Clinical Trials Sponsored by Merck KGaA

Total 5035 results

Merck KGaA, Darmstadt, Germany
Merck, S.L., Spain

Completed

Growth Hormone in Neuroendocrine Dysfunction With Severe Fibromyalgia Syndrome

Fibromyalgia

Spain
Merck KGaA, Darmstadt, Germany
Merck, S.L., Spain

Completed

Follow-up to Adult Height of a Cohort of Subjects Born Small for the Gestational Age and Treated With Growth Hormone (SGA)

Infant, Small for Gestational Age

Spain
Merck KGaA, Darmstadt, Germany
Merck, S.L., Spain

Completed

To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in Spain (ECOS ESP)

Growth Disorders

Spain
Merck KGaA, Darmstadt, Germany
Merck Ltd., India

Terminated

An Observational Study to Evaluate the Safety and Efficacy of Cetuximab in Combination With Platinum-based Chemotherapy in the First-line Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck

Carcinoma, Squamous Cell

India
Merck KGaA, Darmstadt, Germany
Merck Ltd., Thailand

Terminated

Glucophage XR® Observational Study

Diabetes Mellitus Type 2 | GI Side Effect

Thailand
Merck KGaA, Darmstadt, Germany
Merck, S.L., Spain

Withdrawn

Evaluate Adherence to Treatment With Glucophage Sachets Versus Tablets in Diabetes Type 2 Patients Previously Treated With Metformin Tablets

Diabetes Mellitus Type 2
Pfizer
Merck KGaA, Darmstadt, Germany

Active, not recruiting

A NON-INTERVENTIONAL STUDY ON AVELUMAB USE IN PATIENTS WITH ADVANCED OR METASTATIC UROTHELIAL CARCINOMA (AVENANCE)

Urothelial Carcinoma

France
Merck KGaA, Darmstadt, Germany
Pfizer

Approved for marketing

Expanded Access to Avelumab for Treatment of Metastatic Merkel Cell Carcinoma (mMCC)

Metastatic Merkel Cell Carcinoma

France
Sanofi
Merck KGaA, Darmstadt, Germany

Completed

A Safety and Efficacy Study of SAR405838 and Pimasertib in Cancer Patients

Neoplasm Malignant

Netherlands, France
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

JAVEMACS: Japan AVElumab Maintenance And Continuous Treatment Study

Urothelial Carcinoma

Japan
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

M1774 Human Mass Balance Study (DDRIVER Solid Tumors 303)

Solid Tumor

Hungary
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

Cladribine Tablets Level of Response Predictors in Clinical Practice (CLODINA)

Multiple Sclerosis

Greece, Czechia, Portugal, Belgium, Netherlands, Poland
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

Phase IIa Proof of Concept Study of M5717-Pyronaridine in Adults and Adolescents With Acute Uncomplicated Plasmodium Falciparum Malaria (CAPTURE 1)

Acute Malaria

Burkina Faso, Gabon, Mozambique, Uganda
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Cognition and HRQoL in Adults With Highly-active RMS in Year 3 and 4 After Initial Mavenclad® Dose (CLARIFY MS Extension)

Multiple Sclerosis

Spain, France, Czechia, Slovakia, Italy, Hungary, Austria, Denmark, Netherlands, Poland
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Extension to the MAGNIFY MS Trial on Mavenclad® (Magnify MS Extension)

Multiple Sclerosis

United Kingdom, Germany, Finland, Israel, Spain, Canada, France, Australia, Czechia, Austria, Sweden, Poland, Hungary, Italy
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Tepotinib Drug-Drug Interaction Study With Itraconazole in Healthy Participants

Healthy

Germany
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Berzosertib Human Mass Balance Study (DDRiver Solid Tumors 208)

Advanced Solid Tumor

Hungary
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Effect of Hepatic Impairment on M2951 (BTK Inhibitor) PK

Hepatic Impairment

Germany
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Effect of Food on Peposertib PK

Healthy

Germany
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Drug-drug Interaction Study of Evobrutinib With Midazolam in Healthy Participants

Healthy

Germany
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Deflox Tablets Bioequivalence (BE) Trial

Healthy

Mexico
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

A Comparative Study of New Formulation and Approved Formulation for Levothyroxine in Healthy Volunteers

Healthy

Mexico
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Bioequivalence of Two Formulations of Levothyroxine Sodium 200 Micrograms (mcg) Under Tablet Form

Healthy

Brazil
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Relative Bioavailability (rBA) of Evobrutinib Intended Commercial and Clinical Tablets, and Effect of Food on Intended Commercial Tablets

Healthy

Germany
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

The Willow LTE Study With M5049 in Participants With SCLE, DLE and/or SLE (WILLOW LTE)

Systemic Lupus Erythematosus

United States, Spain, China, Korea, Republic of, Argentina, Bulgaria, Chile, Greece, Japan, Mauritius, Mexico, Moldova, Republic of, Poland, South Africa, Australia, Colombia, Philippines, Serbia
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Tepotinib Drug-Drug Interaction Study With Carbamazepine in Healthy Participants

Healthy

Germany
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Study of M5049 in CLE and SLE Participants

Systemic Lupus Erythematosus | Cutaneous Lupus Erythematosus

Spain, Bulgaria, Germany, Moldova, Republic of, North Macedonia, Ukraine
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Treatment Outcomes in Japanese RCC Patients Treated With Avelumab Plus Axitinib as First-line Therapy: Retrospective Study (J-DART2)

Renal Cell Carcinoma

Japan
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

A Study to Learn About the Study Medicine (Avelumab) in Japanese Patients With Urothelial Carcinoma That Has Spread

Urothelial Carcinoma

Japan
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

GXR RM (Glucophage® Extended Release Reduced Mass) 500 Milligram (mg) Korea Bioequivalence (BE) Study

Healthy

Korea, Republic of
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

A Study to Investigate the Association of Real-world Sensor-derived Biometric Data With Clinical Parameters and Patient-reported Outcomes for Monitoring Disease Activity in Patients With COPD

Pulmonary Disease, Chronic Obstructive

Germany
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Concor® Bioequivalence Study in Chinese Participants (Darmstadt-Nantong)

Healthy

China
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

DDI Study of Evobrutinib and Carbamazepine

Healthy

Germany
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Drug-Drug Interaction Study of Evobrutinib and Transporter Substrates

Healthy

Germany
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Bioequivalence Study of Coated Cesol Tablet Formulation Versus Biltricide

Healthy

Germany
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Effect of Meal Composition and Timing on Evobrutinib Bioavailability

Healthy

Germany
GlaxoSmithKline
Merck KGaA, Darmstadt, Germany

Terminated

A Study to Evaluate the Efficacy and Safety of Bintrafusp Alfa (M7824) Monotherapy in Metastatic or Locally Advanced Urothelial Cancer

Neoplasms

Spain, United States, France, Netherlands, Canada
UNICANCER
Merck KGaA, Darmstadt, Germany

Terminated

Evaluation of Bintrafusp Alfa in Operable and Untreated Head and Neck Squamous Cell Carcinoma (ICING)

Squamous Cell Carcinoma of Head and Neck

France
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...
Merck Serono Limited, an affiliate of Merck KGaA, Darmstadt, Germany

Completed

Effectiveness of Cladribine Tablets in Participants With Highly-active Relapsing Multiple Sclerosis (CAMELOT-MS)

Relapsing-Remitting Multiple Sclerosis

United Kingdom
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...
Merck Healthcare Germany GmbH, an affiliate of Merck KGaA, Darmstadt, Germany

Active, not recruiting

An Observational Study to Evaluate the Efficacy and Safety of Avelumab + Axitinib Combination in Participants With aRCC (AVION)

Carcinoma, Renal Cell

Germany, Greece, Belgium, Russian Federation
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...
Merck Hellas sa., Greece, an affiliate of Merck KGaA, Darmstadt, Germany

Active, not recruiting

Prospective Effectiveness and Safety Study of Cladribine in Participants Who Change First-line DMD Treatments for Multiple Sclerosis (CLAD CROSS)

Multiple Sclerosis

Greece, Switzerland, Norway, Italy, Poland, Portugal
Merck KGaA, Darmstadt, Germany
Merck Serono S.A., Geneva

Completed

Trial of MSC1936369B in Subjects With Solid Tumors

Cancer | Solid Tumors

France, Belgium, Australia, Netherlands
Merck KGaA, Darmstadt, Germany
Merck spol.s.r.o., Czech Republic

Completed

Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in Czech Republic (ECOS CZ)

Growth Disorders

Czechia
Merck KGaA, Darmstadt, Germany
Merck Gesellschaft mbH, Austria

Completed

To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in Austria (ECOS AUT)

Growth Disorders

Austria
Merck KGaA, Darmstadt, Germany
Merck Serono Limited, UK

Completed

A Retrospective Review of Liver Resection Rate in Metastatic Colorectal Cancer Patients Following Downsizing Treatment With Chemotherapy Plus Cetuximab in Normal UK National Health Service Clinical Practice (RESECT)

Metastatic Colorectal Cancer

United Kingdom
Merck KGaA, Darmstadt, Germany
Merck Serono S.P.A., Italy

Terminated

Study to Evaluate if the Addition of r-hLH (Luveris®) to FSH From Day 8 of Ovarian Stimulation is Able to Decrease Total FSH Dose and to Improve Cycle Outcome in Infertile Women Undergoing ART, Who Required High FSH Dose in a Previous Cycle (Luveris in ART)

Reproductive Techniques, Assisted

Italy
Merck KGaA, Darmstadt, Germany
Merck Pte. Ltd., Singapore

Completed

A Study Using Recombinant Human Luteinizing Hormone (r-hLH, Luveris®) in the Treatment of Chinese Women With Hypogonadotropic Hypogonadism

Hypogonadism

China
Merck KGaA, Darmstadt, Germany
Merck spol.s.r.o., Czech Republic

Completed

Post-Authorization Observational Study to Evaluate Cognition and Fatigue in Relapsing-remitting Multiple Sclerosis (RRMS) Patients Treated With Rebif® (SKORE)

Multiple Sclerosis, Relapsing-Remitting

Czech Republic
Merck KGaA, Darmstadt, Germany
Merck Serono S.P.A., Italy

Completed

Dietary Supplement of Curcumin in Subjects With Active Relapsing Multiple Sclerosis Treated With Subcutaneous Interferon Beta 1a (CONTAIN)

Multiple Sclerosis

Italy
Merck KGaA, Darmstadt, Germany
Merck Serono S.P.A., Italy

Completed

To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in Italy (ECOS ITA)

Growth Disorders

Italy

Clinical Trials Sponsored by Merck KGaA

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Ghana

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations