Search clinical trials for: 1st Line

Total 9890 results

Italian Trial in Medical Oncology

Completed

Study Comparing Association Between Sorafenib and Interleukin-2 (IL-2) Versus Sorafenib in 1st Line Therapy in Advanced (Adv) Renal Cell Carcinoma (RCC) (ROSORC)

Renal Cell Carcinoma | Metastatic Disease

Italy
Asociacion Doctor Peset Para el Estudio de la Hematología
Cephalon; Pivotal S.L.

Unknown

Ciclophosphamide, Vincristine, Myocet and Prednisone, With Rituximab in 1st-Line Treatment for Patients With No-Hodgkin B Lymphoma and Cardiovascular (CV) Risk

No Hodgkin B Lymphoma

Spain
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Docetaxel and Carboplatin Versus Docetaxel as Second Line Treatment in Patients With Non-Small-Cell Lung Carcinoma (NSCLC)

Non-Small Cell Lung Cancer

Greece
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Randomized Trial With Vinorelbine and Gemcitabine Versus Docetaxel and Gemcitabine in Patients With Non-Small Cell Lung Cancer

Non Small Cell Lung Cancer

Greece
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Trial of Docetaxel Versus Vinorelbine as 1st Line Treatment in Elderly Patients With Non-Small-Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer

Greece
Dutch Colorectal Cancer Group
Sanofi; Hoffmann-La Roche; Koningin Wilhelmina Fonds

Completed

Sequential Versus Combination Chemotherapy in Advanced Colorectal Carcinoma

Advanced Colorectal Cancer
Veeda Oncology
Bristol-Myers Squibb; Sanofi

Completed

A Phase II Trial of Modified FOLFOX 6 and Cetuximab in First Line Treatment of Metastatic Colorectal Cancer

Colorectal Cancer

United States
Veeda Oncology
Bristol-Myers Squibb

Completed

Phase II Study of Cetuximab in Combination With Carboplatin and Docetaxel for Patients With Advanced Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States
University of Oklahoma
M.D. Anderson Cancer Center; Sanofi; Genentech, Inc.

Completed

Combination Chemotherapy for 1st Line Treatment of Advanced or Metastatic Pancreatic Cancer

Metastatic Pancreatic Cancer

United States
Sanofi

Completed

Phase II Study of Oxaliplatin in Combination With 5-Fu in 1st Line Treatment of Locally Advanced or Metastatic Squamous Cell Carcinoma of the Head and Neck

Head and Neck Cancer

France
Sanofi

Completed

TAX + Carboplatin or Cisplatin 1st Line Post-Surgery Ovarian

Ovarian Neoplasms

Korea, Republic of
Pfizer

Completed

PH 1 Evaluation Of Oral CI-1033 In Combination With Paclitaxel/ Carboplatin As 1st Line Chemotherapy In NSCLC Patients

Carcinoma, Non-Small Cell Lung

United States, Canada
Zeneus Pharma

Unknown

Myocet, Docetaxel & Trastuzumab as 1st Line Treatment of Patients With HER-2/Neu Positive Metastatic Breast Cancer

Metastatic Breast Cancer

Italy
Merck Sharp & Dohme LLC

Not yet recruiting

Substudy 06C: A Study of Sacituzumab Tirumotecan (MK-2870) With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

Esophageal Cancer | Esophageal Neoplasms | Gastroesophageal Adenocarcinoma | Gastroesophageal Junction
BriaCell Therapeutics Corporation

Recruiting

A Study of BRIA-OTS Cellular Immunotherapy in Metastatic Recurrent Breast Cancer

Breast Cancer | Cancer of Breast | Malignant Tumor of Breast | Breast Tumor | Cancer of the Breast | Tumors, Breast

United States
Dongzhimen Hospital, Beijing

Not yet recruiting

Molecular Characteristics of Phlegm-heat Syndrome in Ischemic Stroke

Ischemic Stroke, Acute

China
Aalborg University

Not yet recruiting

Investigation of Corticospinal Excitability Aspects of Itch and Pain

Pain | Itch
Ohio State University
Patient-Centered Outcomes Research Institute; Northwestern University; Preeclampsia...

Not yet recruiting

Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL (ASPIRIN)

Preeclampsia | Gestational Hypertension | Hypertensive Disorders of Pregnancy

United States
Yale University
Food and Drug Administration (FDA)

Not yet recruiting

Electronic Health Record Strategies to Promote Diverse Participation in Research AIM 2

Patient Participation

United States
Tang-Du Hospital

Recruiting

Study on the Therapeutic Effect of Irinotecan Liposomes in Small Cell Lung Cancer

Small Cell Lung Cancer

China
Second Affiliated Hospital of Xi'an Jiaotong University

Recruiting

Improvements in Thyroid Tumor Surgery and the Prognosis, Diagnosis, Recurrence and Metastasis of Patients

Carcinogenesis | Papillary Thyroid Cancer | Lymph Node Metastasis

China
Centre Hospitalier Universitaire de la Réunion

Not yet recruiting

Urinary Incontinence and Other Pelvic Floor Dysfunctions in Trail Runners (IU-TRAIL)

Urinary Stress Incontinence
Casa di Cura Dott. Pederzoli
University of Padova

Recruiting

First-day Versus Early Drain Removal Following PD: a Randomized Controlled Trial (FIDEL)

Pancreas Fistula Abdominal Drains

Italy
Hospital Nossa Senhora da Conceicao

Not yet recruiting

Complications Associated With Multiple Central Venous Accesses in the Internal Jugular Vein

Catheter Complications | Catheter Related Complication | Central Venous Catheters
M.D. Anderson Cancer Center

Not yet recruiting

Prebiotic Food-enriched Diet (PreFED) to Enhance the Microbiome and Response to First-line Immunotherapy in Unresectable Melanoma

Unresectable Melanoma

United States
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Not yet recruiting

Adebrelimab With or Without SHR-8068 in Combination With Cisplatin Plus Gemcitabine as First-line Treatment in Patients With Advanced Biliary Tract Cancer

Biliary Tract Cancer
M.D. Anderson Cancer Center

Not yet recruiting

A Phase I Study of Hyper-CVAD In Combination With Venetoclax In Pediatric Patients With Relapsed or Refractory Acute Leukemias That Are of the Lymphoid Lineage Including Bi-Phenotypic or Undifferentiated Leukemias

Refractory Acute Leukemia | Undifferentiated Leukemia | Relapsed Acute Leukemia | Bi-Phenotypic Leukemia

United States
Gruppo Oncologico Italiano di Ricerca Clinica

Recruiting

AGNOSTIC THERAPY IN A PHASE II SINGLE-ARM STUDY IN FIRST-LINE TREATMENT OF DURVALUMAB IN ASSOCIATION WITH CARBOPLATIN OR CISPLATIN AND ETOPOSIDE IN PATIENTS AFFECTED BY EXTENSIVE STAGE - EXTRAPULMONARY SMALL CELL CARCINOMA (DURVASCC)

Extrapulmonary Small Cell Carcinoma

Italy
The First Affiliated Hospital of Henan University...

Not yet recruiting

Adebrelimab in Combination With Apatinib and Chemotherapy/Chemoradiotherapy in Immuno-experienced Second-line ESCC.

Esophageal Cancer

China
University of Toronto
University Health Network, Toronto; Sunnybrook Health Sciences Centre; Unity...

Not yet recruiting

Comprehensive Health Assessment for My Plan: Initial Implementation Study (CHAMP Implementation Study)

Cancer | Older Adults
Marmara University

Recruiting

Evaluation of Inflammasome Gene Polymorphisms in Periodontitis Patients

Periodontitis | Periodontal Diseases

Turkey
Chang Gung University
Chang Gung Memorial Hospital

Recruiting

Development and Evaluation of Online Interactive Podcast Program "Living With Type 1 Diabetes to Grown-Up"

Type 1 Diabetes Mellitus

Taiwan
Sidney Kimmel Comprehensive Cancer Center at Johns...
Maryland Cigarette Restitution Fund

Recruiting

Behavioral Weight Loss for Cancer Survivors in Maryland: A Trial With Adaptive Interventions (Helpline)

Weight Loss

United States
Zhou Chengzhi
Guangdong Provincial Hospital of Traditional Chinese Medicine; Sun Yat-sen... and other collaborators

Not yet recruiting

Liposomal Irinotecan Combination Regimen for First-line Treatment of Small Cell Lung Cancer

Small Cell Lung Cancer
Intermountain Health Care, Inc.
Impactiv, Inc.

Recruiting

Live and Interactive Fitness Training Program (Vivo Knee OA) (LIFT-OA)

Knee Osteoarthritis

United States
Taipei Veterans General Hospital, Taiwan
National Yang Ming Chiao Tung University

Recruiting

Exploring Physical and Psychological Needs and Quality of Life in Patients With Advanced Cancer Receiving Immunotherapy

Quality of Life | Cancer | Immunotherapy | Distress, Emotional | Financial Toxicity | IrAE | Care Need

Taiwan
Kaplan Medical Center

Recruiting

Intra-articular Allocetra in Osteoarthritis of the 1st Carpo-metacarpal Joint

Osteoarthritis Thumb

Israel
Shanghai Chest Hospital

Not yet recruiting

A Comparative Study Evaluating the Vein of MArshall Ethanol Infusion Ablation Using an Over-the-wire (OTW) Balloon Versus a microcatHeter in Patients With Atrial Fibrillation

Atrial Fibrillation | Atrial Flutter

China
Merck Sharp & Dohme LLC
GOG Foundation; European Network of Gynaecological Oncological Trial Groups...

Not yet recruiting

A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)

Cervical Cancer
Institut Curie

Not yet recruiting

Efficacy of Personalized Tumorogram-based Therapy in Cancer Established From Patient-derived Organoid (AVATAR)

Metastatic Breast Cancer

France
Lee's Pharmaceutical Limited

Not yet recruiting

Phase III Study of Socazolimab as First-Line Treatment in Persistent, Recurrent, or Metastatic Cervical Cancer

Cervical Cancer
Shuxiu Wang

Not yet recruiting

Application of THRIVE in Burn Children With Suspected Difficult Airway

Intubation; Difficult or Failed
Port Said University

Recruiting

Determining the Prevalence of Primary and Secondary Central Line Associated Blood Stream Infection (CLABSI) at the Tertiary Care Hospital (Microbiology)

Central Line-associated Bloodstream Infection (CLABSI)

Egypt
Ningbo No. 1 Hospital

Recruiting

First-line Treatment of PCNSL With the Combination of Orelabrutinib, Rituximab, and Methotrexate (ORM Regimen)

Primary Central Nervous System Lymphoma

China
University Health Network, Toronto
Academic Medical Organization of Southwestern Ontario; York University; Toronto...

Not yet recruiting

Online Psychology Program for Chronic Pain After Surgery (ADOPT-TPS)

Pain, Acute | Pain, Chronic | Post-surgical Pain | Post-Surgical Pain, Chronic

Canada
Peking Union Medical College Hospital

Recruiting

Orelabrutinib Combined With Obinutuzumab and Lenalidomide (OGL Regimen) as First-line Treatment for Marginal Zone Lymphoma.

Marginal Zone Lymphoma

China
Jin-hong Chen

Not yet recruiting

Cadonilimab Combined With Regorafenib as A Third-line Treatment in Patients With MSS CRLM

CRC

China
University of Toronto
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

Multiple Risk Factor Intervention Trial in Breast Cancer Survivors (MsFITBC)

Sedentary Behavior | Metabolic Disturbance | Breast Cancer Female

Canada
Tianjin Medical University Cancer Institute and...

Not yet recruiting

Phase Ib/II Clinical Study of Adebrelimab in Combination With Decitabine, Albumin-bound Paclitaxel, and Gemcitabine for the First-line Treatment of Metastatic Pancreatic Cancer

Metastatic Pancreatic Cancer | Decitabine | Adebrelimab (SHR-1316)

China
Liverpool Heart and Chest Hospital NHS Foundation...
Biolife LLC

Not yet recruiting

Statseal® for Central Venous Catheter Insertion Sites in Critical Care (SCENIC)

Vascular Access | Critical Care | Central Venous Catheter | Central Line | Hemostatic

United Kingdom

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