Search clinical trials for: Brain Stem Glioma

Total 52193 results

Oslo University Hospital

Completed

Safe Study of Dendritic Cell (DC) Based Therapy Targeting Tumor Stem Cells in Glioblastoma

Glioblastoma | Brain Tumor
Duke University
National Cancer Institute (NCI)

Completed

Genetic Study in Patients Receiving Treatment for Hodgkin's Disease or Childhood Brain Tumor

Lymphoma | Brain and Central Nervous System Tumors

United States
Duke University
National Cancer Institute (NCI)

Completed

Imatinib Mesylate, Vatalanib, and Hydroxyurea in Treating Patients With Recurrent or Relapsed Malignant Glioma

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Completed

RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Myxopapillary Ependymoma | Adult Oligodendroglioma | Adult Pilocytic Astrocytoma | Adult Pineal Gland... and other conditions

United States
Hospital Sant Joan de Deu
Fundació Sant Joan de Déu; Spanish National Health System

Completed

Irinotecan in Combination With Cisplatin in Pediatric Patients With Unfavorable Prognosis Gliomas

Pediatric High Risk Gliomas

Spain
NYU Langone Health
National Cancer Institute (NCI)

Withdrawn

Carboplatin, Temozolomide, and Filgrastim in Treating Patients With Newly Diagnosed or Recurrent High-Grade Glioma

Brain and Central Nervous System Tumors

United States
Martin-Luther-Universität Halle-Wittenberg
Merck KGaA, Darmstadt, Germany

Terminated

Cilengitide and Metronomic Temozolomide for Relapsed or Refractory High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas in Children and Adolescents (HGG-CilMetro)

Gliomas

Germany
University of South Florida
National Cancer Institute (NCI)

Terminated

Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer

Cancer

United States
City of Hope Medical Center

Completed

Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2

Glioblastoma | Brain Tumor | Gliosarcoma | Anaplastic Astrocytoma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Giant Cell Glioblastoma | Anaplastic Meningioma | Mixed Glioma | Brain Stem Glioma | Ependymoblastoma | Grade III Meningioma | Meningeal Hemangiopericytoma | Pineal Gland Astrocytoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

High-Dose Chemotherapy Plus Autologous Stem Cell Transplantation Compared With Intermediate-Dose Chemotherapy Plus Autologous Stem Cell Transplantation With or Without Isotretinoin in Treating Young Patients With Recurrent High-Grade Gliomas

Brain Tumor | Central Nervous System Tumor

United States, Canada, Australia
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); PTC Therapeutics

Completed

PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Completed

CC-8490 in Treating Patients With Recurrent or Refractory High-Grade Gliomas

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Completed

CC-5013 in Treating Patients With Recurrent Glioma

Brain and Central Nervous System Tumors

United States
Hadassah Medical Organization

Completed

Palliative Re-irradiation for Progressive Diffuse Intrinsic Pontine Glioma (DIPG) in Children

Pediatric Malignant Brain Tumor -Diffuse Intrinsic Pontine Glioma

Israel
St. Jude Children's Research Hospital
AstraZeneca; The Cure Starts Now Foundation; Tyler's Treehouse

Completed

Clinical Trial Evaluating the Combination of Vandetanib and Dasatinib During and After Radiation Therapy (RT) in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG)

Diffuse Intrinsic Pontine Glioma

United States
Emory University

Completed

Phase II Study of Carmustine, Streptozocin, and Mercaptopurine for Refractory or Recurrent Brain Neoplasms

Glioblastoma Multiforme | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Recurrent Brain Tumor | Mixed Gliomas
Indiana University
Indiana University Melvin and Bren Simon Cancer Center

Completed

Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors

Brain and Central Nervous System Tumors | Drug/Agent Toxicity by Tissue/Organ | Bone Marrow Suppression

United States
Children's Hospital of Philadelphia

Terminated

Paclitaxel Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Completed

Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumors

Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Recurrent Ovarian Carcinoma | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Recurrent Renal Cell Carcinoma | Stage III Renal Cell Cancer | Stage IV Skin Melanoma | Recurrent Non-Small Cell... and other conditions

Canada
Vanderbilt University
National Cancer Institute (NCI)

Withdrawn

Early Enteral Tube Feedings in Children Receiving Chemo for AML/MDS & High Risk Solid Tumors

Sarcoma | Kidney Cancer | Leukemia | Solid Tumor | Brain and Central Nervous System Tumors | Neuroblastoma | Liver Cancer
National Cancer Institute (NCI)

Terminated

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

Unspecified Childhood Solid Tumor, Protocol Specific | Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Recurrent Childhood Acute Lymphoblastic Leukemia | T-cell Large Granular Lymphocyte Leukemia | T-cell Childhood Acute Lymphoblastic... and other conditions

United States, Canada
Cedars-Sinai Medical Center

Completed

Immunotherapy for Patients With Brain Stem Glioma and Glioblastoma

Glioblastoma | Brain Stem Glioma

United States
University of Minnesota

Completed

Metabolic Syndrome in Childhood Cancer Survivors

Sarcoma | Lymphoma | Leukemia | Metabolic Syndrome | Brain and Central Nervous System Tumors

United States
Children's Oncology Group
National Cancer Institute (NCI)

Withdrawn

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Leukemia | Brain and Central Nervous System Tumors
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors

Unspecified Childhood Solid Tumor, Protocol Specific | Brain and Central Nervous System Tumors

Canada, United States
National Cancer Institute (NCI)

Terminated

Imatinib Mesylate With or Without Radiation Therapy in Treating Young Patients With Newly Diagnosed or Recurrent Glioma

Brain and Central Nervous System Tumors

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma

Brain Tumors | Central Nervous System Tumors

United States, Canada, Netherlands, Puerto Rico, Switzerland, Australia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Brain Stem Glioma

Brain Tumors | Central Nervous System Tumors

United States, Canada, Netherlands, Puerto Rico, Switzerland
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid Tumors

Cancer

United States, Australia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Followed by Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent Medulloblastoma or CNS Germ Cell Tumors

Brain Tumor | Central Nervous System Tumor

United States, Canada, Puerto Rico, Australia, Netherlands, Switzerland
Duke University
National Cancer Institute (NCI)

Completed

Temozolomide in Treating Patients With Progressive Low-Grade Glioma

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Completed

ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Withdrawn

Genetically Modified Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Completed

Gefitinib and Radiation Therapy in Treating Children With Newly Diagnosed Gliomas

Untreated Childhood Brain Stem Glioma | Untreated Childhood Anaplastic Astrocytoma | Untreated Childhood Anaplastic Oligodendroglioma | Untreated Childhood Giant Cell Glioblastoma | Untreated Childhood Glioblastoma | Untreated Childhood Gliomatosis Cerebri | Untreated Childhood Gliosarcoma | Untreated...

United States
National Cancer Institute (NCI)

Completed

Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Recurrent Childhood Anaplastic Astrocytoma | Recurrent Childhood Brain Stem Glioma | Recurrent Childhood Giant Cell Glioblastoma | Recurrent Childhood Glioblastoma | Recurrent Childhood Gliosarcoma | Recurrent Childhood Oligodendroglioma

United States
National Cancer Institute (NCI)

Completed

Tipifarnib and Radiation Therapy in Treating Young Patients With Brainstem Glioma

Untreated Childhood Brain Stem Glioma

United States
National Cancer Institute (NCI)

Completed

Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer

Radiation Toxicity | Malignant Neoplasm | Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Mixed Glioma | Adult Oligodendroglioma | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the... and other conditions

United States
Helsinki University Central Hospital
Turku University Hospital; Oulu University Hospital; Kuopio University Hospital; Tampere University Hospital

Completed

ANGIOCOMB Antiangiogenic Therapy for Pediatric Patients With Diffuse Brain Stem and Thalamic Tumors

Brainstem Glioma

Finland
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors

Sarcoma | Neuroblastoma | Brain Tumors | Central Nervous System Tumors

United States, Canada, Australia
Legacy Health System
DUSA Pharmaceuticals, Inc.

Unknown

A Study of Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Malignant Glial Tumors of the Brain (ALA)

Glioma

United States
INSYS Therapeutics Inc
National Cancer Institute (NCI)

Completed

Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain

Cancer

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Chemotherapy and Radiation Therapy After Surgery in Treating Children With Newly Diagnosed Astrocytoma, Glioblastoma Multiforme, Gliosarcoma, or Diffuse Intrinsic Pontine Glioma

Brain and Central Nervous System Tumors

United States, Canada, Australia, Switzerland, Puerto Rico, Netherlands, New Zealand
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy Plus Carboplatin and Lobradimil in Treating Children With Newly Diagnosed Brain Stem Gliomas

Brain and Central Nervous System Tumors

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Development of Strategies to Increase Enrollment in Clinical Trials for Children With Cancer

Sarcoma | Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Leukemia | Ovarian Cancer | Brain and Central Nervous System Tumors | Neuroblastoma | Liver Cancer | Psychosocial Effects of Cancer and Its Treatment | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

United States, Puerto Rico, Canada, Switzerland
University of South Florida
National Cancer Institute (NCI)

Completed

Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment

Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Myelodysplastic Syndromes | Leukemia | Brain Tumor | Cachexia | Myelodysplastic/Myeloproliferative Diseases | Central Nervous System Tumors

United States, Canada, Puerto Rico
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma

Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Small Intestine Cancer | Brain and Central Nervous System Tumors | Lymphoproliferative Disorder

United States, Canada
Children's Hospital Medical Center, Cincinnati
National Cancer Institute (NCI)

Completed

Combination Chemotherapy and Radiation Therapy in Treating Younger Patients Who Are Undergoing an Autologous Stem Cell Transplant for Newly Diagnosed Gliomas

Brain and Central Nervous System Tumors
University of Pittsburgh
National Cancer Institute (NCI)

Completed

Calcitriol Plus Carboplatin in Treating Patients With Advanced Solid Tumors

Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific

United States
Gesellschaft fur Padiatrische Onkologie und Hamatologie...

Unknown

Combination Chemotherapy and Radiation Therapy With or Without Methotrexate in Treating Young Patients With Newly Diagnosed Gliomas

Brain and Central Nervous System Tumors

United States
Children's Hospital Los Angeles

Unknown

Combination Chemotherapy With or Without Etoposide Followed By an Autologous Stem Cell Transplant in Treating Young Patients With Previously Untreated Malignant Brain Tumors

Brain and Central Nervous System Tumors

United States, Canada, Australia, Switzerland, New Zealand

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