Clinical Trials Sponsored by Synthes GmbH

Total 3370 results

Grünenthal GmbH

Completed

A Clinical Study in Healthy Adults Who Sometimes Take Drugs for Pleasure to Investigate the Safety and Tolerability of GRT0151Y and to Find Out Which Single Dose of the Compound is Maximally Tolerated

Pain | Chronic Pain | Acute Pain

Canada
Grünenthal GmbH

Completed

A Clinical Study in Healthy Subjects Which Aims to Investigate the Safety, the Tolerability and the Effects of GRT0151Y and How the Compound is Taken up and Excreted From the Body

Acute Pain

France
Humedics GmbH

Completed

Fast-track LiveR: Study for the Early Identification of Low-risk Patients After Partial Liver Resection by the LiMAx-test

Liver Failure

Germany
Grünenthal GmbH

Completed

Efficacy and Safety of Intravenous Neridronic Acid in CRPS-I

Complex Regional Pain Syndrome, Type I

United States, Germany, United Kingdom
Phenox GmbH

Unknown

pCONUS2 Treatment of Wide Neck Intracranial Aneurysms 2 (pToWin2)

Intracranial Aneurysm
Ligartis GmbH

Withdrawn

Phase Ib/II Study Assessing the Neo-adjuvant Combination Therapy of Vinflunine With Cisplatin Followed by Radical Cystectomy in Patients With Muscle-invasive Bladder Cancer (JaNEO) (JaNEO)

Bladder Cancer

Germany
Joimax GmbH

Withdrawn

Trial to Show Non-inferiority / Superiority of an Endoscopic Transforaminal Discectomy to Standard Microdiscectomy (TESCORT)

Lumbar Disc Herniation

Austria, Germany
Novaliq GmbH

Completed

Influence of Perfluorohexyloctane (NovaTears) on Tear Film Thickness in Patients With Mild to Moderate Dry Eye Disease

Dry Eye Disease

Austria
Grünenthal GmbH

Completed

Efficacy and Tolerability of Lidocaine Plaster for Treatment of Long-term Local Nerve Pain

Pain | Chronic Pain | Postoperative Pain | Neuropathic Pain

Austria, Belgium, Brazil, Denmark, France, Italy, Spain, United Kingdom
Novaliq GmbH

Completed

NovaTears® Eye Drops Observational Study NT-002

Dry Eye Syndromes

Germany
Vasopharm GmbH

Completed

Phase 2 a Study to Assess Safety and Pharmacokinetics of VAS203 in Patients With Traumatic Brain Injury (NOSTRA)

Traumatic Brain Injury

Austria, France, Spain, Switzerland, United Kingdom
Ethicare GmbH

Unknown

Orodispersible Minitablets of Enalapril in Young Children With Heart Failure Due to Congenital Heart Disease (LENA-WP09)

Heart Failure | Congenital Heart Disease

Austria, United Kingdom, Hungary, Netherlands, Serbia
Grünenthal GmbH

Terminated

Multiple Dose Trial Comparing the Plasma Levels of Two Different Analgesic Transdermal Patch Formulations

Healthy

Germany
SportWelding GmbH

Unknown

Clinical Evaluation of the SportWelding FijiAnchor® in Hand and Hand Wrist Surgery

Lesion of Ligament of Wrist and/or Hand

Austria
Beneo GmbH

Completed

Effect of Consumption of Orafti® Inulin on Bowel Motor Function in Subjects With Constipation

Healthy | Constipation

Germany
Vaximm GmbH

Completed

VXM01 Phase I Dose Escalation Study in Patients With Locally Advanced, Inoperable and Stage IV Pancreatic Cancer

Stage IV Pancreatic Cancer

Germany
Abnoba Gmbh

Completed

Maximum Tolerable Concentration of abnobaVISCUM Fraxini Intravesically in Patients With Superficial Bladder Cancer

Superficial Bladder Cancer

Egypt, Germany
medac GmbH

Terminated

Urokinase Therapy in Patients With Diabetic Foot Syndrome

Ischemia | Diabetic Foot | Arterial Occlusive Disease

Germany
Novaliq GmbH

Completed

CyclASol® Phase 1 Study

Healthy

Germany
Eurocor GmbH

Unknown

FREERIDE STUDY, Freeway Paclitaxel Coated Balloon Catheter to Treat Peripheral Artery Disease

Peripheral Artery Disease

Germany, Italy, Austria, Colombia, Hungary, Spain
Provascular GmbH

Completed

Evaluation of Efficacy and Safety of the FlexStent Self-Expanding Stent System

Efficacy of the Study Device

Germany
medac GmbH

Completed

Fluorescence-guided Resection of Malignant Gliomas With 5-Aminolevulinic Acid

Brain Cancer | Brain Tumors | Brain Tumor, Primary | Primary Brain Tumors | Cancer of Brain
cerbomed GmbH

Completed

Transcutaneous Non-invasive Stimulation of the Vagus Nerve for the Treatment of Difficult-to-treat Epilepsy

Epilepsy

Germany
medac GmbH

Completed

Urokinase Therapy in Diabetic Foot Syndrome

Ischemia | Diabetic Foot | Arterial Occlusive Disease

Germany
Grünenthal GmbH

Terminated

Single Dose Trial Comparing the Plasma Levels of Two Different Analgesic Transdermal Patch Formulations

Healthy

Germany
Grünenthal GmbH

Completed

Bioequivalence Trial of a New Opioid Combination Compared to Reference

Healthy
CentroDerm GmbH

Not yet recruiting

Investigation of the Effect of Lipikar Baume AP+M

Actinic Keratoses
invIOs GmbH

Recruiting

PBMC-based Leukocyte Immunotherapy (PALINDROM)

Advanced Solid Tumor

Austria
iATROS GmbH

Recruiting

Clinical Study for the Investigation and Validation of a Therapy Procedure for the Adjustment of Risk Factors in Patients With Coronary Heart Disease by Means of Digital Therapy Control (ERKHA)

Cardiovascular Diseases | Coronary Artery Disease | Coronary Heart Disease | Ischemic Heart Disease

Germany
medac GmbH

Recruiting

Trial of Efficacy and Safety of MC0518 Versus Best Available Therapy in Participants With Steroid-Refractory Acute Graft Versus Host Disease (BALDER)

Steroid-refractory Acute Graft-versus-host Disease

Germany, Spain, France, Poland
InflaRx GmbH

Recruiting

Phase III Trial to Investigate Efficacy and Safety of Vilobelimab in Ulcerative Pyoderma Gangrenosum

Pyoderma Gangrenosum

United States, Spain, France, Italy, Australia, Germany, Hungary, Poland, Switzerland
Protembis GmbH

Recruiting

The PROTEMBO Trial

Severe Aortic Valve Stenosis

United States
Thermosome GmbH

Recruiting

Study of DPPG2-TSL-DOX Combined With Hyperthermia in Soft Tissue Sarcoma

Sarcoma, Soft Tissue

Germany
Peschke GmbH

Recruiting

Safety and Effectiveness of the PXL Platinum 330 System With Riboflavin Solution for Previously Untreated Corneal Ulcers

Keratitis | Corneal Ulcer

United States
JOTEC GmbH

Recruiting

A PMCF Study in Patients With Infrarenal Aortic Aneurysm Treated With the E-tegra Stent Graft System (EASY)

Vascular Aneurysm

Netherlands
CatalYm GmbH

Recruiting

First-in-Human Study of the GDF-15 Neutralizing Antibody Visugromab (CTL-002) in Patients With Advanced Cancer (GDFATHER) (GDFATHER)

Solid Tumor, Adult

Spain, Germany, Switzerland
JOTEC GmbH

Recruiting

A Study in Patients With Thoracoabdominal Aortic Aneurysm Treated With the E-nside TAAA Multibranch Stent Graft System (INNER-B)

Vascular Aneurysm

Germany
Phenox GmbH

Recruiting

Coated Mongolian Aneurysm Treatment Study 1 (COMATS 1)

Vascular Diseases | Aneurysm | Intracranial Aneurysm

Mongolia
JOTEC GmbH

Recruiting

Post-market Registry of the AMDS for the Treatment of Acute DeBakey Type I Dissection (PROTECT)

Aortic Dissection | Intramural Hematoma | Acute DeBakey I Dissection | Acute Type A Dissection

Germany
pharmaand GmbH

Completed

CATCH-R: A Rollover Study to Provide Continued Access to Rucaparib (CATCH-R)

Ovarian Cancer | Fallopian Tube Cancer | Epithelial Ovarian Cancer | Peritoneal Cancer | Other Solid Tumor | Metastatic Castration-Resistant Prostate Cancer

Israel, Italy, Canada, Russian Federation, United Kingdom, Poland
Vertanical GmbH

Completed

Efficacy and Safety of VER-01 in the Treatment of Patients With Chronic Non-specific Low Back Pain

Chronic Non-specific Low Back Pain

Germany
JOTEC GmbH

Active, not recruiting

Post Market Clinical Follow-Up Study in Patients Treated With the On-X Ascending Aortic Prosthesis (AAP) (ASCEND)

Aortic Valve Disease

United States, Spain, United Kingdom, Germany, Italy
Grünenthal GmbH

Active, not recruiting

Comparison of a Single RTX-GRT7039 and Placebo Intra-articular Injection for Pain Associated With Osteoarthritis of the Knee

Osteoarthritis

Spain, United States, Portugal, United Kingdom, Denmark
Dopavision GmbH

Active, not recruiting

MyopiaX Treatment for the Reduction of Myopia Progression in Children and Adolescents: Safety and Efficacy Investigation (MyopiaX-1)

Myopia

Spain, Netherlands, Germany, Portugal, United Kingdom
InnoRa GmbH

Completed

Treatment of Coronary De-novo Stenosis by a Sirolimus Coated Balloon or a Paclitaxel Coated Balloon Catheter (SCBDENOVO)

Coronary Artery Disease

Switzerland, Germany
JOTEC GmbH

Active, not recruiting

PMCF Study in Patients With Acute or Chronic Aortic Dissection or Aortic Aneurysm Treated With E-vita OPEN NEO (NEOS-APAC)

Aortic Aneurysm | Aortic Dissection

Thailand, Singapore, Hong Kong, Korea, Republic of, Malaysia, Australia
JOTEC GmbH

Active, not recruiting

Registry in Patients With Thoracoabdominal Aneurysms (CONNECT)

Thoracoabdominal Aneurysm

Germany
Myota GmbH

Active, not recruiting

PRebiotic Intervention for Metabolic and MEntal Health (PRIME) (PRIME)

Stress | Metabolic Syndrome | Anxiety | Mood

United Kingdom
Synimmune GmbH

Completed

FLYSYN in MRD Positive AML (FLYSYN-101)

Acute Myeloid Leukemia

Germany
pharmaand GmbH

Terminated

A Study to Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes (LODESTAR)

Solid Tumor

United States

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