Clinical Trials Sponsored by Cambridge University Hospitals NHS (National Health Service) Foundation Trust

Total 671 results

CCTU- Cancer Theme
AstraZeneca

Recruiting

AZD6738 & Gemcitabine as Combination Therapy (ATRiUM)

Cancer

United Kingdom
CCTU- Cancer Theme
AstraZeneca

Unknown

Cambridge Liquid Biopsy and Tumour Profiling Study for Patients on Experimental Therapeutics Trials (CALIBRATE)

Cancer

United Kingdom
CCTU- Cancer Theme
Celgene

Completed

Scheduling Nab-paclitaxel With Gemcitabine (SIEGE)

Pancreatic Adenocarcinoma Metastatic

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Vifor Pharma; Aspreva Pharmaceuticals

Completed

Clinical Trial of Mycophenolate Versus Cyclophosphamide in ANCA Vasculitis (MYCYC)

Vasculitis

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
King's College Hospital NHS Trust; Cambridge University Hospitals NHS Foundation... and other collaborators

Completed

The REPOSE (Relative Effectiveness of Pumps Over MDI and Structured Education) Trial (REPOSE)

Type 1 Diabetes

United Kingdom
Dr Ian B Wilkinson

Recruiting

Screening for Primary Aldosteronism in Hypertension With 24-hour URinary aLdosterone (PURL)

Hypertension | Primary Aldosteronism | Urine Aldosterone

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
AstraZeneca; Cancer Research UK

Recruiting

Platinum and Polyadenosine 5'Diphosphoribose Polymerisation Inhibitor for Neoadjuvant Treatment of Triple Negative Breast Cancer and/or Germline BRCA Positive Breast Cancer (PARTNER)

Breast Cancer

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Rigshospitalet, Denmark; Birmingham Women's and Children's NHS Foundation Trust and other collaborators

Unknown

Effect of Insulin Sensitization on IGF-1 Response to Growth Hormone in SGA Children

Small for Gestational Age
Cambridge University Hospitals NHS Foundation Trust
University of East Anglia; Manchester University NHS Foundation Trust; National...

Not yet recruiting

Co-designing and Evaluating a Real-world Implementation Model for Remote Consultation With Vision Self-testing. (ReVise)

Ophthalmic Disorders
University of Cambridge
Imperial College London; Cambridge University Hospitals NHS Foundation Trust; Wellcome Trust and other collaborators

Active, not recruiting

PET Imaging of Giant Cell and Takayasu Arteritis (PITA)

Giant Cell Arteritis | Takayasu Arteritis

United Kingdom
Ourotech, Inc.
Royal Free Hospital NHS Foundation Trust; Imperial College Healthcare NHS Trust and other collaborators

Not yet recruiting

Prospective Evaluation of AI R&D Tool for Patient Stratification: a Trial for Renal Immuno-oncology Model Experimental Evaluation 2 (PEAR-TREE2)

Kidney Cancer | Renal Cell Cancer Metastatic

United Kingdom
King's College London
King's College Hospital NHS Trust; University College London Hospitals; Cambridge... and other collaborators

Recruiting

The Clinical Impact of the Basophil Activation Test to Diagnose Food Allergy

Egg Allergy | Food Allergy | Food Allergy in Children | Milk Allergy | Food Allergy in Infants | Nut Allergy | Food Allergen Sensitisation

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Norfolk and Norwich University Hospitals NHS Foundation Trust; Luton and Dunstable... and other collaborators

Recruiting

EAGLET: EEG vs aEEG to Improve the Diagnosis of neonataL Seizures and Epilepsy (EAGLET)

Neonatal Seizures

United Kingdom
CCTU- Cancer Theme
Cambridge Cellular Therapies Laboratory; The Evelyn Trust

Unknown

A Study to Collect Bone Marrow for Process Development and Production of BM-MSC to Treat Severe COVID19 Pneumonitis (COMET20d)

Healthy Volunteers for Bone Marrow Donation

United Kingdom
The Leeds Teaching Hospitals NHS Trust
Cambridge University Hospitals NHS Foundation Trust; Nottingham University... and other collaborators

Completed

Hospital Onset Diarrhoea Investigation (HOODINI)

Diarrhea

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Oxford; National Institute for Health Research, United Kingdom; Oxford University Hospitals NHS Trust

Completed

Continuous vs Intermittent Dabrafenib Plus Trametinib in BRAFV600 Mutant Stage 3 Unresectable or Metastatic Melanoma (INTERIM)

Melanoma

United Kingdom
CCTU- Cancer Theme
University of Cambridge; Microsoft Research

Recruiting

Heuristics, Algorithms and Machine Learning: Evaluation & Testing in Radiation Therapy (Hamlet rt)

Cancer

United Kingdom
University of Oxford
Oxford University Hospitals NHS Trust; South Central Ambulance Service NHS... and other collaborators

Completed

Computer Assisted Lessening of Intrusive Memories in the Emergency Department (CALM-ED)

Post Traumatic Stress Disorder

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Cambridge University Hospitals NHS Foundation...

Completed

Quantification of Breast RadioTherapy Associated Late Toxicity Using Novel UltraSound Techniques (QuaRTUS)

Breast Radiotherapy Toxicity

United Kingdom
University of Cambridge
Medical University of Graz; University Hospital Birmingham NHS Foundation Trust and other collaborators

Completed

24/7 Closed-loop in Older Subjects With Type 1 Diabetes (DAN06)

Hypoglycemia | Type 1 Diabetes Mellitus | Arrythmia

United Kingdom
Imperial College London
King's College Hospital NHS Trust; University College London Hospitals; Cambridge... and other collaborators

Active, not recruiting

National Institute for Health Research (NIHR) Health Informatics Collaborative Troponin Study (NHIC-Troponin)

Mortality | Acute Coronary Syndrome | Troponin | Age
Pneumacare Ltd
Cambridge University Hospitals NHS Foundation Trust; University Hospitals of... and other collaborators

Completed

Validation of Structured Light Plethysmography: Asthma (SLPBD)

Asthma

United Kingdom
University Hospital Plymouth NHS Trust
Université de Sherbrooke; Erasmus Medical Center; Cambridge University Hospitals... and other collaborators

Enrolling by invitation

Defining Core Outcomes and Data Elements (CODE) in Chronic Subdural Haematoma (CODE-CSDH)

Chronic Subdural Hematoma

United Kingdom
University of Oxford
King's College Hospital NHS Trust; Nottingham University Hospitals NHS Trust; Guy's and St Thomas' NHS Foundation Trust and other collaborators

Enrolling by invitation

Echocardiography: Value and Accuracy at REst and STress (EVAREST)

Coronary Artery Disease | Angina Pectoris | Ischaemic Heart Disease
Shruti Agrawal
Action Medical Research

Recruiting

Studying Trends of Auto-Regulation in Severe Head Injury in Paediatrics (STARSHIP)

TBI (Traumatic Brain Injury)

United Kingdom
University of Cambridge
Cambridgeshire and Peterborough NHS Foundation Trust; Cambridge Cognition Ltd; Big Health Inc...

Completed

CBT to Reduce Insomnia and Improve Social Recovery in Early Psychosis (CRISP)

Psychotic Disorders | Sleep | Psychosis

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Juvenile Diabetes Research Foundation; Wellcome Trust; University of Cambridge; National Institute for Health Research, United Kingdom and other collaborators

Completed

Adaptive Study of IL-2 Dose Frequency on Regulatory T Cells in Type 1 Diabetes (DILfrequency)

Type 1 Diabetes

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University College London Hospitals; Cambridge University Hospitals NHS Foundation... and other collaborators

Completed

Alternative Delivery of Dose Adjustment For Normal Eating (DAFNE) Trial in Patients With Type 1 Diabetes

Type 1 Diabetes Mellitus

United Kingdom
CCTU- Cancer Theme
Microbiotica Ltd

Recruiting

Microbiome Immunotherapy Toxicity and Response Evaluation

Melanoma | Lung Cancer | Renal Cancer

United Kingdom
Simon C Pacey, MD
AstraZeneca

Active, not recruiting

Do Changes in ctDNA Predict Response for Patients With Oesophageal Cancer Receiving Durvalumab (CALIBRATION)

Oesophageal Cancer

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge; Medical Research Council Mitochondrial Biology Unit

Completed

Nicotinamide Riboside and Mitochondrial Biogenesis

Mitochondrial Diseases | Mitochondrial Myopathies | Progressive External Ophthalmoplegia | Progressive Ophthalmoplegia | Progressive; Ophthalmoplegia, External | Mitochondria DNA Deletion | MELAS

United Kingdom
Owlstone Ltd
Cambridge University Hospitals NHS Foundation Trust; Cancer Research UK

Completed

PAN-study: Pan-Cancer Early Detection Study (PAN)

Gastric Cancer | Esophageal Cancer | Liver Cancer

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust; Institute of Cancer Research...

Completed

Primary Thrombocythaemia 1 Trial (PT-1)

Myeloproliferative Disorder | Thrombocythemia

United Kingdom
University of Manchester
Manchester University NHS Foundation Trust; Hull University Teaching Hospitals... and other collaborators

Completed

Saving Babies' Lives Project Impact and Results Evaluation: a Mixed Methodology Study (SPiRE)

Stillbirth

United Kingdom
University College, London
The Leeds Teaching Hospitals NHS Trust; Cambridge University Hospitals NHS... and other collaborators

Unknown

Ketogenic Diet in Infants With Epilepsy (KIWE) (KIWE)

Epilepsy

United Kingdom
University of Cambridge
Guy's and St Thomas' NHS Foundation Trust; Manchester University NHS Foundation... and other collaborators

Completed

Observational Cohort Study of a National Extracorporeal Membrane Oxygenation Service for Adults With Respiratory Failure: the NHS ECMO Study. (NHS ECMO)

Acute Respiratory Failure
University of Nottingham
Northern Care Alliance NHS Foundation Trust; Cambridge University Hospitals... and other collaborators

Recruiting

Pseudo-obstruction Assessment With MRI (POM)

Chronic Intestinal Pseudo-Obstruction

United Kingdom
Papworth Hospital NHS Foundation Trust
Cancer Research UK; University of Cambridge

Recruiting

Second Primary Lung Cancer Cohort Study (SPORT) (SPORT)

Lung Cancer

United Kingdom
Papworth Hospital NHS Foundation Trust
Medical Research Council; University of Cambridge

Completed

StratosPHere (Non-interventional Study)

Pulmonary Arterial Hypertension | Pulmonary Hypertension | Idiopathic Pulmonary Arterial Hypertension | Respiratory Disease

United Kingdom
University Hospital Southampton NHS Foundation...
Royal Marsden NHS Foundation Trust; University College London Hospitals; Cambridge... and other collaborators

Unknown

Coronavirus Infection in Primary or Secondary Immunosuppressed Children and Adults. (ImmunoCOVID)

COVID | Infection | Immune Deficiency | Immune Suppression | Children, Adult

United Kingdom
Queen's University, Belfast
The Leeds Teaching Hospitals NHS Trust; Cambridge University Hospitals NHS... and other collaborators

Recruiting

Co-morbidity and Refractory Asthma - UK Severe Asthma Registry (UKSAR)

Asthma

United Kingdom
University of Edinburgh
Royal Free Hospital NHS Foundation Trust; National Health Service, United Kingdom

Active, not recruiting

The Effect of Varying Brightness on Palpebral Aperture

Eyelid Ptoses

United Kingdom
University Hospital Southampton NHS Foundation...
University of Southampton; University of Cambridge

Not yet recruiting

Mitochondrial Function in the Peri-operative Setting: an Observational Study (MITOSIS)

Perioperative Complication | Surgery-Complications | Mitochondrial

United Kingdom
University College, London
University College London Hospitals; Cambridge University Hospitals NHS Foundation...

Completed

Listen in: Developing and Testing a Therapy Application for Patients With Speech Comprehension Deficits After Stroke. (Listen-in)

Aphasia

United Kingdom
University Hospital Southampton NHS Foundation...
The Leeds Teaching Hospitals NHS Trust; University of Southampton; Newcastle-upon-Tyne... and other collaborators

Recruiting

Reconstruction in Extended MArgin Cancer Surgery (REMACS)

Quality of Life | Surgery--Complications | Abdominal Cancer | Pelvic Cancer

United Kingdom
CCTU- Cancer Theme
Breast Cancer Now; CRUK Cambridge Institute

Recruiting

Neo-RT: A Study Investigating Whether Changing the Sequence of Treatments (Starting Radiotherapy Followed by Hormone Therapy Before Surgery) is Feasible (Neo-RT)

Breast Cancer

United Kingdom
Portsmouth Hospitals NHS Trust
King's College Hospital NHS Trust; University College London Hospitals; Northern... and other collaborators

Completed

A Evaluation of the Utilisation, Effectiveness and Safety of Purastat® in the Management of Gastrointestinal Bleeding (POPS)

Gastrointestinal Bleeding

United Kingdom
Royal United Hospitals Bath NHS Foundation Trust
Sheffield Teaching Hospitals NHS Foundation Trust; Royal Free Hospital NHS... and other collaborators

Not yet recruiting

Developing the Probability Algorithm for Pulmonary Hypertension Echocardiography (DRAPE)

Pulmonary Hypertension

United Kingdom
Weill Medical College of Cornell University
Cambridge University Hospitals NHS Foundation Trust

Terminated

To Assess the Safety of Continuous IV Administration of Plerixafor and Assess Impact on the Immune Microenvironment in Patients With Pancreatic, Ovarian and Colorectal Adenocarcinomas

Pancreas Cancer

United States, United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Imperial College London; University of Manchester

Unknown

The Effect of Extrinsic Factors on Food Allergy (Ex-Factor)

Peanut Hypersensitivity

United Kingdom

Clinical Trials Sponsored by Cambridge University Hospitals NHS (National Health Service) Foundation Trust

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Myanmar

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations