Hospital Onset Diarrhoea Investigation

National Infection Trainees Collaborative for Audit and Research (NITCAR) Service Evaluation: The Prevalence, Aetiology and Management of Hospital-onset Diarrhoea on Medical, Surgical and Elderly Care Wards in the NHS

Sponsors

Lead Sponsor: The Leeds Teaching Hospitals NHS Trust

Collaborator: Aneurin Bevan University Health Board
Northern Health and Social Care Trust
Barnsley Hospital NHS Foundation Trust
Cambridge University Hospitals NHS Foundation Trust
East Lancashire Hospitals NHS Trust
Guy's and St Thomas' NHS Foundation Trust
Hampshire Hospitals NHS Foundation Trust
Harrogate & District NHS Foundation Trust
Hull University Teaching Hospitals NHS Trust
Mid Yorkshire Hospitals NHS Trust
NHS Greater Glasgow and Clyde
NHS Lothian
Nottingham University Hospitals NHS Trust
Oxford University Hospitals NHS Trust
Papworth Hospital NHS Foundation Trust
Sheffield Teaching Hospitals NHS Foundation Trust
South Tees Hospitals NHS Foundation Trust
Royal Free Hospital NHS Foundation Trust
The Royal Wolverhampton Hospitals NHS Trust
Torbay and South Devon NHS Foundation Trust
South Eastern Health and Social Care Trust
University Hospitals Coventry and Warwickshire NHS Trust
George Eliot Hospital NHS Trust
University Hospitals, Leicester
York Teaching Hospitals NHS Foundation Trust

Source The Leeds Teaching Hospitals NHS Trust
Brief Summary

This service evaulation aims to investigate how common diarrhoea is in hospital patients on medical, surgical and elderly care wards, what it is due to and how it is managed.

Detailed Description

Latest National Health Service (NHS) England guidelines for the assessment of Clostridium difficile infection (CDI) cases recommend that acute hospitals collect data on the prevalence of hospital-onset diarrhoea in their organisations, and how it is managed, including if patients are appropriately tested for CDI. The aims of this multi-centre service evaluation are therefore to: - Determine the prevalence of hospital-onset diarrhoea on adult medical, surgical and care of the elderly wards in the NHS - Investigate how hospital-onset diarrhoea is managed, including whether patients are tested for CDI according to Department of Health (DoH) England standards - Investigate the aetiology of hospital-onset diarrhoea on adult medical, surgical and care of the elderly wards in the NHS, based on previously described causes Data will be collected at participating centres on two days, one between 11-15/Jan/2016 and one between 6-10/Jun/2016. Hospitals will be able to choose locally which two days. On those days investigators from the local Microbiology and/or Infection Prevention teams will screen all patients on pre-identified wards, who have been admitted for ≥72 hours, for hospital-onset diarrhoea. For all patients that meet the definition of hospital-onset diarrhoea their medical notes and charts will be reviewed, to ascertain potential causes and how they have been managed. This service evaluation should help participating hospitals to investigate hospital-onset diarrhoea in their own institutions, as well as generating a dataset that is representative of the problem across the NHS, and therefore of use to other centres.

Overall Status Completed
Start Date 2016-01-01
Completion Date 2016-08-01
Primary Completion Date 2016-06-01
Study Type Observational
Primary Outcome
Measure Time Frame
Point-prevalence of hospital-onset diarrhoea At enrollment
Secondary Outcome
Measure Time Frame
• The proportion of patients with hospital-onset diarrhoea who have been assessed for the problem by a member of the clinical team. At enrollment
• The proportion of patients with hospital-onset diarrhoea that are tested for CDI (both overall and amongst those who do and do not have an alternative explanation for the diarrhoea). Up to 72 hours after enrollment
Enrollment 230
Condition
Eligibility

Sampling Method:

Non-Probability Sample

Criteria:

Inclusion Criteria: - Admitted to hospital for ≥72 hours at the time of data collection for the service evaluation - Presence of hospital-onset diarrhoea (defined as ≥ 2 episodes of unformed stools (Bristol Stool Chart type 5-7) during the day before the service evaluation, with the onset of the diarrhoea being more than 48 hours after admission to hospital) Exclusion Criteria: - Patients admitted to the ward for ≤72hour at the time of data collection for the service evaluation - Patients with diarrhoea since admission or in whom it developed within the first 48 hours of admission - Patients receiving end of life care

Gender:

All

Minimum Age:

16 Years

Maximum Age:

N/A

Healthy Volunteers:

No

Overall Official
Location
Facility:
Antrim Area Hospital (Northern Health and Social Care Trust) | Antrim, United Kingdom
Barnsley Hospital NHS Foundation Trust | Barnsley, United Kingdom
East Lancashire Hospitals NHS Trust | Blackburn, United Kingdom
Cambridge University Hospitals NHS Foundation Trust | Cambridge, United Kingdom
University Hospitals Coventry and Warwickshire + George Eliot Hospital NHS Trust | Coventry, United Kingdom
Ulster Hospital (South Eastern Health and Social Care Trust) | Dundonald, United Kingdom
NHS Lothian and NHS Fife | Edinburgh, United Kingdom
NHS Greater Glasgow and Clyde | Glasgow, United Kingdom
Harrogate and District NHS Foundation Trust | Harrogate, United Kingdom
Hull and East Yorkshire Hospitals NHS Trust | Hull, United Kingdom
University Hospitals of Leicester NHS Trust | Leicester, United Kingdom
Guy's & St Thomas' NHS Foundation Trust | London, United Kingdom
The Royal Free London NHS Foundation Trust | London, United Kingdom
South Tees Hospitals NHS Foundation Trust | Middlesborough, United Kingdom
Aneurin Bevan University Health Board | Newport, United Kingdom
Nottingham University Hospitals NHS Trust | Nottingham, United Kingdom
Oxford University Hospitals NHS Trust | Oxford, United Kingdom
Papworth Hospital NHS Foundation Trust | Papworth, United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust | Sheffield, United Kingdom
Torbay and South Devon Healthcare NHS Foundation Trust | Torbay, United Kingdom
Mid Yorkshire NHS Trust | Wakefield, United Kingdom
Hampshire Hospitals NHS Foundation Trust | Winchester, United Kingdom
The Royal Wolverhampton NHS Trust | Wolverhampton, United Kingdom
York Teaching Hospital NHS Foundation Trust | York, United Kingdom
Location Countries

United Kingdom

Verification Date

2017-10-01

Responsible Party

Type: Sponsor

Keywords
Has Expanded Access No
Condition Browse
Acronym HOODINI
Patient Data No
Study Design Info

Observational Model: Case-Only

Time Perspective: Cross-Sectional

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