Clinical Trials Sponsored by Emergent BioSolutions

Total 666 results

Emergex Vaccines Holding Ltd.

Not yet recruiting

Next Generation T-cell Vaccine Against Coronavirus Disease (COVID-19)

COVID-19 | Coronavirus | SARS-CoV-2 Infection

Philippines
Herlev Hospital
Hvidovre, Amager and Glostrup Hospital, Department of Emergency Medicine; Bispebjerg... and other collaborators

Completed

Implementation of the Individual Danish Emergency Process Triage (I-DEPT)

Emergencies | Acute Disease | Clinical Syndrome

Denmark
Institute of Mountain Emergency Medicine

Not yet recruiting

Accuracy of Core Body Temperature Measurement Depending on Oesophageal Probe Tip Location (ESO-TIP)

Emergencies | Hypothermia
Sklifosovsky Institute of Emergency Care

Recruiting

General Anesthesia Versus Awake Surgery in Resection of Gliomas and Metastases of Motor Areas (GAMMA)

Glioma, Malignant | Gliomas Benign | Metastases to Brain

Russian Federation
Sklifosovsky Institute of Emergency Care

Recruiting

Intraoperative Brain Shift Calculation Study (BRASH)

Arteriovenous Malformations | Tumor, Brain | Cavernoma | Intracerebral Hematoma

Russian Federation
Sklifosovsky Institute of Emergency Care

Recruiting

Intraoperative Sonographically Versus Fluorescence-guided Resection of Contrast-enhancing Gliomas and Brain Metastases (SONOFLUO)

Metastases to Brain | Gliomas, Malignant

Russian Federation
Sklifosovsky Institute of Emergency Care

Recruiting

Intraoperative Sonographically Guided Resection of Non-enhancing Gliomas (SONOGLIO)

Non-enhancing Cerebral Gliomas

Russian Federation
World Society of Emergency Surgery

Completed

Physiologic Indicators for Prognosis in Abdominal Sepsis Study (PIPAS)

Abdominal Sepsis | Acute Peritonitis

Italy
ANRS, Emerging Infectious Diseases
Pfizer

Completed

Immuno-stimulation With Maraviroc Combined to Antiretroviral Therapy in Advanced Late Diagnosed HIV-1 Infected Patients (OPTIMAL)

HIV-1 Infection | AIDS

France
Loredana Ghinea

Unknown

Morphine Versus Ketorolac in Low Back Pain

Low Back Pain
Institute of Mountain Emergency Medicine

Completed

Suspension Syndrome

Orthostatic Hypotension | Circulatory Failure | Syncope, Vasovagal, Neurally-Mediated | Circulatory Collapse
ANRS, Emerging Infectious Diseases
Abbott

Completed

Prevention of HIV1 Mother to Child Transmission Without Nucleoside Analogue Reverse Transcriptase Inhibitors in the Pre-partum Phase. ANRS 135 Primeva

HIV Infections

France
Institute of Mountain Emergency Medicine

Not yet recruiting

Comparison of Three Pre-oxygenation Strategies

Emergencies | Anesthesia
Sklifosovsky Institute of Emergency Care

Recruiting

Effectiveness of Conservative Treatment in Patients With Thoracic and Lumbar Fractures Without Neurological Deficit

Spine Fusion | Spine Fracture | Thoracic Spine Fracture | Thoracolumbar Burst Fracture | Lumbar; Spine, Fracture | Fracture of Spine, Level Unspecified

Russian Federation
Sklifosovsky Institute of Emergency Care

Recruiting

Functional Navigation in Surgery of Cerebral Tumors and Vascular Malformations (FUN)

Arteriovenous Malformations | Tumor, Brain | Cavernoma

Russian Federation
Institute of Mountain Emergency Medicine

Completed

Effect of Wearing Personal Protective Equipment (PPE) on CPR Quality in Times of the COVID-19-pandemic

Cardiopulmonary Resuscitation | Personal Protective Equipment

Italy
Northwestern University
Emergency Medicine Foundation

Completed

Prescribing Opioid Pain Relievers in the Emergency Department: Understanding and Optimizing the Encounter

Opioid Use, Unspecified

United States
Institute of Mountain Emergency Medicine

Completed

Implementation of LUCAS 2 in Helicopter Rescue in South Tyrol

Cardiac Arrest

Italy
World Society of Emergency Surgery

Unknown

Italian Register for the Study of Complicated Intra-Abdominal Infections (IRCA)

Complicated Intra-abdominal Infections

Italy
Loredana Ghinea

Unknown

Morphine Versus Ketorolac in Renal Colic

Renal Colic
Florin Iordache

Completed

Peritoneal Bacterial Contamination Following Resection With Closed or Open Rectal Stump for Left-sided Cancer

Bacterium-Related Malignant Neoplasm
ANRS, Emerging Infectious Diseases
Pfizer

Completed

Efficacy and Safety of Varenicline Among HIV-infected Patients (Inter-ACTIV)

HIV Infections | Tobacco Dependence

France
Institute of Mountain Emergency Medicine

Completed

The Incidence of Subclinical High-altitude Pulmonary Oedema at High Altitude

Acute Mountain Sickness | Subclinical High Altitude Pulmonary Edema

Italy
ANRS, Emerging Infectious Diseases
Gilead Sciences

Not yet recruiting

A Study to Determine the Cartography of Virologic Reservoir Related to Antiretroviral Concentrations in HIV-1 Chronic Patients Treated by a First Line Treatment Containing bictégravir, Emtricitabine and ténofovir alafénamide

HIV-1-infection

France
NYU Langone Health
Emergency Medicine Foundation

Completed

Buprenorphine Loading in the Emergency Department

Opioid-use Disorder

United States
University of Pennsylvania
Emergency Medicine Foundation

Active, not recruiting

Identifying Mental Health Distress in EM Physicians

Burnout, Professional

United States
Iacob Czihac Emergency Military Clinical Hospital

Completed

Risk Factor Involved in Knee Osteoarthritis (KOA)

Knee Osteoarthritis

Romania
David Peran

Enrolling by invitation

Causes of Traffic Collisions of Ambulance Cars at the Prague Emergency Medical Services

Traffic Collision | Transport Accident

Czechia
Emergency Medical Services, Capital Region, Denmark

Completed

Machine Learning Assisted Recognition of Out-of-Hospital Cardiac Arrest During Emergency Calls.

Out-Of-Hospital Cardiac Arrest

Denmark
ANRS, Emerging Infectious Diseases
ViiV Healthcare

Completed

A Trial Evaluating Maintenance Therapy With Lamivudine (Epivir®) and Dolutegravir (Tivicay®) in Human Immunodeficiency Virus 1 (HIV-1) Infected Patients Virologically Suppressed With Triple Highly Active Antiretroviral Therapy (HAART) (ANRS 167 Lamidol)

HIV-1 Infection

France
ANRS, Emerging Infectious Diseases
Janssen Pharmaceuticals

Completed

Evaluation of a Maintenance Strategy With Protease Inhibitors With or Without Lamivudine in Virologically Suppressed HIV Patients on Second Line Antiretroviral Treatment in Africa (MOBIDIP)

HIV Infection

Cameroon, Burkina Faso, Senegal
University of Monastir
Emergency NGO Onlus

Completed

Acupuncture Versus IV Morphine in the Treatment of Acute Pain in ED (AcuMoPE)

Renal Colic

Tunisia
59th Medical Wing
Emergency Medicine Foundation

Completed

Prospective Randomized Trial of Bactrim on 7 Day Outcome in Patients With Uncomplicated Abscesses

Abscesses

United States
Peking University People's Hospital
Beijing Emergency Medical Center; Beijing Red Cross Emergency Center

Completed

Trends of the Pre-hospital Emergency Care Spectrum in Beijing From 2005 to 2014: A Retrospective Analysis

Emergencies [Disease/Finding]

China
Pediatric Clinical Research Platform
Geneva Emergency Medical Services, Geneva, Switzerland; Lausanne Emergency... and other collaborators

Completed

Reducing Prehospital Medication Errors & Time to Drug Delivery by EMS During Simulated Pediatric CPR

Emergency Medical Services | Pediatrics | Resuscitation | Cardiopulmonary Arrest | Medication Errors

Switzerland
Academisch Medisch Centrum - Universiteit van Amsterdam...
Erasmus Medical Center; Prothya Biosolutions

Recruiting

DUPIlumab Dose REDUCtion in Patients With Controlled Atopic Eczema (DUPI REDUCE)

Atopic Dermatitis | Atopic Dermatitis Eczema

Netherlands
ANRS, Emerging Infectious Diseases
MSD France

Not yet recruiting

DORAvirine Versus DOlutegravir Based Antiretroviral Regimens in Treatment-naïve People Living With HIV-1 Infection (ELDORADO)

HIV-1-infection

Brazil, Cambodia, Cameroon, Côte D'Ivoire, France, Mozambique
Yang Jing

Not yet recruiting

Clonal Hematopoiesis on Prognosis in Patients With Myocardial Infarction

To Investigate the Effect of CHIP on Renal Insufficiency in AMI Patients
Emergency Medical Services, Capital Region, Denmark

Enrolling by invitation

Does Bystanders Emotional State Influence Dispatcher-assisted Cardiopulmonary?Resuscitation

Emotional Distress | Out-Of-Hospital Cardiac Arrest

Denmark
ANRS, Emerging Infectious Diseases
Institut Pasteur

Unknown

"Real Life" Evaluation of Efficacy and Safety of Direct Antiviral Agents (DAAs) for the Treatment of Hepatitis C Virus in Egypt (HepNile)

Chronic Hepatitis C

Egypt
University of Florida
Emergency Medicine Foundation

Completed

Implementing an Emergency Department to Home Care Transition Intervention

ED Patients With Chronic Medical Illnesses

United States
ANRS, Emerging Infectious Diseases
Flamel Technologies

Unknown

Study Comparing the Tolerability and Viral Reduction of the Combination of IFN a-2b XL + Ribavirin Versus Peg IFN a-2b + Ribavirin in Patients With Chronic Hepatitis C, Genotype 1 or 4 (COAT IFN)

Chronic Hepatitis C

France
Advocate Hospital System
Emergency Medicine Foundation

Completed

The Effect of Etomidate on Patient Outcomes After Single Bolus Doses

Sepsis | Trauma

United States
David Peran

Not yet recruiting

Standardization of Ambulance Equipment

Safety Issues

Czechia
ANRS, Emerging Infectious Diseases
Mylan Laboratories

Active, not recruiting

ANRS 12372 MODERATO Study (MODERATO)

HIV-1-infection

Côte D'Ivoire, Burkina Faso, Cameroon
ANRS, Emerging Infectious Diseases
ViiV Healthcare

Completed

Cartography of Virologic Reservoir Related to Antiretroviral Concentrations in HIV-1 Chronic Patients Treated by a First Line Treatment Containing Dolutegravir and Associated Nucleoside / Nucleotide Reverse Transcriptase Inhibitors Backbone (DOLUVOIR)

HIV-1 Infection

France
University of Monastir
Emergency NGO Onlus

Completed

Intensive Arterial Pressure Control in Acute Coronary Syndrome (IAPREC)

Acute Coronary Syndrome

Tunisia
County Clinical Emergency Hospital Cluj-Napoca

Completed

Imaging-based, Non-invasive Diagnosis of Persistent Atrial Fibrillation (imATFIB)

Atrial Fibrillation

Romania
ANRS, Emerging Infectious Diseases
Institut Pasteur

Withdrawn

Efficacy and Safety of the Combination Vitamin D With Standard of Care in Egyptian Patients With Untreated Chronic Hepatitis C (ViZIR)

Chronic Hepatitis C

Egypt
RenJi Hospital
Shanghai Pudong Emergency Center

Unknown

Pre-hospital Administration of Tranexamic Acid for Moderate and Severe Traumatic Brain Injury

Brain Injuries, Traumatic

China

Clinical Trials Sponsored by Emergent BioSolutions

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