA: A Program to Improve Pain and Function for Patients With Knee Osteoarthritis, Obesity, and Depression

Depression | Knee Osteoarthritis | Obese

United States
Genentech, Inc.

Completed

An Absolute Bioavailability Study in Healthy Participants Comparing Oral to Intravenous Administration of GDC-0973 (Cobimetinib)

Healthy Volunteers
McGill University Health Centre/Research Institute...
Centre de Recherche du Centre Hospitalier de l'Université de Montréal; CIHR... and other collaborators

Terminated

Cannabinoids in PLWHIV on Effective ART

HIV Infections

Canada
PhytoTech Therapeutics, Ltd.

Unknown

Evaluation of the Safety, Tolerability, and Efficacy of Orally Administered PTL201 in MS Patients With Spasticity-related Symptoms

Multiple Sclerosis

Israel
Cheng-Chung Wei
Golden Biotechnology Corporation

Unknown

A Randomized, Placebo-controlled Trial of Antroquinonol in Patients With Chronic Hepatitis B

Chronic Hepatitis B

Taiwan
Pfizer

Terminated

Talazoparib For Neoadjuvant Treatment Of Germline BRCA1/2 Mutation Patients With Early Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer

Early Breast Cancer

United States
University of Zurich
National Center of Cardiology and Internal Medicine named after academician...

Active, not recruiting

Effect of Acetazolamide on Right Heart Function During Exercise in Lowlanders Older Than 40 Years at Altitude

Altitude Hypoxia

Kyrgyzstan
University of Zurich
National Center of Cardiology and Internal Medicine named after academician...

Completed

Effect of Acetazolamide on Cognition in Patients With Respiratory Disease at Altitude

Chronic Obstructive Pulmonary Disease (COPD)

Kyrgyzstan
University of Zurich
National Center of Cardiology and Internal Medicine named after academician...

Completed

Effect of Acetazolamide on Sleep Related Breathing Disturbances in Patients With Respiratory Disease at Altitude

Chronic Obstructive Pulmonary Disease

Kyrgyzstan
Pfizer

Completed

STUDY OF TALAZOPARIB MONOTHERAPY IN CHINESE PARTICIPANTS WITH ADVANCED SOLID TUMORS

Neoplasms

China
Aelis Farma
National Institute on Drug Abuse (NIDA)

Active, not recruiting

Effect of AEF0117 on Treatment-seeking Patients With Cannabis Use Disorder (CUD) (SICA2)

Marijuana Abuse

United States
PETHEMA Foundation

Active, not recruiting

Study to Investigate the Use of Acalabrutinib in the Treatment of Patients With Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia- Binet Staging System

Spain
Yale University

Completed

Development of Agents to Diminish the Risk of Hypoglycemia-induced Brain Injury in Type 1 Diabetes

Hyperglycaemia (Diabetic)

United States
Jacksonville University
Specnova, inc

Unknown

Polyphenol Rich Supplementation on Markers of Recovery From Intense Resistance Exercise (PRSRE)

Muscle Soreness

United States
Hospices Civils de Lyon

Completed

Efficacy of Nintedanib Per os as a Treatment for Epistaxis in HHT Disease. (EPICURE)

Telangiectasia, Hereditary Hemorrhagic | Rendu Osler Disease

France
POM Wonderful LLC
Target Health Inc.

Completed

POMx In the Treatment of Erectile Dysfunction

Erectile Dysfunction

United States
Chung Shan Medical University
Golden Biotechnology Corporation

Terminated

A Phase II, Placebo-controlled Trial Evaluating the Efficacy of Antroquinonol in Patients With Atopic Dermatitis

Atopic Dermatitis

Taiwan
Goranka Radmilović

Recruiting

The Effect of Orally Administered L- Arginine on Quadriceps Strenght in Healthy Smokers

Spirometry | Qadriceps Muscle

Croatia
Abivax S.A.

Completed

ABX464 in Subjects With Moderate to Severe Active Ulcerative Colitis

Ulcerative Colitis

Belgium
Biogen

Completed

Study Of The PF-04958242 Blood Concentrations Of A Capsule Formulation Of PF-04958242 Compared To A Solution Formulation

Healthy

United States
Kalyra Pharmaceuticals, Inc.
United States Department of Defense; PRA Health Sciences

Terminated

A Single and Multiple Ascending Dose Study in Healthy Subjects to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of KP-1199

Analgesia

United States
Pfizer

Active, not recruiting

A Phase 1 Study Of Talazoparib, PARP Inhibitor, In Japanese Patients With Advanced Solid Tumors

Neoplasms | Breast Neoplasms

Japan
Millennium Pharmaceuticals, Inc.

Completed

Study to Assess Absolute Bioavailability (ABA) of TAK-906 and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of [14C]-TAK-906 in Healthy Male Participants

Healthy Volunteers

United States
Weill Medical College of Cornell University
Agency for Healthcare Research and Quality (AHRQ)

Completed

Trial of an Intervention to Improve Metformin Persistence and Adherence (TreatMet)

Tolerance | Metformin Adverse Reaction

United States
Barnes-Jewish Hospital
Washington University School of Medicine

Terminated

Concentrated Saline Infusions and Increased Dietary Sodium With Diuretics for Heart Failure With Kidney Dysfunction

Renal Insufficiency | Congestive Heart Failure

United States
Joseph Jurcic
Bristol-Myers Squibb

Terminated

Combination of Fedratinib and Decitabine for Myeloproliferative Neoplasms (MPN)- Accelerated Phase (AP)/Blast Phase (BP)

Myeloproliferative Neoplasm

United States
Virginia Commonwealth University

Withdrawn

HDAC Inhibitor Augmentation to Clozapine

Schizophrenia

United States
University Hospital, Ghent

Completed

5-HTP in Patients With IBD in Clinical and Biologic Remission:Effect on Fatigue Scores (TRP-IBD)

Fatigue | Crohn Disease | Ulcerative Colitis | Remission

Belgium
Qiang Fu
Yangtze River Pharmaceutical Group Co., Ltd.

Not yet recruiting

Cancer-related Fatigue in Patients With Breast Cancer Treatment With Zhengyuan Capsules (CRF)

Cancer-related Fatigue
University of California, San Diego
Pfizer

Completed

Ramipril for the Treatment of COVID-19 (RAMIC)

COVID-19

United States
Indonesia University

Completed

Melatonin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response in Locally Advanced Oral Squamous Cell Carcinoma

Oral Squamous Cell Carcinoma | Neoadjuvant Chemotherapy

Indonesia
Hospital de Clinicas de Porto Alegre

Completed

Melatonin as a Circadian Clock Regulator, Neuromodulator and Myelo-protector in Adjuvant Breast Cancer Chemotherapy

Depression | Pain | Sleep Disorders, Circadian Rhythm | Genotoxicity
Genentech, Inc.

Completed

A Study of the Hedgehog Pathway Inhibitor GDC-0449 in Healthy Female Subjects of Non-Childbearing Potential

Healthy
Birmingham Community Healthcare NHS
NSA, LLC

Completed

Effect of Dietary Intake of Dried Whole Food Concentrates (Juice Plus) on Clinical Outcomes Following Periodontal Therapy: A Pilot Study (BHAM-NSA-05-01)

Periodontitis

United Kingdom
PETHEMA Foundation

Active, not recruiting

Protocol GELLC-7: Ibrutinib Followed by Ibrutinib Consolidation in Combination With Ofatumumab

Chronic Lymphocytic Leukemia

Spain
Peking Union Medical College Hospital

Unknown

Efficacy and Safety Study of Anlotinib With Pembrolizumab in Adults With Programmed Cell Death-Ligand 1 (PD-L1)-Positive Treatment-naïve Non-small Cell Lung Cancer

NSCLC

China
Sandoz

Completed

Relative Bioavailability Study of Ribavirin 200 Capsules and Rebetol 200 mg Capsules in Females Under Fasting Conditions

Chronic Hepatitis C
AstraZeneca

Withdrawn

A Study to Compare the Pharmacokinetics of Different Formulations of AZD9977 and the Influence of Food in Healthy Male Subjects

Healthy Male Subjects | Pharmacokinetics | Safety | Food Effect

United Kingdom
Isfahan University of Medical Sciences

Unknown

Vitamin D Deficiency Treatment Outcomes After Non-ST-Segment Elevation Myocardial Infarction (NAVID)

Inflammation | Vitamin D Deficiency | Coronary Artery Disease With Myocardial Infarction | Non-ST Elevation Myocardial Infarction (nSTEMI)

Iran, Islamic Republic of
NovaBiotics Ltd.
Agility Clinical, Inc.; PSR Group B.V.

Completed

A Study of the Dosing, Efficacy, and Safety of Oral Cysteamine in Adult Patients With Cystic Fibrosis Exacerbations (CARE-CF1)

Cystic Fibrosis

United States, United Kingdom, Italy
Melinda Telli
Pfizer; BioMarin Pharmaceutical

Completed

Phase II Trial of Talazoparib in BRCA1/2 Wild-type HER2-negative Breast Cancer and Other Solid Tumors

Advanced Breast Cancer | HER2/Neu Negative | Triple-Negative Breast Cancer

United States
Pfizer
Medivation, Inc.; Myriad Genetic Laboratories, Inc.

Terminated

A Phase 2, 2-Stage, 2-Cohort Study of Talazoparib (BMN 673), in Locally Advanced and/or Metastatic Breast Cancer Patients With BRCA Mutation (ABRAZO Study) (ABRAZO)

Breast Neoplasms | BRCA 1 Gene Mutation | BRCA 2 Gene Mutation

United States, Spain, United Kingdom, Germany, France
Massimo Raimondo, M.D.
Digestive Care, Inc.

Terminated

PERT for Treatment of Exocrine Pancreatic Insufficiency in Patients With Unresectable Pancreatic Cancer

Pancreatic Cancer | Pancreatic Insufficiency | Pancreatic Enzyme Abnormality

United States
Rabin Medical Center
Rambam Health Care Campus; Hillel Yaffe Medical Center; US Department of Veterans... and other collaborators

Completed

Capsule Endoscopy Crohn's Disease Activity Index - Validation Multi Center Study

Crohn's Disease

Israel, Ireland

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